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Cranio[JOURNAL]

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Cross-sectional and retrospective study regarding the changes in the spatial position of the hyoid bone and upper airways before and after orthodontic therapy in developing patients with normocclusion.

Reichard-Monefeldt G, Diéguez-Pérez M

Cranio · 2025 Sep · PMID 38747053 · Publisher ↗

OBJECTIVE: The objective was to study the effect of orthodontic therapy regarding the position of the hyoid bone and upper airways in nighty-one 6-21 year-old Caucasian patients with normoclussion. METHODS: Nineteen vari... OBJECTIVE: The objective was to study the effect of orthodontic therapy regarding the position of the hyoid bone and upper airways in nighty-one 6-21 year-old Caucasian patients with normoclussion. METHODS: Nineteen variables were analyzed by teleradiography. The differences were analyzed with the ANOVA test of repeated measures with an intra-group factor for two occasions. RESULTS: The statistical analysis revealed a greater influence on the variables Hy-MP (12.3 vs 14.2), Hps-C3 (25.2 vs 28.1), Hpi-C3 (28.8 vs 35.5), H°-C3 (14.4 vs 12.7), Hps-Rg (36.0 vs 42.7), Hpi-Rg (34.1 vs 39.7), USP (16.2 vs 20.2), MPP (12.9 vs 14.8), C3P (10.6 vs 12.8), PNS-Ba (43.5 vs 66.5), PtV-Ad (12.0 vs 17.1) and PtM-Ba (33.9 vs 35.9), and Ad2-SO (24.16 vs 20.87). DISCUSSION: Significant differences were observed between most of the airway and hyoid bone variables before and after orthodontic treatment in our Spanish pediatric population, especially in the nasopharynx.

Voice quality in patients with temporomandibular disorders.

Jamshidpour P, Moradi N, Raiesian S … +4 more , Masoudrad M, Seyedtabib M, Soltani M, Shaterzadeh Yazdi MJ

Cranio · 2025 Sep · PMID 38738830 · Publisher ↗

OBJECTIVES: This study assessed the voice quality in TMD patients compared to healthy individuals using the Dysphonia Severity Index (DSI) and evaluated the correlation between the DSI and TMD severity. METHODS: Patients... OBJECTIVES: This study assessed the voice quality in TMD patients compared to healthy individuals using the Dysphonia Severity Index (DSI) and evaluated the correlation between the DSI and TMD severity. METHODS: Patients who had TMD with Fonseca's anamnestic index were subjected to an examination based on the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD). A sample of 35 patients with TMD and 36 healthy subjects were included in the study. RESULTS: There were significant differences in the DSI score and its components between healthy subjects and TMD patients ( < .001). A significant correlation was found between the DSI scores and TMD severity (Spearman's rho: -0.90,  < .001). CONCLUSION: Patients with TMD demonstrated lower DSI scores and lower voice quality compared to healthy subjects.

Effectiveness of conservative approaches on otologic signs and symptoms in patients with temporomandibular disorders and Meniere's disease: A systematic review.

Ferrillo M, Viola P, Astorina A … +4 more , Chiarella G, Fortunato L, de Sire A, Giudice A

Cranio · 2025 Sep · PMID 38711403 · Publisher ↗

OBJECTIVE: This systematic review aimed to evaluate the effectiveness of conservative approaches on otologic signs and symptoms in patients affected by Menière's Disease (MD) and temporomandibular disorders (TMD). METHOD... OBJECTIVE: This systematic review aimed to evaluate the effectiveness of conservative approaches on otologic signs and symptoms in patients affected by Menière's Disease (MD) and temporomandibular disorders (TMD). METHODS: PubMed, Scopus, and Web of Science were systematically searched to identify studies presenting participants with a diagnosis of MD associated with TMD, conservative approaches as interventions, and modification of the otological signs and symptoms as outcome. RESULTS: Out of 627 articles assessed for eligibility, two studies were included. Both studies showed a significant reduction of Situational Vertigo Questionnaire after treatment, number of vertigo spells, Functional Level Scale, Dizziness Hearing Inventory, and Tinnitus Handicap Inventory, after occlusal splint therapy. No significant differences were found in terms of pure-tone audiometry average. CONCLUSION: Findings of this systematic review suggested that conservative approaches might improve vertigo in patients affected by MD and TMD. However, the low number of included studies makes difficult to draw strong conclusions.

The role of ultrasound imaging of temporomandibular joint condyle-disc complex disorders.

Karabulut İ, Diraçoğlu D, Çapan N … +4 more , Ünsal G, Özcan İ, Cicciù M, Minervini G

Cranio · 2025 Mar · PMID 38695317 · Publisher ↗

OBJECTIVE: This study aimed to determine the diagnostic value of ultrasonography (US) in internal derangements of temporomandibular joint (TMJ) and to compare its efficacy with magnetic resonance imaging (MRI). METHODS:... OBJECTIVE: This study aimed to determine the diagnostic value of ultrasonography (US) in internal derangements of temporomandibular joint (TMJ) and to compare its efficacy with magnetic resonance imaging (MRI). METHODS: Fifty patients with MRI indications due to a TMJ disorder were enrolled. Findings of the clinical examination, US examination and MRI examination were noted by seperate clinicians and the sensitivity, specificity and diagnostic accuracies of all examinations were compared. RESULTS: When compared with MRI, the sensitivity, specificity and diagnostic accuracy of the clinical examination for the internal derangements were 73%, 37%, and 70%, respectively and 75.7%, 33.3% and 73.0% for US examination, respectively. CONCLUSION: US can be considered as an alternative to MRI as it can be used to detect the disc position, internal derangements, intraarticular fluid accumulations and superficial condyle changes with minimally better results than clinical examination.

Cross-cultural adaptation and psychometric properties of the Persian version of the Geriatric Sleep Questionnaire (P-GSQ).

Najafi H, Hosseinnataj A, Esmailpour Moalem A … +2 more , Ilali ES, Papi S

Cranio · 2025 Sep · PMID 38661332 · Publisher ↗

OBJECTIVE: This study aimed to validate the Geriatric Sleep Questionnaire (GSQ) for assessing subjective sleep quality among elderly individuals in Iran. METHODS: The GSQ underwent evaluation for face and content validit... OBJECTIVE: This study aimed to validate the Geriatric Sleep Questionnaire (GSQ) for assessing subjective sleep quality among elderly individuals in Iran. METHODS: The GSQ underwent evaluation for face and content validity. Participants were selected via convenience sampling from five healthcare centers. Sociodemographic variables, including gender, number of children, recreational activities, budget deficits, and family conflicts were analyzed. Confirmatory factor analysis was conducted to verify the results. Internal consistency was assessed using Cronbach's α, and test-retest reliability was evaluated using the intraclass correlation coefficient (ICC). RESULTS: 200 older adults (mean age 66.8 years) completed the questionnaires. Face and content validity were confirmed by 30 experts (S-CVI/average = 0.96). The final model exhibited good fit indices (χ2/df = 2.89, CFI = 0.96). The scale demonstrated acceptable internal consistency (α = 0.81) and test-retest reliability (ICC = 0.98). CONCLUSION: The Persian GSQ demonstrates high reliability and validity for assessing sleep quality in older adults, aiding research in this field.

Temporomandibular disorder symptoms and their association with quality of life of dental patients in Malaysia.

Bahar AD, How QY, Tan XP

Cranio · 2024 May · PMID 38573060 · Publisher ↗

OBJECTIVE: To assess the prevalence of temporomandibular disorders (TMD) and their effects on quality of life (QoL) of dental patients. METHODS: A survey consisting of two validated questionnaires was distributed to dent... OBJECTIVE: To assess the prevalence of temporomandibular disorders (TMD) and their effects on quality of life (QoL) of dental patients. METHODS: A survey consisting of two validated questionnaires was distributed to dental patients registered at the University of Malaya Faculty of Dentistry. The Fonseca Anamnestic Index (FAI) evaluates the prevalence and severity of TMD, while the Oral Health Impact Profile - Temporomandibular Disorder (OHIP-TMD) appraises the effects of TMD on oral health-related QoL. RESULTS: Out of 342 patients (aged 16 to 50 years, 45% male and 55% female) enrolled in the survey, 50.9% had varying degrees of TMD. All 7 domains of OHIP-TMD showed a statistically significant correlation with TMD severity. CONCLUSION: TMD seems to be prevalent among Malaysian dental patients. Not only does TMD affect the QoL of an individual, but the more severe the degree of reported symptoms, the poorer their perceived oral health QoL.

Association between oral health-related quality of life and symptoms of temporomandibular disorder among older adults: A cross-sectional study.

de Oliveira LV, de Almeida Dantas PP, de Macêdo Santos JW … +3 more , Colussi PRG, Barros MMAF, Muniz FWMG

Cranio · 2025 Sep · PMID 38572897 · Publisher ↗

OBJECTIVE: Evaluate the association between oral health-related quality of life (OHRQoL) and self-reported symptoms of TMD. METHODS: Representative samples of older adults (≥60 years) were included ( = 569). Both TMD sym... OBJECTIVE: Evaluate the association between oral health-related quality of life (OHRQoL) and self-reported symptoms of TMD. METHODS: Representative samples of older adults (≥60 years) were included ( = 569). Both TMD symptoms and OHRQoL were assessed by Fonseca Anamnestic Index (FAI) and Oral Health Impact Profile-14 (OHIP-14), respectively. Prevalence (those answering "frequently" or "always" in at least one question), severity (total means scores), and extent (number of questions answered as "frequently" or "always") of OHRQoL were estimated. RESULTS: Overall, 33.4% and 9.5% had mild or moderate/severe TMD symptoms. Those with any symptom of TMD had a prevalence ratio (PR) 38% higher for the worst OHRQoL (95% confidence interval [95%CI]:1.04-1.82) compared to those without TMD symptoms. Worst OHRQoL were observed for those with mild (PR:1.35; 95%CI:1.01-1.81) and moderate/severe TMD (PR:1.53; 95%CI:1.04-2.26). Similar results were detected in the severity and extent of OHRQoL. CONCLUSION: Severity TMD was associated with worse ORHQoL.

The painful mind.

Kandasamy S

Cranio · 2024 Jul · PMID 38549259 · Publisher ↗

Abstract loading — click title to view on PubMed.

Patients' perceptions of the importance of improvements and side effects from mandibular advancement device therapy for obstructive sleep apnea and snoring.

Mezzofranco L, Zalunardo F, Savin S … +2 more , Agostini L, Gracco ALT

Cranio · 2025 Sep · PMID 38461515 · Publisher ↗

OBJECTIVE: To assess which improvements and side effects are considered most important by patients with OSA treated with a MAD. METHODS: A specific questionnaire consisting of 20 questions, including 10 questions on impr... OBJECTIVE: To assess which improvements and side effects are considered most important by patients with OSA treated with a MAD. METHODS: A specific questionnaire consisting of 20 questions, including 10 questions on improvements and 10 on side effects, was developed and mailed to all subjects (54). RESULTS: 42 patients, participated in the survey by answering the questionnaire. The results showed that patients placed greater importance on the positive outcomes of treatment, with the most significant being the reduction in snoring and improvement in sleep quality. On the other hand, the side effects of difficulty speaking with the device, tooth mobility, and foreign body sensation were considered important. CONCLUSIONS: The advantages perceived by the patients appear to outweigh the disadvantages, especially the reduction of snoring, increased productivity, and improved social and intellectual life. Most significant side effects are reversible and short-term, while occlusal changes, is not considered important by patients.

Depression and the risk of developing temporomandibular disorders in different diagnostic groups: A systematic review with meta-analysis.

de Almeida Hoff E, Grossi RK, Bozzetti Pigozzi L … +6 more , Bueno CH, Pattussi MP, Rossi T, Quarti Irigaray T, Weber JBB, Grossi ML

Cranio · 2025 Sep · PMID 38461514 · Publisher ↗

OBJECTIVE: To evaluate the role of depression in the development of TMD groups. METHODS: This systematic review with meta-analysis compared the prevalence and scores of depression between TMD groups and controls. RESULTS... OBJECTIVE: To evaluate the role of depression in the development of TMD groups. METHODS: This systematic review with meta-analysis compared the prevalence and scores of depression between TMD groups and controls. RESULTS: The results showed that depression was a significant risk factor in the development of RDC/TMD axis I muscle disorders (group I) and arthralgia/osteoarthritis/osteoarthrosis (group III), and non-significant for disc displacements (group II). Severe depression had almost four times the risk of developing TMD as compared to moderate depression. CONCLUSION: These findings suggest that addressing psychological factors in general, and depression in particular, in the managemenof TMD is crucial, especially in those TMD groups with higher pain levels (I and III), and the TMD pain reduction is crucial in reducing depression levels.

Treatments related to temporomandibular disorders among patients with prevalent types of Ehlers-Danlos syndrome in Sweden.

Yekkalam N, Novo M, Wänman A

Cranio · 2025 Jul · PMID 38415674 · Publisher ↗

The aim of this study was to assess the received TMD treatment modalities and the perceived outcome among the frequent types of EDS. A digital questionnaire was sent to the member of the National Swedish EDS Association... The aim of this study was to assess the received TMD treatment modalities and the perceived outcome among the frequent types of EDS. A digital questionnaire was sent to the member of the National Swedish EDS Association during January-March 2022. The subsamples of hypermobile and classical EDS were constructed. Almost 90% reported TMD symptoms. Bite splint therapy, counselling, jaw training and occlusal adjustment were reported as the most common treatments with no statistically significant difference in terms of good effect between the two subsamples. Hypermobile and classical EDS might consider as an entity with regards to TMD.

Temporomandibular disorder pain in older adolescents-young adults: Interrelationship with somatic burden, mental ill-being, and well-being.

Yap AU, Wee KK, Loh JY … +2 more , Marpaung C, Natu VP

Cranio · 2025 Sep · PMID 38415618 · Publisher ↗

OBJECTIVES: The associations of Temporomandibular disorder (TMD) pain with somatic symptoms, mental ill-being/distress, and well-being were explored, along with the mental correlates of TMD (TS) and somatic symptom (SS)... OBJECTIVES: The associations of Temporomandibular disorder (TMD) pain with somatic symptoms, mental ill-being/distress, and well-being were explored, along with the mental correlates of TMD (TS) and somatic symptom (SS) burden in older adolescents-young adults. METHODS: TMD/somatic symptoms were appraised with the five quintessential symptoms (5Ts) of the DC/TMD/Somatic Symptom Scale-8, whereas mental distress/well-being was assessed with the Depression, Anxiety, Stress Scales-21/Scales of Psychological Well-being-18. Data were examined using Chi-square/non-parametric tests and multivariate analyses (α = .05). RESULTS: Among the 366 participants, 51.4%, 28.1%, 6.8%, and 13.7% had no TMD (NT), TMD pain (TP), TMD dysfunction (TD), and combined TMD (CT) respectively. Though mental distress varied substantially (CT, TP>NT, TD), no significant differences in well-being were discerned. SS burden, but not TS burden, was moderately correlated to distress. CONCLUSIONS: The prospect of TMD pain was increased by being female, depressed, and anxious but reduced by "positive relations with others" and "self-acceptance".

The evolution of a field: A challenge and an opportunity.

Manfredini D

Cranio · 2024 May · PMID 38409867 · Publisher ↗

Abstract loading — click title to view on PubMed.

Age distribution of East Asian TMD patients and age-related differences in DC/TMD axis I findings.

Yap AU, Lei J, Park JW … +4 more , Liu C, Kim SH, Lee BM, Fu KY

Cranio · 2025 Jul · PMID 38369853 · Publisher ↗

OBJECTIVES: The pattern of age distribution in East Asian temporomandibular disorder (TMD) patients and age-related differences in DC/TMD diagnostic subtypes/categories were evaluated. SUBJECTS AND METHODS: TMD patients... OBJECTIVES: The pattern of age distribution in East Asian temporomandibular disorder (TMD) patients and age-related differences in DC/TMD diagnostic subtypes/categories were evaluated. SUBJECTS AND METHODS: TMD patients from two University-based centers in China and South Korea were enrolled. Axis I physical diagnoses were rendered according to DC/TMD. Patients were categorized into six age groups (15-24, 25-34, 35-44, 45-54, 55-64, and 65-84 years; Groups A-F respectively). RESULTS: Youths/young adults (Groups A-C) formed 74.1% of TMD patients. TMJ disc displacements (74.9%), arthralgia (49.2%), and degenerative joint disease [DJD] (36.8%) were the most common TMD subtypes. The majority had combined (54.0%) and chronic (58.5%) TMDs. Youths/young adults and middle-aged/old adults had substantially lower frequencies of merely pain-related (6.2-14.5%) and intra-articular (13.8-16.8%) TMDs correspondingly. "Being female" increased the prospects of pain-related/combined TMDs by 96%/49%, respectively. CONCLUSIONS: East Asian TMD patients comprised mostly of youths/young adults who had an alarmingly high prevalence of TMJ DJD.

Central effects of trigeminal electrical stimulation.

Monaco A, Cattaneo R, Di Nicolantonio S … +3 more , Strada M, Altamura S, Ortu E

Cranio · 2025 Jul · PMID 38032105 · Publisher ↗

This is a review of the literature on the main neuromodulation techniques, focusing on the possibility of introducing sensory threshold ULFTENS into them. Electro neuromodulation techniques have been in use for many year... This is a review of the literature on the main neuromodulation techniques, focusing on the possibility of introducing sensory threshold ULFTENS into them. Electro neuromodulation techniques have been in use for many years as promising methods of therapy for cognitive and emotional disorders. One of the most widely used forms of stimulation for orofacial pain is transcutaneous trigeminal stimulation on three levels: supraorbital area, dorsal surface of the tongue, and anterior skin area of the tragus. The purpose of this review is to trigger interest on using dental ULFTENS as an additional trigeminal neurostimulation and neuromodulation technique in the context of TMD. In particular, we point out the possibility of using ULFTENS at a lower activation level than that required to trigger a muscle contraction that is capable of triggering effects at the level of the autonomic nervous system, with extreme ease of execution and few side effects.

Association between knowledge and attitudes towards pediatric obstructive sleep apnea and dental specialty.

Díaz-Díaz MF, Schlaefli-Arrieta X, Caballero García S … +1 more , Geller Palti D

Cranio · 2025 Jul · PMID 37982430 · Publisher ↗

OBJECTIVE: To associate the knowledge and attitudes about Pediatric Obstructive Sleep Apnea (POSA) with the specialty of dentists in Metropolitan Lima, Peru. METHODS: A cross-sectional, analytical observational study was... OBJECTIVE: To associate the knowledge and attitudes about Pediatric Obstructive Sleep Apnea (POSA) with the specialty of dentists in Metropolitan Lima, Peru. METHODS: A cross-sectional, analytical observational study was carried out during 2021-2022. Two hundred and ten orthodontists and pediatric dentists were surveyed using the adapted and validated Spanish translation of the OSAKA-KIDS questionnaire and additional sociodemographic questions. RESULTS: The data indicated an association between dental specialty and the professional's knowledge about POSA. Orthodontists were 59% less likely to have acceptable knowledge, compared to pediatric dentists ( = .013, IC 95% 0.21-0.83). The study revealed an association between the professional's attitudes and three intervening variables: age ( = .025), clinical experience ( = .049) and sector of practice ( = .020). CONCLUSION: Knowledge was associated with the dental specialty of professionals in the sample included, whilst attitudes were not.

Comparison of symptoms, signs and magnetic resonance imaging in children aged 5-18 years with temporomandibular joint disease.

Demir MG

Cranio · 2025 Sep · PMID 37982425 · Publisher ↗

BACKGROUND: Temporomandibular joint diseases (TMD) are an important clinical condition in childhood as in adults. There is variation in the frequency and distribution of complaints in children about this disorder. MATERI... BACKGROUND: Temporomandibular joint diseases (TMD) are an important clinical condition in childhood as in adults. There is variation in the frequency and distribution of complaints in children about this disorder. MATERIALS AND METHODS: This study was conducted on 407 children aged 5-18 years. Patients with dentofacial function problems, trauma, history of surgery, and malignancy were excluded from the study. Patients with temporomandibular magnetic resonance imaging in their records were classified as normal, reduction disc displacement and non-reduction disc displacement. RESULTS: Patients symptoms were click (77.2%), pain (71.5%), headache (61.2%), bruxism (31.9%), locking (28%), difficulty in mouth opening (24.3%). The most common clinical findings are normal mouth opening (62.2%) and deviation (44.9%). When the MR results were examined, 55.1% of female and 66.6% of male were observed to be normal, and this statistically shows that males have more normal MR findings. CONCLUSION: TMD are also observed in children. Clinical history and findings are helpful in diagnosis, but the contribution of imaging methods may be limited. If head and neck pain is detected in children, TMD should be kept in mind.

The relationship between aerodynamic characteristics of the upper airway and severity of obstructive sleep apnea in adults.

Wang X, Jia L, Xu X … +1 more , Guo J

Cranio · 2025 Jul · PMID 37980603 · Publisher ↗

OBJECTIVE: To investigate the relationship between aerodynamic characteristics of the upper airway and severity of obstructive sleep apnea (OSA) in adults. METHODS: Ninety-seven adult OSA patients underwent polysomnograp... OBJECTIVE: To investigate the relationship between aerodynamic characteristics of the upper airway and severity of obstructive sleep apnea (OSA) in adults. METHODS: Ninety-seven adult OSA patients underwent polysomnography and cone beam computed tomography (CBCT). The anatomical and aerodynamic characteristics were measured based on CBCT images and computational fluid dynamics modelling of the upper airway. RESULTS: After controlling for patients' gender, age, and body mass index (BMI), the maximum velocity during inspiration (In-Vmax) led to the largest increase in the explanatory power of apnea-hypopnea index (AHI) variation. The In-Vmax was closely correlated with the minimum axial area, and their relationship was represented by an inversely proportional fitted curve. CONCLUSIONS: The In-Vmax was the most relevant to OSA severity, and it could be used to assist in recognizing severe OSA patients and as a primary variable to evaluate treatment outcomes of OSA. The In-Vmax was closely related to the most constricted area of the upper airway.

The prevalence of bruxism and oral parafunction activities among Israeli juveniles with autism spectrum disorder: A preliminary study during the COVID-19 pandemic.

Winocur-Arias O, Amitai BC, Winocur E … +3 more , Shmuly T, Grinstein Koren O, Reiter S

Cranio · 2025 Jul · PMID 37964571 · Publisher ↗

OBJECTIVE: To evaluate the prevalence of oral habits, bruxism, and Temporomandibular Disorders (TMD) injuvenileswithautisticspectrumdisorder(ASD). METHODS: Data included 165 juveniles diagnosed with ASD, allocated to you... OBJECTIVE: To evaluate the prevalence of oral habits, bruxism, and Temporomandibular Disorders (TMD) injuvenileswithautisticspectrumdisorder(ASD). METHODS: Data included 165 juveniles diagnosed with ASD, allocated to younger group aged 6 21 (n=86) and older group aged 13-21 (n=79). RESULTS: Sleep bruxism was reported by 26.7% in the younger group and by 5% in the older group. Awake bruxism was reported by 22% and 17.7%, respectively. Oral habits were reported by 43% of all participants, with similar rate in both groups. TMD related p ain was low in both groups (6.3% and 7% respectively). The influence of the COVID 19 pandemic on oral parafunction was moderate in the younger group (17.4%) and mild in the older group (8.6%), influence on bruxism was mild in both groups (5.8% and 2.5%, respectively). CONCLUSION: The prevalence of bruxism and oral parafunctions was similar to the reported in the literature for the general population.

Prevalence of temporomandibular disorders in the Brazilian population: A systematic review and meta-analysis.

Melo V, Monteiro L, Orge C … +4 more , Sales M, Melo J, Rodrigues B, Melo A

Cranio · 2025 Jul · PMID 37955100 · Publisher ↗

This systematic review aimed to assess the prevalence of temporomandibular disorders (TMD) in the Brazilian population, with studies that used the RDC/TMD or DC/TMD as diagnostic tools. A total of 6365 people from 11 stu... This systematic review aimed to assess the prevalence of temporomandibular disorders (TMD) in the Brazilian population, with studies that used the RDC/TMD or DC/TMD as diagnostic tools. A total of 6365 people from 11 studies were included. Sample mean age ranged from 12 to 69.5 years. The pooled prevalence of TMD was 33.6% (95% CI 31.5-35.8; I = 37.2). Prevalence of TMD was higher in females (37.0%) than in males (29.3%). Our results indicate that TMD is a prevalent condition across Brazil's territories. The results from this meta-analysis can help calculate more accurate sample sizes for future studies.
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