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The British Journal Of Surgery[JOURNAL]

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Diagnostic performance of the second-generation Wavelia microwave breast imaging system: a pilot clinical investigation.

Kerin EP, O'Donnell JPM, Abd Elwahab SM … +9 more , Butler TO, Bouz Mkabaah L, Fasoula A, Papatrechas G, Arvanitis P, Duchesne L, Barry MK, Lowery AJ, Kerin MJ

Br J Surg · 2025 Nov · PMID 41218979 · Full text

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Rapid evaporative ionization mass spectrometry in surgery: a systematic review.

Barber ARJ, Dottore A, Leigh J … +2 more , Fear M, Wood F

Br J Surg · 2025 Nov · PMID 41218978 · Full text

BACKGROUND: Rapid evaporative ionization mass spectrometry (REIMS) is an emerging technology facilitating real-time intraoperative tissue identification during surgery. This review aims to discuss the applications and re... BACKGROUND: Rapid evaporative ionization mass spectrometry (REIMS) is an emerging technology facilitating real-time intraoperative tissue identification during surgery. This review aims to discuss the applications and reported outcomes of REIMS technology in a surgical context. METHODS: A systematic review was performed using four electronic databases that were searched in August 2025: MEDLINE, Emcare, Embase, and Web of Science. Eligible studies were peer-reviewed, included five or more patients, and evaluated REIMS technology in the context of a surgical specialty or pathology. Two independent reviewers screened studies, extracted data, and assessed risk of bias using the QUADAS-2 tool. The study protocol was registered in the PROSPERO international prospective register of systematic reviews before commencing the review (CRD42024546741). RESULTS: A total of 344 records underwent initial screening, with 26 studies included. Included articles originated from seven countries and applied REIMS to eight surgical specialties. Twenty-three of the included articles used REIMS to identify cancerous tissue. All included studies reported both qualitative and quantitative outcomes. Included studies demonstrated a variety of surgical applications with promising results with regard to accuracy, sensitivity, and specificity. Both ex vivo and in vivo applications were explored, but limited in vivo data was reported and logistical limitations were identified. CONCLUSION: Most of the evidence supporting the use of REIMS in surgery originates from an ex vivo environment. Current limitations of the technique include equipment logistics and the complexity of interpretation of data and further in vivo studies with larger patient numbers are required to support more widespread application.

Secondary analysis of data from the HeLiX trial regarding the association between estimated blood loss and post-hepatectomy outcomes: towards the definition of a minimal clinically significant difference.

Hallet J, Ribeiro T, Fong ZV … +6 more , Perri G, Ghorbani P, Sparrelid E, Marchegiani G, Karanicolas PJ, HPB CONCEPT Team

Br J Surg · 2025 Nov · PMID 41217435 · Full text

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The science and art of decision-making in surgery.

Bisset CN, Baigrie R, Dames N … +17 more , Corbett S, Hill S, Macdermid E, Sier VQ, van der Vorst JR, Rehman U, Sarwar MS, Brennan PA, Cleland J, Ellis R, Bryan JE, Ketley A, Morgan JL, Gogalniceanu P, Kaafarani HMA, Liang R, Moug SJ

Br J Surg · 2025 Nov · PMID 41212614 · Publisher ↗

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Nationwide outcomes of 1000 robotic pancreatoduodenectomies across the four phases of the learning curve.

Emmen AMLH, van den Broek BLJ, Hendriks TE … +23 more , Busch OR, Bonsing BA, Cappelle ML, Coene PLO, Festen S, van der Harst E, de Hingh IHJT, van Laarhoven CJHM, Lips DJ, Sprakel J, Luyer MDP, Mieog JSD, van Santvoort HC, van der Schelling G, Wijsman JH, Patijn GA, de Wilde RF, Zwart MJW, Derksen WJM, Molenaar IQ, Groot Koerkamp B, Besselink MG, Members of the Dutch Institute for Clinical Auditing and the Dutch Pancreatic Cancer Group

Br J Surg · 2025 Nov · PMID 41206577 · Full text

BACKGROUND: Robotic pancreatoduodenectomy (RPD) is increasingly being implemented to enhance patient recovery, but it is unclear what happens to patient outcomes after the initial learning curve. The aim of this study wa... BACKGROUND: Robotic pancreatoduodenectomy (RPD) is increasingly being implemented to enhance patient recovery, but it is unclear what happens to patient outcomes after the initial learning curve. The aim of this study was to evaluate the first 1000 consecutive RPD performed in the Netherlands. METHODS: A nationwide analysis of patients who underwent RPD in 13 centres (March 2016-August 2023) from the Dutch Pancreatic Cancer Audit was performed. Patients were grouped based on published learning curve cut-offs (phases 1-4): 1-15, 16-62, 63-84, and >84 RPD per centre respectively. Outcomes were compared between the four learning curve phases. Ideal Outcome rates were used to compare outcomes between centres. RESULTS: Overall, 1000 patients after RPD were included. The conversion rate was 10.1%, the rate of Clavien-Dindo complications of grade ≥III was 41.3%, the rate of postoperative pancreatic fistula of grade B/C was 24.4%, and the rate of in-hospital/30-day mortality was 3.9%. Of the patients, 71.1% had a high updated alternative fistula risk score. Improvements between the phases were found for five outcomes: median operating time (420, 360, 349, and 369 min respectively; P < 0.001), conversion rate (21.7%, 10.0%, 2.8%, and 7.5% respectively; P < 0.001), rate of delayed gastric emptying (DGE) of grade B/C (32.3%, 22.6%, 15.4%, and 20.2% respectively; P = 0.003), reoperation rate (9.9%, 11.3%, 9.8%, and 4.9% respectively; P = 0.026), and median duration of hospital stay (12, 11, 10, and 10 days respectively; P = 0.035). The rate of Clavien-Dindo complications of grade ≥III and the rate of in-hospital/30-day mortality remained stable. The Ideal Outcome rate (mean 47%) did not differ between centres. CONCLUSION: Across four learning curve phases in a nationwide cohort, improvements were observed for operating time, conversion rate, rate of DGE of grade B/C, reoperation rate, and duration of hospital stay.

Endovascular aortic arch repair with a triple branch arch device.

Grasso EC, Aru RG, Pennetta FF … +3 more , Le Houérou T, Fabre D, Haulon S

Br J Surg · 2025 Nov · PMID 41206576 · Publisher ↗

INTRODUCTION: Repair of aortic arch aneurysms is challenging whether by open surgery or endovascular techniques. The aim of this study was to analyse the midterm outcomes of an innovative endovascular thoracic aortic ste... INTRODUCTION: Repair of aortic arch aneurysms is challenging whether by open surgery or endovascular techniques. The aim of this study was to analyse the midterm outcomes of an innovative endovascular thoracic aortic stent-graft with a triple branch design (Cook Medical, Bloomington, IN, USA) and to compare the outcomes in patients with a retrograde or an antegrade branch for the left common carotid artery (LCCA). METHODS: All patients treated with the custom-made triple-branch arch device between October 2018 and April 2025 at a single tertiary-care hospital were enrolled. Demographics, co-morbidities, indication for the procedure, procedural details, and outcomes were recorded. The primary aim was to evaluate midterm clinical outcomes, including branch primary patency and reintervention rates. The secondary aim was to compare outcomes based on LCCA branch orientation. RESULTS: Some patients were treated. Indications were degenerative (49%) or post-dissection (51%) arch aneurysms. Percutaneous approach was more common in the retrograde group (74% versus 24%, P < 0.001), which also had shorter operative times (160.5 versus 234.0 min, P < 0.001). Thirty-day stroke occurred in five patients (7%; 3% retrograde versus 11% antegrade, P = 0.361). Thirty-day mortality was 3% (3% versus 3%, P = 1) and postoperative heart failure developed in three patients (6% versus 3%, P = 0.599). Median follow-up was 35.8 months (i.q.r. 17.5-62.6 months). During follow-up, 8 patients died (11%) and 14 (19%) required reintervention. Branch primary patency was 100%. CONCLUSIONS: Endovascular aortic arch repair with a triple-branch device is associated with favourable early outcomes. A retrograde LCCA branch orientation was associated with shorter operative times, and an increased potential for a totally percutaneous approach. Multicentre studies are required to confirm these findings and evaluate long-term outcomes.

Critical review of an instrument from the House of the Roman Surgeon in Rimini.

Daoulas T, Mollard-Tanguy H, Courtil JC … +3 more , Lefèvre C, Savéan J, Pardon-Labonnelie M

Br J Surg · 2025 Nov · PMID 41206575 · Publisher ↗

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Wearable-supported self-managed rehabilitation after breast cancer surgery: aligning with the NHS 10-year health plan.

Latif A, Joshi M, Darzi A … +1 more , Leff DR

Br J Surg · 2025 Nov · PMID 41206574 · Publisher ↗

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Bridging the gap: exposing the hidden challenges towards adoption of artificial intelligence in surgery.

Manzano Rodriguez A, Snoek CGM, Schijven MP

Br J Surg · 2025 Nov · PMID 41206573 · Publisher ↗

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Surgical site infection.

Sánchez-Rodríguez M, Pastor C, Tejedor P

Br J Surg · 2025 Oct · PMID 41159951 · Publisher ↗

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Ten steps towards better perioperative intravenous fluid therapy.

Ess M, Lobo DN

Br J Surg · 2025 Oct · PMID 41159950 · Publisher ↗

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A novel melting temperature mapping method may improve the prediction of postoperative intra-abdominal infection after pancreatoduodenectomy.

Tanaka H, Fukasawa M, Kimura N … +12 more , Mori K, Matsui K, Itoh A, Hirano K, Watanabe T, Shirai Y, Nagaoka K, Shibuya K, Yoshioka I, Yamamoto Y, Niimi H, Fujii T

Br J Surg · 2025 Oct · PMID 41134206 · Full text

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Endoscopic retrograde appendicitis therapy versus laparoscopic appendectomy for uncomplicated acute appendicitis with appendicoliths: a multicentre retrospective cohort study.

Liu ZH, Zhou XR, Liao S … +7 more , Liu TY, Liu Y, Wang YZ, Qiao M, Li XQ, Ding YB, Liu WH

Br J Surg · 2025 Oct · PMID 41092406 · Publisher ↗

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Blood loss during pancreatic surgery: defining minimal clinically significant difference using standardized estimation.

Perri G, Ribeiro T, Maekawa A … +8 more , Dall'Olio T, Romandini E, Ghorbani P, Cillo U, Fong ZV, Marchegiani G, Sparrelid E, Hallet J

Br J Surg · 2025 Oct · PMID 41092405 · Publisher ↗

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International Federation for the Surgery and Other Therapies for Obesity (IFSO) global consensus recommendations for optimizing outcomes after sleeve gastrectomy.

Cohen RV, Kermansaravi M, Levinson R … +6 more , Lakdawala M, Parmar C, Seki Y, Prager G, Salminen P, members of the Global Consensus Recommendations for Optimizing Outcomes after Sleeve Gastrectomy

Br J Surg · 2025 Oct · PMID 41092404 · Publisher ↗

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'Play to the conditions': optimizing the operating theatre environment through lessons from elite performance domains.

Boyle CP, Crichton J, Sgrò A … +4 more , Michael SH, Wigmore SJ, Skipworth RJE, Yule S

Br J Surg · 2025 Oct · PMID 41092403 · Publisher ↗

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Predictors of long-term survival for patients with pancreatic neuroendocrine neoplasm in FinPanNET: nationwide biobank study with histopathological re-evaluation.

Majala S, Elonen L, Kaprio T … +28 more , Vesterinen T, Kauhanen S, Sammalkorpi H, Parviainen H, Schalin-Jäntti C, Schildt J, Laukkarinen J, Ahola R, Nieminen L, Rinta-Kiikka I, Ronkainen J, Sipilä K, Nortunen M, Karjula H, Huhta H, Pohjanen VM, Mäkinen M, Söderström M, Kemppainen J, Mrena J, Kuopio T, Koivula AS, Rantanen T, Pulkkinen J, Sironen R, Haglund C, Arola J, Seppänen H

Br J Surg · 2025 Oct · PMID 41082591 · Publisher ↗

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Patient characteristics and perioperative outcomes in the Bypass Equipoise Sleeve Trial (BEST) compared to general metabolic bariatric practice in Sweden.

Hedberg S, Stenberg E, Österberg J … +8 more , Andersson E, Peltonen M, Näslund E, Neovius M, Thorell A, Olbers T, Ottosson J, BEST Study Group

Br J Surg · 2025 Oct · PMID 41070781 · Full text

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