Biodemography And Social Biology[JOURNAL]
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200 papers
The life-course association of birth-weight genes with self-rated health.
Tong G, Guo G
Biodemography Soc Biol · 2020 · PMID 32727274 · Full text
This study examines the impact of genes associated with normal-range birth weight (2500-4500 grams) on self-rated health in mid-to-late life course. Fifty-eight previously identified genetic variants that explain the var...
This study examines the impact of genes associated with normal-range birth weight (2500-4500 grams) on self-rated health in mid-to-late life course. Fifty-eight previously identified genetic variants that explain the variation in the normal-range birth weight were used to construct a genetic measure of birth weight for the non-Hispanic white sample from the Health and Retirement Study. Our results show that the genetic tendency toward higher birth weight predicts better self-rated health in mid-to-late life course net of various demographic, socioeconomic, and health behavioral factors. We also examine the heterogeneous effects of birth-weight genes across birth cohorts and age groups. Moreover, to clarify the paradox that higher birth weight can predict both better self-rated health and higher BMI, we show the positive association between birth weight genes and BMI can only hold within the normal-range BMI (18 ≤ BMI < 30). Overall, these findings suggest the genetic factors underlying the normal-range birth weight can have life-courseimpacts on health.
The pandemic of 1918 and the heart disease epidemic in middle-aged men and women in the United States.
Blanchard S, Bradshaw BS, Herbold JR … +1 more , Smith DW
Biodemography Soc Biol · 2020 · PMID 32432939 · Publisher ↗
Members of birth cohorts who were alive in 1918 and survived the influenza pandemic were likely to have been "primed" for heart disease in later life. We examine the hypothesis that the twentieth-century heart disease ep...
Members of birth cohorts who were alive in 1918 and survived the influenza pandemic were likely to have been "primed" for heart disease in later life. We examine the hypothesis that the twentieth-century heart disease epidemic was a cohort effect reflecting the changing susceptibility composition of the population.We estimated heart disease death rates by single years of age for cohorts born in 1860-1949. We prepared age-specific rates for calendar years 1900-2016, as well as age-standardized cohort and calendar year rates.Males born in 1880-1919 contributed 90 per cent to 100 per cent of all heart disease deaths among males aged 40-64 from 1940 to 1959, when the heart disease epidemic was at its peak. There was no heart disease epidemic among females aged 40-64. Death from heart disease in females tends to occur at older ages.Cigarette smoking, unemployment, and other factors may have played a role in the heart disease epidemic in men and would have interacted with injury from influenza, but our results suggest that having been alive at the time of the 1918 influenza pandemic probably played an important role.
Role of proximate determinants in recent and past fertility stalls in Bangladesh.
Rahman MM
Biodemography Soc Biol · 2020 · PMID 32432938 · Publisher ↗
The two fertility stalls that occurred in Bangladesh emerged as substantial barriers in controlling its burgeoning vast population. The first stall occurred during 1996-2000 in the mid-transition of fertility, while the...
The two fertility stalls that occurred in Bangladesh emerged as substantial barriers in controlling its burgeoning vast population. The first stall occurred during 1996-2000 in the mid-transition of fertility, while the second stall occurred during the recent period 2011-2014 in the late transition of fertility. This article explores the role of proximate determinants in those stalls by using the data of Bangladesh Demographic and Health Surveys. Data have been analyzed using proximate determinants model and a descriptive analysis technique. Findings show that contraceptive use and induced abortion are the main drivers of fertility transition in Bangladesh. Both stalls in Bangladesh are found to be associated with a stall in induced abortion. In addition, declining postpartum infecundability plays a vital role in setting first stall. At the end of this stall, composition of contraceptive use is also found less efficient. While, declining fertility-inhibiting effect of marriage and a marginal increase in contraceptive use are the additional factors that play key roles in setting second stall. The mixture of contraceptive use shows a shift to a more efficient composition in the recent years. Change in the timing of birth does not show any consistent link with any of the fertility stalls.
Marriage dynamics in old Lower California: ecological constraints and reproductive value in an arid peninsular frontier.
Macfarlan SJ, Schacht R, Foley C … +6 more , Cahoon S, Osusky G, Vernon KB, Tayler E, Henrickson C, Schniter E
Biodemography Soc Biol · 2020 · PMID 32432937 · Publisher ↗
It is commonly expected that natural selection will favor earlier reproduction, yet ecological constraints can force people to delay marriage. Furthermore, humans demonstrate sex-specific preferences in marriage partners...
It is commonly expected that natural selection will favor earlier reproduction, yet ecological constraints can force people to delay marriage. Furthermore, humans demonstrate sex-specific preferences in marriage partners - with grooms normally a few years older than their brides; however, the age at which individuals marry can influence the spousal age gap. We investigate factors influencing age at first marriage and age difference at marriage using nineteenth-century historical demographic data from Baja California Sur, Mexico. Analyses suggest ecological constraints affected male, but not female, age at first marriage. Males who migrated from their natal community and who married in communities whose primary economic activity was agriculture experienced delayed age at first marriage. The age at which females first married increased over time causing a reduction in the age gap between spouses. Furthermore, the spousal age gap showed sex-specific effects: women who married early in life were much younger than their husbands, while women who married late in life were older than their husbands, suggesting that variation in female reproductive value influenced mate choice. Males, on the other hand, who married late in life showed a preference for marrying much younger females, indicating preferences for females with high reproductive value.
Income dividends and subjective survival in a Cherokee Indian cohort: a quasi-experiment.
Singh P, Brown R, Copeland WE … +2 more , Costello EJ, Bruckner TA
Biodemography Soc Biol · 2020 · PMID 32432936 · Full text
Persons with high temporal discounting tend to value immediate gratification over future gains. Low self-reported lifespan (SRL)-an individual's assessment of a relatively short future lifespan-concentrates in low-income...
Persons with high temporal discounting tend to value immediate gratification over future gains. Low self-reported lifespan (SRL)-an individual's assessment of a relatively short future lifespan-concentrates in low-income populations and may reflect high temporal discounting. We use casino-based cash dividends among the Eastern Band of Cherokee Indians (EBCI) as a quasi-experiment to test whether large income gains among EBCI members translate into increased SRL. We used SRL data for EBCI and White youth, aged 19 to 28, participating in two waves of the Life Time Trajectory of Youth (LTI-Y) survey from 2000 to 2010. We controlled for unobserved confounding across individuals, time, and region through a longitudinal design using a difference-in-difference analytic approach (N = 294). We conducted all analyses separately by gender and by quartile of socioeconomic status. Cash dividends correspond with a 15.23 year increase in SRL among EBCI men below the lowest socio-economic quartile at baseline relative to Whites (standard error = 5.39, < .01). Results using other socio-economic cut-points support improved SRL among EBCI men (but not women). The large magnitude of this result among EBCI men indicates that a non-trivial cash dividend to a low-income population may confer long-term benefits on perceptions of future lifespan and, in turn, reduce temporal discounting. EBCI: Eastern Band of Cherokee Indians; SES: Socioeconomic Status; LTI-Y: Life Trajectory Interview for Youth; GSMS: Great Smoky Mountains Study; SRL: Self-Reported Lifespan; SSS: Subjective Social Status.
Weight and economic development: current net nutrition in the late 19th- and early 20th-century United States.
Carson SA
Biodemography Soc Biol · 2020 · PMID 32432935 · Publisher ↗
When traditional measures for material and economic welfare are scarce or unreliable, height and the body mass index (BMI) are now widely accepted measures that represent cumulative and current net nutrition in developme...
When traditional measures for material and economic welfare are scarce or unreliable, height and the body mass index (BMI) are now widely accepted measures that represent cumulative and current net nutrition in development studies. However, as the ratio of weight to height, BMI does not fully isolate the effects of current net nutrition. After controlling for height as a measure for current net nutrition, this study uses the weight of a sample of international men in US prisons. Throughout the late 19th- and early-20th centuries, individuals with darker complexions had greater weights than individuals with fairer complexions. Mexican and Asian populations in the US had lower weights and reached shorter statures. Black and white weights stagnated throughout the late 19th- and early-20th centuries. Agricultural workers' had greater weights than workers in other occupations.
Assessing heterogeneity in menstrual cycles by means of a multilevel latent class approach.
Bassi F, Scarpa B
Biodemography Soc Biol · 2020 · PMID 32065541 · Publisher ↗
In this paper, we study the problem of heterogeneity in cervical mucus hydration at different times relative to the mucus peak both between cycles and women, specifying and estimating appropriate multilevel latent class...
In this paper, we study the problem of heterogeneity in cervical mucus hydration at different times relative to the mucus peak both between cycles and women, specifying and estimating appropriate multilevel latent class models for longitudinal data. We estimate multilevel and growth latent class models which classify women on the basis of the evolution of cervical mucus characteristics observed over the fertile period of each menstrual cycle taking into account that we observe a different number of cycles per woman and correlation over time between consecutive observations. The effect of potential covariates on mucus evolution patterns is as well evaluated. Results confirm the existence of heterogeneity in mucus evolution between cycles and women. Moreover, an important significant effect of a woman's age is found.
Perceived neighborhood social cohesion and cardiometabolic risk: a gene × environment study.
Robinette JW, Boardman JD, Crimmins E
Biodemography Soc Biol · 2020 · PMID 32065540 · Publisher ↗
People living in socially cohesive neighborhoods generally have better health. We extend this research by evaluating the hypothesis that perceived neighborhood cohesion may influence health by attenuating genetic liabili...
People living in socially cohesive neighborhoods generally have better health. We extend this research by evaluating the hypothesis that perceived neighborhood cohesion may influence health by attenuating genetic liability for cardiometabolic risk factors. Using data from the Health and Retirement Study ( = 6615; mean age 69.7), we conducted a gene × environment interaction study hypothesizing that perceived neighborhood cohesion would attenuate the link between polygenic scores for waist-to-hip ratio (WHR) and body mass index and a measure of multisystem cardiometabolic risk (systolic and diastolic blood pressure, heart rate, A1c, C-reactive protein, and total and high-density lipoprotein cholesterol). In support of the hypothesis, results indicated that among people perceiving low neighborhood cohesion, higher WHR polygenic scores were associated with greater cardiometabolic risk. In contrast, the genetic-cardiometabolic risk link was much attenuated among those living in neighborhoods perceived as socially cohesive. Our results support community-level interventions to enhance the social cohesiveness of individuals' neighborhoods which may provide health benefits by reducing the risks associated with known genetic risk factors.
C-reactive protein response to influenza vaccination predicts cardiovascular disease risk in the Philippines.
McDade TW, Borja JB, Lee N … +4 more , Aquino CT, Barrett T, Adair LS, Kuzawa CW
Biodemography Soc Biol · 2020 · PMID 32065539 · Full text
Inflammation is associated with increased risk for chronic degenerative diseases, as well as age-related functional declines across many systems and tissues. Current understandings of inflammation, aging, and human healt...
Inflammation is associated with increased risk for chronic degenerative diseases, as well as age-related functional declines across many systems and tissues. Current understandings of inflammation, aging, and human health are based on studies conducted almost exclusively in high-income nations that rely primarily on baseline measures of chronic inflammation. This analysis investigates the inflammatory response to vaccination as a predictor of cardiovascular disease (CVD) among older women in the Philippines, a lower-middle income nation with rising rates of overweight/obesity and relatively high burdens of infectious disease. Concentrations of C-reactive protein (CRP) were measured at baseline and 72 h following influenza vaccination in 530 women (mean age = 55.2 years). Ankle-brachial index (ABI) - an indicator of peripheral arterial disease and broader CVD risk - was measured approximately three years later. The magnitude of CRP response to vaccination was positively associated with ABI, indicating that a larger inflammatory response predicts lower CVD risk. Baseline CRP was negatively associated with CRP response to vaccination, and was not associated with ABI independently of CRP response. These results suggest that research across ecological settings, and with more dynamic measures of inflammatory response and regulation, may yield important insights into the associations among inflammation, aging, and disease.
The effect of social assistance on kin relationships: evidence from Roma communities.
Čvorović J, Vojinović Ž
Biodemography Soc Biol · 2020 · PMID 32065538 · Publisher ↗
This paper discusses the effects of social assistance on kinship relationships in Roma, a disadvantaged European minority population, and how variation in kin support affects self-reported health and reproductive success...
This paper discusses the effects of social assistance on kinship relationships in Roma, a disadvantaged European minority population, and how variation in kin support affects self-reported health and reproductive success. Data were collected in 2016-7 in several rural Roma settlements in central Serbia. The sample consisted of 143 men and 221 women. Demographic information (e.g., age, gender, educational level, marital and reproductive history, level of socioeconomic status and residence pattern), social assistance history, health status, height, and weight were collected, in addition to kinship relationship dynamics. Receiving social assistance was consistently negatively associated with all measures of kin support, more so for Roma males than females while decreased kin support was found to result in poorer self-rated health and decline in reproductive success.
Effects of wife's and husband's income on wife's reproduction: an evolutionary perspective on human mating.
Fieder M, Huber S
Biodemography Soc Biol · 2020 · PMID 32065537 · Publisher ↗
From an evolutionary perspective, for women mate choice may be of crucial importance particularly concerning resources needed for rearing children. In modern societies, however, resources in terms of income are often pro...
From an evolutionary perspective, for women mate choice may be of crucial importance particularly concerning resources needed for rearing children. In modern societies, however, resources in terms of income are often provided by both women and men. Nonetheless, the effects of a wife's and husband's socioeconomic status on the wife's reproduction have not been investigated on a broader level. We therefore aim to investigate the effects of wife's and husband's income on wife's number of children and her probability of remaining childless using census data from nine countries mainly in the developing world for a total of 782,147 women aged 45-54 years who currently live with a husband and their spouses. Overall, both wife's and husband's income are significantly negatively associated with wife's number of children. Only in Israel do we find a positive association between husband's income and wife's offspring number. A wife's probability of remaining childless, however, increases with increasing own, but decreases with increasing husband's income. We conclude that in this sample of nearly all developing countries, effects of husband's socioeconomic status on wife's reproduction are acting through childlessness.
Biomarkers for demographic research: sperm counts and other male infertility biomarkers.
Westerman R
Biodemography Soc Biol · 2020 · PMID 32065536 · Publisher ↗
Some male infertility biomarkers are etiologically linked to idiopathic infertility in men, the direct cause of which often cannot be determined with conventional sperm count parameters. Open questions remain regarding t...
Some male infertility biomarkers are etiologically linked to idiopathic infertility in men, the direct cause of which often cannot be determined with conventional sperm count parameters. Open questions remain regarding the universal and generic infertility definitions that cover and combine the clinical, epidemiological, and demographic perspectives. The main effort in the application of these infertility biomarkers are accounted by more or less strict discrimination criteria. For male infertility, beyond classical sperm count assessments, the DNA fragmentation index (DFI) is an adequate biomarker. DFI strongly correlates with pregnancy rates and even strict discrimination criteria for infertility outcomes. Other common biomarkers are reactive oxygen species (ROS) and antisperm antibodies (ASAs), which can explain some biomedical infertility disorders within major constraints. More frequently applied in demographic research, telomere length component analysis is based on identifying the genetic impact of cellular longevity. Sperm telomere length is becoming established as a potential biomarker in infertility research. The aim of this review is to provide an overview of the current status and limitations to the application of novel biomarkers, including TEX101, for infertility research. The review also discusses potential options for the use of biomarkers in population-based studies.: ASAs: antisperm antibodies; DFI: DNA fragmentation index; DNA: deoxyribonucleic acid; ECM1: extracellular matrix protein 1; FSH: follicle stimulating hormone; HS: hypospermatogenesis: IVF: in vitro fertilization; LDHC: L-lactata dehydrogenase C chain; MA: maturation arrest; microTESE: microdissection testicular sperm extraction; NOA: nonobstructive azoospermia; NP: nonprogressive; OA: obstructive azoospermia; pH: potential Hyrogenii (pH-value); PR: progressive; PTGDS: prostaglandin D synthese; ROS: reactive oxygen species; SA: semen analysis; SCO: sertoli cell only; SCSA: sperm chromatin structure assay (SCSA); TL: telomere length; TESE: testicular sperm extraction; TEX101: a glycoprotein that belongs to Ly6/urokinase type plasminogen activator receptor-like protein (uPAR)(LU) superfamily, to be a germ-cell-specific molecular sperm extraction; TUNEL: terminal deoxnucleotidyl dispersion tranferase dUTP nick-end labeling; WHO: World Health Organization.
Positive correlation between high mate value and slow life history strategy is moderated by trait heritability.
McDowell J, Starratt VG
Biodemography Soc Biol · 2020 · PMID 33682575 · Publisher ↗
Life history theory - which considers the influence of environmental factors that occur over the course of an organism's life in determining patterns of development and behavior - has been used to provide insight into th...
Life history theory - which considers the influence of environmental factors that occur over the course of an organism's life in determining patterns of development and behavior - has been used to provide insight into the cause and interpretation of a wide variety of individual differences traits. Recent research has added individual differences in mate value to this list, such that high mate value has been correlated with a slow life history strategy. The current research replicated and further explored this relationship across two studies. Consistent with previous research, Study 1 demonstrated a moderate correlation between life-history strategy and a general assessment of self-perceived mate value. Study 2 expanded this investigation to include a multifactor assessment of self-perceived mate value and provided evidence that the relationship between mate value and life history strategy may be moderated by mate value trait heritability. Specifically, the relationship between mate value and life history strategy was found to be significantly stronger for those mate value traits with the lowest heritability estimates. Results are interpreted and discussed in terms of facultative calibration of evolved psychological mechanisms and conditional behavioral strategies.
Sociocultural determinants of health and wealth in historic African Americans.
O'Donnell L, Edgar HJH
Biodemography Soc Biol · 2020 · PMID 33682574 · Publisher ↗
In this study, we examine the impacts of individual ancestry and socioeconomic status (SES) on health in historic African Americans through bioarchaeological means. We estimate ancestry from dental morphology and SES fro...
In this study, we examine the impacts of individual ancestry and socioeconomic status (SES) on health in historic African Americans through bioarchaeological means. We estimate ancestry from dental morphology and SES from the costs of coffin hardware. We include 188 adult individuals from Freedman's Cemetery in Dallas, Texas, and 2,301 individuals of African and European descent for comparison. Freedman's Cemetery functioned as the only cemetery available to freed people and their descendants between 1869 and 1907. Linear discriminant analysis (LDA) of dental morphological traits was used to estimate individual ancestry. LDA results were then used in Cox proportional hazards analysis to examine whether ancestry impacted mortality risk or SES. Ancestry was not found to impact SES. However, paralleling results from analysis of census mortality data, individuals with greater African ancestry on average have shorter lifespans and higher mortality hazards than individuals who have more European ancestry. This finding provides evidence for structural violence in this historic African American skeletal sample. The negative effects of social constructs are embodied and can be detected in skeletal samples through use of statistical methods combined with information about the cultural context in which people lived.
What your genes can (and can't) tell you about BMI and diabetes.
Ng CD, Weiss J
Biodemography Soc Biol · 2020 · PMID 33682573 · Full text
Body mass index (BMI) is commonly used as a proxy for adiposity in epidemiological and public health studies. However, BMI may suffer from issues of misreporting and, because it fluctuates over the life course, its assoc...
Body mass index (BMI) is commonly used as a proxy for adiposity in epidemiological and public health studies. However, BMI may suffer from issues of misreporting and, because it fluctuates over the life course, its association with morbidities such as diabetes is difficult to measure. We examined the associations between actual BMI, genetic propensity for high BMI, and diabetes to better understand whether a BMI polygenic score (PGS) explained more variation in diabetes than self-reported BMI. We used a sample of non-Hispanic white adults from the longitudinal Health and Retirement Study (1992-2016). Structural equation models were used to determine how much variation in BMI could be explained by a BMI PGS. Then, we used logistic regression models (n = 12,086) to study prevalent diabetes at baseline and Cox regression models (n = 11,129) to examine incident diabetes with up to 24 years of follow-up. We observed that while both actual BMI and the BMI PGS were significantly associated with diabetes, actual BMI had a stronger association than its genetic counterpart and resulted in better model performance. Moreover, actual BMI explained more variation in baseline and incident diabetes than its genetic counterpart which may suggest that actual BMI captures more than just adiposity as intended.
Race/ethnicity, maternal educational attainment, and infant mortality in the United States.
Fishman SH, Hummer RA, Sierra G … +3 more , Hargrove T, Powers DA, Rogers RG
Biodemography Soc Biol · 2020 · PMID 33682572 · Full text
This study examines patterns of and explanations for racial/ethnic-education disparities in infant mortality in the United States. Using linked birth and death data (2007-2010), we find that while education-specific infa...
This study examines patterns of and explanations for racial/ethnic-education disparities in infant mortality in the United States. Using linked birth and death data (2007-2010), we find that while education-specific infant mortality rates are similar for Mexican Americans and Whites, infants of college-educated African American women experience 3.1 more deaths per 1,000 live births (Rate Ratio = 1.46) than infants of White women with a high school degree or less. The high mortality rates among infants born to African American women of all educational attainment levels are fully accounted for by shorter gestational lengths. Supplementary analyses of data from the National Longitudinal Study of Adolescent to Adult Health show that college-educated African American women exhibit similar socioeconomic, contextual, psychosocial, and health disadvantages as White women with a high school degree or less. Together, these results demonstrate African American-White infant mortality and socioeconomic, health, and contextual disparities within education levels, suggesting the role of life course socioeconomic disadvantage and stress processes in the poorer infant health outcomes of African Americans relative to Whites.
Obesity-mortality link over the life course: the contribution of population compositional changes.
Zheng H, Echave P, Mehta N
Biodemography Soc Biol · 2020 · PMID 33682571 · Full text
A key uncertainty in the obesity-mortality association continues to be how this association changes over the life course. Prior studies tend to rely on cross-sectional design with static weight status taken at the time o...
A key uncertainty in the obesity-mortality association continues to be how this association changes over the life course. Prior studies tend to rely on cross-sectional design with static weight status taken at the time of the survey. This study tracks a cohort of individuals and employs lifelong body mass index information from the Framingham Heart Study original cohort (1948-2010). We focus on respondents who were younger than age 45 at time of their first survey ( = 2,176) and evaluate how the mortality risk associated with obesity changes over three age groups (below 45, 45-59, and 60 and above) and how population compositions may contribute to this pattern. We find the hazard ratio associated with obesity compared to normal weight decreases over three age groups, but this pattern is influenced by different ages of onset of obesity, inconsistency in the reference group (normal weight) over ages, and mortality selection effects. These factors explain away the decreasing effect of obesity (with onset before age 45) on mortality up to age 60; after age 60, the detrimental effect still declines, but to a much less degree. Later onset of obesity, however, is not significantly associated with excess mortality risks after age 60.
Does Salivary Telomere Length Explain Race/Ethnic Differences in Aging?
Brown L, García C, Ailshire J
Biodemography Soc Biol · 2019 · PMID 33335644 · Full text
Telomere length (TL) is a biomarker that can be used to characterize variability in aging and may explain race/ethnic differences in aging. Yet, it remains unclear if TL is related to aging-associated health risks in mul...
Telomere length (TL) is a biomarker that can be used to characterize variability in aging and may explain race/ethnic differences in aging. Yet, it remains unclear if TL is related to aging-associated health risks in multi-ethnic populations or if it explains race/ethnic differences in health. We examine whether salivary TL (STL) explains any of the race/ethnic variability in 15 indicators of high-risk biological, physical and cognitive health among 4,074 white, black, and Latinx older adults ages 54+ in the 2008 Health and Retirement Study. TL was assayed from saliva using quantitative PCR (T/S ratio). Decomposition analyses from logistic regression models show variation in STL does not account for any of the observed race/ethnic differences health. In age-adjusted, race-stratified models, STL was associated with HDL, total cholesterol, and lung function among whites, but was not associated with any markers of health among black or Latinx groups. In this diverse national sample of older adults, STL does not account for race/ethnic differences in late life health, is associated with relatively few indicators of health among whites, and is not associated with indicators of health among black or Latinx groups. STL may not be a useful biomarker for understanding racial/ethnic differences in population aging among older adults.
Social and demographical determinants of quality of life in people who live with HIV/AIDS infection: evidence from a meta-analysis.
Ghiasvand H, Higgs P, Noroozi M … +7 more , Ghaedamini Harouni G, Hemmat M, Ahounbar E, Haroni J, Naghdi S, Nazeri Astaneh A, Armoon B
Biodemography Soc Biol · 2020 · PMID 30882251 · Publisher ↗
The aim of this meta-analysis is to summarize the available evidence on the social and demographic determinants of health-related quality of life (QoL) for HIV-infected populations in order to provide a direction to poli...
The aim of this meta-analysis is to summarize the available evidence on the social and demographic determinants of health-related quality of life (QoL) for HIV-infected populations in order to provide a direction to policy makers, planners, and program developers on how best to use their resources to improve the QoL of HIV-infected people.PubMed, Science Direct, Web of Science, and Cochrane electronic databases were searched (up to February 2017) to identify the relevant studies. A meta-analysis was conducted with procreate polled odds ratios (ORs and β) and the confidence intervals of 95% on determining factors of QoL in social and demographic terms. Random effect model was applied to calculate pooled estimation, due to varied sampling methods of researches.In total, 5607 papers were identified from 4 databases and additional search in reference lists. Of these, 2107 articles were selected for full-text review. We included 19 studies that met the eligibility criteria. The pooled effect size shows a relative positive impact of social support for QoL among HIV/AIDS patients and its lower boundary is about 0.61 and the higher about 1.49. The pooled effect size has a considerable negative impact stigma on people who live with HIV/AIDS (PWLHs') QoL ranges from -0.34 to -0.32. Low socioeconomic status (poverty situation) was found to have a degenerative impact with PWLHs' QoL. Our finding indicates an association between younger 35 and QoL is negative with a relatively wide range, the minimum level of education has a weak association with PWLHs' QoL (ES: 0.14-0.2).There are several sociodemographic determinants of QoL among PWLHs and in this study, we found that stigma, low level of socioeconomic status, and being younger than 35 years old have a negative association with QoL, while the social support showed a positive association and a minimum level of education did not show a rigorous negative or positive association.
Associations between ethnic identity, regional history, and genomic ancestry in New Mexicans of Spanish-speaking descent.
Healy M, Edgar H, Mosley C … +1 more , Hunley K
Biodemography Soc Biol · 2018 · PMID 30570413 · Publisher ↗
This study examines associations between ethnic identity, regional history, and genomic ancestry in New Mexicans of Spanish-speaking descent (NMS). In structured interviews, we asked 507 NMS to select from a list of eigh...
This study examines associations between ethnic identity, regional history, and genomic ancestry in New Mexicans of Spanish-speaking descent (NMS). In structured interviews, we asked 507 NMS to select from a list of eight ethnic identity terms identified in previous research. We estimated genomic ancestry for each individual from 291,917 single nucleotide polymorphisms (SNPs) and compared genomic ancestry, age, and birthplace between groups of individuals who identified using each ethnic identity term. Eighty-eight per cent of NMS who identified as "Hispanic," "Nuevomexicano/a," and "Spanish," on average, were born in New Mexico, as were the vast majority of their parents and grandparents. Thirty-three per cent of NMS who identified as "Mexican" and "Mexican American" were born in Mexico, as were 59 per cent of their parents and 67 per cent of their grandparents. Average Native American and African ancestry proportions in "Hispanic" (0.26, 0.02, respectively), "Spanish" (0.25, 0.01), and "Nuevomexicano/a" (0.24, 0.01) NMS were significantly lower than in "Mexican American" (0.37, 0.04) NMS. Significant age differences between older "Spanish" and younger "Nuevomexicano/a" individuals, combined with widespread use of the term "Hispanic," may reflect ongoing nomenclature changes. Patterns of correspondence between ethnic identity, ethnic nomenclatures, and genomic ancestry reflect historical patterns of migration, colonization, and cultural change.
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