Ophthalmol Clin North Am
· 2005 Jun · PMID 15935287
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This article discusses ablative resurfacing, which is a powerful tool for rejuvenation of the aging face and treatment of a wide array of skin lesions. In the proper hands, it is a safe and effective way to treat many of...This article discusses ablative resurfacing, which is a powerful tool for rejuvenation of the aging face and treatment of a wide array of skin lesions. In the proper hands, it is a safe and effective way to treat many of the problems of photodamaged skin that surgery or nonablative methods cannot address.
Ophthalmol Clin North Am
· 2005 Jun · PMID 15935286
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Injectable fillers have become an important component of minimally invasive facial rejuvenation modalities. Their ease of use, effectiveness, low morbidity, and fast results with minimal downtime are factors that have ma...Injectable fillers have become an important component of minimally invasive facial rejuvenation modalities. Their ease of use, effectiveness, low morbidity, and fast results with minimal downtime are factors that have made them popular among patients. Soft tissue augmentation has evolved to a unique combination of medicine and art. A wide selection of available agents and new products, each one with unique properties, may be used alone or in combination. The physician acquires the tools to rebalance facial characteristics not only by filling wrinkles but also by having the ability to shape the face and restore bony contours and lines. Careful selection of candidates, realistic expectations, and an understanding of the limitations of fillers are crucial for a successful result.
Ophthalmol Clin North Am
· 2005 Jun · PMID 15935285
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This article describes the nonablative laser and light source technologies that are currently available for the rejuvenation of photodamaged skin. A brief overview of the etiology of solar skin damage is followed by an e...This article describes the nonablative laser and light source technologies that are currently available for the rejuvenation of photodamaged skin. A brief overview of the etiology of solar skin damage is followed by an explanation of how nonablative technologies induce repair of photoaged skin. An overview of the various light sources is provided, with particular attention to their mechanism of action and clinical use.
Ophthalmol Clin North Am
· 2005 Jun · PMID 15935284
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This article discusses the use of different chemical peels-very superficial, superficial, and medium depth. Once ophthalmologists understand the value and indications of this therapy, learn the techniques of application,...This article discusses the use of different chemical peels-very superficial, superficial, and medium depth. Once ophthalmologists understand the value and indications of this therapy, learn the techniques of application, and feel comfortable and confident with these methods, they should be able to treat the entire face.
Ophthalmol Clin North Am
· 2005 Jun · PMID 15935283
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Botox (and other botulinum toxins), injectable filling agents, chemical peeling agents, intense pulsed light devices, nonablative lasers, and radiofrequency instrumentation are discussed herein regarding their specific a...Botox (and other botulinum toxins), injectable filling agents, chemical peeling agents, intense pulsed light devices, nonablative lasers, and radiofrequency instrumentation are discussed herein regarding their specific applications to different facial areas for oculofacial rejuvenation.
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763205
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This article discusses primary lymphoma of the central nervous system, which is a variant of extranodal non-Hodgkin's lymphoma that arises from specific sites such as the brain, spinal cord, meninges, or eyes.This article discusses primary lymphoma of the central nervous system, which is a variant of extranodal non-Hodgkin's lymphoma that arises from specific sites such as the brain, spinal cord, meninges, or eyes.
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763204
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A broad spectrum of lymphomas can affect the eye and orbital tissues. This article discusses those that affect the orbit, lids, lacrimal gland, and conjunctiva.A broad spectrum of lymphomas can affect the eye and orbital tissues. This article discusses those that affect the orbit, lids, lacrimal gland, and conjunctiva.
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763203
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This article discusses the indications for intraocular tumor biopsy, the techniques used for obtaining material, and the approaches for analysis of these specimens.This article discusses the indications for intraocular tumor biopsy, the techniques used for obtaining material, and the approaches for analysis of these specimens.
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763202
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Retinal vascular tumors can be classified into four distinct clinical entities, which include retinal capillary hemangioma, retinal cavernous hemangioma, retinal arteriovenous communications (Wyburn-Mason syndrome), and...Retinal vascular tumors can be classified into four distinct clinical entities, which include retinal capillary hemangioma, retinal cavernous hemangioma, retinal arteriovenous communications (Wyburn-Mason syndrome), and retinal vasoproliferative tumor.
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763201
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Familial adenomatous polyposis (FAP) is a colon cancer predisposition syndrome in which hundreds to thousands of precancerous colonic polyp become evident at a mean age of 16 years (range, 7-36 years). By age 35 years, 9...Familial adenomatous polyposis (FAP) is a colon cancer predisposition syndrome in which hundreds to thousands of precancerous colonic polyp become evident at a mean age of 16 years (range, 7-36 years). By age 35 years, 95% of patients have polyps. Gardner syndrome is the eponym given to a subgroup of FAP with extracolonic manifestations, such as pigmented ocular fundus lesions that resemble congenital hypertrophy of the retinal pigment epithelium, among others.
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763200
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Choroidal hemangioma is an uncommon benign vascular tumor of the choroid that can be circumscribed or diffuse. Circumscribed choroidal hemangiomas are usually diagnosed between the second to fourth decade of life when th...Choroidal hemangioma is an uncommon benign vascular tumor of the choroid that can be circumscribed or diffuse. Circumscribed choroidal hemangiomas are usually diagnosed between the second to fourth decade of life when they cause visual disturbances owing to the development of an exudative retinal detachment. Circumscribed tumors occur sporadically, without any associated local or systemic anomalies. Diffuse choroidal hemangiomas are usually evident at birth and generally occur as a part of neuro-oculo-cutaneous hemangiomatosis (Sturge-Weber syndrome).
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763199
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Despite achieving great accuracy in correctly diagnosing uveal melanoma in the United States, mortality owing to this tumor has remained unchanged over a period of 25 years from 1973 to 1997. In general, the survival wit...Despite achieving great accuracy in correctly diagnosing uveal melanoma in the United States, mortality owing to this tumor has remained unchanged over a period of 25 years from 1973 to 1997. In general, the survival with metastatic uveal melanoma is poor, with a median survival of less than 6 months.
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763198
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This review provides a summary of the main objectives, significant design features, and major findings and achievements of the Collaborative Ocular Melanoma Study (COMS). It has been written by two ophthalmic oncologists...This review provides a summary of the main objectives, significant design features, and major findings and achievements of the Collaborative Ocular Melanoma Study (COMS). It has been written by two ophthalmic oncologists who were not part of the COMS study group; therefore, it represents an extramural view of the trial to supplement summaries published by the COMS investigators. Because the randomized design of the COMS was unique, no attempt is made to make any comparison with the results of previous non-controlled studies.
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763197
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This article describes surgical methods for resecting uveal melanoma, emphasizing techniques for preventing complications. Outcomes of surgery and the indications, contraindications, and controversies of resecting uveal...This article describes surgical methods for resecting uveal melanoma, emphasizing techniques for preventing complications. Outcomes of surgery and the indications, contraindications, and controversies of resecting uveal melanoma are discussed.
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763196
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Over the past two decades, radiotherapy has replaced enucleation as the standard treatment for uveal melanoma. Although this method does not alter survival, preservation of the globe and, in some instances, visual functi...Over the past two decades, radiotherapy has replaced enucleation as the standard treatment for uveal melanoma. Although this method does not alter survival, preservation of the globe and, in some instances, visual function, is achieved. This article presents the authors' and other investigators' experience with proton therapy.
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763195
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Thermotherapy by the transpupillary route is an effective outpatient eye-salvaging therapy for intraocular tumors. It does not require surgery, it can be repeated, and it does not affect the healthy structures of the eye...Thermotherapy by the transpupillary route is an effective outpatient eye-salvaging therapy for intraocular tumors. It does not require surgery, it can be repeated, and it does not affect the healthy structures of the eye. Thermotherapy by the transscleral route is under investigation and may have potential in the treatment of choroidal melanomas. The indications for chemoreduction, thermochemotherapy, and thermotherapy for retinoblastoma remain under investigation.
Singh AD, Damato B, Howard P
… +1 more, Harbour JW
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763194
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This article reviews the clinical genetics, cytogenetics, and molecular genetic aspects of uveal melanoma.This article reviews the clinical genetics, cytogenetics, and molecular genetic aspects of uveal melanoma.
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763193
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Melanomas of the ocular and adnexal structures comprise approximately 5% of all melanomas. The majority (85%) of ocular melanomas are uveal in origin; primary conjunctival and orbital melanomas are rare. The diagnosis of...Melanomas of the ocular and adnexal structures comprise approximately 5% of all melanomas. The majority (85%) of ocular melanomas are uveal in origin; primary conjunctival and orbital melanomas are rare. The diagnosis of uveal melanoma is made by clinical examination including indirect ophthalmoscopy and by ancillary studies such as fluorescein angiography and ultrasonography. Metastases to the liver develop within 15 years after the initial diagnosis and treatment in approximately 50% of patients with posterior uveal melanoma; however, clinically evident metastatic disease at the time of initial presentation is uncommon, indicating that there is early subclinical metastasis in most cases.
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763192
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This review provides an update on the current management of advanced retinoblastoma.This review provides an update on the current management of advanced retinoblastoma.
Ophthalmol Clin North Am
· 2005 Mar · PMID 15763191
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Retinoblastoma is the most common eye cancer in children. Pilot studies of chemotherapy for intraocular retinoblastoma have been reported by several groups, using different combinations, dosages, schedules, and durations...Retinoblastoma is the most common eye cancer in children. Pilot studies of chemotherapy for intraocular retinoblastoma have been reported by several groups, using different combinations, dosages, schedules, and durations of carboplatin, etoposide, or teniposide, with or without vincristine, and with or without cyclosporine to counteract multidrug resistance. All studies of chemotherapy for intraocular retinoblastoma have included consolidation by focal therapy, with or without radiation. Chemotherapy alone reduces tumor size but does not cure retinoblastoma. Focal therapy, consisting of photocoagulation, thermotherapy, cryotherapy, or brachytherapy, is necessary to consolidate chemotherapy response.