BMC Surgery[JOURNAL]
Sun
200 papers
Five-year trends in proctological practice in Dubai: Insights from a high-volume referral centre.
Soomar SM, Aranha LR, Jan Muhammad BE … +1 more , Al Hosein M
BMC Surg · 2026 Jun · PMID 42304352 · Full text
BACKGROUND: Proctological diseases are common worldwide, yet their true burden is often underestimated due to delayed presentation and limited standardized reporting with a diverse population, rising case numbers, and ev...
BACKGROUND: Proctological diseases are common worldwide, yet their true burden is often underestimated due to delayed presentation and limited standardized reporting with a diverse population, rising case numbers, and evolving minimally invasive techniques. Understanding local trends is essential for improving the quality of care. This study aims to evaluate five-year trends in proctologic surgical procedures, patient characteristics, and referral patterns in a tertiary referral centre in Dubai. METHODS: This retrospective trend analysis study reviewed all patients who underwent proctological surgeries at a tertiary hospital in Dubai from July 2020 to June 2025. Demographic data, case characteristics, procedure types, and operative details were extracted from electronic records. Trends were summarized as frequency and percentages, and Poisson regression was used to assess associations between patients' characteristics and procedure patterns, considering a p-value ≤ 0.05 significant. RESULTS: A total of 967 patients underwent proctological surgeries during the five years. The mean age was 41.5 years, and most patients were male. Hemorrhoid procedure was the most common (42%), followed by anal fistula and abscess-related surgeries. More than half of the cases were identified as minor, while 159 (16.44%) were major. Most cases were classified as elective (856, 88.52%). Yearly trends showed a rise in the rate of hemorrhoid and fistula surgeries. Men have a significantly higher relative likelihood of surgery compared to women, by 23% [aRR: 1.23, 95% CI: 1.08-1.41]. The relative risk of no incision was more than twice that of a clean wound class [aRR: 2.14, 95% CI: 1.72-2.66]. CONCLUSION: This study reports that age and gender remain significant contributors to the high risk of proctology surgeries. Males are predominantly at higher relative likelihood of surgery. The trends show that hemorrhoids were the common problem for which almost half of the patients underwent surgery. Despite advancements in minimally invasive surgical techniques. Challenges such as high recurrence rates. This study highlights the need for a standardized approach in proctology to enhance patient outcomes and streamline treatment processes.
Robot-assisted sacroiliac screw fixation for tile type C posterior pelvic ring injuries: a comparative study.
Luo B, Huang Y, Wu Y … +1 more , Xu S
BMC Surg · 2026 Jun · PMID 42304348 · Full text
OBJECTIVE: To compare the clinical efficacy and safety of robot-assisted versus conventional fluoroscopy-guided percutaneous sacroiliac screw fixation for Tile type C posterior pelvic ring injuries. METHODS: A retrospect...
OBJECTIVE: To compare the clinical efficacy and safety of robot-assisted versus conventional fluoroscopy-guided percutaneous sacroiliac screw fixation for Tile type C posterior pelvic ring injuries. METHODS: A retrospective analysis was conducted on 60 patients with Tile type C posterior pelvic ring injuries treated at our institution from January 2021 to December 2023. Patients were stratified into two groups based on surgical technique: a robot-assisted group (n = 31, TiRobot-assisted percutaneous sacroiliac screw fixation) and a conventional group (n = 29, C-arm fluoroscopy-guided percutaneous sacroiliac screw fixation). Group allocation reflected the surgical pathway available during the study period rather than randomisation. The following parameters were compared between groups: operative time, intraoperative fluoroscopy frequency, intraoperative blood loss, screw placement accuracy, number of guide-wire adjustments, fracture healing time, complications, and Majeed scores at final follow-up. RESULTS: All patients completed 12-24 months of follow-up (mean 15.6 months). No significant difference in operative time was observed between the robot-assisted group (78.5 ± 15.2 min) and the conventional group (82.3 ± 18.6 min) (P > 0.05). The robot-assisted group demonstrated significantly fewer intraoperative fluoroscopy exposures (8.2 ± 2.1 vs. 18.6 ± 4.5, P < 0.001), fewer guide-wire adjustments (1.3 ± 0.6 vs. 4.2 ± 1.8, P < 0.001), and less intraoperative blood loss (45.2 ± 12.8 mL vs. 68.5 ± 18.3 mL, P < 0.001). The excellent-and-good screw placement rate was 97.96% (48/49) in the robot-assisted group versus 86.36% (38/44) in the conventional group (P = 0.042). No significant difference was found in fracture healing time. Majeed functional scores at final follow-up were higher in the robot-assisted group (85.6 ± 8.2) than in the conventional group (81.2 ± 9.5) (P = 0.049). No severe complications occurred in the robot-assisted group, whereas one case of L5 nerve-root irritation associated with screw malposition occurred in the conventional group. CONCLUSION: For Tile type C posterior pelvic ring injuries, robot-assisted percutaneous sacroiliac screw fixation was associated with higher screw placement accuracy, lower intraoperative radiation exposure, fewer guide-wire adjustments, reduced blood loss, and favourable early functional outcomes compared with conventional fluoroscopy-guided fixation. These findings, derived from a single-centre retrospective cohort, should be interpreted as hypothesis-generating and warrant confirmation in prospective multicentre studies.
Predicting PPOI secondary to laparoscopic radical resection of rectal cancer combined with lobaplatin hyperthermic intraperitoneal chemotherapy: a multi-center study.
Zhang W, Che B, Yang N … +10 more , Cheng F, Xu Q, Li Y, Xie J, Gao C, Yang Z, Ma D, Zhang T, Ba Z, Zhang W
BMC Surg · 2026 Jun · PMID 42304336 · Full text
PURPOSE: PPOI is one of the common complications of intraperitoneal hyperthermic chemotherapy during laparoscopic radical resection of rectal cancer, which seriously affects the prognosis of patients. The purpose of this...
PURPOSE: PPOI is one of the common complications of intraperitoneal hyperthermic chemotherapy during laparoscopic radical resection of rectal cancer, which seriously affects the prognosis of patients. The purpose of this study is to establish a prediction system for PPOI secondary to laparoscopic radical resection of rectal cancer combined with intraperitoneal hyperthermic chemotherapy with lobaplatin. MATERIALS AND METHODS: Retrospectively analyzed the clinical data of 800 patients who received laparoscopic radical rectal cancer combined with lobaplatin hyperthermia and intraperitoneal chemotherapy in three Level 3 Grade A hospitals from June 1, 2014, to June 1, 2024, and determined the predictive factors through univariate, multivariate, and Lasso regression analysis. We employ eight ML algorithms, Logistic Regression (LR), Decision Tree (DT), Random Forest (RF), Extreme gradient boosting (XGB), Support Vector Machine (SVM), Multilayer Perceptron (MLP), K-Nearest Neighbor (KNN), Gaussian Naive Bayes (GNB), to train and develop ML models using a 10x cross-validation method. The performance of the model was evaluated by a variety of indicators, including the area under the receiver operating characteristic curve (ROC), calibration curve, decision curve, PR curve, and confusion matrix. In addition, model interpretation is performed through Shapley Additive Interpretation (SHAP) analysis to clarify the importance of each feature of the model and its basis for decision-making. RESULTS: We identified six key predictors, including Surgical bleeding, Duration of surgery, HB, WBC, ALB and adhesiolysis, and built a prediction model based on these factors. The sensitivity, specificity, positive predictive value, and negative predictive value of different models were compared. All eight models showed good predictive performance and stability, with the RF model being the optimal model. Finally, we developed a web-based calculator based on the optimal model. CONCLUSIONS: These predictors and models were able to assess the potential for PPOI following laparoscopic radical curative rectal cancer combined with lobaplatin hyperthermic intraperitoneal chemotherapy. Early alerts can be provided in a clinical setting, helping medical professionals make informed judgments and select the most appropriate treatment strategy (https://zw17786325639.shinyapps.io/ppoi/).
Evaluation of the E-PASS, mE-PASS, and POSSUM scoring systems for predicting postoperative complications following radical nephrectomy.
Uysal U, Alma E, Altunkol A … +6 more , Anıl H, Karkin K, Özbilen MH, Akçor CT, Kök YE, Aksay B
BMC Surg · 2026 Jun · PMID 42304320 · Full text
BACKGROUND: Accurate prediction of postoperative complications following radical nephrectomy is of great clinical importance for perioperative risk stratification and patient management. Although several scoring systems...
BACKGROUND: Accurate prediction of postoperative complications following radical nephrectomy is of great clinical importance for perioperative risk stratification and patient management. Although several scoring systems are used in urological surgery, there is no widely accepted, procedure-specific risk assessment tool. This study aimed to evaluate the performance of the Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM), Estimation of Physiologic Ability and Surgical Stress (E-PASS), and its modified version (mE-PASS) in predicting postoperative complications after radical nephrectomy. As a secondary objective, the association between modified Glasgow Prognostic Score (mGPS), Prognostic Nutritional Index (PNI), and neutrophil-to-lymphocyte ratio (NLR), which reflect systemic inflammation and nutritional status, and postoperative complications was also investigated. MATERIALS AND METHODS: A total of 148 patients who underwent radical nephrectomy for renal tumors at our institution between January 2022 and March 2025 were retrospectively analyzed. Patients were divided into two groups based on the presence of postoperative complications. Postoperative complications were assessed according to the Clavien-Dindo classification, and complications of grade ≥ 2 were included in the analysis. Demographic characteristics, comorbidities, preoperative laboratory parameters, surgical variables, and postoperative outcomes were recorded. The predictive performance of the scoring systems was evaluated using the area under the receiver operating characteristic (ROC) curve (AUC). RESULTS: Postoperative complications were observed in 51 patients (34.5%). The POSSUM score demonstrated the highest predictive performance with an AUC of 0.810, showing high sensitivity (82.4%) and specificity (71.1%). The E-PASS score was also statistically significant but exhibited a more limited predictive performance (AUC: 0.682). In contrast, the mE-PASS score showed markedly lower predictive ability (AUC: 0.599). Patients who developed complications had significantly lower PNI values and higher NLR values (p < 0.05). Additionally, intraoperative blood loss, tumor size, and length of hospital stay were significantly greater in the complication group (p < 0.05). CONCLUSION: POSSUM and E-PASS may serve as useful tools for predicting postoperative complications following radical nephrectomy. However, given their moderate predictive performance and the limitations of the present study, these findings should be validated in larger, prospective, multicenter studies.
Warm staple-line irrigation (37-40 °C) before omentopexy reduces early bleeding after laparoscopic sleeve gastrectomy: a prospective, randomized trial.
Abdalla GM, Farrag AM, Halim GM
BMC Surg · 2026 Jun · PMID 42304298 · Full text
BACKGROUND: Early bleeding remains a common concern after laparoscopic sleeve gastrectomy (LSG), despite improvements in stapling technology and reinforcement techniques. This study examined whether using warm saline to...
BACKGROUND: Early bleeding remains a common concern after laparoscopic sleeve gastrectomy (LSG), despite improvements in stapling technology and reinforcement techniques. This study examined whether using warm saline to irrigate the staple line before performing omentopexy could enhance intra-operative hemostasis and reduce early postoperative bleeding. METHODS: In this prospective randomized trial conducted between December 2024 and June 2025, 200 adults undergoing primary LSG were allocated equally to warm saline irrigation (37-40 °C) or conventional room-temperature irrigation (22-24 °C), reflecting two clinically relevant intraoperative strategies in routine laparoscopic practice. Irrigation was applied directly to the staple line, followed by complete suctioning, careful inspection, and standardized omentopexy using 2-0 PDS sutures spaced 2 cm apart. The primary endpoint was a 48-h composite of early postoperative bleeding, defined as clinical bleeding, need for endoscopic or surgical control, hemoglobin drop (ΔHb) ≥ 2 g/dL on postoperative day 1, or drain output ≥ 150 mL in the first 24 h. Secondary outcomes included hemostasis time, ΔHb, drain volume, pain scores, postoperative nausea and vomiting (PONV), length of stay (LOS), and 30-day complications. This trial was powered for a composite bleeding endpoint rather than rare major bleeding events. RESULTS: Baseline characteristics were similar between groups. The composite bleeding endpoint occurred in 5% of patients receiving warm irrigation versus 15% in the control group (p = 0.02). Warm irrigation also resulted in lower drain output (82 ± 31 vs 128 ± 46 mL; p < 0.001) and a smaller ΔHb drop (1.28 ± 0.52 vs 2.06 ± 0.61 g/dL; p < 0.001). Pain scores were modestly lower at 24 h. LOS, PONV, readmission rates, and leak rates were comparable. CONCLUSION: Warm saline irrigation may improve hemostasis and early bleeding-related outcomes after LSG. However, given the composite nature of the primary endpoint and the limited sample size for rare complications, these findings should be interpreted cautiously, and larger multicenter studies are needed for confirmation. TRIAL REGISTRATION: ClinicalTrials.gov (NCT07475169), retrospectively registered on 12 February 2026.
Differential changes in longitudinal and area-based right ventricular function after aortic surgery: an exploratory echocardiographic study.
Akkaya BB, Sert DE, Yiğitbaşı MM … +5 more , Gül EB, Yılmaz A, Akdi M, Karahan M, Mavioglu HL
BMC Surg · 2026 Jun · PMID 42298550 · Full text
BACKGROUND: Reductions in right ventricular (RV) longitudinal parameters, particularly tricuspid annular plane systolic excursion (TAPSE), are frequently observed after cardiac surgery. However, postoperative changes in...
BACKGROUND: Reductions in right ventricular (RV) longitudinal parameters, particularly tricuspid annular plane systolic excursion (TAPSE), are frequently observed after cardiac surgery. However, postoperative changes in longitudinal RV motion may not occur in parallel with other conventional echocardiographic indices of RV function. This study aimed to evaluate early postoperative changes in longitudinal and area-based RV functional parameters after elective aortic surgery. METHODS: This single-center retrospective study included 102 patients undergoing elective aortic surgery. Preoperative and early postoperative transthoracic echocardiography was used to assess RV function, including TAPSE, fractional area change (FAC), and tissue Doppler-derived S' velocity. Absolute and relative percentage changes in RV echocardiographic parameters were calculated. To summarize the relative behavior of longitudinal and area-based RV indices, the Right Ventricular Functional Dissociation Index (RV-FDI) was calculated as the ratio of postoperative-to-preoperative FAC to postoperative-to-preoperative TAPSE. RV-FDI was considered an exploratory descriptive ratio and not a validated diagnostic or prognostic marker. RESULTS: TAPSE decreased significantly from 22.0 ± 4.9 mm to 18.3 ± 5.9 mm (p < 0.001). FAC also decreased significantly from 41.9 ± 6.9% to 36.9 ± 7.3% (p < 0.001), and S' velocity declined from 14.9 ± 3.0 cm/s to 12.6 ± 3.5 cm/s (p < 0.001). The relative reduction in TAPSE was significantly greater than that in FAC (- 17.8 ± 12.3% vs. -12.2 ± 6.3%, p = 0.00027), indicating non-uniform postoperative changes among conventional RV echocardiographic parameters. Mean RV-FDI was 1.09 ± 0.16. No significant differences in postoperative RV parameters or RV-FDI were observed between sternotomy and minimally invasive approaches. RV-FDI was not significantly associated with postoperative lactate levels, inotropic support, mechanical ventilation duration, ICU stay, or hospital stay. CONCLUSION: Elective aortic surgery was associated with a greater early postoperative reduction in longitudinal RV indices than in FAC, suggesting that conventional echocardiographic parameters of RV function may not change uniformly after surgery. RV-FDI may provide a simple exploratory description of this relative pattern, but it should not be interpreted as a validated measure of RV mechanics, clinical RV dysfunction, or prognosis. Further studies incorporating RV strain, three-dimensional echocardiography, RV-pulmonary arterial coupling, and longitudinal clinical outcomes are required to clarify the physiological and prognostic significance of these findings.
Thoracolithiasis: a rare and frequently underrecognized entity - a retrospective single-center study and narrative literature review.
İşevi C, Pirzirenli MG, Öten BC … +3 more , Kolcu H, Çelik B, Büyükkarabacak Y
BMC Surg · 2026 Jun · PMID 42298547 · Full text
OBJECTIVES: Thoracolithiasis is a rare benign pleural condition classically described as a freely mobile, calcified intrapleural loose body. Systematic data on non-mobile thoracolithiasis and its clinical context are sca...
OBJECTIVES: Thoracolithiasis is a rare benign pleural condition classically described as a freely mobile, calcified intrapleural loose body. Systematic data on non-mobile thoracolithiasis and its clinical context are scarce. This study aimed to characterize the clinical, radiologic, etiologic, and geographic features of non-mobile thoracolithiasis, to explore isolated versus secondary forms, and to identify scenarios in which these lesions mimic malignant pleural nodules. MATERIALS AND METHODS: This retrospective, observational study included adult patients diagnosed with thoracolithiasis at a tertiary thoracic surgery center between January 2010 and December 2024. Eligible cases had radiologic and/or surgical confirmation and complete clinical and imaging data. Demographic, clinical, radiologic, and surgical variables, including asbestos exposure and coexisting thoracic disease, were collected. Patients were stratified by sex, symptom status, calcification, and isolated versus secondary thoracolithiasis. Statistical comparisons used the Mann-Whitney U test and Chi-square or Fisher's exact test (two-tailed p < 0.05). A narrative review of the literature was conducted to contextualize the findings of the present cohort. RESULTS: Twenty patients with pathologically confirmed thoracolithiasis (mean age 64.0 ± 10.5 years; 70% male; 75% with a smoking history) were included. No lesion showed evidence of mobility on available imaging review or intraoperative assessment. 60% of lesions were non-calcified, with a mean maximum diameter of 29.4 ± 17.8 mm. Thoracolithiasis coexisted with lung cancer in 40% and with other thoracic disease in 30%; 30% were isolated. Patients with calcified lesions were older than those with non-calcified lesions (70.0 vs. 60.0 years, p = 0.023). Lung cancer occurred exclusively in older male smokers and was significantly associated with male sex (p = 0.010) and smoking history (p = 0.027). Isolated thoracolithiasis was more frequent in female non-smokers, and all isolated cases underwent diagnostic exploration (100% vs. 35.7%, p = 0.025). Asbestos-exposed patients (25%) originated exclusively from inland provinces, whereas most non-exposed patients resided in a coastal, non-asbestos-endemic region. CONCLUSION: Non-mobile thoracolithiasis exhibits two clinically distinct patterns: a secondary type in older male smokers with thoracic malignancy, and an isolated type in non-smoking women without additional thoracic disease. Non-mobile, often non-calcified thoracoliths in low-risk patients frequently mimic malignant pleural nodules and may lead to avoidable thoracoscopic or open exploration. Recognizing this broader spectrum of thoracolithiasis may help refine diagnostic algorithms and reduce unnecessary invasive procedures.
da Vinci single-port versus da Vinci Xi multiport robot-assisted radical prostatectomy for localized prostate cancer: a GRADE-assessed systematic review and meta-analysis.
Mirza W, Aslam MB, Ammar M … +3 more , Ali RN, Moeen-Ud-Din MB, Hadhoud AM
BMC Surg · 2026 Jun · PMID 42298538 · Full text
BACKGROUND: The adoption of the da Vinci single-port (SP) platform for robot-assisted radical prostatectomy (RARP) has expanded; however, comparative evidence versus the da Vinci Xi multiport system remains heterogeneous...
BACKGROUND: The adoption of the da Vinci single-port (SP) platform for robot-assisted radical prostatectomy (RARP) has expanded; however, comparative evidence versus the da Vinci Xi multiport system remains heterogeneous across access corridors and perioperative pathways. We performed a GRADE-assessed systematic review and meta-analysis to quantify platform-level differences in oncologic surrogates, perioperative recovery, and early functional outcomes. METHODS: This systematic review and meta-analysis was prospectively registered in PROSPERO (CRD420261299189). We systematically searched MEDLINE (via PubMed), Embase, Scopus, Web of Science, the Cochrane Central Register of Controlled Trials (CENTRAL), and ClinicalTrials.gov from inception to the final date of February 1, 2026. Eligible studies were comparative cohorts (prospective or retrospective, including propensity-matched designs) of adult patients with localized prostate cancer undergoing da Vinci SP RARP compared directly with da Vinci Xi multiport RARP. Studies were required to report at least one extractable perioperative, oncologic, or functional outcome measure. Outcomes were pooled using random effect models. The risk of bias was assessed using ROBINS-I, and the certainty of evidence was appraised using GRADE. No external funding was received for this study. RESULTS: Five comparative cohorts were included, comprising 968 patients who underwent SP-RARP and 668 patients who underwent Xi or multiport RARP. The positive surgical margin rates were not significantly different between the approaches (RR 0.90, 95% CI 0.75-1.09; I²=0%). Operative time was longer with SP (MD 10.39 min, 95% CI 0.72-20.07; I²=88%), whereas estimated blood loss (MD - 68.95 mL, 95% CI - 128.27 to - 9.63; I²=98%) and length of hospital stay (MD - 17.01 h, 95% CI - 24.12 to - 9.89 h; I²=91%) favored SP. Lymph node dissection rates (RR 0.49, 95% CI 0.20-1.23; I²=99%), postoperative complications (RR 1.06, 95% CI 0.71-1.60; I²=0%), and urinary continence at ~ 3 months (RR 1.22, 95% CI 0.87-1.71; I²=92%) were not significantly different between the two groups. Corridor-based subgrouping did not modify the PSM effects (p for subgroup differences = 0.51). The certainty of evidence ranged from low to very low, limited by non-randomized designs and inconsistencies for several recovery endpoints. CONCLUSIONS: Based on low-to very-low-certainty evidence from five nonrandomized cohorts, SP-RARP showed similar margin control and complication risk to Xi/multiport RARP, with a directional recovery signal favoring SP for blood loss and hospital stay; however, these estimates carried extreme heterogeneity (I²=98% and 91%) and should be regarded as exploratory. No strong platform-level recommendations can be made without prospective confirmatory evidence.
Evaluation and prevalence of associated anomalies in children with anorectal malformations at a tertiary referral center.
Maadani M, Ashjaei B, Raji H … +2 more , Bahroudi M, Moghtaderi M
BMC Surg · 2026 Jun · PMID 42298523 · Full text
BACKGROUND: Anorectal malformations (ARMs) comprise a spectrum of congenital anomalies frequently associated with multisystem congenital defects. Early recognition of associated anomalies is essential for appropriate sur...
BACKGROUND: Anorectal malformations (ARMs) comprise a spectrum of congenital anomalies frequently associated with multisystem congenital defects. Early recognition of associated anomalies is essential for appropriate surgical planning and long-term management. This study aimed to investigate the prevalence of associated anomalies with ARMs in the Children's Tertiary Center. MATERIALS AND METHODS: This retrospective cross-sectional study included all children diagnosed with ARM who were admitted to the Children's Medical Center Hospital between 2020 and 2022. Associated anomalies were categorized by organ system and by syndromic patterns, including VACTERL association. Data were extracted from medical records. Descriptive statistics were used, and associations with sex and gestational age were analyzed using Chi-square or Fisher's exact tests. RESULTS: Fifty-seven children with ARM were included (52.6% male). Associated anomalies were detected in 73.7% of patients. The most common associated anomalies involved the cardiovascular (52.6%), genitourinary (36.8%), and vertebral (24.6%) systems. No significant association was found between gestational age and the prevalence of anomalies. Female sex was associated with a higher prevalence of cardiac anomalies. CONCLUSION: Associated anomalies are highly prevalent in children with ARM, particularly affecting the cardiovascular, genitourinary, and vertebral systems. Systematic screening and multidisciplinary management are essential to reduce morbidity and improve long-term outcomes.
Efficacy of chlorhexidine in alcohol versus aqueous povidone-iodine for preoperative skin antisepsis in preventing surgical site infections: a systematic review and meta-analysis with trial sequential analysis.
Zhu L, Han Z, Wen K … +3 more , Zhang L, Tang J, Chen X
BMC Surg · 2026 Jun · PMID 42298517 · Full text
BACKGROUND: Surgical site infections represent a prevalent postoperative complication, significantly impacting patient safety and increasing the burden on healthcare resources. As a key measure for preventing these infec...
BACKGROUND: Surgical site infections represent a prevalent postoperative complication, significantly impacting patient safety and increasing the burden on healthcare resources. As a key measure for preventing these infections, preoperative skin antisepsis plays a crucial role. However, current meta-analyses and international guidelines have yet to reach a unified agreement on the optimal type and concentration of antiseptic preparation. This study aims to compare the efficacy of chlorhexidine in alcohol and aqueous povidone-iodine in preventing surgical site infections through systematic review and meta-analysis. METHODS: A systematic search was conducted in PubMed, Embase, Cochrane Library, and Web of Science databases for randomized controlled trials (RCTs) comparing the preoperative skin antisepsis effects of chlorhexidine in alcohol and aqueous povidone-iodine up to May 31, 2025. The primary outcome was the incidence of surgical site infections, while secondary outcomes included adverse events. Subgroup analyses were conducted according to chlorhexidine concentration, wound classification, and surgical category. The meta-analysis was conducted using R software, with a statistical threshold of P < 0.05 for significance. To evaluate the robustness of the findings, sensitivity analysis and trial sequential analysis (TSA) were conducted. RESULTS: The meta-analysis included 17 RCTs involving 13,737 patients. The results revealed that chlorhexidine in alcohol was significantly more effective than aqueous povidone-iodine in preventing surgical site infections (RR = 0.84, 95% CI: 0.73-0.95, P < 0.01; I² = 14%). Subgroup analyses further demonstrated that 2.0%-2.5% chlorhexidine in alcohol (RR = 0.83, 95% CI: 0.71-0.97, P = 0.02; I² = 32%) was associated with a lower SSI risk than aqueous povidone-iodine. Furthermore, in non-clean surgery (RR = 0.85, 95% CI: 0.75-0.97, P = 0.01; I² = 0%) and general surgery (RR = 0.70, 95% CI: 0.53-0.92, P = 0.01; I² = 65%), chlorhexidine in alcohol was associated with a significantly lower SSI risk. Sensitivity analyses showed consistent results across individual studies, and TSA suggested that the accumulated evidence has reached the required information size. However, the interpretation of subgroup findings should consider residual heterogeneity in some subgroups and the risk of bias of included trials. CONCLUSION: Compared with aqueous povidone-iodine, chlorhexidine in alcohol was associated with a lower risk of surgical site infections, particularly in non-clean surgery and at chlorhexidine concentrations of 2.0%-2.5%.
Clinical and radiological outcomes of unilateral biportal endoscopy and percutaneous endoscopic interlaminar discectomy for highly downward-migrated lumbar disc herniation: a retrospective study.
Liu H, Zhang S, Zhang K … +2 more , Zhou J, Qian C
BMC Surg · 2026 Jun · PMID 42289698 · Full text
PURPOSE: To compare the clinical efficacy and safety of unilateral biportal endoscopy (UBE) versus percutaneous endoscopic interlaminar discectomy (PEID) in the treatment of highly downward-migrated lumbar disc herniatio...
PURPOSE: To compare the clinical efficacy and safety of unilateral biportal endoscopy (UBE) versus percutaneous endoscopic interlaminar discectomy (PEID) in the treatment of highly downward-migrated lumbar disc herniation (HDM-LDH). METHOD: A retrospective study included 61 patients with HDM-LDH, comprising 27 in the UBE group and 34 in the PEID group. All patients followed up for 12 months. Compare differences in general information between the two groups. By analysing and comparing perioperative indicators, MacNab excellent/good rate, complication, and clinical and radiographic outcomes between the two groups. RESULTS: There were no significant differences between the two groups in general information (P > 0.05). The UBE group had a shorter operation time (OT), greater intraoperative blood loss (IBL) and longer postoperative hospital stay (PHS) than the PEID group (P < 0.05). There was no significant difference of MacNab and complications between the two groups (P > 0.05). The visual analogue scale (VAS) - Back at 3 days postoperative in the UBE group was higher than PEID group (P < 0.05). There were no significant differences between the two groups in VAS-Leg and Oswestry disability index scores (P>0.05). There were no significant differences between the two groups in intervertebral disc height (P>0.05). The cross-sectional area of the spinal canal (CASC) and cross-sectional area of the dural sac (CADS) in the UBE group were more significant than PEID group postoperative, and the cross-sectional area of the paraspinal muscles (CAPM) in the UBE group decreased more than PEID group postoperative (P < 0.05). The UBE group had a lower residual area of nucleus pulposus (RANP), a higher area of laminectomy (AL) and a lower preservation rate of facet joints (PRFJ) compared to the PEID group (P < 0.05). CONCLUSION: UBE yields higher AL, lower PRFJ, larger IBL and longer PHS compared with PEID. It also leads to more severe short-term postoperative low back pain and paraspinal muscle injury. Nevertheless, UBE possesses better surgical efficiency and shorter OT. It can better restore CASC and CADS, and reduce RANP simultaneously. In clinical practice, the surgical approach for HDM-LDH should be selected according to surgeon experience and individualized treatment strategies.
Comparison of the efficacy of posterior lumbar interbody fusion and transforaminal lumbar interbody fusion in the treatment of double-level lumbar spondylolisthesis combined with spinal stenosis: a retrospective comparative study.
Ma Z, Luan H, Abulimiti K … +5 more , Xie X, Tao J, Yang J, Sheng W, Deng Q
BMC Surg · 2026 Jun · PMID 42289686 · Full text
OBJECTIVE: To compare the clinical and radiographic outcomes of posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) in the treatment of double-level lumbar spondylolisthesis combine...
OBJECTIVE: To compare the clinical and radiographic outcomes of posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) in the treatment of double-level lumbar spondylolisthesis combined with spinal stenosis. METHODS: This retrospective comparative study included 44 patients with double-level lumbar spondylolisthesis combined with spinal stenosis who underwent surgical treatment between April 2013 and August 2021. Patients were divided into PLIF and TLIF groups. Perioperative parameters, complications, and clinical outcomes, including visual analog scale (VAS) scores for back and leg pain and the Oswestry Disability Index (ODI), were evaluated preoperatively and at 1 week, 6 months, 12 months, and 24 months postoperatively. Radiographic parameters related to sagittal alignment and vertebral slippage were also assessed. Statistical analyses were performed using appropriate parametric or non-parametric tests based on data distribution. RESULTS: Baseline characteristics were comparable between the two groups (P > 0.05). No major intraoperative complications or implant-related failures were observed. Both groups demonstrated significant improvements in VAS scores and ODI at all postoperative time points compared with preoperative values (P < 0.05), with no significant differences between groups (P > 0.05). Radiographic parameters showed significant postoperative improvement in both groups (P < 0.05). Although the TLIF group demonstrated numerically greater improvements in certain sagittal alignment parameters, these differences did not reach statistical significance. CONCLUSION: Both PLIF and TLIF are effective surgical options for the treatment of double-level lumbar spondylolisthesis combined with spinal stenosis, resulting in significant clinical and radiographic improvement. No significant differences in clinical outcomes were observed between the two techniques. While TLIF may show a trend toward improved restoration of certain sagittal alignment parameters, these findings should be interpreted with caution.
Correction: Serum sodium as an adjunct marker of acute appendici-tis severity: a retrospective cohort study.
Messias B, Cubas I, Oliveira C … +5 more , Hashimoto F, Mocchetti E, Ichinose T, Waisberg J, Junior MAFR
BMC Surg · 2026 Jun · PMID 42289677 · Full text
Abstract loading — click title to view on PubMed.
Factors influencing surgical residents attrition: a mixed-methods study from a low-middle-income country.
Tariq R, Siddiqui NA, Khan SA … +3 more , Khan M, Siddiqui D, Islam S
BMC Surg · 2026 Jun · PMID 42288842 · Full text
OBJECTIVE: Premature loss of residents prior to completion of training, is common among surgical specialties, negatively impacts other trainees and program leadership, and disrupts the continuity of care. Developing coun...
OBJECTIVE: Premature loss of residents prior to completion of training, is common among surgical specialties, negatively impacts other trainees and program leadership, and disrupts the continuity of care. Developing countries face various challanges which may impact this attrition, however, there is a lack of literature on the rate of resident attrition in low-middle-income countries (LMICs). We aimed to identify the rates and predictors of surgical residents' attrition at a single institution. METHODOLOGY: We conducted a mixed-methods observational study; single center retrospective review and prospective survey including quantitative and qualitative analyses of trainees who left prior to completion of training. Data regarding gender, marital status, locality, year of training, surgical specialty, and reasons for attrition were collected. The trainees were then contacted for a follow-up survey to assess their reasons as well as pathways after leaving, opinions about the program, program director, relationship with peers, and their satisfaction with the decision. RESULTS: Between 2005 and 2024, 617 surgical residents were enrolled, of whom 51.0% (n=315) completed training, 30.5% (n=188) left before completion (attrition), and 18.5% were still in training. Gender and geographic background (local vs. non-local) were not associated; however, marital status significantly influenced attrition, with singles more likely to drop out (60.5% vs. 34.3% among graduates (p<0.001). Most departures occurred in the first year (54.3%; n=102) particularly in pediatric surgery (62.2%; n=23/37) and general surgery (44.1%; n=57/129). At exit interviews, the most common reasons included family commitments (34.2%), personal reasons (9.6%), and better job opportunities (9.5%). A follow-up survey of 59 former residents revealed that 61% (n=36) switched to another program in the same specialty, while 30.5% (n=18) changed specialties. Despite moderate satisfaction with training (3.07/5) and program leadership (3.14/5), respondents reported high satisfaction with their decision to leave (4.31/5). Main concerns included unprofessional behavior (30.5%), toxic work environments (20.3%), and excessive workload (16.9%). CONCLUSION: Surgical resident attrition at our center was high, particularly in the early years of training and in certain specialties, with marital status emerging as a significant predictor. Efforts at reducing reasons for attrition are critical for the future.
Does exposing all parathyroids during total thyroidectomy with central lymph node dissection protect long-term function? A prospective cohort study.
Jin X, Xu Z, Wen L … +6 more , Chen X, Chen S, Huang H, Wang W, Teng L, Yu X
BMC Surg · 2026 Jun · PMID 42288820 · Full text
BACKGROUND: Hypoparathyroidism (HypoPT) is the most common complication after total thyroidectomy (TT) and central lymph node dissection (CLND) for thyroid carcinoma. However, there's still no effective surgical strategy...
BACKGROUND: Hypoparathyroidism (HypoPT) is the most common complication after total thyroidectomy (TT) and central lymph node dissection (CLND) for thyroid carcinoma. However, there's still no effective surgical strategy to prevent its incidence. This study evaluated the impact of sufficient intraoperative exposure of the parathyroid glands (PG) on postoperative parathyroid function, the rate of parathyroid autotransplantation, and incidental parathyroidectomy. METHODS: Prospective data from 133 consecutive patients who underwent TT and CLND by a single surgeon at the First Affiliated Hospital of Zhejiang University School of Medicine were systematically collected. All patients were categorized into sufficient exposure (exposed) group and insufficient exposure (control) group based on whether all 4 PGs were identified during surgery. PG exposure and autotransplantation were recorded intraoperatively, while incidental parathyroidectomy was determined via routine pathology reports. Postoperative parathyroid hormone (PTH) levels, serum calcium levels, and hypocalcemia-related symptoms (limb numbness/tetany) were monitored for at least six months. Continuous variables were compared using independent samples t-test for normally distributed data., while categorical variables were analyzed using Pearson's chi-square test. A two-sided P-value < 0.05 was considered statistically significant. RESULTS: No patients in the sufficient exposure group developed permanent hypoPT, while 2 patients in the insufficient exposure group exhibited biochemical hypoPT. Mean PTH levels were significantly higher in the sufficient exposure group (33.22 ± 16.48 pg/ml vs. 26.48 ± 10.94 pg/ml, P = 0.048) within six months. Parathyroid autotransplantation was more frequent in the sufficient exposure group (26.0% vs. 8.3%, P = 0.008). For transient hypoPT, incidental parathyroidectomy or clinical symptoms, there was no significant difference between groups (P > 0.05). CONCLUSION: Sufficient exposure of the PGs during surgery can potentially protect parathyroid function in terms of PTH level without increasing transient hypoPT, indicating PG sufficient exposure is a practical way to protect parathyroid function.
Clinical and injury-related factors associated with specific postoperative complications after surgical treatment of distal radius fractures: a retrospective observational study.
Yuan M, Ma X, Xu Z
BMC Surg · 2026 Jun · PMID 42286548 · Full text
BACKGROUND: With an ageing population and increased physical activity, distal radius fractures (DRF) are relatively common. Surgical treatment is becoming increasingly prevalent, yet postoperative complications including...
BACKGROUND: With an ageing population and increased physical activity, distal radius fractures (DRF) are relatively common. Surgical treatment is becoming increasingly prevalent, yet postoperative complications including complex regional pain syndrome (CRPS), tendon irritation/rupture, carpal tunnel syndrome, internal fixation‑related discomfort, and non‑union/malunion significantly impact functional recovery and quality of life. Identifying associated risk factors is crucial for optimising treatment strategies. OBJECTIVE: To investigate the clinical and injury-related risk factors for specific postoperative complications in patients undergoing surgical treatment for distal radius fractures. METHODS: A retrospective observational study was conducted. Medical records of patients undergoing surgical treatment for DRF at our hospital between January 2022 and June 2025 were collected. Patients were categorised into a complication group and a non-complication group based on the occurrence of specific postoperative complications. Propensity score matching (PSM) was used to balance baseline differences, resulting in 60 cases per group. Primary outcomes comprised the incidence of specific postoperative complications and independent risk factors. Secondary outcomes included wrist range of motion, grip strength, and DASH (Disabilities of the Arm, Shoulder, and Hand) scores at 6 months postoperatively; injury-related factors [AO (Arbeitsgemeinschaft für Osteosynthesefragen) fracture classification, open fracture status, time from injury to surgery]; surgical factors (surgical approach, operative time, use of internal fixation); postoperative complications (diabetes mellitus, osteoporosis); postoperative management (immobilisation duration); and rehabilitation protocols. Univariate and multivariate logistic regression analyses were employed to identify risk factors. RESULTS: After PSM, 60 cases and 60 controls were analysed. Among the 60 cases, the most common complication types were tendon irritation/rupture (31.7%) and internal fixation-related discomfort (23.3%), followed by carpal tunnel syndrome (20.0%) and CRPS (13.3%). Non-union/malunion occurred in 11.7% of cases. These proportions reflect the distribution of complication subtypes within the case group and do not represent population incidence rates. Multivariate analysis revealed that an operative time exceeding 90 min (OR = 4.006, 95% CI: 1.806-3.888) constituted an independent risk factor for postoperative complications (p < 0.05). Analysis of secondary outcomes revealed that the complication group exhibited significantly poorer wrist flexion/extension range of motion, percentage of grip strength recovery, and DASH scores at 6 months postoperatively compared to the non-complication group (p < 0.05). The incidence rates of all three major complications exhibited a significant increasing trend with higher fracture classification grades (p < 0.05). No statistically significant differences were observed between the complication and non-complication groups regarding gender, timing of surgery, approach selection, or type of internal fixation (p > 0.05). CONCLUSION: The occurrence of specific complications following distal radius fracture surgery is closely associated with multiple factors, including surgical technique, injury severity, and postoperative management. The key finding is that operative time > 90 min was strongly associated with complications (OR 4.01), but this association likely reflects underlying case complexity rather than a direct causal effect. Fracture severity (AO-C) and early rehabilitation showed only associative patterns that were either confounded or bidirectional. Thus, the study's primary contribution is to highlight the need for caution in interpreting operative time as a modifiable risk factor without adjusting for complexity, and to identify key unmeasured confounders for future research.
Clinical efficacy and safety of interventional embolization combined with early rehabilitation in the management of post-traumatic shoulder periarthritis.
Su B, Hong Y, Li Z … +5 more , Ouyang S, Yu C, Geng F, Niu J, Peng J
BMC Surg · 2026 Jun · PMID 42286535 · Full text
BACKGROUND: Patients with refractory post-traumatic shoulder periarthritis(PTSP) have markedly reduced quality of life owing to persistent pain and functional restrictions. Thus, exploring a safe, effective treatment reg...
BACKGROUND: Patients with refractory post-traumatic shoulder periarthritis(PTSP) have markedly reduced quality of life owing to persistent pain and functional restrictions. Thus, exploring a safe, effective treatment regimen is essential. AIM: This study compared the efficacy and safety of TAE plus early rehabilitation versus rehabilitation alone for conservatively refractory post-traumatic shoulder periarthritis. METHODS: This study enrolled patients with conservatively refractory post-traumatic shoulder periarthritis admitted between September 2023 and January 2025. Using 1:1 propensity score matching, 60 patients were selected and divided into two groups: the control group (n = 30) received 12 weeks of structured rehabilitation, while the study group (n = 30) received TAE and the same systematic rehabilitation training for 12 weeks from the second day after TAE. Primary outcomes included nocturnal pain (NRS) and Constant-Murley scores; secondary measures were active ROM (forward flexion, external rotation), EQ-5D index, periarticular effusion on MRI, and adverse events. RESULTS: After PSM, the baseline data of the two groups were balanced and comparable (P > 0.05). At all postoperative time points, the study group had notably greater improvements in all indicators than the control group (P < 0.05). At 6 months, its NRS score dropped to 1.8 ± 1.2, significantly lower than the control group's 4.5 ± 1.8 (P < 0.001); Constant-Murley score rose to 86.3 ± 8.7, much higher than the control's 69.8 ± 11.4 (P < 0.001). Forward flexion/external rotation ROM reached 148° ± 18°/75.0° ± 10.3°,significantly better than the control's 132.5° ± 20.1°/62.0° ± 9.8° (P < 0.001); EQ-5D index hit 0.82 ± 0.12, higher than the control's 0.65 ± 0.14 (P < 0.001).MRI showed 89.8% of the study group had effusion reduction/disappearance, versus 52.3% in the control (P < 0.001). No serious adverse events occurred. CONCLUSION: In this exploratory retrospective study, TAE plus early systematic rehabilitation was associated with greater pain relief, improved joint function, and better quality of life compared with rehabilitation alone. These findings are hypothesis-generating and require confirmation in prospective studies.
Transvaginal specimen extraction in laparoscopic surgery for colorectal cancer: a systematic review and meta-analysis.
Hao T, Bo Y, Wuyi W
BMC Surg · 2026 Jun · PMID 42277810 · Full text
BACKGROUND: Natural Orifice Specimen Extraction (NOSE) surgery uses the body's natural orifices as channels for removing surgical specimens. This approach obviates the requirement for an extra incision on the abdominal w...
BACKGROUND: Natural Orifice Specimen Extraction (NOSE) surgery uses the body's natural orifices as channels for removing surgical specimens. This approach obviates the requirement for an extra incision on the abdominal wall, which in turn further enhances the minimally invasive outcome of the surgical procedure. The vagina, which functions as a natural orifice, is widely used to extract specimens that have been surgically resected in the context of laparoscopic colorectal cancer surgery. This study aims to compare postoperative complications, oncological safety, pathological results, and short-term efficacy between transvaginal and transabdominal specimen extraction in laparoscopic colorectal cancer surgery. METHODS: This research adheres to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol. Literature retrieval was conducted in the PubMed/MEDLINE, Web of Science, and EMBASE databases. Clinical data of postoperative complications, pathological results (proximal margin, distal margin, number of lymph nodes), oncological outcomes (DFS and OS), and short-term outcomes (hospital stay, pain score, additional analgesics, flatus time, time to first diet) were collected. Pooled estimates were derived using fixed- and random-effect models. RESULTS: Ultimately, 10 studies with a total of 823 patients were incorporated into the analysis. Compared with the LAP group, the TVSE group tended to have a lower incidence of postoperative complications (OR = 0.45, 95% CI:0.30 ~ 0.67). The pathological findings observed in the TVSE group appear comparable to those in the LAP group, with no apparent discrepancy in the number of retrieved lymph nodes (WMD = 0.54, 95% CI: -0.27 ~ 1.34). No obvious differences were found in disease-free survival (HR = 1.22, 95% CI: 0.72-2.08) and overall survival (HR = 0.76, 95% CI: 0.43-1.37). Compared with the LAP group, the TVSE group may show potential favourable trends in short-term outcomes. CONCLUSIONS: This meta-analysis suggests that the TVSE group may be associated with lower postoperative morbidity and more favorable recovery outcomes than the LAP group. No obvious unfavorable impact on oncological safety was seen in the TVSE group. Due to the observational design of the included studies, relevant conclusions remain inconclusive. More high-quality studies are required to validate these results.
Occult bladder injury in low displacement anterior-posterior compression pelvic fractures type I: a retrospective analysis of incidence and predictors.
Fahmy M, Shawky MA
BMC Surg · 2026 Jun · PMID 42277787 · Full text
BACKGROUND: Pelvic ring injuries are frequently associated with genitourinary trauma, particularly bladder injury, traditionally considered proportional to fracture displacement. Minimally displaced anterior-posterior co...
BACKGROUND: Pelvic ring injuries are frequently associated with genitourinary trauma, particularly bladder injury, traditionally considered proportional to fracture displacement. Minimally displaced anterior-posterior compression (APC I) fractures are often regarded as low risk. However, high-energy trauma may cause significant soft-tissue injury even when skeletal displacement is minimal. This study evaluated the incidence, characteristics, and outcomes of bladder injury in minimally displaced APC I fractures and identified associated risk factors, including dynamic instability. METHODS: We retrospectively reviewed 180 adult patients with APC I fractures undergoing operative fixation after dynamic stress examination under anesthesia confirmed instability, at a high-volume pelvic trauma center (2020-2024). Data included demographics, mechanism of injury, intraoperative findings, bladder injury type, operative parameters, and functional outcomes. Bladder integrity was assessed intraoperatively and repaired primarily by urology. Associations between bladder injury and clinical, radiographic, and biomechanical factors, including pubic diastasis, sacroiliac widening, and pubic rami configuration, were analyzed. RESULTS: Bladder injury occurred in 27 patients (15%), involving the dome (41%), body (37%), or neck (22%). High-energy mechanisms accounted for 95% of injuries, including motor vehicle (47%) and motorcycle (26%) collisions, falls from height (15%), and pedestrian accidents (7%). Female patients had a higher relative incidence (18% vs. 13%, p = 0.04). Bladder injury correlated with longer operative time, increased blood loss, greater dynamic pubic symphyseal diastasis, sacroiliac widening, and high-energy trauma. Pubic rami separation or rotation also signaled increased soft-tissue risk. All injuries were repaired successfully, and functional outcomes were comparable between groups. CONCLUSION: Even minimally displaced APC I fractures may conceal clinically significant bladder trauma, particularly after high-energy mechanisms. Reliance on radiographic displacement alone may underestimate soft-tissue injury risk. Intraoperative vigilance, direct bladder inspection, and timely urologic repair are essential for optimal outcomes. Recognition of this phenomenon can guide risk stratification and improve perioperative management in pelvic trauma. TRIAL REGISTRATION: This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of orthopaedic department of Cairo University (Approval No. [N3032025]).
Prevalence of preoperative sarcopenia according to EWGSOP2 in patients with colorectal cancer and its impact on surgical outcomes: a prospective observational study.
Yılmaz M, Barçin M, Tuna S … +6 more , Koç HB, Bozkurt ME, Aslan G, Özcan C, Bozkurt H, Çolak T
BMC Surg · 2026 Jun · PMID 42277777 · Full text
BACKGROUND: Sarcopenia may adversely affect postoperative outcomes, but most studies in colorectal cancer (CRC) have relied solely on computed tomography (CT)-derived muscle mass. We evaluated the association between a c...
BACKGROUND: Sarcopenia may adversely affect postoperative outcomes, but most studies in colorectal cancer (CRC) have relied solely on computed tomography (CT)-derived muscle mass. We evaluated the association between a comprehensive assessment based on the European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria and short-term postoperative outcomes after curative CRC surgery. METHODS: In this prospective observational study, 70 consecutive patients who underwent curative CRC resection between July 2024 and July 2025 were assessed for muscle strength (handgrip strength), physical performance (4-m gait speed), and muscle mass (L3 CT skeletal muscle index). According to EWGSOP2 criteria, patients were classified as non-sarcopenic or into the hierarchical cumulative stages of probable, confirmed, and severe sarcopenia. Postoperative outcomes included major complications and length of hospital stay. RESULTS: Of the 70 patients, 41 (58.6%) were non-sarcopenic, whereas 29 (41.4%) had at least probable sarcopenia; within this hierarchical group, 27 (38.6%) had confirmed sarcopenia and 18 (25.7%) had severe sarcopenia. Patients with at least probable sarcopenia were older and had lower body mass index and serum albumin levels (all p < 0.01). Across the hierarchical EWGSOP2 stages, the frequency of major postoperative complications increased compared with non-sarcopenic patients (probable 34.4%, confirmed 37.0%, severe 55.5% vs. 9.7%, respectively; p < 0.01), and hospital stay was significantly longer (9.3-10.6 vs. 6.1 days; p < 0.001). Tumor characteristics did not differ significantly between groups. In exploratory multivariable analysis, at least probable sarcopenia was associated with major postoperative complications (adjusted odds ratio [aOR] 11.75, 95% confidence interval [CI] 1.27-108.82; p = 0.030) and prolonged hospital stay (aOR 8.33, 95% CI 1.01-68.38; p = 0.049), although these estimates should be interpreted cautiously because of the small sample size and wide confidence intervals. CONCLUSION: EWGSOP2-based sarcopenia assessment was associated with worse short-term postoperative outcomes after curative CRC resection. Given the limited sample size and wide confidence intervals, these findings should be interpreted as exploratory and require external validation in larger prospective cohorts before clinical implementation. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT06698289.
About
- Frequency
- Sun
- Papers found
- 200
- RSS feed
- Subscribe