Urology Journal[JOURNAL]
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200 papers
Bladder Health in U.S. Shift Workers: A Cross-Sectional Study (NHANES).
Diao J, Xie L, Wu B … +2 more , Chen L, Jing H
Urol J · 2025 Oct · PMID 39741399 · Publisher ↗
PURPOSE: Working during non-traditional hours is becoming more prevalent in modern societies and presents a significant hurdle to an individual's circadian rhythm. We examined the bladder health of shift workers in the U...
PURPOSE: Working during non-traditional hours is becoming more prevalent in modern societies and presents a significant hurdle to an individual's circadian rhythm. We examined the bladder health of shift workers in the United States by analyzing information obtained from the National Health and Nutrition Examination Survey. MATERIALS AND METHODS: National Health and Nutrition Examination Survey (NHANES) datasets from 2005 to 2010 were utilized. Regression analyses were used to assess the association between shift work and bladder health (stress incontinence, urge incontinence, and nocturia) by adjusting for age, race, education, smoking, and other factors. RESULTS: The percentage of non-Hispanic Black individuals was notably higher among shift workers (25.8% vs. 17.8%). Among shift workers, there was a lower percentage of individuals with a college degree or higher compared to day workers. Shift work was found to be associated with nocturia in men in the unadjusted model (OR=1.2, 95%CI=1.0-1.5, p = 0.038). However, the adjusted results indicate that the connection is not statistically significant (Adjusted Model II: OR=1.2, 95%CI=1.0-1.5, p = 0.105). Similarly, no statistically significant association was observed between shift work and nocturia in women. There was also no significant relationship between shift work and Stress Urinary Incontinence (SUI) in men or women. The results from the fully adjusted model (Adjusted Model II) indicate a significant association between shift work and the prevalence of Urgency Urinary Incontinence (UUI) in women (OR=1.2, 95%CI=1.0-1.5, p = 0.041). CONCLUSION: Results of this cross-sectional study indicated that shift work was associated with a higher risk of UUI in women. Further research is needed to explore this relationship.
Effect of 3D Modeling of S-fusion software on Positive surgical Margins in Patients who Underwent Radical Retropubic Prostatectomy: A Randomized Prospective Study.
Oguz U, Bekçi T, Öğreden E … +6 more , Aslan S, Tok B, Tok DS, Akyol S, Altun E, Demirelli E
Urol J · 2025 Jan · PMID 39741398 · Publisher ↗
PURPOSE: To investigate the effect of using three-dimensional (3D) modeling before the surgery on positive surgical margins (PSM) in patients who underwent radical retropubic prostatectomy (RRP). MATERIALS AND METHODS: A...
PURPOSE: To investigate the effect of using three-dimensional (3D) modeling before the surgery on positive surgical margins (PSM) in patients who underwent radical retropubic prostatectomy (RRP). MATERIALS AND METHODS: A prospective data analysis of 81 patients who underwent RRP between April 2021 and December 2023 was performed. Patients were randomized into 2 groups. In "3D group" (n:41), patients were evaluated by the surgeon and radiologist by using a 3D modeling of the mpMRI images which were done by two experienced radiologists just before the surgery. In "non-3D group" (n:40), the surgeon evaluated the mpMRI scans and reports by himself without a 3D modeling of the mpMRI before the operation. Finally, positive surgical margins of two groups were compared. RESULTS: The mean age of the patients was 66.7 ± 5.2 and 65.3±4.9 years in 3D group and non-3D group, respectively. (p = .65) Preoperative PSA value, prostate volume, preoperative PIRADS 4 and PIRADS 5 scores, postoperative ISUP grades and T stages were statistically similar in both groups. (p > .05) The PSM rate was 24 (29.6%) in the overall patient population. PSM was detected in 6 (14.6%) and 18 (45%) of the patients in 3D group and non-3D group, respectively. (p = .005) Conclusion: Using a 3D modeling of the mpMRI images before the surgery decreased the PSM rates after radical retropubic prostatectomy. The present study also reveals the importance of collaboration between radiologists and urologists in the accurate preoperative evaluation of prostate cancer.
Erectile Dysfunction and Ejaculatory Dysfunction in Covid-19 Recovered Patient: Temporary or Persistent?
Hadibrata E, Sutyarso S, Busman H … +1 more , Sumardi S
Urol J · 2025 Mar · PMID 39741397 · Publisher ↗
PURPOSE: Examine the prevalence of erectile dysfunction and ejaculatory dysfunction among COVID-19 recovered patients and whether this condition improved over time. The retrospective study of 50 male patients who have re...
PURPOSE: Examine the prevalence of erectile dysfunction and ejaculatory dysfunction among COVID-19 recovered patients and whether this condition improved over time. The retrospective study of 50 male patients who have recovered from COVID-19 infection previously hospitalized in dr. H Abdul Moeloek General Hospital between March 2020 - March 2021. MATERIALS AND METHODS: All of these patients were evaluated in terms of erectile and ejaculation function via phone interview. The International Index of Erectile Function 5 (IIEF-5) and Male sexual health questionnaire ejaculatory dysfunction (MHSQ-EJD) were used to assess the erectile function and ejaculatory dysfunction. Statistical analysis was performed to evaluate whether there was a difference between IIEF-5 & MHSQ-EJD scores within 6 months, 6 to 12 months, and >24 months after COVID-19 infection. RESULTS: The prevalence of ED was 70% and EJD was 2 % during 0-6 months after COVID-19 infection. Mean age and BMI were 50.4 ± 8.5 years and 23.6 ± 1.6 kg/m2 respectively. There are 26 patients (52%) had an educational background lower than bachelor's degree and 24 patients (48%) had an educational background of bachelor's degree or higher. It was reported that 4 patients (8%) had Diabetes Mellitus and 12 patients (24%) had Hypertension. Most were active smokers (74%) and 2 patients (4%) had reported as active alcohol drinkers. There was a statistically significant IIEF-5 scores difference between three periods of time (p <0,001). CONCLUSION: The prevalence of Erectile Dysfunction was high in COVID-19 recovered patients. There was a temporary erectile dysfunction and ejaculatory dysfunction among COVID-19 patients.
A Comprehensive Review of the Complete Primary Repair Technique for Bladder-Exstrophy-Epispadias Reconstruction: First Surgical Attempt Should Be the Best One.
Torabinavid P, Kajbafzadeh AM
Urol J · 2025 Jan · PMID 39741396 · Publisher ↗
PURPOSE: To evaluate the effectiveness of the Complete Primary Repair of Exstrophy (CPRE) technique for bladder exstrophy-epispadias complex (BEEC) reconstruction and its comparison with the Modern Staged Repair of Exstr...
PURPOSE: To evaluate the effectiveness of the Complete Primary Repair of Exstrophy (CPRE) technique for bladder exstrophy-epispadias complex (BEEC) reconstruction and its comparison with the Modern Staged Repair of Exstrophy (MSRE) technique. MATERIALS AND METHODS: A comprehensive literature review of CPRE and MSRE was conducted, focusing on factors such as continence rates, postoperative outcomes, and complications. Various studies on pelvic biometry, surgical approaches, and long-term evaluations of renal function and continence were analyzed. RESULTS: CPRE demonstrates promising outcomes, particularly in resource-limited settings, by reducing the number of surgeries and associated risks compared to MSRE. Success rates for continence post-CPRE were higher when performed correctly in the first attempt, with fewer complications such as vesicoureteral reflux and hydronephrosis. Pelvic biometry assessments, including bladder neck placement and levator ani angle, were significant predictors of successful continence outcomes. CONCLUSION: CPRE offers a viable alternative to MSRE, particularly in low-resource environments, with favorable continence and renal outcomes. Proper surgical execution in the first attempt is critical for long-term success, emphasizing the importance of surgeon expertise and postoperative care. Further long-term studies are necessary to solidify CPRE's role as the primary surgical approach for BEEC.
Genetic Etiology Investigation in Treatment-Resistant Nocturnal Enuresis Children: A descriptive study.
Yener S, Eser M
Urol J · 2025 Sep · PMID 39616448 · Publisher ↗
PURPOSE: Our study aimed to evaluate the genetic etiology of treatment-resistant nocturnal enuresis in children who have undergone at least 6 episodes of behavioral therapy, urotherapy, alarm therapy, and medical treatme...
PURPOSE: Our study aimed to evaluate the genetic etiology of treatment-resistant nocturnal enuresis in children who have undergone at least 6 episodes of behavioral therapy, urotherapy, alarm therapy, and medical treatment. MATERIALS AND METHODS: A total of 21 patients were included in the study. Inclusion criteria for the study comprised children aged 5-18 years diagnosed with treatment-resistant enuresis according to the International Children's Continence Society (ICCS) guidelines. The capture-based Sophia Hereditary Disease Panel by Sophia Genetics was used specifically for nocturnal enuresis, consisting of a panel of 19 genes (AGXT, AQP2, AVPR2, BNC2, CLCNKB, DLG3, ELN, FA2H, FAM20A, FOXP1, HPSE2, KCNJ10, MLXIPL, NPHP3, RNF168, SLC12A3, SLC25A13, SLC5A2, SMARCA2). RESULTS: Patients were analyzed for genetic variations in genes associated with nocturnal enuresis, including AGXT, AQP2, AVPR2, BNC2, CLCNKB, DLG3, ELN, FA2H, FAM20A, FOXP1, HPSE2, KCNJ10, MLXIPL, NPHP3, RNF168, SLC12A3, SLC25A13, SLC5A2, and SMARCA2. No pathogenic changes potentially explaining the etiology of the disease were detected in 20 patients. One patient exhibited a variant in the AQP2 gene at hg19:Chr12:50344908 exon 1, c.295G>A locus, classified as a Variant of Uncertain Significance (VUS) according to the American College of Medical Genetic and Genomics (ACMG) 2015 guidelines. The AQP2 gene is associated with autosomal dominant and autosomal recessive inherited nephrogenic diabetes insipidus (type 2) in the OMIM (Online Mendelian Inheritance in Man) database. CONCLUSION: Our study resembles studies indicating that nocturnal enuresis cases do not have a monogenic etiology but occur with multifactorial effects and have a weak correlation between genotype and phenotype.
Psychological and Pain Factors in Microsurgical Testicular Sperm Extraction (Micro-TESE) for Non-Obstructive Azoospermia: A Comparative Study of Successful and Unsuccessful Cases.
Avci AE, Kendirci M, Basar MM
Urol J · 2024 Nov · PMID 39614644 · Publisher ↗
PURPOSE: This study aimed to assess postoperative pain, depression, and anxiety levels in infertile men who underwent microsurgical testicular sperm extraction (micro-TESE) for non-obstructive azoospermia (NOA) and compa...
PURPOSE: This study aimed to assess postoperative pain, depression, and anxiety levels in infertile men who underwent microsurgical testicular sperm extraction (micro-TESE) for non-obstructive azoospermia (NOA) and compare results between patients with successful and unsuccessful sperm retrieval. MATERIAL AND METHODS: A total of 105 NOA patients participated, completing preoperative Beck Depression Inventory (BDI) and Situational and Transient Anxiety Inventory (SAI and TAI) questionnaires. Postoperatively, Visual Analog Scale (VAS) scores were recorded. Patients were categorized into primary and repeated micro- TESE groups, and scale scores, operation duration, and collected tubule count were compared. The relationship between micro-TESE outcomes, VAS scores, and additional analgesia needs was also examined. RESULTS: Successful sperm retrieval was achieved in 55.9% of patients. While BDI, SAI, and TAI scores showed no significant intergroup differences, micro-TESE (-) patients exhibited significantly higher mean VAS scores (p < 0.001). VAS scores positively correlated with BDI score, operation duration, and tubule count, while patient age inversely correlated with micro-TESE results. CONCLUSION: Infertility, azoospermia, and unsuccessful sperm retrieval impact psychogenic status and pain levels in male patients. Additionally, a history of micro-TESE procedures and their outcomes elevate depression levels.
Time to Reach Stone-free Status in Children Undergoing Retrograde Intrarenal Surgery.
Tagcı S, Demirtaş G, Karabulut B … +1 more , Tiryaki HT
Urol J · 2025 Jan · PMID 39614622 · Publisher ↗
PURPOSE: Retrograde intrarenal surgery has become increasingly popular for renal stone disease but has very different stone-free rates in children. There is insufficient data in the literature regarding how long it takes...
PURPOSE: Retrograde intrarenal surgery has become increasingly popular for renal stone disease but has very different stone-free rates in children. There is insufficient data in the literature regarding how long it takes to reach a stone-free status in children after retrograde intrarenal surgery. We aimed to evaluate the time to reach stone-free status and stone-free rates (SFR) in children who underwent retrograde intrarenal surgery. MATERIALS AND METHODS: This retrospective study included children who had undergone retrograde intrarenal surgery. Ultrasonography was performed three months after the procedures for 18 months to evaluate stone clearance. We analyzed the stone-free rate and time to reach stone-free status. RESULTS: One hundred and five patients (mean age 6.66 + 5.27 years) were evaluated. Fifteen patients had staghorn stones, 31 had multiple stones, and 44 had single stones. The median follow-up period was 29 months (9-44 months) Of the 90 patients who underwent RIRS as the first treatment option, 38 (42.2%) achieved stone-free status with a single procedure, while 30 (33.3%) required repeat RIRS and other procedures.The stone-free rate was achieved in 75.5% of the patients in a mean of 12.25+40.19 months, In the group with staghorn stones, stone-free status was achieved in 4-36 months with a mean of 16.85+12.03 months, in patients with multiple stones in 2-41 months with a mean of 12.72+10.03 months, and in patients with single stones in 1-36 months with a mean of 10.23+9.10 months. Although the staghorn group achieved stone-free time for longer than the other two groups, there was no significant relationship between the three groups (P = .131) and achieved stone-free time. CONCLUSION: A stone-free status can be achieved in children 12 months after retrograde intrarenal surgery. Since stone-free status is achieved over a long period, patient follow-ups should be planned accordingly, and there should be no rush to perform additional interventions in asymptomatic cases with residual stones.
Mini-Incision Graft Removal in a Kidney Donor with Duplicated Inferior Vena Cava and Vein Reconstruction Using the Recipient's Great Saphenous Vein.
Sholan R, Sahratov H
Urol J · 2025 Jan · PMID 39601050 · Publisher ↗
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The Association between Systemic Inflammation and the Prostate Cancer: based on the National Health and Nutrition Examination Survey and Mendelian Randomization Analysis.
Guan R, Wan L, Zhuang C
Urol J · 2025 Sep · PMID 39601049 · Publisher ↗
PURPOSE: The purpose of this combination research was to examine the relationship between systemic inflammation and the risk of prostate cancer (PCa) through the National Health and Nutrition Examination Survey (NHANES)...
PURPOSE: The purpose of this combination research was to examine the relationship between systemic inflammation and the risk of prostate cancer (PCa) through the National Health and Nutrition Examination Survey (NHANES) cross-sectional study and two-sample Mendelian randomization (MR) analysis. MATERIALS AND METHODS: We incorporated NHANES data spanning the years 2001 to 2010, with exposure as systemic inflammation, evaluated using systemic immune-inflammation index (SII) and outcome as PCa, and performed multivariate logistic regression and restricted cubic spline (RCS) to test the correlation between SII and PCa. Further, two-sample MR was used to identify causal associations between specific immune cells and PCa. RESULTS: A total of 7706 participants (age≥40 years) were included in the analysis in the cross-sectional study, including 350 PCa cases, 7356 controls. Higher SII levels were associated with increased odds of PCa (P<.05). The odds ratio (OR) for PCa was 1.51 (95% CI 1.09-2.08) for the highest versus lowest quartile of SII levels in the fully adjusted model. Also, the RCS analysis showed a threshold effect, with SII levels above 8.90 associated with increased odds of PCa. In addition, MR results suggested a causal relationship between CD62L- monocyte, CD62L- HLA DR+ monocyte, CD14+ CD16+ monocyte, CD62L- Dendritic Cell, Monocytic Myeloid-Derived Suppressor Cell, CD28- CD8dim T cell, CD39+ resting CD4 regulatory T cell and PCa (P<.05). CONCLUSION: This combination analysis provides evidence for a significant causal relationship between systemic inflammation and PCa risk. These findings highlight systemic inflammation and inflammatory immune responses as potential modifiable risk factors for PCa.
Comparison of Transurethral Resection of the Prostate (TURP) with 0.5-cm Tissue Preservation Proximal to the Verumontanum and Standard TURP in terms of Postoperative Ejaculation Disorders.
Kalyenci B, Yalçınkaya FR
Urol J · 2025 Jan · PMID 39601048 · Publisher ↗
PURPOSE: To compare postoperative ejaculation disorders (EjDs) between transurethral resection of the prostate (TURP) with 0.5-cm tissue preservation proximal to the verumontanum and the standard TURP procedure. MATERIAL...
PURPOSE: To compare postoperative ejaculation disorders (EjDs) between transurethral resection of the prostate (TURP) with 0.5-cm tissue preservation proximal to the verumontanum and the standard TURP procedure. MATERIALS AND METHODS: Between February 2016 and August 2020, 226 patients who underwent TURP for symptomatic benign prostatic hyperplasia were retrospectively screened. The patients were analyzed in two groups: In Group A (n = 106), TURP was performed by preserving 0.5-cm tissue proximal to the verumontanum, while in Group B (n = 120), standard TURP was performed. The postoperative voiding functions and EjD rates were compared. RESULTS: Similar findings were observed in the international prostate symptom score, health-related quality of life score, maximum urine flow rate, and post-void residual volume in both groups. In Group A, ejaculation was preserved in 55 (51.9%) patients, the ejaculation volume was decreased in 13 (12.3%), and EjD developed in 38 (35.8%). In Group B, ejaculation was preserved in 16 (13.8%) patients, the ejaculation volume decreased in 15 (12.5%), and EjD developed in 89 (74.2%). CONCLUSION: The ejaculatory function of patients can be maintained in the TURP procedure through the preservation of 0.5-cm tissue from the proximal verumontanum. The modification of TURP can further reduce the risks and undesirable effects of the procedure. The implementation of novel surgical technique modifications and technological developments can potentially decrease complication rates. This approach will also eliminate the assumption that the development of EjD is inevitable after prostate surgery.
Epididimal Cyst in Children: A Single-Institutional Experience.
Varlikli O, Akay MA, Metin S … +2 more , Cankorur MA, Anik Y
Urol J · 2025 Mar · PMID 39601047 · Publisher ↗
PURPOSE: Simple epididymal cysts (EC) are rare in childhood and are mostly diagnosed at puberty. Although there is no consensus on the treatment, a conservative approach is generally preferred. To evaluate patients diagn...
PURPOSE: Simple epididymal cysts (EC) are rare in childhood and are mostly diagnosed at puberty. Although there is no consensus on the treatment, a conservative approach is generally preferred. To evaluate patients diagnosed with EC at our clinic in terms of presenting symptoms, diagnosis, and treatment methods. MATERIALS AND METHODS: Data of patients treated for epididymal cysts at our institution between March 2012 and March 2023 were retrospectively analyzed in terms of age, symptomatology, diagnostic method, treatment method, and outcomes. In all cases, the diagnosis of EC was based on physical examination with scrotal ultrasonography (US) confirmation. RESULTS: A total of 1829 patients underwent scrotal Doppler US, and EC was detected in 72 patients (10.7%). The median follow-up period of the 43 patients was 21.7 (6-80 months). Of these, 9 were bilateral (12.5%). The mean age of the patients at presentation was 14.8 years. Forty-one patients had scrotal pain, 12 had scrotal swelling, and 19 incidentally had EC. The cysts were between 1.2- 37 mm. Only 3 (4.1%) patients required surgical excision due to persistent pain. CONCLUSION: EC is a benign lesion, and treatment approaches are usually conservative. Surgical excision is recommended for patients with persistent scrotal pain or an acute scrotum.
Assessing the Knowledge of ChatGPT in Answering Questions Regarding Female Urology.
Cakir H, Caglar U, Halis A … +3 more , Sarilar O, Yazili HB, Ozgor F
Urol J · 2024 Nov · PMID 39580624 · Publisher ↗
PURPOSE: With the recent increase in the use of artificial intelligence in the medical field, this study aimed to evaluate the accuracy and adequacy of ChatGPT's responses to questions related to female urology. METHODS:...
PURPOSE: With the recent increase in the use of artificial intelligence in the medical field, this study aimed to evaluate the accuracy and adequacy of ChatGPT's responses to questions related to female urology. METHODS: Intensive internet research was performed to prepare a frequently asked question (FAQs) list. Scientific questions were created in accordance with the European Urology Association (EAU) Non-neurogenic Female Lower Urinary Tract Symptoms Guidelines, EAU Chronic Pelvis Pain Guidelines, and EAU Neuro-Urology Guidelines. All answers by ChatGPT were analysed by two experienced urologists and each answer was scored between 1 and 4 by the physicians. A score of 1 was the highest and showed that the answer was completely true and sufficient. The reproducibility of ChatGPT answers was evaluated by asking each question twice using two different computers. RESULTS: A total of 96 (97.0%) ChatGPT answers about female urology were accurate and sufficient, and categorized as grade 1. Additionally, two (2.0%) answers were scored as grade 2, and one answer (1.0%) was scored as grade 3. None of ChatGPT's responses about female urology were classified as grade 4. In total, 83 questions were prepared according to EAU guidelines recommendations, and ChatGPT gave complete accurate and satisfactory answers for 68 (82.9%) questions. The reproducibility rate was highest for ChatGPT answers for questions related to urinary incontinence, pelvic organ prolapses, and pelvic pain syndromes, and reproducibility rate was 100% for each subgroup. The reproducibility rate for ChatGPT answers was lowest for CPG questions (84.1%). CONCLUSION: For the first time our study revealed that ChatGPT had an excellent accuracy rate in answering questions related to female urology with 97% success rate. In addition, the outcomes of this study showed that ChatGPT accurately and satisfactorily answered 82.9% of questions about female urology based on EAU guidelines.
The Comparative Study on the Application Value of Transperineal Prostate Combined Biopsy and Transrectal Prostate Systematic Biopsy in Diagnosing Prostate Cancer in Patients with Different PSA Zones.
Wang H, Wang H, Gao W … +8 more , Xu P, Wang J, Xu H, Pan D, Ma Y, Zhang R, Zhang P, Pang K
Urol J · 2025 Jan · PMID 39563488 · Publisher ↗
PURPOSE: This study aimed to compare the effects of transperineal prostate combined biopsy (TP-CB) and transrectal prostate systematic biopsy (TR-SB) on the detection rate and safety of prostate cancer in patients with p...
PURPOSE: This study aimed to compare the effects of transperineal prostate combined biopsy (TP-CB) and transrectal prostate systematic biopsy (TR-SB) on the detection rate and safety of prostate cancer in patients with prostate-specific antigen (PSA) gray zone, PSA levels of 10~20 ng/mL, and 20~40 ng/mL, and explore the comparative value of their applications. MATERIALS AND METHODS: We collected 243 samples from patients with PSA ≤ 40 ng/mL who underwent prostate biopsy. All patients were divided into two groups according to different patterns of prostate biopsy. The detection rates of prostate cancer and clinically significant prostate cancer (CsPCa) in patients with PSA levels of 4~10,10~20, and 20~40 ng/mL were compared between two different biopsy methods, surgical conditions, and the incidence of complications. RESULTS: The rate of a positive prostate cancer biopsy was significantly higher in TP-CB than in TR-SB (P < 0.05). Further subgroup analyses revealed no statistical significance in the rate of positive prostate cancer biopsy in patients with PSA levels of 4~10 and 20~40 ng/mL between the two groups (P > 0.05). However, patients with PSA levels of 10~20 ng/mL in the TP-CB group exhibited a higher detection rate (P < 0.05), with CsPCa accounting for a higher proportion. The TP-CB and TR-SB groups did not exhibit a significant difference in surgical conditions or overall complication rates (P > 0.05). However, the TR-SB group exhibited a higher risk of postoperative febrile infection than the TP-CB group (P < 0.05). CONCLUSION: For patients with PSA in the 'sub-gray zone' (10~20 ng/mL), TP-CB has a better diagnostic and application value and is more suitable for clinical promotion.
Sexual Functions in Men with Congenital Bilateral Absence of the Vas Deferens: A Retrospective Cross-sectional Study with Fertile Men.
Akinsal EC, Baydilli N, Tosun H … +2 more , Kızılay E, Sönmez G
Urol J · 2025 Jan · PMID 39563487 · Publisher ↗
PURPOSE: To examine the sexual and psychological conditions of men with Bilateral Congenital Bilateral Absence of the Vas Deferens (CBAVD), a rare condition that contributes to male infertility, and compare it with healt...
PURPOSE: To examine the sexual and psychological conditions of men with Bilateral Congenital Bilateral Absence of the Vas Deferens (CBAVD), a rare condition that contributes to male infertility, and compare it with healthy fertile men. MATERIAL AND METHODS: A total of 52 patients with CBAVD and 66 healthy, fertile men who attended our infertility and andrology clinic were included in the study. Patients with cognitive impairments, language barriers, significant comorbidities, or a history of urogenital surgery were excluded. Reproductive hormone levels and semen volumes were evaluated. In addition, sexual status was investigated with validated questionnaires such as the International Index of Erectile Function, Male Sexual Health Questionnaire, Arabic Index of Premature Ejaculation, Premature Ejaculation Diagnostic Tool, and Premature Ejaculation Profile. RESULTS: In the CBAVD group, median total testosterone, FSH, LH levels, and semen volume were 401 ng/dL, 3.9 mIU/ml, 3.9 mIU/ml, and 0.9 ml, respectively. These parameters were 376 (ng/dL), 4.8 mIU/ml, 5 mIU/ml, and 3 ml in the control group. Semen volume was significantly lower in CBAVD men (p < 0.001). Questionnaires assessing erectile and ejaculatory function have shown that there was no significant difference between the CBAVD and control groups in terms of erectile function, orgasmic function, and sexual relationship satisfaction. However, sexual desire (p = 0.006) and overall satisfaction (p = 0.028) were found to be higher in the CBAVD group. CONCLUSION: The study suggests that CBAVD may not be a direct etiological factor for erectile dysfunction or premature ejaculation.
Prognostic Significance of the Controlling Nutritional Status (CONUT) Score in Patients with Muscle-Invasive Bladder Cancer after Radical Cystectomy.
Yücel C, Dumanli E, Karabacak MC … +5 more , Akbay EK, Yoldas M, Micoogullari U, Ilbey YO, Keskin MZ
Urol J · 2024 Nov · PMID 39563486 · Publisher ↗
PURPOSE: To assess the impact of the The Controlling Nutritional Status (CONUT) score, an indicator of nutritional status, on the survival and prognosis after radical cystectomy. MATERIALS AND METHODS: The medical record...
PURPOSE: To assess the impact of the The Controlling Nutritional Status (CONUT) score, an indicator of nutritional status, on the survival and prognosis after radical cystectomy. MATERIALS AND METHODS: The medical records of patients who underwent consecutive radical cystectomy operations with the diagnosis of muscle-invasive bladder cancer at our clinic were retrospectively examined. The patients were separated into two groups based on the cut-off CONUT score which was derived using the receiver operating characteristic (ROC) curve. The group with a CONUT score ≥ 3 was categorized as high CONUT, whereas the group with a CONUT score < 3 was categorized as low CONUT. The groups were compaired according to oncological outcomes and survival risk factors. RESULTS: Cancer-specific survival (CSS) and overall survival (OS) were statistically significantly lower in the High CONUT group compared to the Low CONUT group (p < 0.001, p = 0.024, respectively). Age (HR: 1.02, 95% CI: 1.006-1.04, p = 0.011) and CONUT score (HR: 3.92, 95% CI: 2.66-5.77, p < 0.001) were revealed to be independent prognostic variables in the multivariate analysis for OS. CONCLUSION: The CONUT score was found to be an independent predictor of survival in patients with muscle-invasive bladder cancer in this study.
Penile and Testicular Incarceration with a Metal Foreign Body: Full Recovery of Erectile Function after 4 Days of Entrapment.
Jeremić D, Dimitrić Ž, Tomić M … +3 more , Kalači I, Govedarica S, Filipović Đ
Urol J · 2025 Oct · PMID 39497561 · Publisher ↗
Penile incarceration with a foreign body is a rare urological emergency necessitating prompt intervention. We present a 59-year-old patient who entrapped his penis and right testicle with a metal thread reducer for sexua...
Penile incarceration with a foreign body is a rare urological emergency necessitating prompt intervention. We present a 59-year-old patient who entrapped his penis and right testicle with a metal thread reducer for sexual arousal four days prior to admission to the Emergency Room. Ultrasound revealed a significantly reduced Color Doppler signal in the right testicle and a completely absent signal in the penile artery. After admission, the metal reducer was removed using a hacksaw under analgosedation. Magnetic resonance imaging showed penile ischemic changes. The patient experienced a reduction in penile swelling, and parts of the skin highly suspected of necrosis recovered fully with preserved sensation. Despite penile ischemia on magnetic resonance imaging, the patient had a full recovery, obtaining normal erections. He was discharged six days after admission, presenting with a normal International Index of Erectile Function score on the follow-up exam.
Minimalist Approach for HoLEP with A Low-Power Holmium Source: A Retrospective Study.
Inan R, Buldu I
Urol J · 2025 Sep · PMID 39497560 · Publisher ↗
PURPOSE: To assess the efficacy and safety of very low-power Holmium Laser Enucleation of the Prostate (HoLEP) on a 30-W holmium laser source. MATERIALS AND METHODS: With the approval of the local ethics committee, we...
PURPOSE: To assess the efficacy and safety of very low-power Holmium Laser Enucleation of the Prostate (HoLEP) on a 30-W holmium laser source. MATERIALS AND METHODS: With the approval of the local ethics committee, we retrospectively analysed 60 patients treated with HoLEP. There were 30 patients in the low-power (LP) group and 30 patients in the very low-power (VLP) group. For the LP group, we used a 60-W holmium laser machine. Throughout the en bloc process, we used laser settings of 2 J and 20 Hz. We used a 30-W low-power holmium source in the VLP group. We used laser settings of 2 J and 10 Hz. All patients were operated on by an experienced surgeon. We evaluated the surgical parameters and practicality of the low-power laser vs. the very low-power laser. RESULTS: All patients underwent successful HoLEP in the very low-power group; it was not necessary to increase the output of the laser in any case. Mean preoperatively estimated prostate volume was 88.1 mL (range, 30-300 mL). Mean enucleation time and enucleation efficiency were 67.9 min (range, 25-150 min) and 0.99 gm/min (range, 0.8-1.8 gm/min), respectively. No patient required blood transfusion postoperatively. No stress urinary incontinence (SUI) was observed in the 3rd month postoperative follow-up. CONCLUSION: The use of a low-power laser source is encouraging for the learning curve of new surgeons who will begin HoLEP surgery; it can facilitate the adoption of HoLEP in developing countries, where the initial capital investment may be a major obstacle.
Efficacy and Complications of Mitrofanoff Continent Urinary Diversion in Adults with Complex Urethral Strictures: A Single-Center Experience.
Abedi AR, Hosseini J, Hojjati SA … +3 more , Alinejad Khorram A, Nikmaram R, Fakhar F
Urol J · 2024 Nov · PMID 39215576 · Publisher ↗
PURPOSE: The management of complicated and irreparable urethral strictures can be challenging, and continent urinary diversion has emerged as a viable option. This study aims to investigate the complications associated w...
PURPOSE: The management of complicated and irreparable urethral strictures can be challenging, and continent urinary diversion has emerged as a viable option. This study aims to investigate the complications associated with continent urinary diversion using the Mitrofanoff principle in patients with complex urethral strictures that cannot be corrected through urethroplasty surgery. MATERIALS AND METHODS: A total of 22 patients were included in this study, who underwent continent urinary diversion surgery using the Mitrofanoff technique. The patients were monitored for post-surgical complications over an average follow-up period of 28.36±14.26 months. Surgical failure was defined as the inability to completely and regularly empty urine from the new urinary tract. RESULTS: Half of the patients experienced surgical complications, with only one case resulting in surgery failure. The most common complication observed was stoma stenosis. Two patients reported slight urinary leakage from the stoma site. Notably, all patients except one, regained control over their urine after the procedure. Early therapeutic interventions were classified according to the Clavien-Dindo grading system, showed that none of the patients experienced severe complications (grade 4 or 5). CONCLUSION: The study examines the outcomes of continent urinary diversion using the Mitrofanoff technique in adults with complex urethral strictures, providing realistic expectations of complications. Overall, the study shows that this approach is a viable option with a high success rate and manageable complication for individuals with complex urethral strictures that cannot be corrected through urethroplasty surgery.
Investigating the Prevalence of Autonomic Neuropathy in Diabetic Patients with Urinary Irritation Symptoms Without a Known Cause.
Ansari Djafari A, Javanmard B, Koohifard A … +4 more , Hojjati F, Alinejad Khorram A, Razzaghi Z, Hojjati SA
Urol J · 2024 Nov · PMID 39215575 · Publisher ↗
PURPOSE: Evaluating pseudomotor performance can be a valuable tool for investigating the peripheral autonomic nervous system in diabetic patients. Sudoscan, a simple and non-invasive method for assessing pseudomotor perf...
PURPOSE: Evaluating pseudomotor performance can be a valuable tool for investigating the peripheral autonomic nervous system in diabetic patients. Sudoscan, a simple and non-invasive method for assessing pseudomotor performance, has been developed in recent years. This study aimed to investigate autonomic neuropathy using Sudoscan in diabetic patients with lower urinary tract symptoms (LUTS) of unknown cause. MATERIALS AND METHODS: In this cross-sectional study conducted from April 2022 to April 2023, we included 195 patients with type 2 diabetes who were referred to the urology clinic. We extracted demographic, clinical, and laboratory data from the patient files and evaluated urinary symptoms using the International Prostate Symptom Score (IPSS) questionnaire. Patients underwent Sudoscan testing to evaluate autonomic neuropathy in the physical medicine and rehabilitation clinic. To further assess urinary irritative symptoms, patients underwent urodynamic studies (UDS) and ultrasonography. RESULTS: The Sudoscan test results showed that autonomic neuropathy was present in 77 patients (40%), with 43 (22.1%) having moderate and 44 (22.6%) having severe neuropathy. Patients with autonomic neuropathy were found to be older, had longer diabetes durations, higher average blood glucose levels, and higher creatinine levels. Additionally, we found a significant correlation between autonomic neuropathy and signs of high post-void residue on ultrasound and detrusor contraction disorders on UDS (p-value < 0.05). CONCLUSION: Our study found a higher prevalence of autonomic neuropathy in diabetic patients with LUTS using Sudoscan (40%). Longer diabetes duration and poor glycemic control were associated with an increased risk of autonomic neuropathy linked with LUTS, such as urge incontinence.
Translation and Validation of the Persian Version of the Wisconsin Stone Quality of Life Questionnaire.
Hoseinbeigi MS, Shakiba B, Faegh A … +2 more , Soleimani S, Maghsoudi R
Urol J · 2024 Nov · PMID 39215574 · Publisher ↗
PURPOSE: Patients with kidney stones have a lower quality of life (QOL) than healthy patients; however, treatment guidelines neglect their QOL. Wisconsin stone QOL test (WIS-QOL) is the first specific questionnaire for u...
PURPOSE: Patients with kidney stones have a lower quality of life (QOL) than healthy patients; however, treatment guidelines neglect their QOL. Wisconsin stone QOL test (WIS-QOL) is the first specific questionnaire for urolithiasis patients. This study evaluated the reliability and validity of the translated Persian version of the WIS-QOL questionnaire in patients with kidney stones. MATERIAL AND METHODS: All patients (> 18 years old) with a history of urolithiasis were included in this cross-sectional. The WIS-QOL questionnaire was translated depending on Hutchinson's guideline. Effects of urolithiasis on the patient's social activity, emotions, disease, and vitality were evaluated. Pearson Correlation and Cronbach's alpha test were used to assess the validity and reliability of the questionnaire. All data were analyzed by SPSS software version 26.0. RESULTS: Among 154 urolithiasis patients, 94 (61%) were males, and 60 (39%) were females. The mean age was 50.4 years (SD: ± 13.6), and the mean QOL score was 84.7 (SD: ± 21.8). For each question, the numerical value of the Pearson Correlation Coefficient has been compared with the numerical value, and the validity of the questionnaire was confirmed. The overall Cronbach's alpha was 0.94 for all four areas of the questionnaire, so the reliability of the questionnaire in Persian was confirmed. CONCLUSION: The present study showed the reliability and validity of the Persian version of the WIS-QOL questionnaire in symptomatic urolithiasis patients. The present study showed the status and impact of urolithiasis on QOL however, longitudinal and prospective studies should be done to specify changes over time.
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