Tijdschrift Voor Diergeneeskunde[JOURNAL]

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[Better evidence based decision making].

Haneveld JK

Tijdschr Diergeneeskd · 2013 Aug · PMID 23977811

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[Why Giardia is so hard to eradicate].

Bosje JT, Nijsse ER, Overgaauw PA

Tijdschr Diergeneeskd · 2013 Aug · PMID 23977810

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A previously unknown mechanism in viral pathogenesis leading to effective new vaccines and post-exposure immune treatments of viral infections.

Bijlenga G

Tijdschr Diergeneeskd · 2013 Aug · PMID 23977809

Investigations with the rabies virus identified a previously unknown mechanism of viral pathogenesis. After ultracentrifugation of a suspension of rabid dog brain and rabies vaccine strains, the supernatant was found to... Investigations with the rabies virus identified a previously unknown mechanism of viral pathogenesis. After ultracentrifugation of a suspension of rabid dog brain and rabies vaccine strains, the supernatant was found to contain active components, as evaluated in an in vitro plaque test. The unexpected detection of active components in non-sedimented material prompted further research and the finding that these components, and not the complete virus, were responsible for paralysis and death. Vaccination of cattle with existing rabies vaccines showed that even low titres of antibodies against these components provided protection after challenge. In a control group of non-vaccinated cows, cows that had low titres of these antibodies survived rabies challenge. These low titres could not be detected with the usual serum neutralization test in mice but only with a plaque reduction test, which is more sensitive. A hyperimmune serum raised in rabbits against active components isolated from the brain of a rabid dog was injected intracerebrally into mice that had been previously injected intramuscularly with a rabies virus. This delayed post-exposure treatment was still effective against advanced rabies (virus already in the brain, but not yet paralytic symptoms). This promising finding makes the development of a new inactivated rabies vaccine possible and opens the way for post-exposure treatment for humans, particularly in developing countries where rabies is still a major problem. The role of these active components in other viral diseases, such as human immunodeficiency virus, should be investigated.

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[Opinions about the veterinary business guidance of yes-or-no managed dairy farms].

Steeneveld W, Vink MC, Derks M … +1 more , Hogeveen H

Tijdschr Diergeneeskd · 2013 Aug · PMID 23977808

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[Trends from the GD-monitoring].

Holzhauer M, Geudeke T, Kense M

Tijdschr Diergeneeskd · 2013 Aug · PMID 23977807

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[VvAA starts MBA for health professionals].

De Moor W

Tijdschr Diergeneeskd · 2013 Aug · PMID 23977806

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[Pulling on a ...].

Boissevain I

Tijdschr Diergeneeskd · 2013 Aug · PMID 23977805

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[Wageningen and Utrecht as natural partners].

Leneman M, Vrieselaar H

Tijdschr Diergeneeskd · 2013 Aug · PMID 23977804

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[Don't sit on the farmer's lap].

Swormink BK

Tijdschr Diergeneeskd · 2013 Jul · PMID 23923662

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[Professor Arie Brand, vision and development. Interview by Andries van Foreest and Ko Minderhoud].

Brand A

Tijdschr Diergeneeskd · 2013 Jul · PMID 23923661

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[Watch out with travel to Spain].

Haneveld JK

Tijdschr Diergeneeskd · 2013 Jul · PMID 23923660

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[Intravenous cytostatic agent applicable to veterinary medicine].

Van Geijlswijk I

Tijdschr Diergeneeskd · 2013 Jul · PMID 23923659

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[Almost all chicks positive for ESBL's].

Haneveld JK

Tijdschr Diergeneeskd · 2013 Jul · PMID 23923658

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[The history of rabies in animals in the Netherlands].

De Rosa M, Stenvers OF, Smak JA

Tijdschr Diergeneeskd · 2013 Jul · PMID 23923657

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Improvement of technical results following use of Ingelvac CircoFLEX in a Dutch organic breeding and fattening farm: a case report.

Schlepers M, Gelauf J, Wertenbroek N … +1 more , Nielen M

Tijdschr Diergeneeskd · 2013 Jul · PMID 23923656

Porcine Circovirus type 2 (PCV2) is a ubiquitous infection and major cause of production loss for the pig industry. The aim of this study was to evaluate the effect of vaccination against PCV2 on technical results of pig... Porcine Circovirus type 2 (PCV2) is a ubiquitous infection and major cause of production loss for the pig industry. The aim of this study was to evaluate the effect of vaccination against PCV2 on technical results of pigs on an organic breeding and fattening farm, focussing on growth and mortality of weaned piglets and fattening pigs. The study was based on retrospective data between January 2009 and May 2011. During the study period, three subsequent vaccination strategies were used: 1. Stellamune One, 2. Stellamune One+CircoFLEX, 3. MycoFLEX+CircoFLEX. From these three periods, the corresponding management- and slaughterhouse data were analysed by an ANOVA-test. Due to few data in period 2 and an outbreak of Actinobacillus pleuropneumoniae during periods 2 and 3, these two periods were combined in one period and analysed by a two-sample t-test. Mortality of weaned piglets decreased with 3.6% (0.6 - 6.6%) (P0.023) in comparison to period 1 and average daily weight gain improved by 21 gram (7 - 34 gram) (P0.004) in periods 2 and 3. Mortality of fattening pigs was 2.3% (1.2 - 3.5%) (P0.001) less than in period 1 and corrected energy conversion rate improved 0.27 (0.05 - 0.49) (P0.017). There was no significant effect on slaughterhouse parameters. In conclusion, vaccination against PCV2 improved technical results of weaned and fattening pigs on this farm. The advantage of vaccination with MycoFLEX+CircoFLEX instead of Stellamune One+CircoFLEX is that the two FLEX-vaccines can be mixed and administered as a one shot vaccine, reducing work load and animal stressors.

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