Advances In Mind-body Medicine[JOURNAL]
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200 papers
Impact of Yoga and Naturopathy in a Patient with Chronic Idiopathic Axonal Polyneuropathy Associated with Metabolic Syndrome and Rheumatoid Arthritis: A Case Report.
Sathiyavathi G, Vijay A, Keerthi P … +3 more , Suganthi S, Mooventhan A, Manavalan N
Adv Mind Body Med · 2026 May · PMID 41217900
BACKGROUND: Chronic idiopathic axonal polyneuropathy (CIAP) is a slowly progressive nerve disorder characterized by sensory or sensorimotor dysfunction, which is linked to type 2 diabetes mellitus, hypertension, and meta...
BACKGROUND: Chronic idiopathic axonal polyneuropathy (CIAP) is a slowly progressive nerve disorder characterized by sensory or sensorimotor dysfunction, which is linked to type 2 diabetes mellitus, hypertension, and metabolic syndrome. CIAP affects 75 to 125 per 100 000 people, with prevalence increasing in individuals over 60 years old. CASE STUDY: A 53-year-old female homemaker presented to our inpatient facility with complaints of chronic pain, burning sensation, and discoloration over both lower limbs, accompanied by numbness persisting for the past 10 years and a 15-year history of rheumatoid arthritis (RA). Despite adherence to the prescribed conventional treatment regimen (Metformin, Atorvastatin, Amlodipine, Rabeprazole sodium, Domperidone, Gabapentin, Nortriptyline hydrochloride, and Tramadol), as verified from her medical records, the patient's symptoms did not improve. INTERVENTION: The patient was provided with an integrative care for one month at our yoga and naturopathy (YN) hospital, where she received a structured lifestyle intervention comprising daily yoga sessions, a calorie-restricted plant-based diet, and adjunct naturopathic therapies such as massage, hydrotherapy, mud therapy, heliotherapy, and acupuncture with reflexology. RESULTS: Post-intervention assessments showed notable improvements in anthropometric measurements, inflammatory markers, lipid profile, the impact of RA on disease scores, complete blood counts, and quality of life. CONCLUSION: The findings highlight the potential of integrative medicine, combining IYN in addition to conventional medication, to address both physical and mental challenges in patients with CIAP associated with metabolic syndrome and RA. However, as this is a single case report, the findings cannot be generalized; hence, randomized controlled and pilot studies are recommended to validate the findings. KEYWORDS: case report, chronic idiopathic axonal polyneuropathy, integrative yoga and naturopathy, metabolic syndrome, rheumatoid arthritis.
Clinical Evaluation of an Herbal Unani Formulation (Itrifal-e-Ustukhuddus) in the Management of Migraine (Shaqeeqa): A Series of Case Reports.
Shah HA, Khan S, Wani KR … +1 more , Wani UH
Adv Mind Body Med · 2026 May · PMID 41217899
BACKGROUND: Migraine is a disabling neurovascular disorder with few targeted, tolerable, and effective treatments. It is characterized by acute headaches that substantially impair patients' quality of life and work perfo...
BACKGROUND: Migraine is a disabling neurovascular disorder with few targeted, tolerable, and effective treatments. It is characterized by acute headaches that substantially impair patients' quality of life and work performance. Migraine patients frequently require long-term treatment due to frequent attacks or a chronic course of the condition. Many people still suffer from side effects or insufficient alleviation despite advances in mainstream treatment, which has led to interest in alternative remedies. This case series evaluates the efficacy of Itrifal-e-Ustukhuddus (an herbal Unani formulation) in chronic migraine. METHODS: Four cases of diagnosed migraine patients were treated with the Unani formulation, Itrifal-e-Ustukhuddus, for 8 weeks. The primary outcome measures included improvements in pain intensity (VAS), migraine disability assessment (MIDAS), and migraine-specific quality of life (MSQOL). RESULTS: All the patients showed notable improvement in symptoms and quality of life. VAS scores reduced from 9/10 to 3/10, 8/10 to 2/10, 8/10 to 3/10, and 9/10 to 2/10, indicating pain relief. Additionally, more than 50% improvement was observed in MIDAS and MSQOL scores, reflecting a reduction in migraine-associated disability and improved quality of life, respectively. CONCLUSION: With no side effects noted, the Unani formulation showed encouraging effectiveness in treating chronic migraine. However, thorough prospective clinical studies are recommended to confirm its scientific validity and possible incorporation into standard medical practice. KEYWORDS: chronic migraine, Itrifal-e-Ustukhuddus, Unani medicine, alternative therapy, case series, quality of life.
Yoga for Eye Disorders-A Systematic Review.
Abraham L, George S, Bhat R
Adv Mind Body Med · 2026 May · PMID 41217898
BACKGROUND: Eye disorders significantly impair quality of life, productivity, and overall well-being. With the increasing interest in integrative medicine, yoga has been explored as a potential adjunct therapy for ocular...
BACKGROUND: Eye disorders significantly impair quality of life, productivity, and overall well-being. With the increasing interest in integrative medicine, yoga has been explored as a potential adjunct therapy for ocular conditions. OBJECTIVE: This systematic review aimed to examine the efficacy of yoga-based interventions in managing glaucoma, refractive errors, dry eye disease, and visual strain. METHODS: A comprehensive literature search of MEDLINE/PubMed (January 2000 to April 2025) identified experimental studies that evaluated the effects of yoga on eye disorders. Fourteen eligible studies were included. The risk of bias was assessed using Cochrane RoB 2 and ROBINS-I tools, and the PRISMA guideline was followed. RESULTS: The strong evidence supports meditation and pranayama as effective adjuncts in reducing intraocular pressure in glaucoma, potentially via stress modulation and autonomic regulation. Limited and inconclusive evidence has been found regarding the effects of yoga on myopia and dry eye disease. Methodological limitations, such as small sample sizes, short intervention durations, and subjective outcome measures, were commonly observed. CONCLUSION: Yoga is a promising adjunct therapy for glaucoma management. However, more rigorous, long-term, randomized trials with standardized protocols and objective outcomes are needed to validate its role across diverse ocular conditions. KEYWORDS: eye health, eye disorders, glaucoma, myopia, dry eye disease, yoga, meditation, pranayama, systematic review.
Outcomes Assessment of a Novel, Multisite, School-Based Inclusive Instrumental Music Program with Peer-Mentoring for Students with Intellectual and Developmental Disabilities.
Bittman B, White D, Bunstein T … +1 more , Duty J
Adv Mind Body Med · 2026 Jan · PMID 41118625
BACKGROUND: Psychosocial skills developed in an inclusive learning environment can benefit students with intellectual and developmental disabilities (IDD). However, the inclusion of students with disabilities in classroo...
BACKGROUND: Psychosocial skills developed in an inclusive learning environment can benefit students with intellectual and developmental disabilities (IDD). However, the inclusion of students with disabilities in classroom-based learning environments often remains challenging. OBJECTIVE: This multisite, cohort-based observational study, spanning a school year (August-September through May-June), examined the psychosocial development of 60 new musicians-students with IDD who participated in an inclusive school-based instrumental music program with peer mentoring for the first time. METHODS: Students from eight public schools participated in the United Sound instrumental music program for an average of 45 minutes per week throughout the school year. Special education teachers assigned volunteer student musicians, referred to as peer mentors, to work closely with and support new musicians who were trained to play an instrument and perform in ensembles, bands, and orchestras. Peer-mentor training by special education teachers focused on the established United Sound curriculum and three key strategies: Communicate, Modify, and Empower. New musicians underwent psychosocial evaluations conducted by special education teachers familiar with them at the beginning and end of the school year, utilizing a novel, newly developed 10-measure direct observation assessment tool. RESULTS: Statistically significant findings were noted in pre- and post-tests across all measures. Improvements over the baseline ranged from 8.2% to 29.8%. These include willingness to participate in non-preferred activities (9.8%), peer appropriate communications (9.1%), positive peer interactions (8.2%), empathy (14.6%), appropriate assertiveness (13.0%), impulse control (24.7%), self-confidence (18.8%), pride (13.2%), resilience (24.5%), and the ability to endure stressful environments (29.8%). CONCLUSION: This unique, inclusive instrumental music program with peer mentoring should be considered an integral component of the educational framework in all schools, as it has the potential to improve the psychosocial development and the future potential of students with IDD. KEYWORDS: inclusive music education, intellectual and developmental disabilities, peer mentoring, psychosocial outcomes.
Effect of a Year-long Yoga-Based Lifestyle Intervention on Glycemic Control, Body Weight, Psychological Health, and Imaging Biomarkers in Adults with Type 2 Diabetes: A Randomized Controlled Trial.
Bhargav H, Bista S, Jasti N … +11 more , Chikkanna U, Kumar V S, Kumar R K, Varmbally S, Srikanta S, Nagarathna R, Padmavati R, Kusneniwar G, Singh NK, Gangadhar BN, Manohar KN
Adv Mind Body Med · 2026 May · PMID 41118624
BACKGROUND: Type 2 diabetes mellitus is a major global health challenge, adversely affecting the quality of life. OBJECTIVE: To evaluate a year-long yoga-based lifestyle intervention versus physical exercise and health e...
BACKGROUND: Type 2 diabetes mellitus is a major global health challenge, adversely affecting the quality of life. OBJECTIVE: To evaluate a year-long yoga-based lifestyle intervention versus physical exercise and health education for glycemic control and comprehensive health outcomes in adults with Type 2 Diabetes Mellitus. STUDY DESIGN: Two-arm, prospective, assessor-blinded, randomized controlled trial with a parallel-group superiority design and a 1:1 allocation ratio. PARTICIPANTS: 160 adults with Type 2 Diabetes Mellitus (mean age 53.34±8.97 years; 84 males) were randomized to yoga-based lifestyle (n=80) or physical exercise and health education (n=80) groups. INTERVENTION: The yoga-based group received supervised yoga practice (1 hour/day, 5 days/week) for 4 weeks, followed by 11 months of tele-supervised practice with weekly yoga philosophy discussions. The physical exercise group received matched physical exercise and health education sessions. Assessments were performed at baseline, 6 months, and 1 year. RESULTS: Although both interventions significantly reduced glycated hemoglobin levels and waist-hip ratio at 12 months, the yoga-based group demonstrated superior glycated hemoglobin reduction compared to theexercise group at 6 months (mean estimated difference of 0.80 unit greater reduction) and 1 year (mean estimated difference of 1.25 unit greater reduction), corresponding to a 22.06% greater decrease in HbA1C levels over the course of 1 year.. The yoga-based group also showed significant improvements in postprandial glucose, depression scores, and body mass index at 1 year compared to the exercise group. The yoga-based group showed significant improvements in the energy balance of several organs, including overall balance, right and left organ balance, digestive system balance, adrenal balance, cerebral cortex balance, and stress reduction compared to the exercise group. Additionally, the yoga-based lifestyle group exhibited significantly reduced medication use scores at 12 months. CONCLUSION: Yoga-based lifestyle interventions show superior efficacy over standard physical exercise programs for diabetes management, demonstrating improvements in glycemic control, psychological health, and novel biomarkers. These findings support integrating yoga interventions into comprehensive diabetes care, although further mechanistic studies are warranted. KEYWORDS: yoga, type 2 diabetes mellitus, glycemic control, glycated hemoglobin, depression, postprandial plasma glucose, thermal imaging, gas discharge visualization.
Supporting Renal Function and Electrolyte Balance in Chronic Kidney Disease through Yoga and Naturopathy Lifestyle: A Single-Group Pre-Post Study.
Deepa Y, Vijay A, Prashanth A … +4 more , Prakash Raj S, Christa E, Manavalan N, Mooventhan A
Adv Mind Body Med · 2026 Mar · PMID 41118623
BACKGROUND: Chronic kidney disease (CKD) is defined as an abnormality in kidney structure or function, persisting for more than three months. It is a multifaceted condition causing renal dysfunction and progression to en...
BACKGROUND: Chronic kidney disease (CKD) is defined as an abnormality in kidney structure or function, persisting for more than three months. It is a multifaceted condition causing renal dysfunction and progression to end-stage kidney disease. Complementary and alternative medicine, including yoga and naturopathy, has demonstrated effectiveness in treating and preventing several conditions linked to CKD. OBJECTIVE: This study aims to investigate the impact of yoga and naturopathy on renal function and serum electrolytes in CKD patients. MATERIALS AND METHODS: 50 patients diagnosed with CKD underwent yoga and naturopathy-based lifestyle modification for 30 days. Renal function (including urea, creatinine, blood urea nitrogen (BUN), uric acid, glomerular filtration rate (GFR)) and serum electrolytes (including calcium, potassium, sodium, phosphorus, chloride, and bicarbonate) were assessed before and after the intervention. RESULTS: Results of the study showed a significant reduction in urea, creatinine, BUN, potassium, phosphorus (P < .001 for all variables), sodium (P < .005) and chloride (P < .05), and an increase in GFR and calcium (P < .001), with no significant changes in uric acid (P = .268), and bicarbonate (P = .112) in the post-test assessments compared to pre-test assessments. CONCLUSION: Yoga and naturopathy-based lifestyle modification help to improve the renal function of CKD patients. However, the small sample size and lack of a control group limit the scope of this study. Hence, further randomized controlled trials with a larger sample size are recommended to validate the results of the study. KEYWORDS: alternative medicine, chronic kidney diseases, hydrotherapy, lifestyle medicine, naturopathy, nutrition, yoga.
Yoga as a Tool for Reducing Anxiety and Enhancing Mindful Attention in Chess Olympiad Players: A Mixed-Method Study.
Mooventhan A, Arunthathi R, Suryapraba S … +6 more , Venugopal V, Kanimozhi KK, Nivethitha L, Vijay A, Kahlilsubramanian K, Manavalan N
Adv Mind Body Med · 2026 May · PMID 41118622
BACKGROUND: The Chess Olympiad is a grand international chess event, which possibly involves immense performance anxiety and stress. Yoga is widely used as a stress management tool across different specialties. However,...
BACKGROUND: The Chess Olympiad is a grand international chess event, which possibly involves immense performance anxiety and stress. Yoga is widely used as a stress management tool across different specialties. However, there is a lack of studies evaluating the impact of yoga on chess players. The current study aims to assess the effect of yoga on the physical, mental, and social dimensions of health in international chess players during the Chess Olympiad. MATERIALS AND METHODS: In this mixed-method study, a total of 148 chess players participated. Qualitative (n=148) and quantitative data (n=113) were collected using a survey form and questionnaires [Spielberger State-Trait Anxiety Inventory (STAI) and the Mindful Attention Awareness Scale (MAAS)], respectively. RESULTS: Results showed a widespread awareness of yoga among players, with a majority lacking prior experience. Participants perceived yoga positively, noting benefits such as improved physical health, enhanced mental focus, and increased social adaptability. Statistical analysis demonstrated significant decreases in STAI score (z = 7.900; P < .001) and MAAS score (z = 8.300; P ≤ .001) after a yoga session compared to before the session. CONCLUSION: This study suggests that yoga has the potential to improve the overall well-being and preparedness for performance among international chess players. Future research should explore the long-term effects and validate these findings using larger sample sizes and biochemical measures to elucidate the efficacy of yoga practice in optimizing mental and physical states, which is crucial for competitive sports. KEYWORDS: chess olympiad, mindfulness, spielberger state-trait anxiety inventory, survey, mindful attention awareness scale, yoga.
Effect of Six Months of Gallbladder Flush on Size and Symptoms of A Patient With Cholelithiasis: A Case Report.
Uma Devi K, Saravanan V, Vijaya Bharathi E … +1 more , Mooventhan A
Adv Mind Body Med · 2026 Mar · PMID 40982748
BACKGROUND: Cholelithiasis is a chronic recurrent hepatobiliary disease caused by impaired metabolism of cholesterol, bilirubin, and bile acids. A gallbladder flush (GBF) involves consuming olive oil, lemon juice, and ap...
BACKGROUND: Cholelithiasis is a chronic recurrent hepatobiliary disease caused by impaired metabolism of cholesterol, bilirubin, and bile acids. A gallbladder flush (GBF) involves consuming olive oil, lemon juice, and apple cider vinegar, along with dietary restrictions. Previous studies have shown that GBF helps dissolve stones; however, it is provided only for a short duration and does not incorporate dietary modifications. Hence, this case report aims to evaluate the effect of repeated GBF sessions combined with an apple-based diet on a patient with cholelithiasis. METHODS: A 59-year-old male who was diagnosed with cholelithiasis in 2020 visited our hospital on September 1st, 2021. He presented with complaints of nausea and abdominal discomfort after eating, regurgitation, and constipation for the past 6 months. He was on conventional medications (Pantoprazole (40 mg), Domperidone (10 mg) twice a day before food, Biscodyl (5 mg) at night, and Urocidol (150 mg) twice a day, after food). The patient underwent 3 sessions of GBF over the period of 6 months. Ultrasonography (abdomen) was taken before and after each session. RESULTS: The study's findings showed a reduction in gallstone size from 16 mm to 6.5 mm after 1st session, 6.5 mm to 5 mm after 2nd session, and fragmentation into multiple smaller stones, with the largest measuring 3.6 mm after 3rd session. After 1 month of intervention, the patient's symptoms subsided, and no adverse events were reported. CONCLUSION: GBF was effective in reducing the symptoms and the size of the stone in a patient with cholelithiasis. Since this is a single-case study, the generalizability of its findings may be limited. Further clinical trials with a larger sample size are recommended to validate the study's results and assess its applicability in a broader population. KEYWORDS: cholelithiasis, gallstones, gallbladder flush, naturopathy, case report.
Immediate Effect of Pranayama on Pulmonary Function in Healthy Adults: An Experimental Study.
Kakkar S, Sharma V, Kumar U … +2 more , Basu N, Jaiswal G
Adv Mind Body Med · 2026 Mar · PMID 40982747
BACKGROUND: Yoga, a holistic mind-body practice, has gained recognition for its potential health benefits, including improvements in pulmonary function. However, limited research has focused on the immediate effects of a...
BACKGROUND: Yoga, a holistic mind-body practice, has gained recognition for its potential health benefits, including improvements in pulmonary function. However, limited research has focused on the immediate effects of a single yoga session on pulmonary parameters. This study aims to investigate the immediate impact of a 60-minute yoga session on pulmonary function in healthy adults. METHODOLOGY: A total of 20 healthy adults from Amity University participated in a single-group pretest-posttest design study. Participants, with a mean age of 19.58±1.45 years, engaged in a 60-minute yoga session focused on pranayama techniques. Pulmonary function assessments, including Forced Vital Capacity (FVC), Forced Expiratory Volume in one second (FEV1), and Peak Expiratory Flow Rate (PEFR), were conducted using a spirometer before and immediately after the yoga session. Paired t-tests were employed to compare pretest and posttest values of pulmonary function parameters. RESULTS: The analysis revealed a significant increase in all three pulmonary function parameters following the yoga session. Mean FVC increased from 2.77 ± 1.62 L to 3.46 ± 2.18 L (P = .004), FEV1 from 1.82 ± 1.09 L to 2.31 ± 1.35 L (P = .007), and PEFR increased from 2.33 ± 1.45 L to 3.62 ± 2.58 L (P = .013). These findings indicate an immediate positive effect of yoga on pulmonary function. CONCLUSION: The observed improvements in pulmonary function parameters suggest that a single 60-minute yoga session can have immediate beneficial effects on respiratory health in healthy adults. Integrating yoga into daily routines may offer a simple yet effective approach to promote respiratory health. Further research should explore the long-term effects of yoga on pulmonary function and its efficacy as an adjunct therapy for respiratory disorders. KEYWORDS: yoga, Pranayama, spirometer, respiratory muscle strength, pulmonary function.
Effect of 4 Weeks of Yogic-based Paschimottanasana Practice on Sit-and-Reach Test and Goniometer Measurements among Healthy Participants: A Randomized Controlled Trial.
Thapa R, Chandrabanshi A, Singh A … +1 more , Kumar R
Adv Mind Body Med · 2026 Mar · PMID 40864604
BACKGROUND: Flexibility is a vital component of physical fitness, influencing movement efficiency and reducing the risk of injury. Hamstring tightness, a preventable issue, impairs flexibility and athletic performance. P...
BACKGROUND: Flexibility is a vital component of physical fitness, influencing movement efficiency and reducing the risk of injury. Hamstring tightness, a preventable issue, impairs flexibility and athletic performance. Paschimottanasana is a yogic posture purported to improve hamstring flexibility; however, limited empirical evidence supports its effectiveness. AIM: The study aims to evaluate the effectiveness of Paschimottanasana in improving hamstring flexibility among healthy young adults. MATERIALS AND METHODS: A total of 150 healthy participants aged 18 to 28 years from a university in North India were randomly assigned into two groups using the chit method. The participants were divided into an intervention group and a control group. Both groups engaged in 20-minute yogic practices daily for four weeks, six days per week. The intervention group practiced 16 minutes of Sukshma Vyayama (loosening exercises) followed by 4 minutes of Paschimottanasana (Seated Forward Bend Pose), while the control group practiced 16 minutes of Sukshama Vyayama followed by 4 minutes of Savasana (Corpse Pose). Baseline and post-intervention data were collected and analyzed. RESULTS: At the end of 4 weeks, the intervention group demonstrated a statistically significant improvement in lumbar flexion angle, reducing from 80.24±7.24 to 68.86±8.66 degrees (P < .001); the control group showed minimal change (81.70±7.56 to 79.56±7.95), which was not statistically significant (P > .05). Sit-Reach-Test scores also improved significantly in the intervention group compared to the control group. CONCLUSION: Paschimottanasana practice significantly improved hamstring flexibility within 4 weeks, while Sukshma Vyayama alone resulted in only minor improvements. KEYWORDS: yoga, paschimottanasana, hamstring flexibility, goniometer, sit-reach-test, straight leg raise.
Mind-Body Healing: Evaluating the Acharya Technique for Low Back Pain in Middle-Aged Women.
Meshram U, Kaur J
Adv Mind Body Med · 2026 Mar · PMID 40864603
BACKGROUND: Low back pain (LBP) is a prevalent issue affecting a significant portion of the global population, impacting the quality of life, especially in menopausal females. AIM: This study aimed to assess the effectiv...
BACKGROUND: Low back pain (LBP) is a prevalent issue affecting a significant portion of the global population, impacting the quality of life, especially in menopausal females. AIM: This study aimed to assess the effectiveness of the Acharya Technique in managing LBP among late middle-aged females. METHODOLOGY: The study used a pre-experimental research design. Data were collected using structured questionnaires from 60 females aged 45-64 years, selected through Convenience sampling, covering demographic variables, clinical characteristics, intensity of LBP, and the Roland-Morris Disability Questionnaire. INTERVENTION: The intervention consisted of the Acharya Technique, a structured sequence of stretching exercises targeting the lower back, practiced for 3-5 minutes daily over 15 days. Each session included five specific movements, with each step held for approximately 30 seconds. RESULTS AND DISCUSSION: The LBP intensity significantly reduced post-intervention (P < .05), indicating the effectiveness of the Acharya Technique in mitigating LBP among late middle-aged females. The average low back pain score of 4.7 in the pre-test reduced to 2.5 in the post-test. The t value was 19.8 with 59 degrees of freedom. Thus, LBP significantly reduced after the Acharya Technique intervention. CONCLUSION: The study findings suggest that the Acharya Technique is an effective intervention for managing LBP among females, which can be taught to them at home. KEYWORDS: mind-body medicine, low back pain, acharya technique, late middle-aged females, yoga.
Tailored Multimodal Therapeutic Regimen for Neurodermatitis: Alleviating Skin Excoriation Urges through an Interdisciplinary Approach.
Khan R, Upendra S
Adv Mind Body Med · 2026 Mar · PMID 40864602
BACKGROUND: Neurodermatitis significantly impairs quality of life due to the chronic itch-scratch cycle driven by compulsive excoriation behavior. OBJECTIVE: This study evaluated the effectiveness of a tailored therapeut...
BACKGROUND: Neurodermatitis significantly impairs quality of life due to the chronic itch-scratch cycle driven by compulsive excoriation behavior. OBJECTIVE: This study evaluated the effectiveness of a tailored therapeutic regimen in reducing excoriation behavior and improving patient outcomes. RESEARCH DESIGN: Quasi-experimental study conducted over six weeks. SETTING: The study was conducted at selected dermatology clinics in Pune, Maharashtra, India. PARTICIPANTS: Sixty adult participants diagnosed with neurodermatitis were recruited and divided into experimental (n=30) and control (n=30) groups using multistage cluster sampling. INTERVENTION: The intervention group received a structured, patient-centered therapeutic kit including an instructional pamphlet. PRIMARY OUTCOME MEASURES: Pre- and post-intervention assessments were conducted using the 5-D Pruritus Scale. RESULTS: Baseline mean urge score in the experimental group was 17.8 (SD = 1.3), indicating severe to unbearable excoriation tendencies. Post-intervention, the experimental group's mean urge score significantly decreased to 12.2 (SD = 1.1), indicating a shift toward moderate urge levels (P < .001). In contrast, the control group showed no significant improvement. Additionally, participants in the intervention group reported enhanced quality of life scores and average satisfaction with the regimen. The tailored therapeutic regimen significantly reduced excoriation behavior among individuals with neurodermatitis. CONCLUSION: These findings support the integration of behavioral and dermatological strategies in routine clinical management to disrupt the itch-scratch cycle and improve patient well-being. KEYWORDS: tailored multimodal therapeutic regimen, neurodermatitis, excoriation, excoriation behavior alleviation.
Impact Of Spinal Flexion and Extension-Based Yoga Asanas on Autonomic Variables in Experienced Yogic Practitioners: Study Protocol for a Randomized Crossover Trial.
Shetty S, Manjunath NK, Shetty P … +2 more , Ramaswamy KA, Nanjeshgowda HL
Adv Mind Body Med · 2026 Mar · PMID 40864601
BACKGROUND: The autonomic nervous system (ANS) is a complex network responsible for maintaining homeostasis. Yoga, as a traditional mind-body intervention, is known to modulate autonomic function in both healthy and clin...
BACKGROUND: The autonomic nervous system (ANS) is a complex network responsible for maintaining homeostasis. Yoga, as a traditional mind-body intervention, is known to modulate autonomic function in both healthy and clinical populations. However, the differential effects of forward versus backward-bending yoga asanas on autonomic parameters remain unexplored. OBJECTIVES: This study aims to investigate and compare the effects of spinal flexion (forward bending) and extension (backward bending) yoga postures on autonomic variables in experienced yogic practitioners. METHODS: This single-group, randomized crossover trial will recruit 40 healthy volunteers aged 20-25 years with at least two years of yoga experience. Participants will be randomly assigned to practice either forward-bending or backward-bending postures on Day 1, followed by crossover to the alternate intervention on Day 2. Each session will include a 30-minute break between postures. Outcome measures, including electrocardiogram (ECG), surface electromyography (sEMG), electrogastrogram (EGG), and galvanic skin resistance (GSR), will be recorded at baseline, during, and after the intervention to assess autonomic, muscular, and gastrointestinal responses. Data will be subjected to appropriate statistical analyses based on distribution and type, using parametric or non-parametric tests as applicable. DISCUSSION: This protocol outlines a rigorous approach to evaluating posture-specific autonomic responses in yoga practitioners. The findings are expected to inform the design of tailored yoga interventions for autonomic modulation. KEYWORDS: autonomic function, homeostasis, spinal extension, spinal flexion, yoga, study protocol.
Analysis of Trauma-Informed and Trauma-Sensitive Mindfulness-based Yoga Therapies.
Shetty L, Reddy GG, Chandrababu R … +2 more , Amuthan A, Rawat S
Adv Mind Body Med · 2026 Jan · PMID 40748024
ABSTRACT: Trauma can have a significant and long-lasting impact on people; it frequently shows up as anxiety, sadness, and post-traumatic stress disorder (PTSD). The interaction between the physiological and psychologica...
ABSTRACT: Trauma can have a significant and long-lasting impact on people; it frequently shows up as anxiety, sadness, and post-traumatic stress disorder (PTSD). The interaction between the physiological and psychological reactions to trauma emphasizes the significance of holistic healing approaches. Studies suggest that conventional therapeutic approaches might not adequately tackle the intricacies of trauma, which has led to the investigation of body-based therapies like yoga. Trauma-Informed Yoga (TIY) places a strong emphasis on comprehending how trauma affects the body and mind while fostering safety and security that values empowerment, choice, and building trust. Trauma-Sensitive Yoga (TSY) emphasizes physical practices that can be fundamental in healing by encouraging awareness and a connection to the body. This method integrates psychological therapy to assist people in navigating their trauma in a safe environment. Both strategies aim to create a secure and encouraging environment that promotes healing via bodily awareness and mindfulness. In clinical research, the relative effectiveness of different approaches is poorly understood. The present work assesses TIY and TSY therapies based on trials registered on ClinicalTrials.gov. PTSD, anxiety, and depression results were reported in randomized controlled trials (RCTs) that were published in the past ten years. The results show that TIY and TSY have unique benefits. It is challenging to validate the efficacy of these approaches based on current clinical outcomes. The efficacy of these approaches is specific to trauma history and intensity, gender, age, duration, and mode of practice. Further clinical studies focusing on these variables would help better understand the approaches in clinical settings. KEYWORDS: trauma-informed, trauma-sensitive, yoga intervention, yoga clinical trials.
Bridging the Mind-Heart Connection: Advancing Cardiovascular Care Through Mental Health Integration.
Sharma A, Kalal N, Sharma SK
Adv Mind Body Med · 2026 Jan · PMID 40748023
ABSTRACT: As the understanding of mind-body connections deepens, the importance of addressing psychological factors within cardiovascular care has gained recognition. This review examines the necessity for cardiovascular...
ABSTRACT: As the understanding of mind-body connections deepens, the importance of addressing psychological factors within cardiovascular care has gained recognition. This review examines the necessity for cardiovascular doctors to broaden their knowledge in psychology and mental health to optimize patient outcomes. Psychological stress, depression, and anxiety have profound effects on cardiovascular health, often exacerbating symptoms, influencing recovery rates, and affecting treatment adherence. Consequently, integrating psychological knowledge can enhance the efficacy of cardiovascular care, addressing both physiological and psychological facets of health. KEYWORDS: mind-body, heart mental health, cardiovascular care, psychological stress, depression, anxiety.
Fusion of Artificial Intelligence and Mind-Body Medicine for Holistic Health: A Systematic Review.
Nadaf H, Jabade M
Adv Mind Body Med · 2026 Jan · PMID 40748022
BACKGROUND: Mind-Body Medicine (MBM) is an integrative healthcare approach that employs practices such as meditation, yoga, biofeedback, and Tai Chi to promote well-being. Artificial Intelligence (AI) is increasingly use...
BACKGROUND: Mind-Body Medicine (MBM) is an integrative healthcare approach that employs practices such as meditation, yoga, biofeedback, and Tai Chi to promote well-being. Artificial Intelligence (AI) is increasingly used in MBM to offer data-driven, real-time, and adaptive interventions. While the impact of AI on diagnostics and treatment in healthcare is well documented, its efficacy and challenges in MBM are less studied. OBJECTIVE: This study critically evaluates the effectiveness of AI-based MBM interventions in improving mental and physiological health outcomes, compares AI-based MBM with traditional MBM interventions, compares the performance of different AI models in MBM interventions, and identifies data privacy challenges, AI explainability, and ethical concerns in AI-based MBM interventions. METHODS: The literature search was conducted across five major academic databases: PubMed, Scopus, Web of Science, IEEE Xplore, and Google Scholar. Peer-reviewed journal articles on AI-based MBM interventions with quantitative health outcomes in stress levels, heart rate variability (HRV), electroencephalography (EEG) activity, anxiety, or depression were included. Meta-analysis was performed using Cohen's d to determine effect sizes, and statistical heterogeneity was estimated using I² statistics. RESULTS: 15 studies were selected for final analysis based on inclusion and exclusion criteria. AI-based MBM interventions were found to significantly improve both mental and physiological health outcomes, such as cortisol levels, anxiety and depression scores, HRV, and EEG alpha wave activity. Although AI-assisted MBM was found to outperform the traditional approach in personalization, engagement, and adherence rate, concerns exist about data privacy, algorithmic bias, AI explainability, and user trust issues. Furthermore, AI-driven interventions showed variability in effectiveness depending on the training datasets, with a potential risk of bias in AI-generated recommendations. CONCLUSION: AI-driven MBM interventions have immense scope in upgrading classic mind-body techniques by delivering truly personalized, adaptive, and timely interventions. However, further research and consideration are warranted to overcome ethical concerns and biases. KEYWORDS: Artificial Intelligence, Mind-Body Medicine, Holistic Health, Biofeedback, Meditation, Yoga, Tai Chi.
Vitality and Metabolic Responses to Integrated Naturopathy and Yogic Interventions in Individuals with Metabolic Syndrome: A Randomized Controlled Trial.
Shishira R, Shashikiran HC, Sujatha KJ … +2 more , Shetty P, Nanjeshgowda HL
Adv Mind Body Med · 2026 Jan · PMID 40748021
BACKGROUND: Metabolic Syndrome is a group of interrelated physiological, biochemical, clinical, and metabolic factors that significantly increase the risk of type 2 diabetes, cardiovascular diseases, and overall mortalit...
BACKGROUND: Metabolic Syndrome is a group of interrelated physiological, biochemical, clinical, and metabolic factors that significantly increase the risk of type 2 diabetes, cardiovascular diseases, and overall mortality. This study aims to evaluate the impact of naturopathy and yogic interventions on vitality and metabolic responses in patients with metabolic syndrome. METHODS: This study is a single-center randomized controlled trial conducted at the Nature Cure and Yoga Centre in Karnataka state of Southern India. 76 Participants diagnosed with metabolic syndrome, according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria, were randomly assigned in a 1:1 ratio to either the intervention (n=38) or control group (n=38). The intervention group received intensive naturopathy and yoga treatments for 10 days, while the control group was not provided with any specific interventions. Primary outcomes were assessed through measurements of heart rate variability, blood pressure, lipid profile, anthropometric data, a vitality questionnaire (by Ryan and Frederick, 1997), and the Framingham Risk Score conducted at baseline and after 10 days of intervention. RESULTS: The intervention group demonstrated significant improvements in body mass index, systolic and diastolic blood pressure, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and fasting blood glucose compared to the control group (P < .05). Furthermore, participants in the intervention group reported increased vitality (P < .05) compared to the control group. Also, vitality scores showed a positive correlation with SDRR (ρ = -0.38, P = .02) and negative correlation with HR (ρ = -0.35, P = .04) and FRS (ρ = -0.3, P = .01). CONCLUSION: Naturopathy and yoga significantly improved metabolic markers, cardiovascular risk, and vitality in patients with metabolic syndrome. The intervention showed favorable changes in BMI, blood pressure, lipids, and glucose. Vitality correlated positively with HRV and inversely with heart rate and Framingham Risk Score. These findings support integrative therapies as beneficial adjuncts in metabolic syndrome management. KEYWORDS: metabolic syndrome, naturopathy, yoga, vitality.
Phase 1 Pulmonary Rehabilitation: A Comparative Study Of Inspiratory Muscle Training And Autogenic Drainage.
Nair V, Naik V, Gautam S
Adv Mind Body Med · 2026 Jan · PMID 40748020
BACKGROUND: Reportedly, around 6.3% of individuals over the age of 30 in Asia-Pacific countries suffer from stages II and III chronic obstructive pulmonary disease (COPD). Among various rehabilitation strategies, Inspira...
BACKGROUND: Reportedly, around 6.3% of individuals over the age of 30 in Asia-Pacific countries suffer from stages II and III chronic obstructive pulmonary disease (COPD). Among various rehabilitation strategies, Inspiratory Muscle Training (IMT) and Autogenic Drainage (AD) are emerging as effective interventions aimed at improving respiratory function and symptom control. This study aimed to evaluate and compare the effects of IMT and AD in hospitalized COPD patients, focusing on outcomes related to lung function, quality of life, bronchial hygiene, and respiratory muscle performance. METHODS: Out of 59 screened subjects, 40 met the inclusion criteria and were enrolled. They were randomly allocated into two groups: Group A received AD and Group B underwent IMT. Both groups participated in a structured intervention protocol for two weeks. A total of 35 participants completed the study. RESULTS: Post-intervention, both groups showed significant improvement in forced vital capacity (FVC): Group A (-0.61 ± 0.52; P = .0089) and Group B (-0.46 ± 0.67; P = .0233). Chest expansion at Point B (measured at nipple level ) increased significantly in both groups (P = .0002) and at Point A (measured at axillary level) in Group A (P = .0283). While other outcomes, namely FEV1/FVC (P = .5), St George Respiratory Questionnaire (P = .6), Maximal Inspiratory Pressure (P = .6), and 6-minute walk test (P = .9), demonstrated positive trends, although not statistically significant. CONCLUSION: Both the AD and IMT groups demonstrated statistically significant increases in FVC and chest expansion following the intervention, especially at the axillary level in the AD group and at the nipple level in both groups. Although not statistically significant, other variables such as the FEV1/FVC ratio, quality of life scores, inspiratory pressure, and functional exercise capacity demonstrated clinically useful trends. KEYWORDS: chronic obstructive pulmonary disease, respiratory therapy, rehabilitation, pulmonary function tests, inspiratory muscle training, autogenic drainage.
Effective Management of Venous Ulcer with Leech Therapy: A Case Report.
Wani KR, Shah HA, Ashraf A … +4 more , Nazir A, Mehraj M, Ansari AN, Nayab M
Adv Mind Body Med · 2025 Fall · PMID 40700533
BACKGROUND: Venous ulcers represent the most common type of leg ulcer and a debilitating consequence of chronic venous insufficiency. If not appropriately managed, these ulcers can progress to serious complications such...
BACKGROUND: Venous ulcers represent the most common type of leg ulcer and a debilitating consequence of chronic venous insufficiency. If not appropriately managed, these ulcers can progress to serious complications such as gangrene and limb amputation, causing a significant decline in the patient's quality of life. In the Unani system of medicine, such ulcers are managed using various non-pharmacological interventions categorized under Ilāj bi'l Tadbīr (regimenal therapies). Among these, Ta'līq al-'Alaq (leech therapy) is frequently used for its efficacy in managing ulcers. This case study presents the treatment of a venous ulcer using leech therapy. CASE PRESENTATION: A 42-year-old male presented with complaints of an ulcer on the right lower leg near the medial malleolus, accompanied by pain, discharge, and darkening of the skin in the right lower limb. Five sessions of leech therapy were conducted at 10-day intervals over 50 days, specifically on the 0th, 10th, 20th, 30th, and 40th days. In each session, three medicinal leeches (Hirudo medicinalis) were applied to the ulcer site, and the site was assessed based on the wound area size, the appearance of healthy granulation tissue, epithelialization, pain, discharge, and smell. RESULTS: Before treatment, the wound area was 8 cm × 5 cm × 4 mm, with 0% epithelization, purulent discharge, pain, dark skin, and foul smell. On the 50th day, the ulcer size had decreased to 2 cm × 1 cm × 0.5 mm, epithelization increased from 0 to 80 %, and granulation increased from 20 to 80 %. Discharge and smell were reduced from severe to absent, and pain decreased from 8 to 1 out of 10 on a visual analog scale. CONCLUSION: Our case study demonstrated the efficacy of leech therapy as a safe, non-invasive therapeutic approach, creating opportunities for its use in treating venous ulcers. Further research is warranted to determine the efficacy and effectiveness of leech therapy. KEYWORDS: Venous ulcer, Leech Therapy, Ta'līq al- 'Alaq, Unani Medicine, Case report.
Effectiveness of Yoga-A Mind-Body Intervention for Pain and Stress Associated with Primary Dysmenorrhea: A Narrative Review.
Shetty DP, Patil NJ, Shyamala G … +3 more , Belle VS, Annapoorna K, Ghosh M
Adv Mind Body Med · 2025 Fall · PMID 40700532
ABSTRACT: Primary dysmenorrhea, characterized by menstrual pain and associated stress, significantly impacts the quality of life for many women. Yoga, as a holistic mind-body practice, has emerged as a promising compleme...
ABSTRACT: Primary dysmenorrhea, characterized by menstrual pain and associated stress, significantly impacts the quality of life for many women. Yoga, as a holistic mind-body practice, has emerged as a promising complementary approach for managing primary dysmenorrhea. This review consolidates evidence-based insights from key studies, highlighting the therapeutic potential of yoga in alleviating both physical and psychological symptoms of primary dysmenorrhea. It explores the three core components of yoga-Physical Postures (Asanas), Meditation (Dhyana), and Breathing Exercises (Pranayama)-and examines their positive effects at cellular and systemic levels. Unlike previous studies that primarily focused on the general benefits of yoga modules, this narrative review uniquely emphasizes the underlying mechanisms through which yoga practices reduce pain and relieve stress. The evidence indicates that regular yoga practices can reduce pain, improve mood, and enhance overall well-being in affected women. While existing studies present some limitations, they collectively support the role of yoga as an effective non-pharmacological intervention for primary dysmenorrhea. Further research is needed to establish the optimal duration, frequency, and specific yoga practices required for maximum therapeutic benefits. KEYWORDS: Asanas, Menstrual pain, Mind-body intervention, Pranayama, Primary dysmenorrhea, Yoga, Narrative review.
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