Journal Of Clinical And Diagnostic Research[JOURNAL]
Sun
200 papers
Epididymal Cystic Lymphangioma Presenting as Scrotal Swelling in a Post Surgery Case of Carcinoma Rectum- A Case Report.
Haroon M, Nisha Y, Iqubal K
J Clin Diagn Res · 2017 Sep · PMID 29207807 · Full text
Cystic lymphangiomas are usually congenital malformations of draining lymphatic channels with most common sites including neck, axilla, mediastinum and retroperitoneum. Occurrence of lymphangiomas in scrotum or inguinal...
Cystic lymphangiomas are usually congenital malformations of draining lymphatic channels with most common sites including neck, axilla, mediastinum and retroperitoneum. Occurrence of lymphangiomas in scrotum or inguinal region is a rare entity and epididymal origin of these lesions is even more infrequent. We herein report a case of epididymal lymphangioma detected on USG, which developed after surgical abdominal lymph nodal dissection in an adult patient of carcinoma rectum presenting as painless scrotal swelling.
Rapunzel Syndrome.
Lalith S, Gopalakrishnan KL, Ilangovan G … +1 more , Jayajothi A
J Clin Diagn Res · 2017 Sep · PMID 29207806 · Full text
A bezoar refers to a mass of undigestible foreign material found in the gastrointestinal tract, mainly stomach. The second most common bezoar is the trichobezoar, which usually occurs in the young psychiatric female pati...
A bezoar refers to a mass of undigestible foreign material found in the gastrointestinal tract, mainly stomach. The second most common bezoar is the trichobezoar, which usually occurs in the young psychiatric female patients with history of trichotillomania and trichophagia. This is a case report of a 12 -year-old female patient came with complaints of diffuse abdominal pain, vomiting, and constipation. Ultrasound, Barium X-ray and Computed Tomography scan were done, which suggested trichobezoar. Thus, trichobezoar should be considered as differential diagnosis of abdominal pain in young female patients with associated psychiatric complaints. A review is presented here, as a high index of suspicion for better diagnostic facilities which can help in timely diagnosis and intervention, to prevent further complications like intestinal obstruction, perforation and mortality in such children.
Benign Lesions on Screening Mammography: Increasing Diagnostic Confidence in a Hitherto Unscreened Population.
Joshi P, Sharma R
J Clin Diagn Res · 2017 Sep · PMID 29207805 · Full text
INTRODUCTION: Screening mammography is used for detection of breast cancer and is interpreted using the Breast Image Reporting and Data System (BIRADS) convention. It is not routinely offered to women in countries which...
INTRODUCTION: Screening mammography is used for detection of breast cancer and is interpreted using the Breast Image Reporting and Data System (BIRADS) convention. It is not routinely offered to women in countries which do not have a national screening programme resulting in a challenge for the radiologist who has to interpret these in the absence of previous mammograms. AIM: To analyse benign and probably benign lesions in screening mammograms in a hitherto unscreened population and suggest protocols to increase diagnostic confidence. MATERIALS AND METHODS: Screening mammograms of 362 asymptomatic women in the age range of 40 to 60 years carried out over a two year period were retrospectively analysed. Patients of breast cancer and those who had palpable lumps were excluded from the study. All images were analysed in standard Mediolateral Oblique (MLO) and Craniocaudal (CC) projections with additional views wherever necessary. Corroborative ultrasound had been carried out wherever indicated in the opinion of the interpreting radiologist. The mammograms were finally classified according to the BIRADS convention. RESULTS: Of the total number of 362 women screened, most of whom did not have any previous mammogram, 162 were reported as BIRADS I, 179 as BIRADS II and 18 as BIRADS III. The mammograms reported as BIRADS II had various findings including dystrophic calcification/macrocalcification, vascular calcification, simple cysts and fibroadenomas. Only 26 (16.04%) of the BIRADS I mammograms had undergone further evaluation with Ultrasound (US) due to dense breasts or asymmetrical involution of breast tissue whereas 76 (42.5%) of the BIRADS II mammograms had undergone further evaluation with US to characterize lesions like cysts and fibroadenomas, but occasionally also for benign clustered calcification. Of BIRADS III mammograms, 12 (66.6%) had required US correlation to exclude a mass in cases with dense breasts. The increased likelihood of ultrasound corroboration in BIRADS II and BIRADS III was analysed using the Chi square test and was statistically significant. CONCLUSION: In the absence of previous screening mammograms, a small number of BIRADS I mammograms and a significant number of BIRADS II and BIRADS III mammograms undergo a corroborative US examination. The addition of supplemental US to the evaluation of these lesions increase diagnostic confidence and lesion characterization in a population which is not subject to routine screening.
An Evaluation of Dental Crowding in Relation to the Mesiodistal Crown Widths and Arch Dimensions in Southern Indian Population.
Das PJ, Dkhar W, Pradhan A
J Clin Diagn Res · 2017 Sep · PMID 29207804 · Full text
INTRODUCTION: With the advancement in imaging technology, 3D dental computed tomography plays a very significant role in orthodontic treatment and diagnosis. AIM: To evaluate dental crowding in relation to the mesiodista...
INTRODUCTION: With the advancement in imaging technology, 3D dental computed tomography plays a very significant role in orthodontic treatment and diagnosis. AIM: To evaluate dental crowding in relation to the mesiodistal crown widths and arch dimensions and also to determine the differences of dental crowding among males and females, in Southern Indian population. MATERIALS AND METHODS: A total of 132 subjects were divided into two groups: crowded and non-crowded, each comprising 66 subjects (33 males and 33 females), aged between 15 and 35 years, who were referred for computed tomography scan of brain to the radiology department, were selected. During the scan both the jaws were included in the image. The 2D images were converted to 3D images using volume rendering software. By using measurement tool, individual and collective mesiodistal crown widths of canine, first and second premolar and first molar and arch perimeter of both the maxillary and mandibular jaws were measured. RESULTS: When both the gender were considered, the mesiodistal crown widths and arch perimeter were statistically significant for dental crowding in both mandibular jaw (p-value=0.001 for both mesiodistal crown width and arch perimeter) and maxillary jaw (p-value=0.016 for mesiodistal crown width and 0.002 for arch perimeter). However, when analysed separately, in males the mesiodistal crown widths and arch perimeter were statistically significant for dental crowding in both mandibular jaw (p-value=0.001 for mesiodistal crown width and 0.002 for arch perimeter) and maxillary jaw (p-value=0.002 for mesiodistal crown width and 0.001 for arch perimeter) but in females it was not statistically significant in any jaw (p-value=0.7 for mesiodistal crown width and 0.06 for arch perimeter in mandibular jaw and p-value=0.2 for mesiodistal crown width and 0.9 for arch perimeter for maxillary jaw). The crowded group had larger tooth size and smaller arch perimeter. CONCLUSION: This study concluded that in males, both the factors i.e., mesiodistal crown width and arch dimensions contributed to dental crowding and the crowded dentition had larger mesiodistal tooth size and smaller arch dimensions; whereas, in females both the factors were not responsible for crowding in Southern Indian population.
Radiological Manifestations of Pulmonary Tuberculosis - A Comparative Study between Immunocompromised and Immunocompetent Patients.
Mathur M, Badhan RK, Kumari S … +2 more , Kaur N, Gupta S
J Clin Diagn Res · 2017 Sep · PMID 29207803 · Full text
INTRODUCTION: Pulmonary tuberculosis has atypical radiological manifestations in patients with underlying immunocompromised disease like diabetes and human immunodeficient virus infection. Computed tomography has importa...
INTRODUCTION: Pulmonary tuberculosis has atypical radiological manifestations in patients with underlying immunocompromised disease like diabetes and human immunodeficient virus infection. Computed tomography has important role in such patients for early diagnosis of disease and management to minimize complication. AIM: To evaluate and compare the computed tomography chest features of pulmonary tuberculosis in between immunocompromised patients and immunocompetent patients. MATERIALS AND METHODS: This cross-sectional study was conducted in the hospital on newly diagnosed 60 pulmonary tuberculosis patients of which 30 patients had no underlying disease (Immunocompetent Group) and 30 patients had diabetes mellitus or were human immunodeficiency virus seropositive (Immunocompromised Group). CT scan of chest were evaluated for each patient. RESULTS: In immunocompetent patients, 36.7% had radiologically atypical presentation,90% had nodular opacities, 73.3% had consolidation, 23.3% had lymphadenopathy, 60% had cavitation and cavitatory lesion were single in 94.4% patients. Isolated upper lung field were involved in 60% patients. In immunocompromised patients 76.7% had radiologically atypical presentation, 66.7% had nodular opacities, 46.7% had consolidation, 63.3% had lymphadenopathy, 20% had cavitation and cavitatory lesions were multiple in 60% patients. Isolated lower lung field were involved in 23.3% patients. CONCLUSION: We concluded that immunocompromised patients have more atypical involvement of lung fields, higher prevalence of lymphadenopathy as compared to immunocompetent patients. Diabetic patients have multiple cavitatory lesions as compared to non-diabetic patients. HIV seropositive patients have more prevalence of lymphadenopathy as compared to HIV seronegative patients.
Image Findings of Solid Pseudopapillary Neoplasms of the Pancreas on Multiphasic Multidetector CT Scan-A Single Institute Experience from Southern India.
Rai S, Prabhu S, Rai S … +4 more , Nirupama M, Adiga DS, Kumar A, Chakraborti S
J Clin Diagn Res · 2017 Sep · PMID 29207802 · Full text
INTRODUCTION: Solid Pseudopapillary Neoplasms (SPN) are uncommon pancreatic tumours and are slow growing with uncertain malignant potential, showing female preponderance. Postoperative prognosis is good and metastasis is...
INTRODUCTION: Solid Pseudopapillary Neoplasms (SPN) are uncommon pancreatic tumours and are slow growing with uncertain malignant potential, showing female preponderance. Postoperative prognosis is good and metastasis is rare. AIM: To summarise the imaging and pathological features of seven cases of SPN in three years period, from January 2013 to January 2016. MATERIALS AND METHODS: In this retrospective study the imaging features of seven cases on triphasic multidetector Computed Tomogram (CT), a 16-slice scanner, were reviewed along with CT-guided Fine Needle Aspiration Cytology (FNAC) and histopathological examination. Statistics were expressed in terms of percentiles. RESULTS: All cases were female patients with an age range of 13-35 years (mean: 23.3 years). On CT assessment, the size of the tumours varied from 2.5-14 cm (mean: 5.3 cm). All these tumours were well capsulated and round to oval in shape. In four out of seven cases, the tumour was located in the tail of pancreas. All the solid enhancing portions showed moderate enhancement of at least 20-30 HU compared to unenhanced scan, on the other hand the cystic parts remained unenhanced with <5 HU variation in comparison to the plain scan. Histopathological examination exhibited characteristic poorly cohesive cuboidal cells arranged in papillaroid pattern having fine nuclear chromatin with nuclear grooves. CONCLUSION: Solid pseudopapillary neoplasm is a high diagnostic possibility in case of a young female having pancreatic mass and needs to be evaluated with triphasic contrast enhanced CT scan, followed by FNAC and or histopathological examination.
Autoimmune Haemolytic Anaemia-A Spectrum of Presentation in Children.
Singh A, Mandal A, Patel A … +1 more , Mishra S
J Clin Diagn Res · 2017 Sep · PMID 29207801 · Full text
Autoimmune Haemolytic Anaemias (AIHAs) are rare in children. They can be either a primary disease or secondary to/triggered by a host of other clinical conditions. We present five interesting cases of paediatric AIHA ass...
Autoimmune Haemolytic Anaemias (AIHAs) are rare in children. They can be either a primary disease or secondary to/triggered by a host of other clinical conditions. We present five interesting cases of paediatric AIHA associated with infections (viral, bacterial and atypical) and autoimmune diseases {Systemic Lupus Erythematosus (SLE) and Autoimmune Hepatitis (AIH)}. The H1N1 influenza associated AIHA responded to oseltamivir and Intravenous Immunoglobulin (IvIg) while the cases secondary to and pneumococcal bacteraemia required only treatment of the primary infection. AIHA with SLE responded well to corticosteroid therapy but the patient with AIH and AIHA succumbed to severe liver failure. Rest of the four cases with good response to therapy did not have any recurrence/relapse of AIHA during their follow up periods.
Right Pulmonary Venous Atresia: A Rare Cause for Recurrent Unilateral Pneumonia.
Patil PP
J Clin Diagn Res · 2017 Sep · PMID 29207800 · Full text
Recurrent unilateral pneumonia poses a diagnostic dilemma for all paediatricians. Isolated pulmonary venous atresia is an uncommon entity, which presents with recurrent unilateral pulmonary infections, dyspnoea on exerti...
Recurrent unilateral pneumonia poses a diagnostic dilemma for all paediatricians. Isolated pulmonary venous atresia is an uncommon entity, which presents with recurrent unilateral pulmonary infections, dyspnoea on exertion and haemoptysis. It is associated with significant mortality and morbidity. Owing to rarity of condition, there may be some difficulties in the diagnosis and therapy. Pulmonary angiography is the investigation of choice. However, the current multislice CT scanners may obviate the need for pulmonary angiography. We report a two-year-old child with this rare congenital malformation and discuss diagnostic modalities and management options.
Change in Bone Mineral Density and Role of Vitamin D and Calcium Supplementation During Treatment of First Episode Nephrotic Syndrome.
Yadav VK, Sharma S, Debata PK … +3 more , Patel S, Kabi BC, Aggrawal KC
J Clin Diagn Res · 2017 Sep · PMID 29207799 · Full text
INTRODUCTION: Nephrotic Syndrome (NS) is one of the common illnesses in childhood. Oral glucocorticoids are mainstay of treatment, which are known to cause various short term and long term adverse effects including osteo...
INTRODUCTION: Nephrotic Syndrome (NS) is one of the common illnesses in childhood. Oral glucocorticoids are mainstay of treatment, which are known to cause various short term and long term adverse effects including osteoporosis. Children with first episode and infrequent relapsing NS are not prescribed Calcium (Ca) and Vitamin D (VitD) supplements routinely. AIM: To observe change in Bone Mineral Density (BMD) in children during first episode of NS and role of VitD and Ca supplementation during the treatment of first episode of NS. MATERIALS AND METHODS: A double blind randomized control trial was conducted in Department of Paediatrics at a tertiary care center in New Delhi, India, from October 2011 to March 2013. Three groups were made, each having sample size of 20. Group A (intervention group) consisted of first episode NS patients who received steroids along with VitD and Ca supplements. Group B (placebo group) had children with first episode of NS treated with steroids and placebo. Biochemical tests and BMD assessment were done at start and after three months of steroid treatment. Groupwise differences in BMD, VitD, Ca, Phosphate (PO) and Alkaline Phosphatase (ALP) were assessed at baseline and after three months through Analysis Of Variance (ANOVA). Linear regression models for repeated measures were used to test the association between different variables and BMD and also between various study groups. RESULTS: Among study population, Group B had significant decrease in VitD levels (28.85±5.52 ng/dl to 14.22±1.36 ng/dl) than to Group A (23.59±6.08 ng/dl to 13.27±1.35 ng/dl) after three months of steroid treatment. Similarly BMD decreased significantly in Group B (-0.033g/cm) as compared to Group A (0.001g/cm) showing significant decrease in VitD and BMD in children with first episode of NS after three months of steroid treatment whereas use of VitD and Ca supplements improves the deficit. CONCLUSION: Ca and VitD supplement should be used during treatment of first episode of NS, but further studies are required to ascertain the adequate dose for the same.
Does Vitamin D Supplementation Improve Glycaemic Control In Children With Type 1 Diabetes Mellitus? - A Randomized Controlled Trial.
Sharma S, Biswal N, Bethou A … +3 more , Rajappa M, Kumar S, Vinayagam V
J Clin Diagn Res · 2017 Sep · PMID 29207798 · Full text
INTRODUCTION: Vitamin D endocrine system is a potential immune system modulator and has been implicated in the pathogenesis of several autoimmune diseases including Type 1 Diabetes Mellitus (T1DM). Studies have demonstra...
INTRODUCTION: Vitamin D endocrine system is a potential immune system modulator and has been implicated in the pathogenesis of several autoimmune diseases including Type 1 Diabetes Mellitus (T1DM). Studies have demonstrated an inverse risk relationship between T1DM and Vitamin D levels and also, shown a reduced risk of the disease with its supplementation. AIM: To evaluate the role of Vitamin D as an adjuvant in improving glycaemic control and residual pancreatic beta-cell function. Primary outcome was the mean change in HbA1c levels over a period of six months. MATERIALS AND METHODS: This double-blinded randomized controlled trial was done in a tertiary care hospital, Southern India and included 52 children aged 1-18 years with T1DM, with 26 participants each in the intervention and standard of care arm. Oral Vitamin D therapy was administered once a month for six months in addition to insulin in intervention arm while only insulin was continued for other arm. Plasma HbA1c, serum 25-Hydroxy vitamin D (25OHD), insulin dose and C-peptide were measured at baseline and repeated after 6 months. RESULTS: Prevalence of Vitamin D deficiency was as high as 63.5% i.e., 33 of total 52 children with T1DM. The mean C-peptide levels were significantly high in intervention arm as compared to standard of care after six months. However, there was no significant difference in HbA1c, and insulin requirement at six months between the two groups. No adverse events due to Vitamin D therapy were noted. CONCLUSION: Oral Vitamin D may serve as an adjuvant to insulin therapy for children with T1DM by augmenting residual beta-cell function and improving insulin secretion. However, a significant decrease in HbA1c level and requirement for exogenous insulin was not achieved in our study.
Audit of Organic Acidurias from a Single Centre: Clinical and Metabolic Profile at Presentation with Long Term Outcome.
Sindgikar SP, Shenoy KD, Kamath N … +1 more , Shenoy R
J Clin Diagn Res · 2017 Sep · PMID 29207797 · Full text
INTRODUCTION: Organic Acidurias (OA) accounts between 10% and 40% of confirmed Inborn Errors of Metabolism (IEM) in India. With prompt recognition and management, better survival but adverse neurodevelopmental outcome is...
INTRODUCTION: Organic Acidurias (OA) accounts between 10% and 40% of confirmed Inborn Errors of Metabolism (IEM) in India. With prompt recognition and management, better survival but adverse neurodevelopmental outcome is reported. AIM: To study the clinical and metabolic presentation, management with immediate and long term outcome of symptomatic children with confirmed OA. MATERIALS AND METHODS: Hospital based study of symptomatic children diagnosed to have OA between 2003 and 2009 and the survivors followed up over next five years. Diagnosis was based on clinical and metabolic presentation and confirmed by spectrometry analyses of urine and blood. Management, immediate outcome, compliance to treatment and recurrence of crises were documented. Neurodevelopmental outcome was assessed in follow up. Mean with Standard Error (Mean ± SE) and frequencies with percentages were calculated. RESULTS: Of 72 cases suspected to have IEM, 38 (52.8%) were confirmed of (IEM), and out of which 15 (39.5%) had OA. Methyl malonic acidemia, multiple carboxylase deficiency and Propionic Acidemia (PA) constituted the largest proportion. Neurodevelopmental issues (73.3%) and metabolic crisis (53.3%) were common presenting features. Mean ± SE of ammonia was 639.0±424.1 μg/dl and lactate was 33.6±4.9 mg/dl. Mean pH, bicarbonate, and anion gap was 7.27±0.07, 14.1±2.3 and 17.9±2.3 respectively. Management was protocol based. Death was reported in two cases of PA; other morbidities were seen in five. Recurrent crisis (46.7%) complicated the follow up in survivors. Spasticity, extrapyramidal movement disorder, intellectual subnormality, autism spectrum, attention deficit hyperactivity disorder and sensory neural deafness were seen amongst survivors, in spite of compliance to therapy. CONCLUSION: OA is part of differential diagnosis in sick children and treatment needs to be prompt and specific. Prognosis is guarded even with long term cofactor supplementation in the symptomatic.
Clinico-Aetiological Study of Severe and Very Severe Pneumonia in Two Months to Five Years Children in a Tertiary Health Care Centre in Odisha, India.
Champatiray J, Satapathy J, Kashyap B … +1 more , Mondal D
J Clin Diagn Res · 2017 Sep · PMID 29207796 · Full text
INTRODUCTION: Pneumonia is a major cause of mortality under five-year-old children. In spite of recent advances in management, there is paucity of data on clinical, aetiological profile of severe and very severe pneumoni...
INTRODUCTION: Pneumonia is a major cause of mortality under five-year-old children. In spite of recent advances in management, there is paucity of data on clinical, aetiological profile of severe and very severe pneumonia among under five-year-old children in developing countries. AIM: To determine the clinico-aetiological factors of severe and very severe pneumonia and its outcome in children aged two -months to five-years in a tertiary health care centre in Odisha, India. MATERIALS AND METHODS: This was a prospective observational study. All the patients between two-months to five-years age admitted to SCB Medical College, Cuttack, Odisha, India, were screened for features of severe and very severe pneumonia based on WHO diagnostic criteria, over a one year period. Out of 10300 patients admitted to our hospital during the study period; 141 cases were included in the study. Their clinical parameters were recorded and were followed up till discharge or death. Continous variables were analyzed using Student t-test or Mann-Whitney U test whereas categorical data were analyzed using Pearson Chi square test or Fischer Exact test. RESULTS: Out of 141 patients included in the study, cough, tachypnea and chest retractions were present in 100% cases while fever in 97.1% (137) cases. In 17% (24) cases, bacterial pathogen was isolated. Most common organism being 8.51% (12) followed by 6.4% (9). Higher mortality 11.34% (16) was found among patients presenting after three days of illness (p=0.048). About 17% (24) patients developed complications. Common complications were sepsis 5.6% (8), CCF 4.2% (6) and empyema 4.2% (6). Higher mortality 22 (15.6%) was observed in very severe pneumonia group (p=0.003). CONCLUSION: The incidence of severe and very severe pneumonia was higher in infancy. Rainy and winter season were associated with higher incidence of disease. Bottle feeding practice and smoking were significantly associated with more severe disease. Death rate was high among patients admitted to hospital after three days of onset of illness, so early referral is indicated for better outcome.
Association between Vascular Endothelial Markers and Carotid Intima-Media Thickness in Children and Adolescents with Type 1 Diabetes Mellitus.
Rostampour N, Fekri K, Hashemi-Dehkordi E … +1 more , Obodiat M
J Clin Diagn Res · 2017 Sep · PMID 29207795 · Full text
INTRODUCTION: Type 1 Diabetes Mellitus (T1DM) is one of the important risk factor for cardiovascular disease. Endothelial dysfunction and increased Carotid Intima-Media Thickness (CIMT) result in cardiovascular complicat...
INTRODUCTION: Type 1 Diabetes Mellitus (T1DM) is one of the important risk factor for cardiovascular disease. Endothelial dysfunction and increased Carotid Intima-Media Thickness (CIMT) result in cardiovascular complications. Vascular Cell Adhesion Molecule-1 (VCAM-1) and Intercellular Adhesion Molecule-1 (ICAM-1) are two adhesion molecules that are markers of early atherosclerosis and play a significant role in developing atherosclerosis. AIM: To evaluate CIMT and its association with the levels of ICAM-1 and VCAM-1 in children and adolescents with T1DM. MATERIALS AND METHODS: In this descriptive, cross-sectional study conducted between April 2013 and September 2014, 29 children aged 7-20 years with T1DM for at least two years and 29 age and sex-matched, healthy individuals were evaluated. Plasma level of ICAM-1 and VCAM-1 was measured by ELISA, and CIMT via Doppler ultrasound was also assessed. The data were analysed by t-test and Pearson's correlation coefficient in SPSS 16.0 (p≤0.05). RESULTS: Independent t-test indicated that there is a significant difference in ICAM-1 level between the patients and controls (p<0.001). Further, CIMT was significantly higher in diabetic subject (p<0.001). CIMT was not significantly associated with the level of VCAM-1 and ICAM-1 in the patients (p>0.5). CONCLUSION: ICAM-1 and VCAM-1 were not associated with CIMT but, CIMT and level of ICAM-1 were significantly, higher in diabetic patients, and therefore could be used as useful tools for identification of early atherosclerosis in children and adolescents with T1DM.
Non Traumatic Fracture of Pedunculated Osteochondroma: Conservative Management of a Rare Case.
Senel A, Sukur E, Topcu HN
J Clin Diagn Res · 2017 Sep · PMID 29207794 · Full text
Fracture of a pedunculated osteochondroma is a rare complication for which surgical treatment is usually advocated. In this report, we present the functional and radiological outcomes of a case of a conservatively treate...
Fracture of a pedunculated osteochondroma is a rare complication for which surgical treatment is usually advocated. In this report, we present the functional and radiological outcomes of a case of a conservatively treated fracture of a pedunculated osteochondroma. A 26-year-old man with no history of trauma presented with acute onset of left knee pain, oedema, and limited range of motion. Radiological assessment revealed a fracture of a pedunculated osteochondroma. It was treated conservatively with an elastic bandage and non-steroidal anti-inflammatory drugs, and union was achieved by the 12-week follow-up, with no complications. Although surgical treatment is usually advocated for a pedunculated osteochondroma fracture, conservative treatment should be the first approach to avoid complications of surgical intervention.
Posterior Dislocation of Subtalar Joint without Associated Fracture: A Case Report and Review of Literature.
Gaba S, Kumar A, Trikha V … +2 more , Das S, Agrawal P
J Clin Diagn Res · 2017 Sep · PMID 29207793 · Full text
Posterior subtalar dislocation is an exceedingly rare entity. Clinically, the appearance of the foot can simulate a complex fracture dislocation. It is important to recognize that not all posterior subtalar dislocations...
Posterior subtalar dislocation is an exceedingly rare entity. Clinically, the appearance of the foot can simulate a complex fracture dislocation. It is important to recognize that not all posterior subtalar dislocations are true posterior dislocations. We report a true posterior subtalar dislocation in a 34-year-old female, managed promptly with closed reduction and resulting in an excellent functional outcome. A chronic dislocation or an irreducible dislocation may need open reduction.
Clinical Evaluation of Efficacy and Performance of All-Poly Tibial Freedom Total Knee System for Treating Osteoarthritis Patients: Three-Year Follow Up Study.
Singh A, Singh KK
J Clin Diagn Res · 2017 Sep · PMID 29207792 · Full text
INTRODUCTION: Advancement in technology in terms of design and building materials has made Total Knee Replacement (TKR) a highly effective, safe, and predictable orthopedic procedure. AIM: To review the clinical outcomes...
INTRODUCTION: Advancement in technology in terms of design and building materials has made Total Knee Replacement (TKR) a highly effective, safe, and predictable orthopedic procedure. AIM: To review the clinical outcomes for efficacy and performance of Freedom Total Knee System for the management of Osteoarthritis (OA), at a minimum of three years follow up. MATERIALS AND METHODS: For this retrospective, post-marketing study, clinical data of patients treated with Freedom Total Knee System was retrieved from the clinical records after approval from the Institutional Ethics Committee . All the patients above the age of 18 years who completed at least three years after TKR were observed for the study purpose. Patients treated for OA were included while the patients who received the implant for treatment of rheumatoid arthritis and traumatic injury were excluded. Factors such as aseptic loosening, implant failure, and need for revision surgery were observed to evaluate implant performance. Cases were recruited for clinical assessment of primary efficacy endpoint in terms of post-surgery maximun range of motion. Secondary efficacy endpoint was to determine the clinical and social quality of life as per the American Knee Society Score (AKSS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain and stiffness scores. RESULTS: A total of 158 patients who had 191 TKR were observed for performance. The mean age of the patients was 67.67 years; mean BMI was 28.97±3.33, and the group comprised of 43% men and 57% women. Telephonic follow up at three years of 158 patients identified that none of them required revision surgery or had aseptic loosening suggesting excellent performance. Final clinical follow up at three years was available for only 35 patients (41 knee implants). The range of motion significantly improved from preoperative 104°±5.67° (range, 85°-119°) to 119.8°±11.05° (98°-123°) at follow-up (p<0.05). There was a significant improvement in clinical and functional AKSS score and WOMAC score at follow-up. CONCLUSION: The evaluation of Freedom Total Knee System for TKR in treating OA, at a minimum of three years follow up showed excellent outcomes in terms of performance, range of motion, reduced postoperative stiffness and pain, and improved functionality.
Gastroenteritis In Pregnancy: Relevance and Remedy.
Mehta S, Khatuja R, Verma M … +1 more , Grover A
J Clin Diagn Res · 2017 Sep · PMID 29207791 · Full text
Abstract loading — click title to view on PubMed.
Large Vulvar Haematoma of Traumatic Origin.
Papoutsis D, Haefner HK
J Clin Diagn Res · 2017 Sep · PMID 29207790 · Full text
Abstract loading — click title to view on PubMed.
Minerals in Pregnancy and Lactation: A Review Article.
Khayat S, Fanaei H, Ghanbarzehi A
J Clin Diagn Res · 2017 Sep · PMID 29207789 · Full text
Micronutrients (include vitamins and minerals) are essential for normal function, growth and development. Minerals have important effects on the health of the mother and foetus. But biological mechanisms of minerals are...
Micronutrients (include vitamins and minerals) are essential for normal function, growth and development. Minerals have important effects on the health of the mother and foetus. But biological mechanisms of minerals are not completely understood. Micronutrient deficiency during pregnancy can lead to anaemia, hypertension, obstetric complications and even maternal death and in foetus lead to a fail in growth and development. Mineral deficiency during pregnancy, particularly exist in developing countries. During pregnancy due to the increased demands caused by physiological changes, deficiency is exaggerated and as a result its complications occur. Thus, ensuring to receive enough macronutrients and micronutrients before and during pregnancy, is important. Nevertheless, there are controversies regarding administrating supplements. There are not enough studies about some of the minerals and the challenges remain. Regarding the importance of minerals in pregnancy and lactation, in this review we will analyze the role of them in pregnancy and lactation.
Hyperparathyroidism during Pregnancy- A Diagnostic and Therapeutic Challenge.
Sharma R, Bhanupriya, Bhartiya V … +2 more , Guleria K, Suneja A
J Clin Diagn Res · 2017 Sep · PMID 29207788 · Full text
Primary Hyperparathyroidism (PHP) is a rare event in pregnancy; Maternal complications in PHP patients can be as high as 67%. It can be overlooked easily because of many similar complaints shared by hyperparathyroidism a...
Primary Hyperparathyroidism (PHP) is a rare event in pregnancy; Maternal complications in PHP patients can be as high as 67%. It can be overlooked easily because of many similar complaints shared by hyperparathyroidism and pregnancy such as nausea and vomiting, gastritis, bone aches, easy fatigability. Hypercalcemic crisis can develop resulting in coma and death. Neonatal effects are tetany and death in about 80% of cases. We report a case, of an antenatal woman at 30 weeks gestation with complains of painful swelling in left lower jaw and below right knee, pain over right hip joint and frequent episodes of gastritis. She was finally diagnosed to have primary hyperparathyroidism and brown tumour due to parathyroid adenoma. The baby was kept in Neonatal Intensive Care Unit (NICU) for three weeks, in view of prematurity with respiratory distress and later developed sepsis with DIC. The patient's signs and symptoms regressed after parathyroid surgery and the baby was healthy at the time of discharge. This case highlights the progressive deterioration of the patient because of lack of awareness of this disease process and its impact on maternal and foetal morbidity.
About
- Frequency
- Sun
- Papers found
- 200
- RSS feed
- Subscribe