Ann Emerg Med [JOURNAL]

Sun 200 papers

RSS

Can We Pioneer a Traumatic Brain Injury Blood Test in Trauma Patients Being Considered for Computed Tomography Scanning of the Head?

Papa L

Ann Emerg Med · 2026 May · PMID 41575404 · Publisher ↗

Abstract loading — click title to view on PubMed.

Get PDF PubMed ↗

Emergence of Medetomidine in the Illicit Drug Supply: Implications for Emergency Care and Withdrawal Management.

Lynch MJ, Pizon AF, Yealy DM

Ann Emerg Med · 2026 Jun · PMID 41575403 · Publisher ↗

The US illicit drug supply continues to evolve with increasingly dangerous adulterants, with medetomidine a new agent seen in acute care and other practice settings. We reviewed available literature on illicit drug adult... The US illicit drug supply continues to evolve with increasingly dangerous adulterants, with medetomidine a new agent seen in acute care and other practice settings. We reviewed available literature on illicit drug adulterants, medetomidine intoxication, and sequelae. Although little is known about withdrawal and the clinical manifestations are stark, we reviewed the best available literature on dexmedetomidine withdrawal and suggest approaches for treatment.

Get PDF PubMed ↗

Nonoperative Management of Uncomplicated Appendicitis: The Elephant in the (Emergency) Room?

Chun TH, Minneci PC

Ann Emerg Med · 2026 Jun · PMID 41575402 · Publisher ↗

Abstract loading — click title to view on PubMed.

Get PDF PubMed ↗

Dexamethasone Treatment Regimen and Clinical Outcomes in Children With Asthma Exacerbations.

Dave S, Green-Hopkins I, Bardach NS … +2 more , Grupp-Phelan J, Shapiro DJ

Ann Emerg Med · 2026 Jul · PMID 41575401 · Publisher ↗

STUDY OBJECTIVES: To detail variation in the number of doses of dexamethasone used to treat children with asthma exacerbations discharged from the emergency department (ED) and to assess whether treatment with 1 dose ver... STUDY OBJECTIVES: To detail variation in the number of doses of dexamethasone used to treat children with asthma exacerbations discharged from the emergency department (ED) and to assess whether treatment with 1 dose versus 2 doses was associated with different clinical outcomes. We hypothesized that clinical outcomes would not differ between groups. METHODS: We conducted a retrospective cohort study of children aged 2 to 20 years discharged from either of 2 EDs after treatment with dexamethasone for an asthma exacerbation. The primary outcome was an ED revisit, and the secondary outcome was a hospitalization, each measured within 14 days. The primary exposure was prescription of a second dose of dexamethasone at discharge. Propensity score adjustment with inverse probability of treatment weighting was used to mitigate confounding. RESULTS: Among 2,063 children included, 1,277 (61.9%) were prescribed a second dose of dexamethasone. In the propensity score-weighted cohort, the risk of an ED revisit was 5.2% for children who received 1 dose and 5.7% for children who received 2 doses (risk difference, 0.45%, 95% confidence interval [CI]: -1.4% to 2.3%). The risk of hospitalization was 0.85% in the 1-dose group and 0.83% in the 2-dose group (risk difference 0.02%, 95% CI: -0.93% to 0.89%). CONCLUSION: Nearly two-thirds of children with asthma exacerbations were treated with 2 doses of dexamethasone rather than a single dose, even though treatment with 2 doses was not associated with improved outcomes. These results suggest that 1 dose of dexamethasone may be sufficient to treat many children with asthma exacerbations discharged from the ED.

Get PDF PubMed ↗