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Women Health [JOURNAL]

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Assessing menopause symptoms in women with traumatic brain injury: the development and initial testing of a new scale.

Kalpakjian CZ, Hanks R, Quint EH … +6 more , Millis S, Sander AM, Lequerica AH, Bushnik T, Brunner R, Rapport L

Women Health · 2024 Jan · PMID 38097958 · Publisher ↗

With greater survival rates after catastrophic injury, more women with traumatic brain injury (TBI) are living longer than ever. However, knowledge about this transition in these women is largely unexamined and there are... With greater survival rates after catastrophic injury, more women with traumatic brain injury (TBI) are living longer than ever. However, knowledge about this transition in these women is largely unexamined and there are no scales that have been developed to assess the experience of symptoms. To address this gap, we developed and tested a new scale of menopause symptoms in midlife women with TBI. We selected candidate items from two existing measures based on feedback from focus group discussions with seven women with TBI. Twenty candidate items were tested in cognitive interviews with six women with TBI/1 non-TBI. Then, these were field tested with 221 participants (TBI,  = 68; non-TBI,  = 153) recruited from registries. Rasch analysis and convergent validity testing were used to evaluate the new scale. Results of the Rasch analysis indicate that overall, the scale fits well the Rasch model with evidence for unidimensionality. Differential item functioning indicated that the scale performed equally well for women with and without TBI and distinguished pre- and post-menopausal states. Convergent validity was found in the expected directions. These findings support further development of the new scale to understand the experience of menopause symptoms among women with TBI.

Determination of risky sexual behaviors and associated factors of Turkish young women.

Bilge C, Kaydirak M, Saçan U … +1 more , Demir F

Women Health · 2024 Jan · PMID 38014446 · Publisher ↗

Risky sexual behaviors of young women cause significant reproductive health problems. Therefore, it is vital to evaluate the sexual attitude and behavior characteristics of young women, their changes over the years, and... Risky sexual behaviors of young women cause significant reproductive health problems. Therefore, it is vital to evaluate the sexual attitude and behavior characteristics of young women, their changes over the years, and the effects of information sources such as family, media, and friends, which play an effective role in bringing about changes in sexual behavior of young women. This study was planned to evaluate young women's premarital sexual behaviors and related factors in Turkiye between 01.11.2021 and 01.05.2022. It is designed as a descriptive correlation study conducted with 1.430 young women studying at universities in 30 metropolitan cities in Turkiye. The study data were collected using the "Participant Information Form" and the "Premarital Risky Sexual Behavior Assessment Scale for Young Women." This study showed that parents' educational status and geographical region was related to the young women's mean score and the subdimension score of the Premarital Sexual Behavior Assessment Scale for Young Women (PSAS-YW) ( < .001). Furthermore, young women's top source of information about sexuality was internet media (80 percent,  = 1144), and the least source was their fathers (2.9 percent,  = 41). There is a relationship between where young women spend most of their lives, the geographical region where their families live, and the risk of sexual behavior. The study observed that the geographical region where young women's parents live was effective in risky sexual behavior. While less risky sexual behavior was observed, primarily in the country's east, this rate increased in the western parts. Furthermore, while it was determined that young people mainly acquire sexual information through the media-internet or friends, it was observed that the participants in this group had the highest rate of risky sexual behavior. The age variable explained only 2 percent of the change in risky sexual behavior, and there was a linear increase between the mother's education level and the risky sexual behavior score of young women.

Investigation of crocin's protective effect on cyclophosphamide-induced hypothalamic-pituitary-gonadal axis defects in adult female rats.

Shams E, Zohrabi D, Omrani O … +3 more , Zarezade V, Yazdanpanahi N, Sanati MH

Women Health · 2024 Jan · PMID 38014433 · Publisher ↗

Cyclophosphamide is a drug used in chemotherapy. However, it has side effects, including changes in reproductive system functioning. Some herbal compounds can reduce the harmful effects of cyclophosphamide. This study ai... Cyclophosphamide is a drug used in chemotherapy. However, it has side effects, including changes in reproductive system functioning. Some herbal compounds can reduce the harmful effects of cyclophosphamide. This study aims to investigate the protective role of crocin against changes caused by Cyclophosphamide in ovarian tissue through changes in the expression of genes involved in the hypothalamic-pituitary-gonadal axis. This experimental study was performed on 24 adult female Wistar rats. Mice were divided into four groups (normal saline, 30 mg/kg cyclophosphamide, 100 mg/kg crocin and 30 mg/kg cyclophosphamide, and 200 mg/kg crocin and 30 mg/kg cyclophosphamide). At the end of the treatment period, the hypothalamus and ovaries were also removed to evaluate genes expression using real-time PCR and histological changes in the ovaries. Data were analyzed by SPSS statistical software. The expression of genes, number of follicles, and follicle diameter significantly decreased in the cyclophosphamide-treated groups compared with the control group. In the crocin and cyclophosphamide-treated groups, drug-induced reproductive complications were mitigated. The current findings indicate that by increasing the expression of genes , , and , crocin could modulate the harmful effects of cyclophosphamide.

Menopausal symptoms, exercise practices, and advice received in active women: a multi-country survey of strava app users.

Carter E, Bruinvels G, Timmins K … +2 more , Pedlar C, Martin D

Women Health · 2024 Jan · PMID 37996389 · Publisher ↗

The study aimed to identify the prevalence of symptoms, changes in exercise levels, and exercise advice received during the menopausal transition in a large multi-country sample. Using total population sampling, 2.5 perc... The study aimed to identify the prevalence of symptoms, changes in exercise levels, and exercise advice received during the menopausal transition in a large multi-country sample. Using total population sampling, 2.5 percent of female Strava app users ( = 970) from 7 countries completed an online survey between 14 February 2019 and 11 March 2019. The survey discussed menopause status (perimenopausal or postmenopausal), menopausal symptoms, changes to exercise behaviors, and advice received concerning exercise during menopause. Frequencies, chi-square statistics, and linear regressions were used to analyze data. The most commonly reported menopausal symptoms were sexual (18-83 percent) and cognitive/psychological (77-78 percent). 41 percent of women reported no change in exercise behavior since menopause began (46 percent increased and 11 percent decreased behaviors). The majority (88 percent) of women did not receive advice regarding exercise during menopause. Women who received advice were more likely to report an increase in their exercise than those not receiving advice (60 percent vs 46 percent; X (df 2,  = 927) = 7.1,  = .03). Exercise behaviors increased the longer it had been since the menopausal onset (X (df 8,  = 937) = 77.42,  < .001). The results suggested high menopausal symptom prevalence in active women and a general lack of exercise advice. More women reported higher symptom prevalence and an increase in exercise participation, the longer it had been since menopause onset. Future research should determine whether these increased exercise behaviors are being used as a coping mechanism.

Estrogen hormone therapy and postmenopausal osteoporosis: does it really take two to tango?

Silva BC, Hipólito Rodrigues MA

Women Health · 2023 Nov · PMID 37975286 · Publisher ↗

Abstract loading — click title to view on PubMed.

Uterine scar evaluation: a hard nut to crack.

Nogueira Neto J, Ayroza Ribeiro HSA, Galvão Ribeiro PAA

Women Health · 2023 Nov · PMID 37975285 · Publisher ↗

Abstract loading — click title to view on PubMed.

Is decision-making based on the internet during pregnancy a predictive factor for vaccine hesitancy in pregnant women during the pandemic?

Uludağ E, Serçekuş P, Yıldırım Gökşen DF … +2 more , Alataş SE, Özkan S

Women Health · 2024 Jan · PMID 37933189 · Publisher ↗

Pregnant women frequently use the Internet to get information, and the information they receive is effective in their decision-making. It is known that pregnant women get information about COVID-19 vaccines from the Inte... Pregnant women frequently use the Internet to get information, and the information they receive is effective in their decision-making. It is known that pregnant women get information about COVID-19 vaccines from the Internet. This study aims to determine whether decision-making based on Internet sources during pregnancy is a predictive factor for vaccine hesitancy in pregnant women during the pandemic. A descriptive, cross-sectional research design was used. The data were collected by using an online survey instrument. There was a positive, moderate, and significant relationship between the self-efficacy perception sub-dimension of the internet decision-making during pregnancy scale and the risk sub-dimension of the vaccine hesitancy in pandemics scale (r: .584,  < .05) and between the self-control sub-dimension of the internet decision-making during pregnancy scale and the risk sub-dimension of the vaccine hesitancy in pandemics scale (r: .546,  < .05). The perception of self-control (β: .291) affected the lack of confidence, and the perception of self-efficacy (β: .481) affected the risk perception more than other variables. There was a relationship between internet decision-making and COVID-19 vaccine hesitancy in pregnant women. Health professionals, information specialists, and librarians should orient people to reliable sources about vaccines.

The effects of women's insight levels on breast cancer prevention behaviors: a cross-sectional study.

Bayir B, Ünal E, Küçükköseler AD

Women Health · 2023 Nov · PMID 37933087 · Publisher ↗

The aim of this study is to determine the effect of women's insight levels on their breast cancer prevention behaviors in primary health care services. A systematic sampling method was used to select a sample of 393 wome... The aim of this study is to determine the effect of women's insight levels on their breast cancer prevention behaviors in primary health care services. A systematic sampling method was used to select a sample of 393 women in a province in Turkey. Socio-demographic Characteristics Form, Insight Scale and Scale for Determining Factors Affecting Women's Breast Cancer Prevention Behaviour were used as data collection tools. Data were collected face-to-face and then analyzed statistically using Student's t-test, one-way analysis of variance, Tukey HSD, Spearman correlation test and multiple regression analysis. The results showed that those who felt "healthy" had significantly higher mean breast cancer prevention behavior ( < .05). It was determined that there was a weak positive correlation between the level of insight and breast cancer prevention behaviors, and the increase in the level of insight had a significant positive effect of 0.37 ± 0.051 points on breast cancer prevention behaviors. It was found that there was a significant negative effect on prevention behaviors with 1.66 ± 0.796 points in those with a high education level and 1.58 ± 0.505 points in those with suspected disease. In conclusion, in this study, it was determined that insight level, education level, and awareness of early diagnosis affected the prevention behaviors of breast cancer.

Do postpartum insomnia, fatigue and depression affect the maternal role of primiparous women?

Ozdemir J, Ozcan S

Women Health · 2023 Nov · PMID 37919971 · Publisher ↗

Many factors negatively affect the motherhood role. Fatigue, insomnia and depression, which are among these factors, have not been investigated together in any study. Therefore, we carried out this study to determine the... Many factors negatively affect the motherhood role. Fatigue, insomnia and depression, which are among these factors, have not been investigated together in any study. Therefore, we carried out this study to determine the effect of insomnia, fatigue and depressive symptoms on the motherhood role in primiparous mothers. In this descriptive and cross-sectional study, we included 153 women who met the inclusion criteria using the simple, random sampling method. To determine the independent variables affecting the motherhood role, we used the backward regression model. In this study, we determined that the women's spending more energy while they performed the activities of daily living in the postpartum period, their suffering from insomnia due to baby care and their depressive symptoms affected their motherhood role by 32.6 percent. We also determined that there was a moderately significant relationship between insomnia, fatigue and depressive symptoms in the postpartum period. In particular, because depressive symptoms are the variable most related with the motherhood role ( = -0.520;  < .001), women should be followed-up regularly in the postpartum period from this aspect. It is also important to deal with insomnia in the early postpartum period, because it is a common problem in most women after childbirth.

The impact of relationship status on IVF patients' quality of life.

Bokek-Cohen Y

Women Health · 2024 Jan · PMID 37919948 · Publisher ↗

Infertility treatments are emotionally taxing and include invasive and time-consuming procedures over extended periods of time. In light of the growing numbers of single mothers by choice, the objective of this study was... Infertility treatments are emotionally taxing and include invasive and time-consuming procedures over extended periods of time. In light of the growing numbers of single mothers by choice, the objective of this study was to apply the Conservation of Resources Theory in the context of infertility care and examine whether relationship status constitutes a psychological resource that buffers the decline in quality of life during IVF treatments. We used the FertiQol questionnaire to compare the quality of life of IVF patients between 422 patients who are involved in a couple relationship ("attached") and 117 patients who are not ("unattached"). Results show that the total FertiQol was significantly higher among the attached participants; the Core FertiQol and the Treatment FertiQol were rated higher by the "attached." No significant differences were found between the attached and unattached for the Emotional and Social subscales. "unattached" participants report significantly lower levels of quality of life in the "mind-body" and "treatment tolerability" subscales than the "attached" participants. It is concluded that being involved in a long-term couple relationship is to be seen as a resource that buffers the decline in quality of life of infertile women undergoing IVF treatments.

Evaluation of , and gene polymorphisms as risk factor for endometrial polyp.

Tcherniakovsky M, de Oliveira E, Martinelli Sonnenfeld M … +7 more , Arcoverde Cavalcanti Meniconi MM, Franco de Oliveira M, Tcherniakovsky I, Moscovitz T, Wajman M, Camargo Mariano da Silva R, Fernandes CE

Women Health · 2023 Nov · PMID 37908103 · Publisher ↗

The aim of this study is to evaluate , and gene polymorphisms and occurrence of endometrial polyps. In addition, we intended to evaluate the clinical and epidemiological features of patients with and without the presenc... The aim of this study is to evaluate , and gene polymorphisms and occurrence of endometrial polyps. In addition, we intended to evaluate the clinical and epidemiological features of patients with and without the presence of the disease, characterizing the possible risk factors. A cross-sectional study was performed, with a total of 309 women, including 236 in the group of women with endometrial polyp confirmed by hysteroscopy and anatomical pathological examination and 73 in the group of people with diagnostic hysteroscopy without abnormal findings from the macroscopic point of view. Polymorphisms of four genes were studied: (rs4680), (rs5031015), (rs1056836), and (rs2234693). Polymorphism genotyping was determined using real-time polymerase chain reaction. Considering the results, no differences were identified between the two groups with respect to age, body mass index, diabetes, dyslipidemia, or smoking. The group of women without endometrial polyps showed higher use of hormone therapy than the other group (16.4 percent versus 3.8 percent,  < .001). The , and genes exhibited no significant difference for the occurrence of endometrial polyp between the two groups. The research concluded that no correlation was identified between the genetic polymorphisms evaluated and the presence of endometrial polyps.

Why women continue to smoke during pregnancy: a qualitative study among smoking pregnant women.

Keten Edis E, Keten M

Women Health · 2023 Nov · PMID 37905544 · Publisher ↗

Smoking during pregnancy is a serious public health concern due to its adverse consequences on fetal development and pregnant women's health. For the success of smoking cessation interventions, it is essential to determi... Smoking during pregnancy is a serious public health concern due to its adverse consequences on fetal development and pregnant women's health. For the success of smoking cessation interventions, it is essential to determine why pregnant women continue smoking. The objective of this study is to determine the beliefs, attitudes, and barriers to quitting smoking during pregnancy. We adopted a qualitative research design. The participants consisted of 22 pregnant women who smoke, selected by purposive sampling. We collected data through semi-structured interviews and analyzed it using thematic analysis. We identified six themes namely "Reasons for starting to smoke: family and social environment," "Intention to quit smoking and related factors," "Smoking and emotional well-being," "Smoking and stressful life experiences," "Protective thoughts: reducing smoking to safeguard their babies," and "Belief in a healthy pregnancy and inadequate risk perception." Women expressed the desire to protect their fetus from the harm of smoking. However, they continued to smoke due to a lack of knowledge, inadequate risk perception, psychological difficulties, and lack of motivation. Health professionals should be aware of the difficulties experienced by pregnant women who smoke and should support them in quitting smoking.

Sexual victimization by current partner is negatively associated with women's sexual satisfaction.

Osman SL

Women Health · 2023 Nov · PMID 37876326 · Publisher ↗

Lower sexual satisfaction with one's current partner (SSCP) has been associated with having a history of sexual victimization experience (SVE). However, whether or not this SVE involved the current partner as the perpetr... Lower sexual satisfaction with one's current partner (SSCP) has been associated with having a history of sexual victimization experience (SVE). However, whether or not this SVE involved the current partner as the perpetrator has been unclear. This study aimed to address this gap in the sexual health literature by examining women's SSCP based on SVE with that current partner (yes; no) and/or a different perpetrator (yes; no). A convenience sample of undergraduate women with an exclusive current partner ( = 412; 99 percent unmarried) at a U.S. public university anonymously responded via paper-and-pencil to the Global Measure of Sexual Satisfaction and the Sexual Experiences Survey-Short Form Victimization between 2012-2016. A 2 × 2 ANOVA revealed that current-partner SVE was associated with lower SSCP ( (1, 410) = 7.38,  = .007,  = .018), but other-perpetrator SVE was not. SVE may predict lower SSCP when victimized by that partner, as that partner may be associated with the negative victimization experience. Although preliminary, findings highlight the importance of considering how partner-related health factors (e.g. SSCP) may be differentially associated with SVE based on whether or not the victim's current partner was the perpetrator.

Spouses' coping with stress during the COVID-19 pandemic: is there a difference between male and female attitudes?

Keskin G, Gümüşsoy S, Taşdemir Yiğitoğlu G

Women Health · 2023 Nov · PMID 37876322 · Publisher ↗

This descriptive study was conducted to determine the stress-coping status of spouses and the difference between male and female attitudes during the pandemic period. We collected data with the Personal Information Form... This descriptive study was conducted to determine the stress-coping status of spouses and the difference between male and female attitudes during the pandemic period. We collected data with the Personal Information Form and the Scale for Coping with Family Stressors from 533 participants. The mean age of women and men was 36.04 ± 10.04 and 37.13 ± 11.56, respectively. A significant difference in verbalizing with others, work - family segmentation, cognitive restructuring, changing behaviors, emotional disclosure, exercise, and spending more time with family was found between women and men ( < .05). A significant difference was also observed in coping mechanisms with family stressors between women and men, and thus, gender affects their coping attitudes. During crises such as pandemics, the community should be aware of the availability of mental health professionals, and spouses should also use effective coping methods with family stress at regular intervals.

An investigation of the relationship between the general vaccination attitudes of pregnant women and their attitudes toward the COVID-19 vaccine.

Mamuk R, Akgün M, Turan Miral M … +1 more , Göksu Ş

Women Health · 2023 Nov · PMID 37867344 · Publisher ↗

This study aimed to investigate the relationship between the attitudes of pregnant women toward general vaccines based on the Health Belief Model and their attitudes toward the COVID-19 vaccine. The study, which was desi... This study aimed to investigate the relationship between the attitudes of pregnant women toward general vaccines based on the Health Belief Model and their attitudes toward the COVID-19 vaccine. The study, which was designed as a descriptive, cross-sectional, and correlational study, was conducted with 348 pregnant women in three public hospitals in Northern Cyprus between June 24 and November 28, 2022. Data were collected using the "Participant Information Form," "Public Attitude Toward Vaccination Scale-Health Belief Model" (PAVS-HBM), and "Attitudes Toward the COVID-19 Vaccine" (ATV-COVID-19). The COVID-19 vaccination rate among pregnant women was quite high. Pregnant women have a high perception of sensitivity, importance, benefit, and health responsibility for routine vaccines and vaccination programs based on the HBM, and a low perception of barriers to vaccination. These results showed that pregnant women have a determined and positive attitude toward the acceptance of vaccines in general. On the other hand, the attitude of pregnant women toward the COVID-19 vaccine was moderately negative. Despite the reservations about the COVID-19 vaccine, a determined and positive attitude toward vaccines in general has increased acceptance of the COVID-19 vaccine.

Mediating role of relational aggression in the association between infertility stigma and marital relationship distress in infertile women.

Mikaeili N, Eyni S, Mousavi SE … +1 more , Ebadi M

Women Health · 2023 Oct · PMID 37822291 · Publisher ↗

Infertility is a multifaceted problem that can cause significant impairments with emotional, social, and psychological consequences, including problems in the marital relationship. This study aimed to mediate the role of... Infertility is a multifaceted problem that can cause significant impairments with emotional, social, and psychological consequences, including problems in the marital relationship. This study aimed to mediate the role of relational aggression in the association between infertility stigma and marital relationship distress in infertile women. The research method was descriptive and path analysis. The statistical population of the study consisted of all infertile women who were referred to infertility centers and obstetrics and gynecology medical centers in Tehran in 2021 (July to October), and due to lack of full access to them, 300 people were selected by available sampling method who participated in the research through an online questionnaire. Data were collected using the Marital Self-Reporting Questionnaire, Infertility Stigma, and Relational Aggression Questionnaire. Data analysis was performed using structural equation modeling. The results showed that the causal model of the relationship between infertility stigma, relational aggression, and marital relationship distress in infertile women was confirmed based on different fitting indices. Infertility stigma and associated aggression directly affect the marital turmoil of infertile women. On the other hand, infertility stigma indirectly affects infertile women's marital distress through relational aggression ( < .05). Therefore, the infertility stigma and relational aggression play an important role in marital distress in infertile women, and targeting these two components in psychological therapies can effectively reduce marital chaos.

Fertility preservation for women diagnosed with breast cancer: looking beyond the horizon.

Coutinho LM, Polisseni F

Women Health · 2023 Oct · PMID 37822290 · Publisher ↗

Abstract loading — click title to view on PubMed.

The effect of continuous intrapartum supportive care on maternal mental health: a randomized controlled trial.

Kahraman HG, Gökçe İsbir G

Women Health · 2023 Nov · PMID 37807722 · Publisher ↗

Supportive care during labor is the primary role of intrapartum nurses and midwives and provides comfort for women allowing them to have a positive experience. It is argued that supportive care during labor reduces fear... Supportive care during labor is the primary role of intrapartum nurses and midwives and provides comfort for women allowing them to have a positive experience. It is argued that supportive care during labor reduces fear and resultant side effects. However, evidence for different parameters of mental health is insufficient. The aim of this study was to evaluate the effect of continuous intrapartum supportive care on the fear of childbirth, perceived control and support at birth, birth trauma and maternal attachment. This is a randomized controlled study with an intervention group and a control group. The intervention group included 40 women receiving continuous intrapartum supportive care and the control group included 40 women receiving routine care. Thirty women in the intervention group and 29 women in the control group completed the study. No significant differences were detected between the two groups at baseline ( > .05). Continuous intrapartum supportive care significantly decreased fear of birth and birth trauma, and significantly increased perceived intrapartum control and support and postpartum maternal attachment ( < .01). Results from this evidence-based study suggest that continuous intrapartum supportive care could protect and maintain perinatal mental health.

The compounding effects of income loss and change in living arrangement on emerging adult women's mental health during COVID's onset.

Trub L, Stewart JL, Oberndorf M … +2 more , Parker V, Starks TJ

Women Health · 2023 Oct · PMID 37794625 · Publisher ↗

Research suggests that young adult women were among those more susceptible to mental health declines in the initial months of COVID-19. Unfortunately, longitudinal data examining mental health before and after the pandem... Research suggests that young adult women were among those more susceptible to mental health declines in the initial months of COVID-19. Unfortunately, longitudinal data examining mental health before and after the pandemic's onset are extremely limited. In a sample of 240 women ages 18-29 who were surveyed online first in November-December 2019 and then again between May and July 2020, this study aimed to examine how major life changes associated with the pandemic (i.e. loss of income, loss of employment, change in relationship status, and change in living arrangement) impacted mental health (i.e. depression, anxiety, stress). Multivariate regression analyses were conducted on three models predicting stress, anxiety, and depression from the four life changes, controlling for the effects of mental health before the COVID-19 pandemic. Results showed that a change in living arrangement was uniformly associated with increased mental health problems among women who also experienced a decrease in income. Likewise, loss of income was uniformly related to increased mental health problems among women who also experienced a change in living arrangement. In contrast, job loss was associated with a decrease in stress, and changes in relationship status were not associated with mental health outcomes. These findings highlight the potential for COVID-19 to produce co-occurring and synergistic stressors. Meanwhile, the impact of job loss on mental health may have been attenuated by enhanced unemployment benefits. Mental health interventions that aim to support young women as the pandemic abates should be tailored to address the impact of multiple psychosocial stressors.

Frequency of post-treatment disease after excisional procedure in stage IA1 squamous cervical carcinoma - a case series.

Azzi PA, Bastos Russomano F, de Andrade CV … +2 more , de Camargo MJ, Moskovics Jordão P

Women Health · 2023 Oct · PMID 37779317 · Publisher ↗

Early stages of cervical cancer in young women need conservative treatments. Electrosurgical therapies (LLETZ, LEEP, SWETZ, NETZ) have been recommended for these women. However, there are recommendations to perform a sec... Early stages of cervical cancer in young women need conservative treatments. Electrosurgical therapies (LLETZ, LEEP, SWETZ, NETZ) have been recommended for these women. However, there are recommendations to perform a second excision when the specimen margins are not free of disease. This can lead to some important complications. This article aims to verify the frequency of residual invasive or microinvasive disease after the excisional procedure in women with IA1CC. Data on women with IA1CC diagnosed between 1990 and 2022, were retrieved from medical records. Post-treatment disease was detected during a second surgical procedure or postoperative follow-up. Among the 69 included women, three (4.3 percent; CI95 percent 0-9.2) had residual microinvasive lesions, while none showed invasive disease during a second procedure or follow-up. Only the age of 37 years or more was significantly related to the presence of preinvasive or microinvasive residual lesions. Nearly 80 percent of the women who underwent a second procedure showed no residual lesions. The absence of invasive disease in a second procedure or during the follow-up of these women and the large proportion of women with no residual lesion questions the need for a new surgical procedure even when the surgical margins of the initial specimen are involved.
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