Ngozi Osueke A, Nwozichi C, Salako O
… +1 more, Omotunde Okesiji I
Oncol Nurs Forum
· 2026 Jan · PMID 41525455
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OBJECTIVES: To evaluate handgrip strength (HGS), functional capacity (FC), and quality of life (QOL) in adults with cancer, and to examine the associations among these variables to explore the potential utility of HGS as...OBJECTIVES: To evaluate handgrip strength (HGS), functional capacity (FC), and quality of life (QOL) in adults with cancer, and to examine the associations among these variables to explore the potential utility of HGS as an accessible indicator of functional status and well-being in oncology care. SAMPLE & SETTING: A consecutive sample of 269 adult patients with cancer at Lagos State University Teaching Hospital in Nigeria participated in the study. METHODS & VARIABLES: A descriptive cross-sectional study measured HGS using a digital hand dynamometer, FC via the FC Index Questionnaire, and QOL through the City of Hope QOL Instrument-Breast Cancer Patient Version adapted for use with all cancer types. Data analysis used descriptive and inferential statistics. RESULTS: Nearly half (49%) exhibited weak HGS, with only 14% showing strong HGS. A significant number (55%) experienced mild to moderate FC limitations, and the majority (81%) reported moderate to very low QOL. Statistically significant associations were found between HGS and FC, and between HGS and QOL. IMPLICATIONS FOR NURSING: Routine assessment of HGS should be incorporated into oncology nursing practice to facilitate early identification of functional decline, guide targeted rehabilitation interventions, and enhance patient-centered care aimed at improving QOL.
Yang GS, Graziano TA, Li A
… +5 more, Oppong AF, Cousin L, Lynch Kelly D, Starkweather A, Lyon DE
Oncol Nurs Forum
· 2026 Jan · PMID 41505724
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OBJECTIVES: To examine racial disparities in psychoneurological (PN) symptom severity and health-promoting behaviors among breast cancer survivors (BCS) over time. SAMPLE & SETTING: BCS (N = 74) were assessed at base...OBJECTIVES: To examine racial disparities in psychoneurological (PN) symptom severity and health-promoting behaviors among breast cancer survivors (BCS) over time. SAMPLE & SETTING: BCS (N = 74) were assessed at baseline; the chemotherapy midpoint; and six months, one year, and two years postchemotherapy. METHODS & VARIABLES: A secondary analysis of a longitudinal, prospective study was conducted using linear mixed-effects models to examine trajectories of PN symptoms and health-promoting lifestyle behaviors. RESULTS: Black BCS experienced greater pain, fatigue, and cognitive impairment. White BCS reported significant changes in anxiety, sleep disturbance, fatigue, neurocognition, and leisure-time exercise, with symptoms worsening at the chemotherapy midpoint and improving thereafter. Black BCS exhibited no significant changes across time points. IMPLICATIONS FOR NURSING: Culturally sensitive, tailored symptom management strategies and structural interventions are needed. Future research is warranted to identify the unique needs and preferences of Black BCS to improve their symptom experiences and encourage health-promoting lifestyle behaviors.
Oncol Nurs Forum
· 2026 Jan · PMID 41505723
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Preparation for older age allows us to withstand health challenges such as a cancer diagnosis or functional/cognitive decline. The same principle applies to nursing regarding professional reserve. We need a full fuel tan...Preparation for older age allows us to withstand health challenges such as a cancer diagnosis or functional/cognitive decline. The same principle applies to nursing regarding professional reserve. We need a full fuel tank to.
Oncol Nurs Forum
· 2025 Oct · PMID 41123402
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DNP-prepared nurses bring clinical expertise, clinical system-level thinking, and a focus on implementation science. PhD-prepared nurses contribute knowledge of research design, methodology, and data analysis. Together,...DNP-prepared nurses bring clinical expertise, clinical system-level thinking, and a focus on implementation science. PhD-prepared nurses contribute knowledge of research design, methodology, and data analysis. Together, they.
Oncol Nurs Forum
· 2025 Oct · PMID 41123401
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To commemorate the Oncology Nursing Society's 50th anniversary in 2025, throughout the year, we will be reprinting seminal editorials written by former editors of the Oncology Nursing Forum and the Clinical Journal of On...To commemorate the Oncology Nursing Society's 50th anniversary in 2025, throughout the year, we will be reprinting seminal editorials written by former editors of the Oncology Nursing Forum and the Clinical Journal of Oncol.
Xu Y, Wang J, Zhang Y
… +5 more, Guo Z, Zhang W, Zhang S, Shi W, Ma W
Oncol Nurs Forum
· 2025 Oct · PMID 41123400
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OBJECTIVES: To assess the occurrence of oral mucositis in Chinese patients with cancer undergoing treatment and analyze its influencing factors. SAMPLE & SETTING: From November 2023 to March 2024, a survey of 208 pat...OBJECTIVES: To assess the occurrence of oral mucositis in Chinese patients with cancer undergoing treatment and analyze its influencing factors. SAMPLE & SETTING: From November 2023 to March 2024, a survey of 208 patients with cancer was conducted. METHODS & VARIABLES: Data were collected through survey questionnaires and salivary pH testing. Demographic characteristics were analyzed using descriptive statistics. The Mann-Whitney U test was used to compare mucositis occurrence, and ordered logistic regression was used to identify predictive factors. RESULTS: Among 208 surveyed patients, 56 (27%) experienced oral mucositis, with severity grades distributed as follows: grade 1 (n = 37, 18%), grade 2 (n = 12, 6%), and grade 3 (n = 7, 3%). Salivary pH level, dry mouth, mouth rinsing, and primary disease were identified as key factors. IMPLICATIONS FOR NURSING: Chinese patients with cancer have a high occurrence of oral mucositis. Lower salivary pH levels and higher dry mouth scores increase the risk. Oncology nurses can prioritize early preventive strategies, salivary pH testing and xerostomia assessment, and targeted hygiene guidance. A risk-stratified prevention model can be implemented to enable precision management of oral mucositis.
Wu W, Li A, Graziano TA
… +6 more, Salner AL, Chen MH, Singh V, Judge MP, Cong X, Xu W
Oncol Nurs Forum
· 2025 Oct · PMID 41123399
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OBJECTIVES: To investigate the mediating effect of self-efficacy (SE) on the relationships among patient-provider partnership (PPP), pain, and quality of life (QOL) in individuals with cancer. SAMPLE & SETTING: Indiv...OBJECTIVES: To investigate the mediating effect of self-efficacy (SE) on the relationships among patient-provider partnership (PPP), pain, and quality of life (QOL) in individuals with cancer. SAMPLE & SETTING: Individuals with cancer were recruited online through cancer organizations and social media support groups in 2023. METHODS & VARIABLES: This cross-sectional survey collected data on demographic/clinical characteristics, cancer pain outcomes, PPP, SE for cancer pain management, and QOL. Mediation analyses assessed the role of SE in the relationships among PPP, pain, and QOL. RESULTS: Most participants were female, White, and aged 18-60 years. SE mediated the relationships between PPP and pain severity, pain interference, QOL function, and QOL symptoms. Greater PPP was associated with higher SE. IMPLICATIONS FOR NURSING: A supportive PPP is essential for improving pain outcomes and QOL in individuals with cancer by strengthening their SE.
Oncol Nurs Forum
· 2025 Oct · PMID 41123398
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OBJECTIVES: To assess whether the use of patient-reported outcomes (PROs) is associated with patient empowerment (PE) in cancer survivors in early survivorship. SAMPLE & SETTING: A convenience sample of 83 adult canc...OBJECTIVES: To assess whether the use of patient-reported outcomes (PROs) is associated with patient empowerment (PE) in cancer survivors in early survivorship. SAMPLE & SETTING: A convenience sample of 83 adult cancer survivors participated in a quantitative repeated-measures study at a community-based cancer center, and 33 participants who received chemotherapy as the last treatment modality of their primary cancer treatment completed a questionnaire immediately following treatment and at three months. METHODS & VARIABLES: Participants were recruited from the medical oncology clinic by oncology nurse research assistants and completed an electronic or paper survey composed of three instruments. RESULTS: A significant relationship was found between PE and self-efficacy, and a significant negative correlation was observed between self-efficacy and symptoms. PRO self-efficacy predicted PE following chemotherapy treatment. PE decreased at three months post-treatment. IMPLICATIONS FOR NURSING: Clinician-driven assessment is less sustainable in survivorship care. The use of PROs for symptoms and self-efficacy is related to PE. A qualitative study for conceptual clarification of PE in cancer survivors is needed. Oncology nurses are key to envisioning how to implement survivor-reported symptom assessment that builds empowerment.
Yang Y, Orchard TS, Winschel TR
… +7 more, Weinhold K, Jimmy J, Aase D, Schnell PM, Williams N, Lustberg MB, Gorka S
Oncol Nurs Forum
· 2025 Oct · PMID 41123397
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OBJECTIVES: To explore the relationship between intolerance of uncertainty (IU) and executive function (EF) in individuals with breast cancer. SAMPLE & SETTING: 21 postmenopausal women aged 45-75 years with stage I-I...OBJECTIVES: To explore the relationship between intolerance of uncertainty (IU) and executive function (EF) in individuals with breast cancer. SAMPLE & SETTING: 21 postmenopausal women aged 45-75 years with stage I-III breast cancer who completed chemotherapy 3-12 months before enrollment were included. METHODS & VARIABLES: In this pilot cross-sectional study, participants completed a task to probe neural responses to unpredictable threats, and anterior insula activation indicated objective IU. EF was measured by a neuropsychological test. Other self-reported measures were used to assess anxiety and fatigue. RESULTS: Results indicated that individuals with high objective IU demonstrated lower EF. No main effect of subjective IU on EF was found, and no mediation effect of anxiety on the relationship between IU and EF was found. IMPLICATIONS FOR NURSING: Healthcare providers need to consider IU when planning and providing survivorship education. Further research is needed to enhance the understanding of the role of IU on EF problems among individuals with breast cancer.
Alananzeh I, Green H, Sharifnia AM
… +2 more, Mofrad SA, Fernandez R
Oncol Nurs Forum
· 2025 Oct · PMID 41123396
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PROBLEM IDENTIFICATION: Hematopoietic stem cell transplantation has significant psychosocial impacts on pediatric sibling donors, including emotional distress, guilt, and anxiety. The aim of this qualitative review is to...PROBLEM IDENTIFICATION: Hematopoietic stem cell transplantation has significant psychosocial impacts on pediatric sibling donors, including emotional distress, guilt, and anxiety. The aim of this qualitative review is to explore their experiences and the challenges they face. LITERATURE SEARCH: A systematic review of qualitative studies of sibling donors was conducted using JBI guidelines. A search of MEDLINE®, Scopus®, CINAHL®, PsycINFO®, and ProQuest identified nine qualitative studies involving 70 sibling donors. DATA EVALUATION: Studies were critically appraised using JBI methodology for systematic reviews of qualitative evidence. Data were synthesized to understand psychosocial experiences of sibling donors. SYNTHESIS: The following four main themes emerged: (a) Sibling donors felt trapped and experienced mixed emotions about donating, (b) family life was significantly disrupted after the sibling's illness, (c) donors developed a sense of pride from being able to help their sibling, and (d) the donation process required better emotional support for the donors. IMPLICATIONS FOR PRACTICE: Pediatric healthcare professionals should offer specialized psychosocial support to sibling donors. Additional qualitative research is needed to assess the long-term psychosocial effects on these donors.
Oncol Nurs Forum
· 2025 Oct · PMID 41123395
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PURPOSE: To culturally adapt Helping Her Heal (HHH), a nurse-delivered educational counseling intervention for spouse caregivers of women with breast cancer, for applicability in Ghana, Africa. PARTICIPANTS & SETTING...PURPOSE: To culturally adapt Helping Her Heal (HHH), a nurse-delivered educational counseling intervention for spouse caregivers of women with breast cancer, for applicability in Ghana, Africa. PARTICIPANTS & SETTING: Four spouses of women with breast cancer and two nurses in breast clinics were interviewed to review HHH for adaptability. METHODOLOGIC APPROACH: The Ecological Validity Model guided the cultural adaptation of HHH to review the intervention, have Ghanaian nurses review the HHH manuals, modify the original HHH to the targeted demographic, verify the adaptation, and review for acceptability. FINDINGS: The intervention manuals needed minor modifications in three of the eight dimensions of the Ecological Validity Model: language, content, and metaphor. The structure and focus of each intervention session did not need changes. IMPLICATIONS FOR NURSING: Findings from this study have laid the groundwork for the cultural adaption of studies. This study is the first step in the process of adapting an intervention for spouse caregivers that will be used by breast cancer nurses in the delivery of care.
Oncol Nurs Forum
· 2025 Oct · PMID 41123394
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OBJECTIVES: To assess the impact of Snyder's hope theory-guided nursing care combined with continuity of care on postoperative individuals with glioma undergoing chemotherapy. SAMPLE & SETTING: 112 patients with glio...OBJECTIVES: To assess the impact of Snyder's hope theory-guided nursing care combined with continuity of care on postoperative individuals with glioma undergoing chemotherapy. SAMPLE & SETTING: 112 patients with glioma receiving postoperative chemotherapy were randomly assigned to control and observation groups. METHODS & VARIABLES: The control group received routine nursing whereas the observation group received additional care based on Snyder's hope theory, combined with continuous nursing. Negative emotions, self-care agency, cancer-related fatigue, hope levels, quality of life, adverse reactions, and nursing satisfaction were compared between the groups. RESULTS: The observation group showed significantly lower anxiety and depression (p < 0.05) and higher self-care advocacy, hope levels, and quality of life than the control group (p < 0.05). Fatigue and the incidence of adverse reactions were significantly lower in the observation group (p < 0.05). Nursing satisfaction in the observation group was significantly higher. IMPLICATIONS FOR NURSING: Snyder's hope theory-guided nursing care with continuity of care improves psychological well-being, self-care agency, and quality of life, and reduces fatigue and side effects among individuals with glioma undergoing chemotherapy.
DiValerio Gibbs K, Pasumarthi T, Watson MA
… +7 more, Tangri N, Sayal S, Bickett S, Thomas T, Backler C, Clark C, Morgan RL
Oncol Nurs Forum
· 2025 Oct · PMID 41123393
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PROBLEM IDENTIFICATION: This systematic review was conducted to inform the development of clinical practice guidelines on the management of extravasation of antineoplastic agents in patients with cancer. LITERATURE SEARC...PROBLEM IDENTIFICATION: This systematic review was conducted to inform the development of clinical practice guidelines on the management of extravasation of antineoplastic agents in patients with cancer. LITERATURE SEARCH: PubMed®, Embase®, CINAHL®, and Cochrane databases were searched for eligible studies from June 2014 to June 2024. Citations of guidelines and a previous systematic review were reviewed for records that met eligibility criteria. Two reviewers independently screened titles, abstracts, and full texts for inclusion. DATA EVALUATION: Two independent reviewers assessed all studies that met inclusion criteria using the Risk of Bias in Nonrandomized Studies of Interventions for cohort studies and JBI critical appraisal tool for case series. The certainty of evidence was assessed using GRADE (Grading of Recommendations Assessment, Development, and Evaluation) methodology. SYNTHESIS: For patients who have an extravasation of an antineoplastic agent, although there is very low certainty in the evidence overall, interventions include administration of an antidote, compress, and surgical referral or escalation of care for extravasation of central lines. IMPLICATIONS FOR PRACTICE: Antidotes, application of a compress, and referral for surgical or wound care are effective strategies for managing extravasation of antineoplastic agents.
Oncol Nurs Forum
· 2025 Aug · PMID 40849929
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To commemorate ONS's 50th anniversary in 2025, throughout the year, we will be reprinting seminal editorials written by former editors of the Oncology Nursing Forum and the Clinical Journal of Oncology Nursing that have...To commemorate ONS's 50th anniversary in 2025, throughout the year, we will be reprinting seminal editorials written by former editors of the Oncology Nursing Forum and the Clinical Journal of Oncology Nursing that have had.
Oncol Nurs Forum
· 2025 Aug · PMID 40849928
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The implications of AI-generated peer reviews are concerning, particularly when not disclosed. If students are already turning to AI to complete academic tasks, it is not hard to imagine researchers are doing the same.The implications of AI-generated peer reviews are concerning, particularly when not disclosed. If students are already turning to AI to complete academic tasks, it is not hard to imagine researchers are doing the same.
Jung A, Crowder V, Chan YN
… +10 more, Klemm D, Tan KR, Poor EH, Okanlawon Bankole A, Anderson DS, Coppola S, Pergolotti M, Schwartz TA, Richardson DR, Leak Bryant A
Oncol Nurs Forum
· 2025 Aug · PMID 40849925
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PURPOSE: To explore perspectives of older adults (aged 60 years or older) with acute myeloid leukemia (AML) on their physical function and mobility, assessed at three time points during treatment with a hypomethylating a...PURPOSE: To explore perspectives of older adults (aged 60 years or older) with acute myeloid leukemia (AML) on their physical function and mobility, assessed at three time points during treatment with a hypomethylating agent and venetoclax (HMA + VEN). PARTICIPANTS & SETTING: Participants were older adults with AML (N = 17) receiving HMA + VEN at a comprehensive cancer center. Most were male and aged 64-89 years (median age = 75 years). METHODOLOGIC APPROACH: This study used a longitudinal qualitative approach with semistructured interviews at cycles 1, 2, and 7 of chemotherapy. Interviews were audio recorded, transcribed, coded, and analyzed using thematic analysis. FINDINGS: Four themes were identified: reduced mobility and limited options for physical activities (cycle 1), periodic changes in mobility and energy level (cycle 2), acceptance and adaptation to changed mobility (cycle 7), and strategies to stay active. IMPLICATIONS FOR NURSING: Substantial challenges with physical function and mobility exist for older adults undergoing treatment for AML. Oncology nurses should anticipate patient needs, provide appropriate care, and make referrals to address physical and functional needs before and during HMA + VEN treatment.
Gyan KG, Dunnack Yackel H, Effiong D
… +2 more, Escobar Jones C, Wamai R
Oncol Nurs Forum
· 2025 Aug · PMID 40849924
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OBJECTIVES: To examine the cervical cancer screening beliefs and practices of Black immigrant women from sub-Saharan African or Caribbean countries living in Massachusetts. SAMPLE & SETTING: 19 women who self-identif...OBJECTIVES: To examine the cervical cancer screening beliefs and practices of Black immigrant women from sub-Saharan African or Caribbean countries living in Massachusetts. SAMPLE & SETTING: 19 women who self-identified as being sub-Saharan African or Caribbean, spoke English, were foreign-born, were aged 25-65 years, and had been living in the United States for at least six months were included. METHODS & VARIABLES: A qualitative descriptive design and thematic analysis were used. A semistructured interview guide was developed based on the PEN-3 cultural model. RESULTS: Facilitators of cervical cancer screening included a sense of personal responsibility to maintain one's health, cultivating trust within the healthcare system, and cultivating community support. Barriers included pain and fear, navigating a new identity as a Black immigrant, a lack of formal education on sexual health, and challenges accessing the healthcare system. IMPLICATIONS FOR NURSING: Culturally tailored resources and community partnerships may be useful in promoting cervical cancer screening in Black immigrant women.
Fennimore LA, Battista V, Leak Bryant A
… +2 more, Paice JA, Ferrell B
Oncol Nurs Forum
· 2025 Aug · PMID 40849923
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PURPOSE: To describe intrinsic factors influencing role retention of oncology advanced practice providers (APPs). PARTICIPANTS AND SETTING: The current study examined 66 advanced practice RNs and three physician assistan...PURPOSE: To describe intrinsic factors influencing role retention of oncology advanced practice providers (APPs). PARTICIPANTS AND SETTING: The current study examined 66 advanced practice RNs and three physician assistants completing a palliative care course for oncology providers offered by the End-of-Life Nursing Education Consortium through a grant from the National Cancer Institute. METHODOLOGIC APPROACH: Participants were asked "Why do you stay?" on the final course evaluation. Deidentified qualitative responses were sorted using thematic content analysis to identify key themes affecting oncology APP retention. FINDINGS: Five themes emerged from the analysis: calling/passion, personal or family history, people with cancer, challenging work/making a difference, and relationships with the oncology team. IMPLICATIONS FOR PRACTICE: Despite the essential role of oncology APPs, little is known about what is important to them and what keeps them in the profession, particularly in the current healthcare environment. Stakeholders concerned about delivering quality cancer care must recognize the values and meaning that oncology APPs ascribe to their roles to support and retain this essential workforce. Understanding these factors will inform leaders of the issues that affect and cultivate the work of oncology APPs.
Oncol Nurs Forum
· 2025 Aug · PMID 40849922
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OBJECTIVES: To determine the relationship between chemotherapy-induced peripheral neuropathy (CIPN) severity and centrosomal protein 72 (CEP72) genotype in young adults receiving paclitaxel or vincristine. SAMPLE & S...OBJECTIVES: To determine the relationship between chemotherapy-induced peripheral neuropathy (CIPN) severity and centrosomal protein 72 (CEP72) genotype in young adults receiving paclitaxel or vincristine. SAMPLE & SETTING: 50 young adults aged 21-39 years who were expected to receive a cumulative dose of at least 7 mg vincristine or 700 mg/m2 paclitaxel for the treatment of cancer were recruited from Dana-Farber Cancer Institute. METHODS & VARIABLES: Participants completed a CIPN assessment tool and provided a blood sample before the first infusion. Participants completed the assessment tool at two additional time points. DNA was genotyped for CEP72 rs924607. CIPN scores were compared between those with the TT versus the CC or CT genotype over time using linear mixed-effects models. RESULTS: Young adults receiving vincristine with the TT CEP72 genotype experienced higher CIPN severity by the final time point, but the differences were not statistically significant (p > 0.05). IMPLICATIONS FOR NURSING: Future work to validate biomarkers like CEP72 may allow clinicians to identify patients who may benefit from altered chemotherapy dosages relative to CIPN risk.
Oncol Nurs Forum
· 2025 Aug · PMID 40849927
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PURPOSE: To examine the roles and experiences of mothers diagnosed with breast cancer. PARTICIPANTS AND SETTING: The study was conducted from June to September 2024 with 19 patients being treated for breast cancer in Tür...PURPOSE: To examine the roles and experiences of mothers diagnosed with breast cancer. PARTICIPANTS AND SETTING: The study was conducted from June to September 2024 with 19 patients being treated for breast cancer in Türkiye. METHODOLOGIC APPROACH: Data were collected through individual, in-depth interviews and analyzed using Colaizzi's descriptive phenomenologic approach. FINDINGS: Data analysis revealed four main themes and six subthemes. The four main themes were (a) Beyond Diagnosis: A Mother's Resilience Through Cancer, (b) Between Mother and Patient: The Challenge of Maintaining Motherhood Amid Illness, (c) Between Truth and Protection: The Child's Emotional Response to Parental Cancer, and (d) Family as Lifeline: Support Systems in the Face of Cancer. IMPLICATIONS FOR NURSING: Breast cancer diagnosis and treatment processes negatively affect women's ability to fulfill the role of motherhood, and women experience several psychosocial problems related to their role. Oncology nurses should monitor the difficulties, feelings, and thoughts that mothers with breast cancer experience and support patients in developing individual coping methods.