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Annals Of Internal Medicine[JOURNAL]

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In acute or subacute LBP at risk for chronicity, supported self-management reduced disability vs. medical care over 1 y.

Selinger S, ACP Journal Club Editorial Team at McMaster University

Ann Intern Med · 2026 May · PMID 42081818 · Publisher ↗

GIM/FP/GP:[Formula: see text] Phys Med & Rehab:[Formula: see text]. GIM/FP/GP:[Formula: see text] Phys Med & Rehab:[Formula: see text].

Amputation Rates Among Opioid-Related Hospitalizations in the United States, 2016 to 2022.

Karandinos G, Montero F, Chang Y … +3 more , Baggett TP, Unick J, Ciccarone D

Ann Intern Med · 2026 Jun · PMID 42081817 · Full text

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Q&A: Weight versus fat versus muscle loss.

Melillo G

Ann Intern Med · 2026 May · PMID 42081816 · Publisher ↗

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In cardiology outpatients at high stroke risk, smartwatch-based screening vs. usual care increased detection of new onset AF at 180 d.

Lip GYH, ACP Journal Club Editorial Team at McMaster University

Ann Intern Med · 2026 May · PMID 42081815 · Publisher ↗

GIM/FP/GP:[Formula: see text] Cardiology:[Formula: see text] Geriatrics:[Formula: see text]. GIM/FP/GP:[Formula: see text] Cardiology:[Formula: see text] Geriatrics:[Formula: see text].

In postmenopausal women at high risk for fracture, romosozumab for 3 mo was noninferior to 12 mo for increasing total hip BMD at 1 y.

Huang YQ, Watt J, ACP Journal Club Editorial Team at McMaster University

Ann Intern Med · 2026 May · PMID 42081814 · Publisher ↗

Geriatrics:[Formula: see text] Rheumatology:[Formula: see text]. Geriatrics:[Formula: see text] Rheumatology:[Formula: see text].

In uncomplicated acute appendicitis, initial antibiotic therapy vs. appendectomy had a lower cumulative complication rate at 10 y.

Bobrovitz N, Lang E, ACP Journal Club Editorial Team at McMaster University

Ann Intern Med · 2026 May · PMID 42081813 · Publisher ↗

Emergency Med:[Formula: see text] GIM/FP/GP:[Formula: see text] Infectious Disease:[Formula: see text]. Emergency Med:[Formula: see text] GIM/FP/GP:[Formula: see text] Infectious Disease:[Formula: see text].

Tenecteplase 4.5 to 24 h after non-LVO stroke with potentially salvageable brain tissue improved functional outcomes at 90 d.

Lo B, ACP Journal Club Editorial Team at McMaster University

Ann Intern Med · 2026 May · PMID 42081812 · Publisher ↗

Emergency Med:[Formula: see text] GIM/FP/GP:[Formula: see text] Neurology:[Formula: see text]. Emergency Med:[Formula: see text] GIM/FP/GP:[Formula: see text] Neurology:[Formula: see text].

Annals Video Summary - Effectiveness and Tolerability of Pharmacologic Prophylaxis for Chronic Migraine.

Ann Intern Med · 2026 Jun · PMID 42081811 · Publisher ↗

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Annals On Call - Clinical Mastery in Primary Care.

Centor RM, Kravitz RL

Ann Intern Med · 2026 May · PMID 42081810 · Publisher ↗

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In critically ill adults, accuracy of pulse oximeters for detecting hypoxemia varied by skin tone.

Donato AA, Reddy R, ACP Journal Club Editorial Team at McMaster University

Ann Intern Med · 2026 May · PMID 42081809 · Publisher ↗

GIM/FP/GP:[Formula: see text] Critical Care:[Formula: see text] Pulmonology:[Formula: see text]. GIM/FP/GP:[Formula: see text] Critical Care:[Formula: see text] Pulmonology:[Formula: see text].

In acute ischemic stroke, adding minocycline to standard care increased excellent functional outcome rates at 90 d.

Alberts MJ, ACP Journal Club Editorial Team at McMaster University

Ann Intern Med · 2026 May · PMID 42081808 · Publisher ↗

GIM/FP/GP:[Formula: see text] Neurology:[Formula: see text]. GIM/FP/GP:[Formula: see text] Neurology:[Formula: see text].

In patients receiving benzodiazepines long-term, a web-based education and tapering tool improved cessation vs. usual care.

Leung LB, ACP Journal Club Editorial Team at McMaster University

Ann Intern Med · 2026 May · PMID 42081807 · Publisher ↗

Mental Health:[Formula: see text] GIM/FP/GP:[Formula: see text]. Mental Health:[Formula: see text] GIM/FP/GP:[Formula: see text].

Summary for Patients: Pharmacologic Prophylaxis for Chronic Migraine.

Ann Intern Med · 2026 Jun · PMID 42081806 · Publisher ↗

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In adults with T2D and ASCVD, tirzepatide was noninferior to dulaglutide for a composite CV outcome at a median 4 y.

Karagiannis T, Avgerinos I, Tsapas A … +1 more , ACP Journal Club Editorial Team at McMaster University

Ann Intern Med · 2026 May · PMID 42081805 · Publisher ↗

GIM/FP/GP:[Formula: see text] Cardiology:[Formula: see text] Endocrinology:[Formula: see text]. GIM/FP/GP:[Formula: see text] Cardiology:[Formula: see text] Endocrinology:[Formula: see text].

Correction: Iron Deficiency Anemia.

Ann Intern Med · 2026 Apr · PMID 42044507 · Publisher ↗

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Q&A: ACP focuses on appropriate screening for breast cancer.

Kearney-Strouse J

Ann Intern Med · 2026 Jun · PMID 42044506 · Publisher ↗

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Annals Graphic Medicine - Cranial Nerve VII.

Kunju AT

Ann Intern Med · 2026 May · PMID 42044505 · Publisher ↗

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"Never More Than 15 Feet From the Respirator": Housestaff Research During the 1955 Boston Polio Epidemic.

Cotton D

Ann Intern Med · 2026 Jun · PMID 42044503 · Publisher ↗

In July 1955, a devastating polio epidemic struck Massachusetts only 3 months after the licensing of the Salk vaccine. One of the last major polio epidemics in the United States, it overwhelmed the local health care syst... In July 1955, a devastating polio epidemic struck Massachusetts only 3 months after the licensing of the Salk vaccine. One of the last major polio epidemics in the United States, it overwhelmed the local health care system. At Massachusetts General Hospital, 2 assistant residents-the equivalent of today's postgraduate year 2 trainees-were assigned to oversee a hastily organized polio ward and a rising second-year medical student was charged with setting up and running an adjoining laboratory. There, they and other residents conducted original patient-oriented research while providing round-the-clock care for patients, most in iron lungs, under crisis conditions. Their work was facilitated by a strong preexisting culture of bedside research at the hospital. Extremely long work hours ensured constant, close patient observation. A lack of role boundaries between the physician as researcher and as clinician and an absence of formal requirements for patient consent to research in that era also facilitated the studies, which were of similar methodological sophistication and ethical consideration to contemporaneous studies of other diseases. There is evidence that this experience influenced their subsequent careers. The autonomy granted these trainees contrasts sharply with the restricted roles permitted to medical students and residents during the initial surge of the recent COVID-19 pandemic.

A Glimpse of the Divine.

Mills-Robertson K

Ann Intern Med · 2026 Apr · PMID 42008818 · Publisher ↗

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