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Prescrire Int [JOURNAL]

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Delamanid (Deltyba°) and multidrug-resistant pulmonary tuberculosis.

Prescrire Int · 2017 Apr · PMID 30730656

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Osteoarthritis of the knee.

Prescrire Int · 2017 Mar · PMID 30730623

As of mid-2016, there is still no evidence that hyaluronic acid is more effective than placebo in osteoarthritis of the knee. It does however have adverse effects. As of mid-2016, there is still no evidence that hyaluronic acid is more effective than placebo in osteoarthritis of the knee. It does however have adverse effects.

Graves' disease in adults Antithyroid drugs, radioactive iodine, or sometimes thyroidectomy.

Prescrire Int · 2017 Mar · PMID 30730622

What is the best treatment for adults with Graves' disease in 2016? To answer this question, we reviewed the literature using the standard Prescrire methodology. When the symptoms of hyperthyroidism are poorly tolerated,... What is the best treatment for adults with Graves' disease in 2016? To answer this question, we reviewed the literature using the standard Prescrire methodology. When the symptoms of hyperthyroidism are poorly tolerated, a beta-blocker relieves tachy- cardia, anxiety and tremor. Three treatments have been shown to be effec- tive in controlling hyperthyroidism: antithyroid drugs, radioiodine, and thyroidectomy. Carbimazole and its metabolite thiamazole are the antithyroid drugs with the best harm-benefit balance, except during the first trimester of preg- nancy. About 50% of patients are cured after 12 to 18 months of treatment. Antithyroid drugs carry a risk of rare but serious adverse effects, including agranulocytosis. Hepa- titis is more frequent with propylthiouracil. Radioiodine is administered as a single oral dose, in order to destroy the thyroid gland. Perma- nent cure is achieved in about 80% of cases, usu- ally after 1 or 2 months. Permanent hypothyroid- ism is frequent, occurring at various intervals after treatment. Radioiodine may exacerbate pre-existing oph- thalmopathy or provoke its onset, especially among smokers. Corticosteroid therapy reduces this risk. Protective measures are used for a few days or weeks in order to avoid radiation exposure among close contacts. Radioiodine is contraindi- cated during pregnancy. Surgical thyroidectomy may be total with little risk of recurrence, or subtotal with about an 8% risk of recurrence. The complications of surgery mainly consist of. hypoparathyroidism and permanent paralysis of the recurrent laryngeal nerve, which occur after 1% to 5% of procedures. In practice, the choice of treatment depends on the patient's preferences and situation, including a woman's desire to conceive, size of the goitre, the degree of hyperthyroidism, and the presence of ophthalmopathy.

Pegloticase: withdrawal of its European marketing authorisation is welcome.

Prescrire Int · 2017 Mar · PMID 30730621

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Drug-induced diarrhoea.

Prescrire Int · 2017 Mar · PMID 30730620

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Capsaicin (QUTENZA*) and diabetic neuropathic pain Harmful, and no tangible efficacy.

Prescrire Int · 2017 Mar · PMID 30730619

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tedizolid (SIVEXTRO*) in skin and soft-tissue infections.

Prescrire Int · 2017 Mar · PMID 30730618

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Secukinumab and psoriatic arthritis.

Prescrire Int · 2017 Mar · PMID 30730617

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Secukinumab (Cosentyx°) and plaque psoriasis.

Prescrire Int · 2017 Mar · PMID 30730616

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Switzerland: community pharmacists providing consultations for common medical conditions.

Prescrire Int · 2017 Feb · PMID 30726638

In Switzerland, pharmacists have set up a con- sultation service for common medical conditions in community pharmacies, in collaboration with doctors providing video consultations. Initial evaluations show the value of t... In Switzerland, pharmacists have set up a con- sultation service for common medical conditions in community pharmacies, in collaboration with doctors providing video consultations. Initial evaluations show the value of the service in terms of access to healthcare and the manage- ment of common health problems.

The French "transparency" database: what are the "agreements" between Prescrire and drug companies?

Prescrire Int · 2017 Feb · PMID 30726637

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Metastatic colorectal cancer.

Prescrire Int · 2017 Feb · PMID 30726636

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Mosquito and tick bites: individual prophylaxis First-choice treatments.

Prescrire Int · 2017 Feb · PMID 30726635

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Benfluorex: adverse effects reviewed, 1976-2015.

Prescrire Int · 2017 Feb · PMID 30726634

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Long-acting injectable olanzapine: post-injection syndrome.

Prescrire Int · 2017 Feb · PMID 30726633

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Hormonal contraceptive + enzyme inducer: unintended pregnancies.

Prescrire Int · 2017 Feb · PMID 30726632

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Extrapyramidal disorders with domperidone.

Prescrire Int · 2017 Feb · PMID 30726631

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Entecavir (Baraclude°) and chronic hepatitis B in children.

Prescrire Int · 2017 Feb · PMID 30726630

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Idebenone (Raxone°) and Leber hereditary optic neuropathy.

Prescrire Int · 2017 Feb · PMID 30726629

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Perampanel (Fycompa°) and refractory generalised epilepsy.

Prescrire Int · 2017 Feb · PMID 30726628

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