Am J Ther [JOURNAL]

Xanthopoulos A, Giamouzis G, Papamichalis M … +7 more , Leventis I, Briasoulis A, Magouliotis DE, Triposkiadis F, Starling RC, Verbrugge FH, Skoularigis J

Am J Ther · 2026 Feb · PMID 41634913 · Publisher ↗

Abstract loading — click title to view on PubMed.

Get PDF PubMed ↗

Comment on "Risk of Pericarditis Recurrence Associated With Rilonacept and NSAID/Colchicine Therapy After Initial Pericarditis Presentation: A Retrospective Real-World Comparative Risk Analysis With TriNetX".

Parameswaran V, Wang S, Clair J

Am J Ther · 2026 Mar-Apr 01 · PMID 41610184 · Full text

Abstract loading — click title to view on PubMed.

Free PDF PubMed ↗

Comments on "SGLT2 Inhibitors in Patients Undergoing Tricuspid Valve Transcatheter Edge-to-Edge Repair".

Sohn JT

Am J Ther · 2026 Jan · PMID 41572448 · Publisher ↗

Abstract loading — click title to view on PubMed.

Get PDF PubMed ↗

Reversible Lurasidone-Induced Tardive Retrocollis Managed With Aripiprazole.

Shiao YC, Chen WT, Yeh YW … +2 more , Kuo SC, Chen CY

Am J Ther · 2026 Jan · PMID 41566498 · Publisher ↗

Abstract loading — click title to view on PubMed.

Get PDF PubMed ↗

Drug Reaction With Eosinophilia and Systemic Symptoms Syndrome Induced by Abiraterone: Evidence From a Positive Rechallenge.

Agrebi M, Sahnoun D, Bouraoui H … +5 more , Zouaghi S, Yacoub S, Belkahla M, Najet G, Ben Salem C

Am J Ther · 2026 Jan · PMID 41555496 · Publisher ↗

Abstract loading — click title to view on PubMed.

Get PDF PubMed ↗

Comparative Microbiome Analysis in Ventilator-Associated Pneumonia Across Oral Care Interventions in Intubated Patients: A Systematic Review and Meta-Analysis.

Sridharan K, Sivaramakrishnan G

Am J Ther · 2026 Jan · PMID 41555483 · Publisher ↗

Abstract loading — click title to view on PubMed.

Get PDF PubMed ↗

Leucovorin for Autism.

Naguy A

Am J Ther · 2026 Jan · PMID 41543930 · Publisher ↗

Abstract loading — click title to view on PubMed.

Get PDF PubMed ↗

Long-Acting Injectable Antipsychotics in Child and Adolescent Psychiatry.

Naguy A, Abul HH, Alamiri B

Am J Ther · 2026 Jan · PMID 41543929 · Publisher ↗

Abstract loading — click title to view on PubMed.

Get PDF PubMed ↗

Therapeutic Advances in the Management of Cardiogenic Shock.

Filipescu R, Collins SP, Radu RI … +17 more , Ben Gal T, Antohi L, Abdelhamid M, Geavlete O, Pana M, Farmakis D, Matei DC, Savarese G, Margineanu C, Polovina M, Miró Ò, Guz D, Palazzuoli A, Masip J, Adamo M, Ambrosy AP, Chioncel O

Am J Ther · 2026 Mar-Apr 01 · PMID 41543923 · Publisher ↗

BACKGROUND: Despite the use of vasoactive therapies, invasive monitoring, revascularization, and/or mechanical circulatory support (MCS), cardiogenic shock (CS) continues to be associated with very high mortality. This n... BACKGROUND: Despite the use of vasoactive therapies, invasive monitoring, revascularization, and/or mechanical circulatory support (MCS), cardiogenic shock (CS) continues to be associated with very high mortality. This narrative review aims to describe the therapeutic advances in the management of this syndrome. AREAS OF UNCERTAINTY: In clinical practice, many uncertainties about CS management remain, particularly regarding management in pre-CS phase, risk stratification algorithms, optimal ventilation mode, local CS protocols, appropriate selection and threshold for MCS initiation, or approach to MCS-related complications. Patients with CS without acute myocardial infarction (AMI) are substantially underrepresented in randomized controlled trials (RCTs), and future research, including new RCTs and high-quality observational studies, is imperiously needed. DATA SOURCES: Evidence-based information on CS is limited, as management recommendations and therapies are mostly extrapolated from large multicentric CS registries or RCTs in patients with AMI occurring at tertiary medical centers. In recent years, numerous studies have been published or are ongoing, emphasizing the unresolved issues in CS management. RESULTS: The results from the literature showcased the benefits of early revascularization of the culprit vessel in AMI-CS or use of pulmonary artery catheter for better overall monitoring. Despite almost universal administration of inotropes and vasopressors in patients with CS, they lack RCT evidence for increasing the survival rate. The same applies for temporary MCS, except for micro axial flow pumps which have been associated with lower 6-month mortality in a selected CS population. Large tertiary CS centers could develop regional or national networks through hub-and-spoke systems based on multidisciplinary teams and CS protocols. CONCLUSIONS: Although the current general approach to treating patients with CS has improved the prognosis, additional research is needed to overcome the key knowledge gaps and advance individualized CS treatment.

Get PDF PubMed ↗