Revista Medico-chirurgicala A Societatii De Medici Si Naturalisti Din Iasi[JOURNAL]
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200 papers
The Impact of Socioeconomic Status and Nutritional Biochemical Markers on Quality of Life of Chronic Dialysis Patients?
Nitoi LC, Aspazia Stefan A, Ionita C … +2 more , Andrei C, Vulpoi C
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 30137952
AIM: This cross-sectional study aimed to determine the relationship between socio-economic status and laboratory values with mental and physical components of QoL (quality of life) in chronic dialysis patients. MATERIAL...
AIM: This cross-sectional study aimed to determine the relationship between socio-economic status and laboratory values with mental and physical components of QoL (quality of life) in chronic dialysis patients. MATERIAL AND METHODS: 254 patients were included in the study and divided into two groups: 243 hemodialysis (HD) patients and 11 peritoneal dialysis (PD) patients. QoL was measured by the Short Form 36(SF-36). Scores for all dimensions are expressed on a 0-100 scale. Higher score indicates better health status. Two more questions related to monthly food expenditure and the presence/or lack of family support were added. Laboratory investigations included the following nutritional parameters: serum albumin and creatinine. RESULTS: Our study results showed that compared to PD group in HD patients QoL was compromised in all SF-36 subscale except physical functioning, role limitations due to physical functioning and role limitations due to emotional functioning. Also, the presence of supportive family members/ caregivers showed a significant improvement of all QoL scores. HD patients who spend at least 90 euros monthly on groceries/food had higher values of SF-36 items. Better QoL is associated with high pre-dialysis serum creatinine and serum albumin levels. CONCLUSIONS: Future work should incorporate larger and more balanced sample sizes and patient recruitment from multiple dialysis centers to truly capture the variability in patient characteristics.
Complementary Multidisciplinary Elder Abuse Service in A Geriatric Clinic.
Gavrilovici O, Alexa ID, Dronic A … +3 more , Sandu IA, Pancu A, Pîslaru AI
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 30137951
AIM: To describe a pilot, innovative intervention project combining the adoption and adaptation for hospital use of a screening instrument designed for use in primary health care settings in Canada (and translated into 6...
AIM: To describe a pilot, innovative intervention project combining the adoption and adaptation for hospital use of a screening instrument designed for use in primary health care settings in Canada (and translated into 6 other languages) and a dialogical narrative therapeutic approach. The development of a complementary multidisciplinary elder abuse service (CMEAS) in a private-public partnership. MATERIAL AND METHODS: Between June 2015 – March 2016 elderly hospitalized in Iasi town, Geriatric Clinic and suspected of being abused had the benefit of a complementary multidisciplinary elder abuse service (CMEAS) after being screened for abuse, neglect or abandonment experiences. RESULTS: A total of 450 patients admitted to the Geriatric Clinic were invited for the study and 152 raised suspicion of abuse experiences and were screened with EASI. Of these patients, 132 where found positive and were invited to participate in CMEAS. CONCLUSIONS: Such a multidisciplinary service requires the collaboration between the geriatric team (medical service), psychologist, social worker, legal advisor, and psychiatrist, referral of cases to relevant public and private community services and their monitoring after hospital discharge throughout project duration.
Can Bioelectrical Impedance Analysis Help Us in Managing, Easy and Faster Our Patients' Health Problems?
Stratulat IS
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 30137926
Bioelectrical impedance principle it is a new way of detecting abnormal cellular response. Wegamed devices use this method to discover in a holistic manner a view of the man in all dimensions, body, emotions and intellec...
Bioelectrical impedance principle it is a new way of detecting abnormal cellular response. Wegamed devices use this method to discover in a holistic manner a view of the man in all dimensions, body, emotions and intellect, and correlate’s the treatment with the characteristics of the individual at all these levels. The aim of the study was to see if using alternative medicine methods can we evaluate correct and noninvasive the patients. Material and methods: A retrospective study was conducted to investigate the correlations between the clinical and paraclinically diagnoses and the diagnoses offered by the Wegamed devices. The study includes 440 patients who referred to our clinic between January 2013 and January 2016, who were thoroughly examined through evidence-based medicine methods and then undergo the Test expert plus analyze. Results: This retrospective study showed a concordance for some pathologies and diagnostics. The concordance was 100% for acute or oncological pathologies and for other pathologies, mostly chronic, degenerative; the most important is the doctor, who must interpret and correlate, based on his/her experience. Conclusion: The classical diagnostic methods can provide accuracy, but a personalized treatment requires viewing the man in all dimensions and specific correlations with the characteristics of the individual.
Ethnobotanical and Cannabis Drug Use: A Step Between Danger and Pleasure.
Grigoraşi G, Cimpoeşu DC, Popa V … +5 more , Nedelea P, Popa OT, Ciumanghel AI, Drochioi S, Corlade-Andrei M
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 30137785
AIM: The study aimed to identify the risk factors and the particularities of ethnobotanicals and cannabis users who needed medical care in the Emergency Department of the „Sf. Spiridon” County Hospital. MATERIAL AND METH...
AIM: The study aimed to identify the risk factors and the particularities of ethnobotanicals and cannabis users who needed medical care in the Emergency Department of the „Sf. Spiridon” County Hospital. MATERIAL AND METHODS: Retrospective study conducted over a period of 18 months (January 1, 2015- June 30, 2016). This study included all patients who presented to the E.D. after drug (cannabis and ethnobotanicals) consumption. The variables studied for creating the consumer profile were sex, age, social background, method of consumption, clinical and laboratory changes. RESULTS AND DISCUSSION: The study included 153 patients brought to hospital by ambulance (71.89%) for cannabis or ethnobotanical poisoning. Most patients were males (92.15%) from urban areas (75.97%), aged between 18 and 24 years (52.28%). At the time of admission to ED 96.07% of them needed medical care for consumption of ethnobotanicals through various methods and only 3.92% were brought to hospital for cannabis or marijuana use. For 61.70% of patients, curiosity was the reason behind their addiction. Toxicology testing (qualitative urine analysis) was useful in identifying the presence of tetrahydrocannabinol(THC) or a combination of THC and barbiturates, benzodiazepines, opioids in 26.53% of ethnobotanical and 66.67% of cannabis users. CONCLUSIONS: In Romania, the most commonly used drugs are cannabis followed by ethnobotanical products. For a while, ethnobotanical products were falsely considered as risk-free, but they contain dangerous substances with devastating effects, which, unless treatment is initiated immediately, can lead to death.
The Link Between Quality of Life and Economic Issues in Ankylosing Spondylitis.
Rezus E, Cardoneanu A, Macovei L … +2 more , Stamate G, Burlui A
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 30137764
Ankylosing spondylitis (AS) is an inflammatory rheumatic disorder which mainly involves the axial skeleton. The most important clinical features are: inflammatory back pain and peripheral joint involvement, but extra-art...
Ankylosing spondylitis (AS) is an inflammatory rheumatic disorder which mainly involves the axial skeleton. The most important clinical features are: inflammatory back pain and peripheral joint involvement, but extra-articular manifestations that occur most often in the eyes, heart and lungs may also be present. Joint stiffness, pain and a progressive loss of spinal mobility can lead to severe functional limitations with subsequent negative impact on patients' quality of life. These symptoms can interfere not only with physical health, but also with social life and psychological wellbeing. Many studies took into consideration these aspects and tried to analyze the relationship between disease activity, functional impairment, work ability, interpersonal relationships and total costs of this debilitating disease. After many years of studying, the authors concluded that AS has a socio-economic impact on patients, society and healthcare system.
Atherosclerosis in the Young Adult: Fewer Hypotheses, More Facts.
Dima-Cozma C
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 30137762
Several studies have reported early atherosclerotic changes in arterial wall of young adults, although they usually become symptomatic after age 40 years. Initially, some sporadic and limited data were available to docum...
Several studies have reported early atherosclerotic changes in arterial wall of young adults, although they usually become symptomatic after age 40 years. Initially, some sporadic and limited data were available to document the atherosclerotic lesions in young adults; early subclinical assessment were later possible using accurate ultrasound and other imaging techniques. Our aim was to a review of eloquent studies proving different type of atherosclerotic lesion in the young adult. Long-term follow-up and further analysis of this population demonstrated important relationship with traditional and some non-traditional, risk factors. The data comprised in the reviewed studies are arguments in favor of a more refined atherosclerotic risk assessment and appropriate preventive strategy in young adult.
Ethiopatogenic Hypotheses in Lichen Planus.
Brănişteanu DE, Pintilie A, Andreş LE … +4 more , Dimitriu A, Oanţă A, Stoleriu G, Brănişteanu DC
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 30137759
Lichen planus is a mucocutaneous inflammatory dermatosis characterized by a papular rash; the disease is self-limited, has several clinical subtypes and follows a chronic or subacute clinical course. This article present...
Lichen planus is a mucocutaneous inflammatory dermatosis characterized by a papular rash; the disease is self-limited, has several clinical subtypes and follows a chronic or subacute clinical course. This article presents some etiological hypotheses: stress, genetic predisposition, systemic diseases, viral infections, materials used in dentistry. Also, medicines or contact allergens can cause lichenoid reactions, which are the main differential diagnosis. Autoimmune hypothesis can be supported by the association with other autoimmune diseases, such as ulcerative colitis, alopecia areata, vitiligo, dermatomyositis, morphea, lichen sclerosus, myasthenia gravis. This disease seems to be mediated through an antigenic mechanism of cytotoxic T lymphocyte activation, and production of proinflammatory cytokines, cascade of events that causes apoptosis of basal keratinocytes. A good understanding of the pathogenesis, clinical presentation and early diagnosis of lichen planus is critical in determining the appropriate therapeutic management. This present article aims to present and discuss the various etiopathogenetic concepts of lichen planus.
Polycystic Ovary Syndrome, A Complex Entity Involving Reproductive and Metabolic Impairments: A Systematic Review.
Amihăesei IC, Chelaru L, Lăcrămioara Zamfir C
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 30137754
We attempt to synthesize main data in what concerns pathogenesis, signs and symptoms, diagnosis and management of polycystic ovary syndrome PCOS. The issue was the systematization of main data regarding different feature...
We attempt to synthesize main data in what concerns pathogenesis, signs and symptoms, diagnosis and management of polycystic ovary syndrome PCOS. The issue was the systematization of main data regarding different features of PCOS and stressing its peculiar association with characteristics of metabolic syndrome, main diagnostic criteria and most important therapeutic options, finally contouring an updated general picture of PCOS. We pointed also on associated morbidities, such as endometrial cancer, insulin resistance and need for individualized therapy, including changing in lifestyle, especially weight loss.
Topicalities in the Sudden Unexpected Death Syndrome in Infants.
Rugină AL, Frăsinariu O, Streangă V … +3 more , Sârbu I, Cărăuleanu A, Rugină VG
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 30137751
Sudden Infant Death Syndrome (SIDS) represents the third cause in postnatal mortality. The pathogenesis is multifactorial. SIDS victims can present sign of preexisting chronic asphyxia, persistent increase in dendritic s...
Sudden Infant Death Syndrome (SIDS) represents the third cause in postnatal mortality. The pathogenesis is multifactorial. SIDS victims can present sign of preexisting chronic asphyxia, persistent increase in dendritic spine and delayed maturation of synapses in medullary respiratory centers, if a decreased reactivity of 5 hydroxytryptamine 1A (5-HT1A) and 5-HT2A in the dorsal nucleus of the vagus, solitary nucleus and ventrolateral medulla. SIDS is an exclusion diagnosis, so that inexplicable SIDS is the accepted term. The objective of this report is to present current data about the pathogenesis oh this syndrome and the medico-legal measures applied in preventive and curative aim. The “face-up” sleeping position has cut in half the SIDS frequency. In conclusion, the infant sleep studies represent an important line for the future research to provide sufficient explanation of the sudden death in these infants.
Mucosal Healing In Ulcerative Colitis-The Fountain of Youth?
Cijevschi Prelipcean C, Mihai C
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 30137701
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LOW LEVELS OF SERUM CYANOCOBALAMIN IN A METFORMIN-TREATED PATIENT. CASE REPORT AND COMPARISON WITH LITERATURE DATA.
Strugaru AM, Botnariu G, Tuchiluş C … +4 more , Anisie E, Agoroaei L, Grigoriu IC, Butnaru E
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 27483736
Metformin is a widely used oral antidiabetic biguanide compound. According to the literature, metformin may lower the serum cyanocobalamin levels. We present the case of a 71-old-male treated with metformin for 15 years....
Metformin is a widely used oral antidiabetic biguanide compound. According to the literature, metformin may lower the serum cyanocobalamin levels. We present the case of a 71-old-male treated with metformin for 15 years. When presenting to a periodic checkup, low serum cyanocobalamin levels where found. Laboratory tests showed levels below normal range for hemoglobin (12.7 g/dL) and hematocrit (37.8%). After patient reevaluation, a change in antidiabetic treatment will be considered if metformin will be found the cause of low serum cyanocobalamin levels. Other cases reported in the literature support this hypothesis, justifying the study of the influence of metformin therapy on serum vitamin B12 levels in patients diagnosed with diabetes. The influence of patient age, metformin dosage, duration of treatment and time since diabetes diagnosis on serum levels of vitamin B12 also need to be determined.
CATECHINS PROFILE, CAFFEINE CONTENT AND ANTIOXIDANT ACTIVITY OF CAMELLIA SINENSIS TEAS COMMERCIALIZED IN ROMANIA.
Luca VS, Stan AM, Trifan A … +2 more , Miron A, Aprotosoaie AC
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 27483735
AIM: Catechins profile, caffeine content and antioxidant activity of different green tea and white tea samples commercialized on the Romanian market were investigated. MATERIAL AND METHODS: Five green tea samples and fiv...
AIM: Catechins profile, caffeine content and antioxidant activity of different green tea and white tea samples commercialized on the Romanian market were investigated. MATERIAL AND METHODS: Five green tea samples and five white tea samples commonly available on the Romanian market were processed by infusion and the lyophilisates of infusions were analyzed. Total phenolic content was determined using the Folin-Ciocalteu method. Catechins and caffeine profile was analyzed by RP-HPLC-DAD (Agilent Eclipse XDB-C18 column, binary mobile phase (A) 3% acetic acid and (B) methanol). In vitro antioxidant activity was assessed by free radical scavenging and ferrous ion chelating assays. RESULTS AND DISCUSSIONS: Total phenolic content ranged between 44.73 +/- 0.63 and 63.57 +/- 0.45 GAE% in green tea samples and between 9.69 +/- 0.90 and 52.99 +/- 0.45 GAE% in white tea samples. RP-HPLC-DAD analysis allowed the identification of epigallocatechin gallate (45.18-118.58 mg/g lyophilisate) and caffeine (47.79-108.07 mg/g lyophilisate) in all tea samples; epicatechin was detected in all samples (5.04-31.04 mg/g lyophilisate) except for two white teas infusions. Green tea samples scavenged DPPH radical and chelated ferrous ion with EC50=9.68 +/- 0.02-16.11 +/- 0.02 microg/mL and 10.91 +/- 0.04-18.65 +/- 0.03 microg/mL, respectively. For white teas, EC50 values varied between 9.50 +/- 0.02-20.95 +/- 0.02 microg/mL in DPPH assay and 12.49 +/- 0.03-20.32 +/- 0.07 microg/mL in ferrous ion chelating assay. CONCLUSIONS: This study showed a large variability in the content of catechins and caffeine and in the antioxidant capacity of both green and white tea samples.
IN VITRO MEASUREMENT OF TOTAL ANTIOXIDANT CAPACITY OF CRATAEGUS MACRACANTHA LODD LEAVES.
Miftode AM, Stefanache A, Spac AF … +3 more , Miftode RF, Miron A, Dorneanu V
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 27483734
UNLABELLED: Crataegus macracantha Lodd, family Rosaceae, is a very rare species in Europe, and unlike Crataegus monogyna is less investigated for pharmacologic activity. AIM: To analyze the ability of the lyophilisate of...
UNLABELLED: Crataegus macracantha Lodd, family Rosaceae, is a very rare species in Europe, and unlike Crataegus monogyna is less investigated for pharmacologic activity. AIM: To analyze the ability of the lyophilisate of extract obtained from leaves of Crataegus macracantha Lodd (single plant at the Iaşi Botanical Garden) to capture free radicals in vitro. MATERIAL AND METHODS: The lyophilisate obtained in Department of Pharmacognosy, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy Iaşi. The decreased absorbance of chromophore chlorpromazine radical cation in the presence of the lyophilized solutions was studied spectrophotometrically. The indicator radical cation, obtained by oxidation of chlorpromazine by potassium persulfate, has the maximum absorbance at 525 nm. Ascorbic acid was used as a standard antioxidant. RESULTS: The absorbance of radical solution was determined after the addition of a certain amount of lyophilisate at different time intervals. The antioxidant activity was calculated using the calibration curve obtained by plotting the variation in radical solution absorbance depending on ascorbic acid concentration. For each ascorbic acid concentration the area under the curve was calculated from plotting the percentage inhibition of the absorbance at two pre-established time intervals. CONCLUSIONS: The results confirm the antioxidant activity of the leaves of Crataegus Macracantha Lodd and by optimizing the proposed analytical methods the antiradical activity can be quickly evaluated with minimal reagent consumption.
INFLUENCE OF CARBOXYMETHYLCELLULOSE SODIUM AND LUTROL ON THE SWELLING INDEX AND DISINTEGRATION TIME OF BIOMUCOADHESIVE TABLETS WITH MICONAZOLE NITRATE.
Birsan M, Scutariu MM, Cojocaru I
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 27483733
UNLABELLED: PURPOSE. To develop original pharmaceutical formulation with miconazole nitrate, biomucoadhesive tablets, used in antifungal medication. MATERIAL AND METHODS: The oral biomucoadhesive tablets with miconazole...
UNLABELLED: PURPOSE. To develop original pharmaceutical formulation with miconazole nitrate, biomucoadhesive tablets, used in antifungal medication. MATERIAL AND METHODS: The oral biomucoadhesive tablets with miconazole nitrate were developed by direct compression of the excipient mixture: carboxymethylcellulose sodium and lutrol 6000, excipients used for bioadhesivity, mannitol as a sugar substitute and aerosil as a lubricant. The main goal of the study is to determine the disintegration time and the swelling index of biomucoadhesive tablets with miconazole nitrate in order to estimate the time of contact with mucosa, respectively the prolongation of drug substance release. RESULTS: The swelling index was calculated depending on time in all the 5 formulations that included the carboxymethylcellulose sodium and Lutrol 6000 as matrix-forming, and the studied were time and association ratio between polymers. CONCLUSIONS: Analysing the results, we noticed that out of the four excipients we used, carboxymethylcellulose sodium had the higher influence on the swelling index and disintegration time.
EVALUATION OF ANTIOXIDANT ACTIVITY OF SOME IMINES DERIVATIVES OF L-ARGININE.
Iacob AT, Drăgan M, Constantin S … +5 more , Lupaşcu F, Confederat L, Buron F, Routier S, Profire L
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 27483732
UNLABELLED: L-Arginine is an a-amino acid which plays important roles in different diseases or processes, such as Alzheimer disease, inflammatory process, healing and tissue regeneration and it also could be useful as an...
UNLABELLED: L-Arginine is an a-amino acid which plays important roles in different diseases or processes, such as Alzheimer disease, inflammatory process, healing and tissue regeneration and it also could be useful as an anti-atherosclerotic agent. AIM: Considering the large amount of studies on the beneficial effects of different antioxidants, this paper is focused on the evaluation of the antioxidant potential of some imine derivatives, synthesized by the authors and described in a previous article. MATERIAL AND METHODS: The evaluation of the antioxidant power was performed using phosphomolydenum-reducing antioxidant power (PRAP) and ferric reducing antioxidant power (FRAP) assays, tests described in the literature and which are used with some minor modifications. RESULTS: It was found that most of the imine derivatives are more active than the L-Arginine in the PPAP and FRAP assays. The most active derivative was the compound obtained by condensation of L-arginine with 2,3-dihydroxybenzaldehyde (2k) and 2-nitrobenzaldehyde (2g). CONCLUSIONS: Following the described protocol, some imine derivatives of L-arginine were evaluated in terms of antioxidant potential using in vitro methods. The most favorable influence was obtained by the aromatic substitution with nitro and hydroxyl, the corresponding derivatives being the most active derivatives compared to L-arginine.
EVALUATION OF THE SYNTHESIS AND STRUCTURE OF NEW AZETIDIN-2-ONES OF FERULIC ACID.
Stan CD, Drăgan M, Pânzariu A … +1 more , Profire L
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 27483731
AIM: To synthesize some new azetidin-2-ones of ferulic acid and to evaluate them from physicochemical and spectral point of view. MATERIAL AND METHODS: The synthesis was carried out in several steps: (i) obtaining the fe...
AIM: To synthesize some new azetidin-2-ones of ferulic acid and to evaluate them from physicochemical and spectral point of view. MATERIAL AND METHODS: The synthesis was carried out in several steps: (i) obtaining the ferulic acid chloride; (ii) obtaining the ferulic acid hydrazide with hydrazine hydrate (98%); (iii) condensation of ferulic acid hydrazide with different benzaldehydes (2-hydroxy-/2-nitro-/4-chloro-/4- fluoro-/4-bromo-benzaldehyde) in order to obtain the corresponding hydrazones; (iv) cy- clization of ferulic acid hydrazones with chloroacethyl chloride in freshly distilled toluene medium and in the presence of triethylamine, resulting in the corresponding azetidin-2-ones. RESULTS: Six new azetidin-2-ones of ferulic acid were synthesized. They were characterized in terms of their physicochemical properties and their structure was confirmed by IR and 1H-NMR spectroscopy. CONCLUSIONS: Six new azetidin-2-ones of ferulic acid were synthesized, physicochemically characterized and validated spectrally. A
ALCOHOL CONSUMPTION WITH FAMILY PATTERN RELATED TO STRONG PERSONALITIES: A CASE-CONTROL STUDY IN MARRIED ROMANIAN STUDENTS.
Petrescu C
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 27483730
UNLABELLED: In the study conducted the aim was to investigate strong personalities (SP) related to alcohol consumption in married students from Romania. MATERIAL OF STUDY: Consisted in 2 samples: a case-sample (23 alcoho...
UNLABELLED: In the study conducted the aim was to investigate strong personalities (SP) related to alcohol consumption in married students from Romania. MATERIAL OF STUDY: Consisted in 2 samples: a case-sample (23 alcohol consumer students with a family pattern of weekly consumption, 47.8% male and 52.2% female, aged 21-29 years) and a control-sample (42 no-alcohol consumer students without a family pattern of consumption, 26.2% male and 73.8% female, aged 21-29 years), selected from a sample of 176 married students. METHOD: An observational inquiry (case-control) consisted in applying 2 questionnaires: Health Questionnaire (60 items, 7: Q43-Q49 -alcohol consumption) and Strong Personalities Questionnaire (88 items, alpha-Crohnbach index-0.823). Statistical analysis was performed by the aid of SPSS 20 Program. RESULTS: For alcohol consumer students with weekly pattern of consumption the main reason of alcohol consumption was curiosity (60.9%) and the most frequent consumed alcohol was beer (38.6%, 500-3000 ml/week). Personalities' profiles revealed V-hyperthymic, III-hyperperseverant and X-emotive strong personalities (SP) as being symptomatic (over 50% symptomatic level-SL) for both samples, with a difference (control-case) for X-emotive SP (71.7% students--57.1% students, respectively). I-demonstrative, VII-cyclothymic and IV-unruly SP presented a difference between case (symptomatic: 61.8%; 61.8% and 61.8% students, respectively) and control (symptomatic: 36.8%; 37.5% and 45% students, respectively) samples. A statistically significant difference case-control samples was demonstrated for I-Demonstrative (item S29: chi square chi2 = 10.65; Sig.0.002; gamma correlation gamma=0.73; Sig.0.002) and for X-emotive (item S25: chi2 = 8.76; gamma = -0.66; Sig.0.003) SP. In conclusion, a relation SP-alcohol consumption in married students is suggested.
EPIDEMIOLOGIC RESEARCH REGARDING THE IMPACT OF RISK FACTORS ON HEALTH-RELEATED QUALITY OF LIFE IN CANCER PATIENTS.
Manafu E, Nemet C, Jarit I
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 27483729
AIM: To assess the health-related quality of life in cancer patients and the relative and attributable risks for the degree of dissatisfaction related to intrinsic and extrinsic factors. MATERIAL AND METHODS: Our researc...
AIM: To assess the health-related quality of life in cancer patients and the relative and attributable risks for the degree of dissatisfaction related to intrinsic and extrinsic factors. MATERIAL AND METHODS: Our research included 128 cancer patients treated at the Surgical Clinic II of the Iasi Regional Cancer Institute between December 2014 and June 2015. Thus, data were collected by using an inquiry sheet derived from the SF-36 questionnaire, which included closed and open questions about the quality of life, socioemographic data and such risk factors as smoking, alcohol use, related diseases and risk behaviours. Results: The patient sample had a mean age of 60.85 years, 51.6% of them lived in urban areas, were high school graduates, and of low economic status. DISCUSSION: As to the behavioural risk factors we found that over 80% of the patients were non-smokers, did not use alcohol, and were normal weighted. Pain was experienced by 70.7% of the cancer patients and depression affected 74% of the study cases. Patients were asked to self-assess their own health status on a scale of 0 (worst) to 100 (the best health status). CONCLUSIONS: Our study showed a poor health status (mean score 65) in the study cancer patients. The relative and attributable risks for the degree of dissatisfaction related to intrinsic and extrinsic factors were calculated and ranked factors in decreasing order: smoking, depression, pain, alcohol use, male gender, obesity, low income. We found that prolonged'suffering affects the psyche and causes depression and that the patients of low financial status, most of them living in villages, have difficulty in accessing medical care. The obtained data about the quality of life in relation with risk factors are in agreement with the data in the literature.
STRESS IN PEDIATRIC PATIENTS--THE EFFECT OF PROLONGED HOSPITALIZATION.
Mîndru DE, Stănescu RS, Mioara CM … +5 more , Duceac LD, Rugina A, Temneanu OR, Ungureanu M, Florescu L
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 27483728
Long-term hospitalization emotionally impacts any patient, especially children, and is defined as a long period of time during which the patient is hospitalized and experiences isolation from his or her family, friends a...
Long-term hospitalization emotionally impacts any patient, especially children, and is defined as a long period of time during which the patient is hospitalized and experiences isolation from his or her family, friends and home. Stressful situations trigger a nonspecific response that involves multiple physiological mechanisms. Currently, because of the complexity of these mechanisms, there are no laboratory markers that allow the quantification of the stress intensity felt by the patient. Laboratory determinations currently used in evaluating the response to stress are neuroendocrine, immunological and metabolic. The neuroendocrine system is the first to respond to stressful events. Stress stimulates the hypothalamus, leading to the release of CRH, which stimulates the pituitary gland to produce ACTH. Chronic stress directs the synthesis towards cortisol, which may lead to hypo secretion of the other adrenal steroid hormones. The hospital and the disease are stressors for children and caregivers, since stress can interfere with the normal development of young patients, affecting them in the long term. Admitting a child to hospital means interrupting his or her normal daily life and changing the environment that is familiar to him or her. Therefore, the involvement of the family doctor is very important, as many conditions can be solved by visiting his or her office and thus eliminating the need for hospitalization in a pediatric hospital. If, however, the nature of the condition requires that the child should be seen by a pediatrician, the period of hospitalization should not be much extended so as to prevent the appearance of other possible problems that might influence the child's state.
CONSIDERATIONS ON ANATOMY AND PHYSIOLOGY OF LYMPH VESSELS OF UPPER AERO DIGESTIVE ORGANS AND CERVICAL SATELLITE LYMPH NODE GROUP.
Ciupilan C, Stan CI
Rev Med Chir Soc Med Nat Iasi · 2016 · PMID 27483727
The almost constant local regional development of the cancers of upper aero digestive organs requires the same special attention to cervical lymph node metastases, as well as to the primary neoplastic burning point. The...
The almost constant local regional development of the cancers of upper aero digestive organs requires the same special attention to cervical lymph node metastases, as well as to the primary neoplastic burning point. The surgical therapy alone or associated has a mutilating, damaging character, resulting in loss of an organ and function, most of the times with social implications, involving physical distortions with aesthetic consequences, which make the reintegration of the individual into society questionable. The problem of cervical lymph node metastases is vast and complex, reason why we approached several anatomical and physiological aspects of lymph vessels of the aero digestive organs. Among the available elements during treatment, the headquarters of the tumour, its histologic degree, and its infiltrative nature, each of them significantly influences the possibility of developing metastases.
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