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Evidence-based Complementary And Alternative Medicine[JOURNAL]

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Antimalarial Properties of L. Leaf Extract in Mice: Survivability Depends Less on Parasitaemia Suppression.

Ansong S, Nkrumah D, Nketia RI … +4 more , Bekoe SO, Brobbey AA, Asante-Kwatia E, Komlaga G

Evid Based Complement Alternat Med · 2023 · PMID 38161788 · Full text

has been used to treat malaria in Ghana albeit without scientific evidence of antimalarial activity and safety. This work aimed to assess the antimalarial properties and acute toxicity of the aqueous leaf extract of in... has been used to treat malaria in Ghana albeit without scientific evidence of antimalarial activity and safety. This work aimed to assess the antimalarial properties and acute toxicity of the aqueous leaf extract of in murine models. Aqueous extract of the plant was analysed for both suppressive and curative antimalarial properties in chloroquine-sensitive ANKA strains of rodent -infected mice. Acute toxicity evaluation was performed in rats according to the OECD 425 guidelines. The extract displayed antiplasmodial activity with ED of 117.49 ± 15.22 mg/kg and 144.84 ± 18.17 mg/kg in suppressive and curative studies, respectively. The highest % parasitaemia suppression exerted was 76.90 ± 0.64% and 61.50 ± 0.97%, respectively, in the suppressive and curative studies. Survival of infected mice treated with the extract was significantly prolonged. This was dependent on the dose of the extract but imperfectly related to the % parasitaemia suppression. Related antimalarial parameters including percentage hematocrit, changes in body weight, and temperature of experimental mice indicated alleviation of malarial symptoms of treated animals. The extract did not show toxicity in rats. L. has antimalarial properties, and was safe. It suppressed parasitaemia in both suppressive and curative studies, was not toxic to animals and prolonged the life of infected animals under treatment. This, therefore, justifies the traditional use of for the treatment of malaria in Ghana.
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Retracted: A Novel Immune-Associated Gene Signature for Overall Survival Prediction in Patients with Oral Squamous Cell Carcinoma.

And Alternative Medicine EC

Evid Based Complement Alternat Med · 2023 · PMID 38125198 · Full text

[This retracts the article DOI: 10.1155/2022/1063130.]. [This retracts the article DOI: 10.1155/2022/1063130.].
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Retracted: Efficacy of Oxymatrine Plus Antiviral in the Treatment of Sepsis and Its Effect on the Levels of Endotoxin and Inflammatory Factors.

And Alternative Medicine EC

Evid Based Complement Alternat Med · 2023 · PMID 38125197 · Full text

[This retracts the article DOI: 10.1155/2022/1938325.]. [This retracts the article DOI: 10.1155/2022/1938325.].
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Retracted: Effects of Warm Needle Acupuncture plus Xitong Waixi Lotion in Patients with Knee Osteoarthritis: A Randomized Controlled Trial.

And Alternative Medicine EC

Evid Based Complement Alternat Med · 2023 · PMID 38125196 · Full text

[This retracts the article DOI: 10.1155/2022/5467712.]. [This retracts the article DOI: 10.1155/2022/5467712.].
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Retracted: Efficacy of Triple Viable Enteric-Coated Capsules Combined with Enteral Nutrition on Patients with Chronic Critical Illness and Influence on Immune and Coagulation Function.

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Evid Based Complement Alternat Med · 2023 · PMID 38125195 · Full text

[This retracts the article DOI: 10.1155/2021/3718255.]. [This retracts the article DOI: 10.1155/2021/3718255.].
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Retracted: Effects of Early Weight-Bearing Treadmill Training Combined with Pre-Emptive Analgesia on Femoral Fracture Recovery.

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Evid Based Complement Alternat Med · 2023 · PMID 38125194 · Full text

[This retracts the article DOI: 10.1155/2023/8498062.]. [This retracts the article DOI: 10.1155/2023/8498062.].
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Retracted: Improved Cardiac Function and Attenuated Inflammatory Response by Additional Administration of Tirofiban during PCI for ST-Segment Elevation Myocardial Infarction Patients.

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Evid Based Complement Alternat Med · 2023 · PMID 38125193 · Full text

[This retracts the article DOI: 10.1155/2021/8371996.]. [This retracts the article DOI: 10.1155/2021/8371996.].
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Retracted: Relationship between the Degree of Illness in Elderly Patients with Rheumatoid Arthritis and Parameters of Musculoskeletal Ultrasound and Oswestry Dysfunction Index and Clinical Value Analysis.

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Evid Based Complement Alternat Med · 2023 · PMID 38125192 · Full text

[This retracts the article DOI: 10.1155/2022/4307864.]. [This retracts the article DOI: 10.1155/2022/4307864.].
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Retracted: SERPINE1 Gene Is a Reliable Molecular Marker for the Early Diagnosis of Aortic Dissection.

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Evid Based Complement Alternat Med · 2023 · PMID 38125191 · Full text

[This retracts the article DOI: 10.1155/2022/5433868.]. [This retracts the article DOI: 10.1155/2022/5433868.].
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Retracted: Genus and Its Waste Utilization: A Review on Health-Promoting Activities and Industrial Application.

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Evid Based Complement Alternat Med · 2023 · PMID 38125190 · Full text

[This retracts the article DOI: 10.1155/2021/2488804.]. [This retracts the article DOI: 10.1155/2021/2488804.].
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Retracted: Clinical Observation of Reduning Combined with Recombinant Human Interferon -2b in the Treatment of Children with Viral Pneumonia.

And Alternative Medicine EC

Evid Based Complement Alternat Med · 2023 · PMID 38125189 · Full text

[This retracts the article DOI: 10.1155/2022/1739561.]. [This retracts the article DOI: 10.1155/2022/1739561.].
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Retracted: Changes of Intestinal Flora and Lymphocyte Subsets in Patients with Chronic Renal Failure.

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Evid Based Complement Alternat Med · 2023 · PMID 38125188 · Full text

[This retracts the article DOI: 10.1155/2021/4288739.]. [This retracts the article DOI: 10.1155/2021/4288739.].
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Retracted: Serum sTREM-1 and CXCL-16 Levels in Children with Pneumonia and Their Diagnostic Value.

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Evid Based Complement Alternat Med · 2023 · PMID 38125187 · Full text

[This retracts the article DOI: 10.1155/2021/7179796.]. [This retracts the article DOI: 10.1155/2021/7179796.].
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Retracted: Effect of Alteplase Thrombolysis on Coagulation Function and Nerve Function of Patients with Ischemic Stroke.

And Alternative Medicine EC

Evid Based Complement Alternat Med · 2023 · PMID 38125186 · Full text

[This retracts the article DOI: 10.1155/2022/9440271.]. [This retracts the article DOI: 10.1155/2022/9440271.].
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Retracted: Carnosol Attenuates LPS-Induced Inflammation of Cardiomyoblasts by Inhibiting NF-B: A Mechanistic and Study.

And Alternative Medicine EC

Evid Based Complement Alternat Med · 2023 · PMID 38125185 · Full text

[This retracts the article DOI: 10.1155/2022/7969422.]. [This retracts the article DOI: 10.1155/2022/7969422.].
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Retracted: Effects of the Wenyang Zhenshuai Granule on the Expression of LncRNA-MiR143HG/miR-143 Regulating ERK5 in H9C2 Cardiomyocytes.

And Alternative Medicine EC

Evid Based Complement Alternat Med · 2023 · PMID 38125184 · Full text

[This retracts the article DOI: 10.1155/2021/6431007.]. [This retracts the article DOI: 10.1155/2021/6431007.].
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Retracted: Repetitive Transcranial Magnetic Stimulation Improves Neuropathy and Oxidative Stress Levels in Rats with Experimental Cerebral Infarction through the Nrf2 Signaling Pathway.

And Alternative Medicine EC

Evid Based Complement Alternat Med · 2023 · PMID 38125183 · Full text

[This retracts the article DOI: 10.1155/2021/3908677.]. [This retracts the article DOI: 10.1155/2021/3908677.].
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Retracted: Clinical Efficacy of Osimertinib in Patients with Advanced Non-Small Cell Lung Cancer and Its Effect on Serum CEA and VEGF Expression.

And Alternative Medicine EC

Evid Based Complement Alternat Med · 2023 · PMID 38125182 · Full text

[This retracts the article DOI: 10.1155/2022/3032087.]. [This retracts the article DOI: 10.1155/2022/3032087.].
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Retracted: Efficacy of Methylprednisolone plus Azithromycin in the Treatment of RMPP and Its Effect on the Changes of T Lymphocyte Subsets.

And Alternative Medicine EC

Evid Based Complement Alternat Med · 2023 · PMID 38125181 · Full text

[This retracts the article DOI: 10.1155/2022/1833195.]. [This retracts the article DOI: 10.1155/2022/1833195.].
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Retracted: Decoction in the Treatment of Diabetic Constipation and Its Influence on the Intestinal Environment and the Incidence of Adverse Reactions: A Randomized Trial.

And Alternative Medicine EC

Evid Based Complement Alternat Med · 2023 · PMID 38125180 · Full text

[This retracts the article DOI: 10.1155/2022/5373765.]. [This retracts the article DOI: 10.1155/2022/5373765.].
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