The study included 335 males who were exposed to occupational hazards over 5 years to the moment of cerebrovascular stroke. The authors analysed structure of clinical forms of cerebrovascular stroke, found a concept of v...The study included 335 males who were exposed to occupational hazards over 5 years to the moment of cerebrovascular stroke. The authors analysed structure of clinical forms of cerebrovascular stroke, found a concept of various age groups distribution in dependence on occupational factor type, established a frequency of cardiovascular risk factors distribution among males in dependence on occupational hazards, revealed foiecasting value of intensity ranks in cerebrovascular stroke patients at the disease presentation.
Yakimova NL, Sosedova LM, Vokina VA
… +2 more, Titov EA, Novikov MA
Med Tr Prom Ekol
· 2017 · PMID 30351851
In lead intoxication model, with hyperglycenia state, atherogenicity coefficient reached 1,45 (1,35-1,85), if compared to 1,30 (0,85-1,40) in white rats exposed to lead. Heart rate reached 421,00 (411,00-468,00) per minu...In lead intoxication model, with hyperglycenia state, atherogenicity coefficient reached 1,45 (1,35-1,85), if compared to 1,30 (0,85-1,40) in white rats exposed to lead. Heart rate reached 421,00 (411,00-468,00) per minute vs, 385,50 (359,00-399,50) per minute in animals died with lead intoxication, shorter median interval between QRS-complexes up to 143,00 (128,00-146,00) ms vs, 160,00 (150,50-169,00) ms was seen in animals exposed to lead.
The article is aimed to systematically review evidence-based data published in foreign literature on influence of level and characteristics of occupational noise on hearing loss. Search of the literature was based on key...The article is aimed to systematically review evidence-based data published in foreign literature on influence of level and characteristics of occupational noise on hearing loss. Search of the literature was based on key words "occupational noise exposure, permissible exposure limit, dose-response relationship, acceptable noise level, noise-induced hearing loss" The authors studied 349 publications, 7 out of which were included into the present systematic review. Findings are that developed countries demonstrate a tendency to decreased prevalence of hearing loss among workers exposed to noise. Occupational groups with increased risk include workers of mining, machinery, light industries and agriculture. Lower occupational risk or no risk of hearing loss is seen in education, transport workers, musicians and other groups. Occupational noise level of 80 dB is a theoretically minimal exposure level resulting in no increase in hearing loss risk. Following normal noise level at 85 dB could decrease prevalence of hearing loss due to noise.
Deep clinical instrumental examination covered workers of National research center <<Kurchatovsky Institute>>, who are exposed to complex of occupational hazards, to diagnose endocrine disease and assess complications ri...Deep clinical instrumental examination covered workers of National research center <<Kurchatovsky Institute>>, who are exposed to complex of occupational hazards, to diagnose endocrine disease and assess complications risk. Suggestions are to proceed with specified timely treatment and prophylaxis for optimal health of the examinees and possible complications prevention.
Klimkina KV, Novikova AV, Lapko IV
… +1 more, Bogatyreva IA
Med Tr Prom Ekol
· 2017 · PMID 30351848
Comparative analysis covered emotional personality disorders in vibration disease patients'in dependence on presence and intensity of androgen deficiency. Parameters of depression, personal and actual anxiety in vibratio...Comparative analysis covered emotional personality disorders in vibration disease patients'in dependence on presence and intensity of androgen deficiency. Parameters of depression, personal and actual anxiety in vibration disease patients are reliably higher in those with marked clinical and laboratory signs of androgen deficiency.
Preobrazhenskaya EA, Sukhova AV, Il'nitskaya AV
… +1 more, Zor'kina LA
Med Tr Prom Ekol
· 2017 · PMID 30351847
Using a complex of contemporary audiologic methods (high-frequency audiometry, acoustic reflexometry registration of otoacoustic emission at aberration product frequency), examination covered 483 underground miners expos...Using a complex of contemporary audiologic methods (high-frequency audiometry, acoustic reflexometry registration of otoacoustic emission at aberration product frequency), examination covered 483 underground miners exposed to intensive noise. The most sensitive methods to diagnose early changes in fuctional state of hearing analyser at stage when tonal audiometry fails to determine hearing thresholds are otoacoustic emission at aberration product frequency (sensitivity 75%) and hearing study in extended frequency rating (sensitivity 65%). The authors specified a complex of informative parameters for early diagnosis and group risk identification of occupational deafness. Advisability is to include contemporary electroacoustic and neurophysiologic audiologic methods into routine periodic medical examinations.
Hygienic evaluation covered work conditions and health state of medical personnel working with magnetic resonance tomographs. Work conditions of the medical personnel are characterized by a complex of hazards: constant m...Hygienic evaluation covered work conditions and health state of medical personnel working with magnetic resonance tomographs. Work conditions of the medical personnel are characterized by a complex of hazards: constant magnetic field, increased intensity and hardiness of work, inadequate natural illumination, noise. The most unfavorable conditions are seen in diagnostic room during patients' preparation to the examination, where magnetic induction levels considerably exceed maximally allowable levels. The authors revealed reliable differences in functional parameters indicative of lower adaptational body resources in work with magnetic resonance tomographs. Suggestions are preventive measures to provide hygienic safety for medical personnel.
Lapko IV, Kir'yakov VA, Pavlovskaya NA
… +2 more, Antoshina LI, Oshkoderov OA
Med Tr Prom Ekol
· 2017 · PMID 30351845
The authors revealed influence of occupational vibration on development of resistance to insulin and of II type diabetes mellitus in miners. With that, increased serum insulin level was diagnosed in the workers. Occurren...The authors revealed influence of occupational vibration on development of resistance to insulin and of II type diabetes mellitus in miners. With that, increased serum insulin level was diagnosed in the workers. Occurrence of patients with. increased insulin level reaches 70% in vibration disease. The most intensively changed indexes are CARO and HOMA-IR, that identify early latent changes in resistance to insulin. Vibration appeared to influence significantly on II type diabetes mellitus development. Prevalence of II type diabetes mellitus among vibration disease patients is 5 times higher than that in general population of Russian Federation.
The article presents results ofhygienic studies on work conditions in using imidacloprid-based pesticides in agriculture. Analysis covered imidacloprid levels in air of workplace, on skin and in urine of workers.The article presents results ofhygienic studies on work conditions in using imidacloprid-based pesticides in agriculture. Analysis covered imidacloprid levels in air of workplace, on skin and in urine of workers.
Fedina IN, Serebrvakov PV, Smolvakova IV
… +1 more, Melent'ev AV
Med Tr Prom Ekol
· 2017 · PMID 30351843
The article covers studies on determining priority risk factors for health of female workers of heat-and-power engineering enterprise, risk groups revealed, suggestions for medical examinations with investigations in ear...The article covers studies on determining priority risk factors for health of female workers of heat-and-power engineering enterprise, risk groups revealed, suggestions for medical examinations with investigations in early diagnosis of cardiovascular system dysadaptation.
Sukhova AV, Kir'yakov VA, Yatsyna IV
… +2 more, Preobrazhenskaya EA, Zheglova AV
Med Tr Prom Ekol
· 2017 · PMID 30351842
Examination of 648 workers in ore mining and processing enterprises demonstrated role of psycho-social factors in diagnosis and development of occupationally conditioned dorsopathies, revealed the most important occupati...Examination of 648 workers in ore mining and processing enterprises demonstrated role of psycho-social factors in diagnosis and development of occupationally conditioned dorsopathies, revealed the most important occupational and non-occupational factors influencing dorsopathies development. Findings also are clinical and psychologic criteria of health disorders in workers with occupationally conditioned dorsopathies. The authors suggested scientifically justified approaches to preventions of dorsopathies and to workers' health preservation.
The authors presented results of hygienic evaluation of various techonologies connected with use of fipronil-based insecticides. Findings are allowable risk of fipronil exposure in workers, if technologic regulations and...The authors presented results of hygienic evaluation of various techonologies connected with use of fipronil-based insecticides. Findings are allowable risk of fipronil exposure in workers, if technologic regulations and safety rules met. Exceeded allowable risk in some technologies is due to technologic process features, outdated equipment and poor efficiency of individual protective means - that requires management decisions.
Comparative evaluation of clinical, neurophysiologic and laboratory data changes in 154 workers exposed to vibration in mining industry helped to identify the most informative criteria of vibration disease diagnosis. Sci...Comparative evaluation of clinical, neurophysiologic and laboratory data changes in 154 workers exposed to vibration in mining industry helped to identify the most informative criteria of vibration disease diagnosis. Scientifically justified use of neurospecific parameters - S100B protein and neurospecific enolase - was aimed to evaluate vibration disease severity.
For biomonitoring of exposure in workers with insectocaricides, the authors created a method of multi-component assessment oflowlevels of neonicotinomides in workers' urine, based on last generation tandem liquid mass-sp...For biomonitoring of exposure in workers with insectocaricides, the authors created a method of multi-component assessment oflowlevels of neonicotinomides in workers' urine, based on last generation tandem liquid mass-spectrometry (triple quadrupole) with ionization source - electrostatic dispersion (positive ionization) in dynamic multi-reaction monitoring with two transitions of parent ions (for quantitative assessment and ionic ratio confirmation). After the work, the operators gave urine samples (about 100 ml in average) that were frozen and kept under -20⁰C before analysis. Samples were defrozen before analysis, and each urine portion of 5 ml was diluted by equal volume of 0,1% formic acid. To extract substances out of the samples, solid-phase extraction (cartridges based on octadecylsilane) was applied, elution was performed with 1 ml of methanol. Lower limit of the substances detection in urine - 0,02-0,05 ng/ml, lower limit of the quantitative assessment - 0,1-0,2 ng/ml. The method was tested on monitoring of the workers' exposure to preparations based on imidaclopride and clotianidine in natural conditions of pesticides use in agriculture with various processing technologies. midacloprid was identified in urine of 3 professional operators after wheat and oat seeds treatment and after subsequent seeding at lower limit of detection (0,02 ng/ml), lower limit of quantitative assessment (0,1 ng/ ml) and 0,34 ng/ml.
Miryutoval NF, Zaitsev AA, Panacheva LA
… +1 more, Zaikina EA
Med Tr Prom Ekol
· 2017 · PMID 30351797
Important role in treatment and prophylaxis for vibration disease due to local vibration is played by physical factors. If high frequency components prevalent in occupational vibration, treatment with electric therapy, l...Important role in treatment and prophylaxis for vibration disease due to local vibration is played by physical factors. If high frequency components prevalent in occupational vibration, treatment with electric therapy, laser, magnetic fields, lymphatic drainage, hydrotherapy provides influence on leading chains of systemic microangiopathies pathogenesis - dysbalance of regulation influences by vegetative nervous system, vasoconstriction and intravascular changes, vascular permeability and microcirculation disorders. If low frequency coomponents prevalent in occupational vibration, treatment of polyneuropathies and locomotory disorders incorporates trophic processes activation: transcranial electroanalgesia, surface application of mineral waters, manual and subwater massage, ozone therapy, local spark discharges, peloids. Complex use of physical methods also increases human adaptational resources.
Examination covered 245 individuals and included characteristics of endocrine state of pulp and paper plant workers over 2011-2012, in comparison with data from 1990, as well as comparison with reference groups of male w...Examination covered 245 individuals and included characteristics of endocrine state of pulp and paper plant workers over 2011-2012, in comparison with data from 1990, as well as comparison with reference groups of male workers with no contact with chemical'industry in Arkhangelsk. Findings are both in main and reference groups general decrease in levels of cortisol, thyroxin;progesterone, testosterone, insulin, somatotropin and increased serum level of estradiol. With that, inside both groups, reliable tendencies to increased levels of cortisol, thyroxin, insulin, SSH and lower concentration of progesterone in the pulp and paper plant workers vs. the reference group members. Positive tendency was absence of abnormal concentrations of insulin, SSH and lower frequency of high cortisol levels in the pulp and paper plant workers nowadays.
Shpagina LA, Kotova OS, Shpagin IS
… +1 more, Gerasimenko ON
Med Tr Prom Ekol
· 2017 · PMID 30351795
Prospective cohort observational study covered phenotypic features of COLD formed under influence of various occupational etiologic factors vs. COLD caused by tobacco smoking. The study included totally 170 COLD patients...Prospective cohort observational study covered phenotypic features of COLD formed under influence of various occupational etiologic factors vs. COLD caused by tobacco smoking. The study included totally 170 COLD patients (2011 criteria of COLD). In accordance with exogenous etiologic factor, the authors selected examinees in 3 strata simultaneously: COLD due to toxico-chemical aerosols (n = 42), COLD due to inorganic dust (n = 55), COLD due to tobacco smoking (n = 73). Evaluation covered influence of ecologic and industrial conditions on main mainfestations of the disease. Statistic analysis: comparison of quantitative variables - Kruskal-WaRIisANOVA, quantitative variables - criteria c(2), influence of independent variable on the dependent one - single-factor and multi-factor regression, p = 0,05. For COLD due to toxico-chemical aerosol, characteristics are rare but severe exacerbations .(total amount is 366/427 person-years, severe ones - 312/427 person-years), severe dyspnea (mMRC 2,5 ± 0,12 points), minimal decrease of FEVI (65,7% ? 3,21%) and minimal speed of bronchial obstruction progress (decrease of FEV1 by 0,08 ml ± 0,006 ml per year), emphysema, pulmonary hypertension, low serum level of VEGFA. For COLD due to dust, characteristics were bronchial hyperreactivity (in 45% of patients), cough, rare severe exacerbations (total exacerbations 825/537 person- years, severe ones - 227/537 person-years), lower dyspnea intensity (mMRC 1,9 ± 0,13 points), concomitant interstitial fibrosis, "average" level of VEGFA.
The study covered lipid content of RBC membranes in divers exposed to extreme hyperbaric factors at work. Findings are that prophylactic intake of biologically active additive nutrient "Kalifen" made of viburnum berries...The study covered lipid content of RBC membranes in divers exposed to extreme hyperbaric factors at work. Findings are that prophylactic intake of biologically active additive nutrient "Kalifen" made of viburnum berries preserved physiologic characteristics of RBC and recovery of lipid components in their membranes.
The authors present results of X-ray examination of miners working incleaning mine face, subjected to complex of occupational hazards (dust aerosols, physical overexertion) among which local and combined occupational vib...The authors present results of X-ray examination of miners working incleaning mine face, subjected to complex of occupational hazards (dust aerosols, physical overexertion) among which local and combined occupational vibration could be the most important from the viewpoint of possible occupational osteopathy. Examinees were males: 60 ones with suspected vibration disease,. 35 ones with diagnosed vibration disease (vegetative sensory polyneuropathy) stage 1 and 30 ones in reference group matched by age and length of service. For osteoporosis diagnosis (according to mineralization level in distal forearms), the authors evaluated possibilities of digital osteodensitometry standard in occupational therapy with digital low-dose X-ray devices.
Khodzhiev M, Yushkova OI, Shardakova EF
… +1 more, Kapustina AV
Med Tr Prom Ekol
· 2017 · PMID 30351792
The article presents results of physiologic studies of nine occupational groups of migrants from south republics of Middle Asia to Moscow region of Russian Federation. The authors revealed features of cardiac rhythm regu...The article presents results of physiologic studies of nine occupational groups of migrants from south republics of Middle Asia to Moscow region of Russian Federation. The authors revealed features of cardiac rhythm regulation variability in the migrants in accordance with physical exertion value and psychoemotional characters of work. Optimization of the adaptation processes should get along with organization of rational work and rest schedule, healthy lifestyle formation, better medical service to the migrants.