Altunay I, Kucukunal A, Demirci GT
… +1 more, Ates B
J Dermatol Case Rep
· 2012 Mar · PMID 22514583
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BACKGROUND: Kaposi sarcoma (KS) is a vascular neoplasm with multicentric cutanenous and extracutaneous involvements, which was first described by Moriz Kaposi in 1872. Since then, different epidemiological clinical and h...BACKGROUND: Kaposi sarcoma (KS) is a vascular neoplasm with multicentric cutanenous and extracutaneous involvements, which was first described by Moriz Kaposi in 1872. Since then, different epidemiological clinical and histopathological variants of this neoplasm have been identified. Classic Kaposi sarcoma (CKS) is one of four main clinico-epidemiologiologic variants. characteristics of the disease. MATERIALS AND METHODS: Four Turkish inpatients with CKS were evaluated in the study. All medical history and clinical data were noted. A screening immunodeficiency workup were performed for all patients. HHV-8 immunofluorescence testing on the specimens and ELISA test for human immunodeficiency virus (HIV 1 and 2) were performed. Pulmonary X ray graphies and computurized tomography (CT) scan were applied. Stage of the tumor was determined, in each case, according to the classification system proposed by Brambilla et al in 2003. RESULTS: All patients are positive for HHV-8. They were all immunocompetent and negative for HIV1 and HIV2. The first patient was unusual for morphological presentation of several verrucoid lesions that was evaluated as verrucoid KS. He was considered stage IB CKS. The patient 2 was a young man and the course of KS seemed unexpectedly aggressive for CKS. His clinical appearence seemed us to be a patient with AIDSassociated KS. The patient was evaluated as stage IVB CKS. Our third patient had also prominent lymphedema associated with bluish discoloration on the toes and fingers, suggesting a diagnosis of peripheral vascular disorder. He was diagnosed as stage IIIB CKS. The fourth case was interesting for very extensive lesions involving big sized plaques and also the existence of mucosal lesion. The patient was diagnosed as stage IVB CKS. CONCLUSIONS: It seems that the reports of exceptional cases of KS are accumulating. Data from various cases should be collected and perhaps, novel clinical classifications should be considered.
J Dermatol Case Rep
· 2012 Mar · PMID 22514582
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BACKGROUND: The propionic acid derivative Benoxaprofen was introduced for the treatment of rheumatic disorders in 1980. Its product license was then withdrawn 2 years later due to concerns over serious dermatologic, hepa...BACKGROUND: The propionic acid derivative Benoxaprofen was introduced for the treatment of rheumatic disorders in 1980. Its product license was then withdrawn 2 years later due to concerns over serious dermatologic, hepatic and renal side effects. Photosensitivity was the most common side effect with reported incidence of up to 50%. MAIN OBSERVATIONS: We present the first case report of a patient who presented with a melanoma diagnosed 27 years after a benoxaprofen-induced photosensitivity reaction. With an estimated 1.5 million patients previously on benoxaprofen, a large number of patients may potentially face increased risk of developing malignant melanoma. This case report can only suggest an association between solar injury secondary to benoxaprofen-related photosensitivity and subsequent melanoma. However the primary factor that improves survival from melanoma is early diagnosis, and so clinicians treating this group of patients should be aware of this risk. CONCLUSION: Although benoxaprofen is no longer in clinical use, the long-term sequelae to its photosensitizing effects may still be clinically important. Clinicians treating this group of patients should be vigilant, and consider a low threshold for diagnostic biopsy of suspicious skin lesions.
Hajar-Serviansky T, Gutierrez-Mendoza D, Galvan IL
… +4 more, Lammoglia-Ordiales L, Mosqueda-Taylor A, Hernandez-Cázares Mde L, Toussaint-Caire S
J Dermatol Case Rep
· 2012 Mar · PMID 22514581
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BACKGROUND: Most patients with oral mucosal melanoma have had a mucosal hyper pigmented area for months or even years before the diagnosis, it is important to consider the differential diagnosis of mucosal melanoma, whic...BACKGROUND: Most patients with oral mucosal melanoma have had a mucosal hyper pigmented area for months or even years before the diagnosis, it is important to consider the differential diagnosis of mucosal melanoma, which in many cases is a difficult diagnosis and because of the aggressive biological behavior of mucosal melanoma it is important to do a quick diagnosis. MAIN OBSERVATION: A 40-year-old Mexican male patient, presented with a lesion on the lower right half of the lip covering almost the entire vermillion border, 1 mm below the white roll. The lesion was a 1.5 x 4 cm pigmented macule with asymmetric and irregular borders and colors. Dermoscopy showed a multi component pattern. An incision biopsy was performed under the impression of mucosal melanoma. The pathologic report described a Clark I vermillion edge mucosal melanoma in situ. CONCLUSIONS: This case had confounding clinical signs that could have misguided the clinician. But dermoscopy proved to be useful when suspecting a malignant lesion, which prompted a biopsy and a correct diagnosis.
Pigatto PD, Berti E, Spadari F
… +2 more, Bombeccari GP, Guzzi G
J Dermatol Case Rep
· 2011 Dec · PMID 22408710
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Exfoliative cheilitis is an uncommon chronic inflammatory condition that generally affects the vermilion of the lips. Its cause is still largely unknown an there is no effective treatment. Here we report of a case of exf...Exfoliative cheilitis is an uncommon chronic inflammatory condition that generally affects the vermilion of the lips. Its cause is still largely unknown an there is no effective treatment. Here we report of a case of exfoliative cheilitis possibly caused by mercury-containing dental amalgam in close proximity to dental titanium implant in a 41-year-old woman. By patch-testing, she was tested positive to thimerosal, palladium, gold, nickel, and copper. There was a strong temporal relation between last titanium dental implant and the onset of exfoliative cheilitis. Clinicians should be aware that exfoliative cheilitis might be associated with an allergy to intraoral dental metals and that titanium dental implant should not be implanted in the vicinity of the mercury-containing dental amalgam filling, even in presence of mercury amalgam as rootend filling material.
Rudnicka L, Olszewska M, Rakowska A
… +1 more, Slowinska M
J Dermatol Case Rep
· 2011 Dec · PMID 22408709
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Trichoscopy performed with a handheld dermoscope or a videodermoscope became an indispensable tool in differential diagnosis of hair and scalp diseases. Current research is focusing on trichoscopy of: 1) non-cicatricial...Trichoscopy performed with a handheld dermoscope or a videodermoscope became an indispensable tool in differential diagnosis of hair and scalp diseases. Current research is focusing on trichoscopy of: 1) non-cicatricial alopecia, 2) cicatricial alopecia, 3) hair shaft disorders, and 4) inflammatory scalp diseases. This review summarizes current knowledge in these four fields of research. In all non-cicatricial alopecias presence of empty follicular openings is a common trichoscopy finding. In alopecia areata black dots and micro-exclamation mark hairs and tapered hairs correlate with disease activity, whereas yellow dots and vellus hairs correlate with disease severity. In androgenic alopecia trichoscopy shows hair shaft thickness heterogeneity, multiple thin and vellus hairs, yellow dots, perifollicular discoloration, and predominance of follicular units with only one hair. These features predominate in the frontal area. In all forms of cicatricial alopecia, trichoscopy shows milky-red or ivory-white areas lacking follicular openings. In classic lichen planopilaris trichoscopy shows perifollicular inflammation, tubular perifollicular scaling, elongated, concentric blood vessels and "classic white dots", which merge to form white areas. Frontal fibrosing alopecia shows mild perifollicular scaling. Folliculitis decalvans is characterized by tufted hairs, large follicular pustules with emerging hair shafts and perifollicular starburst pattern hyperplasia. In dissecting cellulitis characteristic findings are "3D" yellow dots imposed over dystrophic hairs, large, yellow amorphous areas and pinpoint white dots with a whitish halo. Trichoscopy is particularly useful to diagnose hair shaft abnormalities in trichorrhexis nodosa, trichorrhexis invaginata, monilethrix, pili torti, and pili annulati. The method may be also useful in diagnosing inflammatory scalp diseases. In discoid lupus erythematosus trichoscopy shows large arborizing vessels and large hyperkeratotic folliculilar yellow dots. Trichoscopy of scalp psoriasis shows regularly distributed twisted and lacelike blood vessels, whereas in seborroic dermatitis thin arborizing vessels may be observed. In tinea capitis trichoscopy shows comma, corkscrew and zigzag hairs. Examination tinea capitis may be facilitated by UV-light enhanced trichoscopy (UVET). In conclusion, trichoscopy is a non-invasive method which may be applied in differential diagnosis of most hair and scalp diseases.
Bouraoui S, Mlika M, Kort R
… +3 more, Cherif F, Lahmar A, Sabeh M
J Dermatol Case Rep
· 2011 Dec · PMID 22408708
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BACKGROUND: Miliary osteoma cutis (OC) of the face is a rare benign extra skeletal bone formation. For our knowledge, only 23 cases have been reported in the English literature. These lesions may be primary or secondary....BACKGROUND: Miliary osteoma cutis (OC) of the face is a rare benign extra skeletal bone formation. For our knowledge, only 23 cases have been reported in the English literature. These lesions may be primary or secondary. They cause diagnostic, therapeutic and cosmetic concern especially in women who are usually concerned. Our purpose is to present a case which is completely documented with the clinical, histological and radiological findings. We also report a possible pathogenic theory according to our histologic findings. MAIN OBSERVATION: We report a case of a multiple miliary OC of the face in a 45-year-old woman which suffered from gravidarum acne. These lesions were treated by focal surgical treatment. CONCLUSIONS: Based on our histological findings, an osteoblastic metaplasia seems to be a possible pathogenic theory. This metaplasia seems to be secondary to a chronic inflammation. Concerning therapeutic procedures, they are non consensual and debated and are based on surgical or medical treatment. More reports are needed in order to assess the therapeutic management of this disease and its inducing factors.
J Dermatol Case Rep
· 2011 Dec · PMID 22408707
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BACKGROUND: Bullous pemphigoid (BP) is an acquired autoimmune blistering disease mainly affecting the elderly. Recent reports have shown an association with pre-existing neurodegenerative diseases. Triggers including dis...BACKGROUND: Bullous pemphigoid (BP) is an acquired autoimmune blistering disease mainly affecting the elderly. Recent reports have shown an association with pre-existing neurodegenerative diseases. Triggers including diseases, medications and vaccination have been reported although in most patients no clear trigger is identified. MAIN OBSERVATIONS: We report a case of atypical bullous pemphigoid which was strongly suspected to have been triggered by the swine flu vaccination. This is the first reported case of pemphigoid triggered by this vaccine. CONCLUSIONS: The use of the swine flu vaccine is likely to increase in the future and it is important that clinicians are aware of the potential adverse effect of swine flu vaccination induced bullous pemphigoid.
J Dermatol Case Rep
· 2011 Dec · PMID 22408706
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BACKGROUND: The specific dermatoses of pregnancy represent a heterogenous group of ill-defined pruritic skin diseases, unique to pregnancy and post partum period. OBJECTIVE: The aim of our study was epidemiological and c...BACKGROUND: The specific dermatoses of pregnancy represent a heterogenous group of ill-defined pruritic skin diseases, unique to pregnancy and post partum period. OBJECTIVE: The aim of our study was epidemiological and clinical evaluation of various specific dermatoses of pregnancy. METHODS: All patients visiting our antenatal clinic were screened for various pruritic skin conditions and those with specific pregnancy dermatoses were identified and evaluated. RESULTS: Out of 1430 patients screened, nearly 5% (70 cases) patients had specific dermatoses of pregnancy. Intra hepatic cholestasis was the commonest specific pregnancy dermatoses. CONCLUSION: Specific dermatoses of pregnancy can be diagnosed primarily on the basis of clinical features. All of these, except intra hepatic cholestasis, do not have any effect on normal course of pregnancy.
Gönül M, Gül U, Kaya I
… +4 more, Koçak O, Cakmak SK, Kılıç A, Kılıç S
J Dermatol Case Rep
· 2011 Dec · PMID 22408705
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BACKGROUND: Epidemiologic researches about oral mucosal lesions have been performed in different populations. But, in dermatology outpatients, oral mucosal lesions have not been investigated previously. OBJECTIVE: We aim...BACKGROUND: Epidemiologic researches about oral mucosal lesions have been performed in different populations. But, in dermatology outpatients, oral mucosal lesions have not been investigated previously. OBJECTIVE: We aimed to determine the prevalence of oral mucosal lesions among dermatology outpatients and the relationship between OML and smoking, alcohol intake, denture and dental filling use and skin diseases. METHODS: Randomly selected 1041 dermatology outpatients were examined for dermatological diseases and oral mucosal lesions. All of the patients were questioned about smoking, alcohol intake, denture and dental filling use. RESULTS: In 235 patients, oral mucosal lesions were recorded. 268 (25.7%) of the patients had history of smoking, 42 (4%) drinking alcohol and 180 (17.3%) denture and dental filling. 32 (64%) of the smokers, 54 (30%) of denture users and 10 (23.8%) alcohol consumers had at least one OML. Age and smoking were found as significant risk factors for oral mucosal lesions. Fissured tongue was the most common oral lesion and it was seen significantly higher in patients with denture. Smoking was risk factor for coated tongue and linea alba. CONCLUSIONS: Oral mucosa should be examined carefully even if the patients do not attend with the complaint of oral lesions, especially in elderly patients, smokers and denture users.
J Dermatol Case Rep
· 2011 Dec · PMID 22408704
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BACKGROUND: The entity vesicobullous disorders in neonates encompasses a varied spectrum of disorders varying from self limiting to potentially life threatening infectious diseases. OBJECTIVE: To analyse the incidence of...BACKGROUND: The entity vesicobullous disorders in neonates encompasses a varied spectrum of disorders varying from self limiting to potentially life threatening infectious diseases. OBJECTIVE: To analyse the incidence of dermatoses in neonates, stress the importance of simple noninvasive diagnostic procedures with perspective to actual need of active intervention. PATIENTS AND METHODS: Forty four neonates with vesicobullous lesions in departments of dermatology and pediatrics were evaluated with respect to diagnosis, required treatments and follow ups. RESULTS: Out of total 44 neonates, 29 were males and 15 females. Iinfectious dermatoses accounted for: 9% - staphylococcal pyoderma, 4,5% - Group A Streptococcal impetigo, 4,5% - neonatal tinea faciei, 2,3% - neonatal candidiasis, 2,3% - neonatal varicella/chickenpox and 2,3% - scabies. Transient skin lesions were: 41% - erythema toxicum neonatorum, 9% - milia crystallina, 6.8% - neonatal acne, 4,5% - sucking blisters, 2,3% - transient neonatal pustular melanosis, 2,3% - epidermolysis bullosa simplex, 2,3% - incontinentia pigmentii, 2,3% - eosinophilic pustular folliculitis, 2,3% - pemphigus vulgaris and 2,3% - neonatal herpes simplex. CONCLUSIONS: Care has to be instituted to identify accurately infectious diseases and distinguish them from benign transient neonatal dermatoses. Some disorders first manifesting during the neonatal period may also represent harbingers of potential problems during adulthood. Finally, it is relevant to judge whether the treatment is required or not.
J Dermatol Case Rep
· 2011 Sep · PMID 22187582
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Folliculitis has many etiologies including bacterial, fungal, viral and parasitic. Therefore, an accurate determination of the cause is necessary to direct treatment. This is a case of a 60-year-old man who presented wit...Folliculitis has many etiologies including bacterial, fungal, viral and parasitic. Therefore, an accurate determination of the cause is necessary to direct treatment. This is a case of a 60-year-old man who presented with an erythematous papule on his chest. Biopsy showed granulomatous inflammation, abscess formation, and the causative agent was Demodex.
Attia A, Seleit I, El Badawy N
… +2 more, Bakry O, Yassien H
J Dermatol Case Rep
· 2011 Sep · PMID 22187581
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Generalized eruptive histiocytoma is a rare form of non Langerhan's cell histiocytosis. The disease occurs mainly in adults and its etiology is still unknown. We describe a case of 48-year-old female with multiple, firm,...Generalized eruptive histiocytoma is a rare form of non Langerhan's cell histiocytosis. The disease occurs mainly in adults and its etiology is still unknown. We describe a case of 48-year-old female with multiple, firm, hemispherical, redish brown papules. Lesions were distributed on the face, upper limbs and trunk. Patient's general examination and routine laboratory investigations were normal. Excisional biopsy was taken from one representative lesion. Histopathological examination revealed diffuse dermal histiocytic infiltration that was suggestive of generalized eruptive histiocytoma. Confirmatory immunohistochemical staining for CD68 antibody was done and revealed positive results. Based on clinical and histopathological criteria the diagnosis of generalized eruptive histiocytoma was established.In conclusion, we present a rare case of generalized eruptive histiocytoma which is an uncommon form of non Langerhan's cell histiocytosis. The disease does not require treatment since it is a self-healing disease.
J Dermatol Case Rep
· 2011 Sep · PMID 22187580
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BACKGROUND: Progressive symmetrical erythrokeratoderma is characterized by well-demarcated, symmetrically distributed, erythtematous and hyperkeratotic plaques. Treatment options are topical retinoids, emollients, kerato...BACKGROUND: Progressive symmetrical erythrokeratoderma is characterized by well-demarcated, symmetrically distributed, erythtematous and hyperkeratotic plaques. Treatment options are topical retinoids, emollients, keratolytics and topical corticosteroids with limited or no success. Oral retinoids have been shown to be successful in some cases, but recurrence is to be expected on cessation of therapy. Topical calcipotriol is an established mode of treatment for psoriasis and also reported to be effective in many hyperkeratotic skin diseases. MAIN OBSERVATIONS: A 20-year-old female patient presented with reddish-brown lesions in her axillae, groins, submammary regions and on the eyelids. Clinical and histological findings were consistent with the diagnosis of progressive symmetrical erythrokeratoderma. She had noted that her lesions did not improve with topically applied steroids and emollients. We recommended our patient to use topical calcipotriol and observed a remarkable improvement within two weeks. CONCLUSION: When compared with the other treatment modalities, topical calcipotriol is a safe and effective drug with minimal side effects and it would be a good alternative.
Tukenmez Demirci G, Altunay IK, Mertoglu E
… +2 more, Kucukunal A, Sakız D
J Dermatol Case Rep
· 2011 Sep · PMID 22187579
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BACKGROUND: Linear atrophoderma is a rare disease, first described by Moulin in 1992 in 5 patients. It is an acquired unilateral hyperpigmented, depressed band-like areas following the lines of Blaschko. It affects child...BACKGROUND: Linear atrophoderma is a rare disease, first described by Moulin in 1992 in 5 patients. It is an acquired unilateral hyperpigmented, depressed band-like areas following the lines of Blaschko. It affects children or adolescents of both genders involving the trunk or the limbs. It is considered to be a rare cutaneous form of mosaicism. MAIN OBSERVATION: A 39-year-old woman with a 22 years history of unilateral slightly depressed hyperpigmented lesion on her neck was admitted to us. The skin texture was normal and there were no signs of induration or sclerosis. The histopathological examination revealed a normal epidermis outlined by a hyperpigmented basal layer. In the papillary dermis proliferation of superficial vessels with mild lymphocytic infiltrate and melanin-laden macrophages were present. The collagen fibres and elastic fibres were normal. The clinical and histopathological features confirmed the diagnosis of linear atrophoderma of moulin. We discussed the case according to the other cases reported in the literature. CONCLUSIONS: Approximately 28 cases of linear atrophoderma have been reported in literature. The present case has the charecteristic clinical and histopathological features of linear atrophoderma as defined by Moulin, but the localization of the lesion is unusual.
Feldmeyer L, Kerl K, Kamarashev J
… +2 more, de Viragh P, French LE
J Dermatol Case Rep
· 2011 Sep · PMID 22187578
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BACKGROUND: Extramammary Paget's disease is a cutaneous neoplasm that presents as erythematous crusted patches and plaques reminiscent of contact dermatitis or inverse psoriasis that can be a challenge to treat in a tiss...BACKGROUND: Extramammary Paget's disease is a cutaneous neoplasm that presents as erythematous crusted patches and plaques reminiscent of contact dermatitis or inverse psoriasis that can be a challenge to treat in a tissue-sparing manner. The most commonly involved site for this rare disorder is the anogenital region. Surgery is considered as the gold standard therapy. In the last years, the topical use of imiquimod cream in the treatment of this condition has been reported. MAIN OBSERVATIONS: We present a case of a 59-year-old woman with primary extramammary Paget's disease of the vulva, in which a conservative approach to therapy was desired, and who underwent complete and stable remission with imiquimod cream. We also review the previous reports of patients with extramammary Paget's disease treated with imiquimod cream. CONCLUSIONS: Imiquimod therapy may be an alternative for primary as well as recurring extramammary Paget's disease. Treatment-associated morbidity is minimal compared with other therapies, such as surgery which may be debilitating.
J Dermatol Case Rep
· 2011 Sep · PMID 22187577
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BACKGROUND: Red scrotum syndrome is a rare and chronic disease affecting males in their second half of life. It is characterized by erythema with sharpborders, no scaling but burning and pain sensations. MAIN OBSERVATION...BACKGROUND: Red scrotum syndrome is a rare and chronic disease affecting males in their second half of life. It is characterized by erythema with sharpborders, no scaling but burning and pain sensations. MAIN OBSERVATIONS: We report about two cases treated successfully with either doxycycline and tacrolimus or gabapentine. CONCLUSION: For practical purposes we suggest to start treating red scrotum syndrome with doxycycline for 2 weeks and use gabapentin as second-line treatment when doxycycline fails.
J Dermatol Case Rep
· 2011 Jun · PMID 21894255
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Trichomycosis axillaris is a common tropical disease usually affecting the hair shafts of the axillae, characterized by nodular concretions along the hair shafts caused by Corynebacterium tenuis. We describe a 38-year-ol...Trichomycosis axillaris is a common tropical disease usually affecting the hair shafts of the axillae, characterized by nodular concretions along the hair shafts caused by Corynebacterium tenuis. We describe a 38-year-old patient with trichomycosis axillaris. Treatment, which included shaving of affected hair, followed by topical 3% erythromycin cream and clotrimazole powder was fully effective.
J Dermatol Case Rep
· 2011 Jun · PMID 21894254
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A 65-year-old woman presented with widespread necrotising cutaneous ulceration and oral involvement. Past history included rheumatoid arthritis, and a left nephrectomy.Examination revealed multiple violaceous undermined...A 65-year-old woman presented with widespread necrotising cutaneous ulceration and oral involvement. Past history included rheumatoid arthritis, and a left nephrectomy.Examination revealed multiple violaceous undermined ulcers. Blood investigations showed an acute inflammatory response. Skin histopathology showed epidermal ulceration with acute and chronic inflammation. Direct immunofluorescence was negative. A diagnosis of pyoderma gangrenosum with oral involvement was made. Mycophenolate mofetil therapy resulted in complete resolution of her pyoderma gangrenosum. Her treatment was complicated by a left proteus mirabilis psoas abscess. This resolved following four weeks of antibiotics.Pyoderma gangrenosum with oral involvement is rare but has been linked with inflammatory bowel disease and hematological disorders. Oral pyoderma gangrenosum has not previously been described in rheumatoid arthritis. Primary psoas abscess is rare but can develop in immunocompromised patients. Proteus mirabilis has been reported in patients years after nephrectomy. This is a rare case of pyoderma gangrenosum with oral involvement.
Adams D, Athalye L, Schwimer C
… +1 more, Bender B
J Dermatol Case Rep
· 2011 Jun · PMID 21894253
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BACKGROUND: Epidermal nevus syndrome is a multi-system disease with a wide spectrum of clinical presentation. Numerous specialists may be required to address its extra cutaneous manifestations. MAIN OBSERVATIONS: We repo...BACKGROUND: Epidermal nevus syndrome is a multi-system disease with a wide spectrum of clinical presentation. Numerous specialists may be required to address its extra cutaneous manifestations. MAIN OBSERVATIONS: We report a severe case of epidermal nevus syndrome involving the oral cavity, pharynx, and central nervous system in addition to disfiguring skin lesions. CONCLUSIONS: Dermatologists are in a unique position to first render the diagnosis of epidermal nevus syndrome for young patients and ensure appropriate follow-up.
J Dermatol Case Rep
· 2011 Jun · PMID 21894252
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BACKGROUND: Surgical correction of bilateral cicatricial upper and lower eyelid ectropion in an ichthyosis patient remains a challenge in clinical practice. MAIN OBSERVATIONS: A 24-year-old female patient presented to ou...BACKGROUND: Surgical correction of bilateral cicatricial upper and lower eyelid ectropion in an ichthyosis patient remains a challenge in clinical practice. MAIN OBSERVATIONS: A 24-year-old female patient presented to our clinic with bilateral upper and lower eyelid ectropion. Her skin over her entire body and face was dry and scaly. The diagnosis was cicatricial ectropion related in a patient with ichthyosis. The upper eyelids were treated by retroauricular full thickness skin grafts and upper eyelid lateral tarsal strip procedure. And lower eyelids were treated by cheek transposition grafts and lower eyelid lateral tarsal strip procedure. The upper and lower eyelids were corrected successfully with these surgical procedures. CONCLUSIONS: In patients with ichthyosis skin alterations in the eyelid cause shortening of the anterior lamella, subsequently resulting with ectropion. Successful surgical correction with skin grafts or transposition flaps can be performed to lenghten anterior lamella. Adding lateral tarsal strip procedure to skin grafting helps to maintain a beter lid margin apposition.