Journal Der Deutschen Dermatologischen Gesellschaft = Journal Of The German Society Of Dermatology[JOURNAL]

BACKGROUND AND OBJECTIVES: Recent studies have suggested potential links between dermatological conditions, dyslipidemia, and cardiovascular health, yet the relationship between serum lipids and rosacea remains uncertain... BACKGROUND AND OBJECTIVES: Recent studies have suggested potential links between dermatological conditions, dyslipidemia, and cardiovascular health, yet the relationship between serum lipids and rosacea remains uncertain. PATIENTS AND METHODS: Utilizing data from UK Biobank, we employed Cox proportional hazard models to evaluate the correlation between rosacea and serum lipids, with mediation analysis further elucidating the underlying mechanisms. Additionally, two-sample Mendelian randomization and linkage disequilibrium score regression were performed to determine the genetic association. RESULTS: In both the blood biochemistry cohort and the nuclear magnetic resonance metabolome cohort, higher levels of total cholesterol, LDL, and cholesterol in large LDL were inversely associated with rosacea (HR = 0.90 [0.85-0.95], 0.91 [0.86-0.96], and 0.90 [0.85-0.95], respectively). Additionally, omega-3 was found to potentially reduce the risk of rosacea by increasing cholesterol levels in large LDL (OR = 0.88 [0.82-0.94]; mediated proportion = 61.56%). Mendelian randomization analyses further supported the protective effects of total cholesterol and cholesterol in large LDL against rosacea (OR = 0.70 [0.55-0.89] and 0.79 [0.62-0.99], respectively). CONCLUSIONS: These findings suggest that higher levels of total cholesterol and cholesterol in large LDL may decrease rosacea risk, while omega-3 could influence rosacea pathogenesis through modulation of cholesterol in large LDL.

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Anifrolumab Treatment in Cutaneous Lupus Erythematosus with and without systemic involvement: A Retrospective Study.

Bosch-Amate X, Corbella-Bagot L, Ayguasanosa M … +8 more , Giavedoni P, Araujo O, Espinosa G, Cervera R, Gómez-Puerta JA, Aróstegui JI, Mensa-Vilaro A, Mascaró JM

J Dtsch Dermatol Ges · 2026 Jun · PMID 41691405 · Publisher ↗

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Continuous Glucose Monitor Failure Following Exposure to High-Output LED-Based Photography.

Ocker-Serger L, Abu Rached N, Ahmed K … +2 more , Frost C, Bechara FG

J Dtsch Dermatol Ges · 2026 Feb · PMID 41691404 · Publisher ↗

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Novel Clinical and Histological Insights into Cutaneous Kikuchi-Fujimoto Disease and Kikuchi Disease-Like Inflammatory Pattern (KLIP).

Brufau-Cochs M, Bosch-Amate X, Gil-Lianes J … +5 more , de Anta NC, Iranzo P, Giavedoni P, García-Herrera A, Mascaró JM

J Dtsch Dermatol Ges · 2026 Feb · PMID 41670591 · Publisher ↗

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Dramatic rescue of calcium chloride extravasation using hyaluronidase injection.

Yu WT, Chen TL

J Dtsch Dermatol Ges · 2026 Feb · PMID 41656793 · Publisher ↗

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A wolf in sheep's clothing - a chronically progressive toe tumor.

Farmer K, Zolotas M, Dilling A … +3 more , Ghoreschi F, Ghoreschi K, Humme D

J Dtsch Dermatol Ges · 2026 Jun · PMID 41652939 · Publisher ↗

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Widespread non-blanching eruption in a female patient with recent fever on immunosuppressive therapy.

Busana L, Cedirian S, Brunetti T … +3 more , Misciali C, Piraccini BM, Pileri A

J Dtsch Dermatol Ges · 2026 May · PMID 41652934 · Publisher ↗

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Real-world use of anifrolumab in refractory cutaneous lupus: case series and review of the literature.

Martínez-Sernández V, Martínez-Fernández S, Peón-Currás G … +3 more , Fernández-Aguado S, Cervantes-Pérez EC, Abalde-Pintos MT

J Dtsch Dermatol Ges · 2026 May · PMID 41645607 · Publisher ↗

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Pore-guided needle insertion: a simple technique to reduce pain during local anesthesia.

Cerci FB, Scaburi IR, Nadir U … +1 more , Tolkachjov SN

J Dtsch Dermatol Ges · 2026 Jun · PMID 41645462 · Full text

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S3 Guideline for the Treatment of Psoriasis vulgaris, adapted from EuroGuiDerm - part 2: Specific clinical and comorbid situations.

Nast A, Altenburg A, Augustin M … +23 more , Bachmann F, Boehncke WH, Cornberg M, Geerdes-Fenge H, Häcker B, Härle P, Klaus J, Köhm M, Köllner A, Mrowietz U, Ockenfels HM, Pennitz A, Philipp S, Richter T, Rosenbach T, Schaberg T, Schlaeger M, Schmid-Ott G, Sebastian M, Thölken K, von Kiedrowski R, Willuhn U, Zeyen C

J Dtsch Dermatol Ges · 2026 Feb · PMID 41641952 · Full text

The present Part 2 of the updated German S3 guideline on the treatment of psoriasis vulgaris provides recommendations for therapy selection in special clinical situations and in the presence of comorbidities. A major foc... The present Part 2 of the updated German S3 guideline on the treatment of psoriasis vulgaris provides recommendations for therapy selection in special clinical situations and in the presence of comorbidities. A major focus of this update is the chapter on screening for tuberculosis as well as therapy selection and management in latent tuberculosis. The recommendations regarding the use of interferon-gamma release assays and the indication for chest radiography have been extensively revised. In addition, the guidance on the suitability of systemic psoriasis therapies in patients with latent tuberculosis and on the need for preventive antituberculous treatment has been thoroughly updated. In the chapter on inflammatory bowel diseases, risankizumab and guselkumab have been added as recommended treatment options, as both agents have recently been approved for the indications Crohn's disease and ulcerative colitis. Further substantial revisions are included in the chapters on patients with a history of malignancy and viral hepatitis.

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Chemotherapy-induced alopecia: an exploratory questionnaire-based study from Israel comparing knowledge, attitudes, and management practices among dermatologists and oncologists.

Lyakhovitsky A, Segal O, Vizan E … +7 more , Dotan A, Kassem R, Lyakhovitsky K, Shemer A, Kaplan B, Galili E, Barzilai A

J Dtsch Dermatol Ges · 2026 Jun · PMID 41635958 · Full text

BACKGROUND AND OBJECTIVES: Chemotherapy-induced alopecia, encompassing both acute reversible alopecia and its persistent form, significantly impacts patients' quality of life but remains inadequately addressed. This stud... BACKGROUND AND OBJECTIVES: Chemotherapy-induced alopecia, encompassing both acute reversible alopecia and its persistent form, significantly impacts patients' quality of life but remains inadequately addressed. This study aimed to compare dermatologists' and oncologists' knowledge, attitudes, and practices regarding chemotherapy-induced alopecia, as well as their awareness of scalp cooling as a preventive intervention. PATIENTS AND METHODS: A cross-sectional survey was conducted in Israel at nine tertiary medical centers using a structured questionnaire to assess knowledge, attitudes, and practices related to chemotherapy-induced alopecia, including separately analyzed persistent chemotherapy-induced alopecia and scalp cooling. Responses from dermatologists and oncologists were compared, and factors influencing knowledge scores were identified. RESULTS: Both groups demonstrated limited knowledge. Oncologists scored higher on acute chemotherapy-induced alopecia (mean 3.88 vs. 2.74, p < 0.001), while dermatologists tended to score higher on persistent chemotherapy-induced alopecia (mean 7.85 vs. 6.92, p = 0.063). Male participants scored lower than female participants (p = 0.050). Oncologists were more familiar with scalp cooling, citing cost and logistical issues as significant barriers; dermatologists emphasized the need for proactive care and education. CONCLUSIONS: Significant knowledge gaps and differing practices between dermatologists and oncologists underscore the importance of targeted educational initiatives and interdisciplinary collaboration to improve patient care.

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A large erythematous plaque of the scalp.

Brunetti T, Ricci C, Bardazzi F … +2 more , Fiorentino M, La Placa M

J Dtsch Dermatol Ges · 2026 May · PMID 41627942 · Publisher ↗

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Mycosis Fungoides Palmaris et Plantaris Mimicking Palmoplantar Pustulosis: A rare case report.

Wang J, Wen X, Wan R … +2 more , Liu J, Wang L

J Dtsch Dermatol Ges · 2026 Feb · PMID 41622821 · Publisher ↗

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Journal Der Deutschen Dermatologischen Gesellschaft = Journal Of The German Society Of Dermatology[JOURNAL]

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