Women Health [JOURNAL]
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200 papers
Knowledge, attitudes and practices of contraceptive methods among students in public and private high schools in Cameroon.
Gnimpieba Kassep CA, Sarpkaya Güder D
Women Health · 2024 Mar · PMID 38356119 · Publisher ↗
The use of contraceptive methods is still a controversial subject in the societies of developing countries. This study aims to assess the knowledge, attitudes, and practices of contraceptive methods among students, aged...
The use of contraceptive methods is still a controversial subject in the societies of developing countries. This study aims to assess the knowledge, attitudes, and practices of contraceptive methods among students, aged 15 to 25 years, in public and private schools in the district of Bonaberi, Douala, Cameroon. This research was modeled on the pattern of descriptive study. The population in this study was composed of students ( = 1649) from the five public and private high schools of Bonaberi, Cameroon. The sample size of this study was 379 students. These data were collected in person by the researcher between 1 and 30, June 2022. The data collection tools are the student information form, the Knowledge and Practices of Contraceptive Methods Questionnaire, and the Contraceptive Attitude Scale (CAS). The data of this study were analyzed using descriptive statistics tests, Kruskal-Wallis Test, Pearson Chi-Square, Kolmogorov-Smirnoff, Student's T-Test, Mann-Whitney Test, and the One-way ANOVA. It was found that almost half (45.91 percent) of students were 19-22 years old, 59.1 percent of them were male, and almost half (49.3 percent) of them were sexually active. Currently, the male condom is the most commonly used and known method of contraception among students. It was determined that students take an average of 3.406 points from the total score of CAS. This result indicated a positive attitude toward contraceptive methods. There were no statistically significant differences in contraceptive attitudes according to gender, religion, or sexual activity. There was a statistically significant difference in contraceptive attitudes according to marital status and age. It is recommended to provide family planning counseling services in these schools in order to increase the use of effective methods and provide students with a reliable source of information on contraceptive methods.
The effects of yoga and progressive muscle relaxation exercises on premenstrual syndrome: a randomized controlled trial.
Abic A, Dag-Canatan S, Er-Korucu A … +1 more , Aksoy-Can A
Women Health · 2024 Mar · PMID 38343144 · Publisher ↗
In this study, university students with premenstrual syndrome (PMS) were evaluated for their responses to the practices of yoga and progressive muscle relaxation (PMR) to combat PMS, and the depression, anxiety, and stre...
In this study, university students with premenstrual syndrome (PMS) were evaluated for their responses to the practices of yoga and progressive muscle relaxation (PMR) to combat PMS, and the depression, anxiety, and stress associated with it. A total of 68 students participated in a randomized controlled trial. They were divided into four parallel groups: a yoga intervention group ( = 17), a PMR intervention group ( = 17), a yoga and PMR intervention group ( = 17), and a control group ( = 17). Data were collected between April 2022 and June 2022, from students who practiced only yoga, who practiced only PMR, and who practiced both yoga and PMR. A Personal Information Form, the PMS Scale, and the Depression, Anxiety, and Stress Scale were used as measurement tools. The yoga and yoga + PMR groups had lower scores for the PMS Scale in the posttest than the other groups ( < .05). Depression, anxiety, and stress sub-dimension mean scores were lower in the yoga, PMR + yoga, and PMR groups compared to the control group ( < .05). The results suggest that yoga and PMR interventions are beneficial non-pharmacological treatments for PMS, depression, anxiety, and stress. The Effects of Yoga and Progressive Muscle Relaxation Exercises on Premenstrual Syndrome, NCT05396976, April 5, 2022.
The homeless period: a qualitative evidence synthesis.
Orsini GD, Tarabay J, Hardy-Johnson PL … +2 more , Barker SL, Greenway FT
Women Health · 2024 Mar · PMID 38343133 · Publisher ↗
Women experiencing homelessness are marginalized not only through their housing status but also through their access and ability to manage their menstrual health. Currently, there are no existing published reviews explor...
Women experiencing homelessness are marginalized not only through their housing status but also through their access and ability to manage their menstrual health. Currently, there are no existing published reviews exploring this topic. This study aimed to begin closing that gap, by systematically reviewing the literature examining women's experiences of menstruation whilst being homeless. In June 2020 (and updated in December 2022), we conducted comprehensive and systematic searches of four electronic databases: Medline, Web of Science, CINAHL, and PsychINFO, from which nine studies were found. The findings were thematically analyzed, using the enhancing transparency in reporting the synthesis of qualitative research tools (ENTREQ) guidelines. Three themes related to menstrual experiences were found: (1) challenges in the logistics of managing menstruation while homeless, (2) feelings of embarrassment, shame, and dignity linked to maintaining menstrual health, and (3) making do: how people experiencing homelessness manage challenges related to menstruation. We discuss barriers women face in getting necessary products and in accessing private, safe, and clean facilities to manage menstrual health. The study found that women living with homelessness often abandon other basic needs in favor of managing menstruation (i.e. using unsuitable materials, stealing, etc.), which furthers their risk. The findings highlight the need for future research to investigate the experiences of women who are menstruating while being homeless and what support they would find helpful. Results show that it is high time for commissioners and policy-makers to address the provision of menstrual resources as a basic human right.
"Social support and stressful life events: risk factors for antenatal depression in nulliparous and multiparous women".
Rodríguez-Muñoz MF, Marcos-Nájera R, Amezcua MD … +3 more , Soto-Balbuena C, Le HN, Al-Halabí S
Women Health · 2024 Mar · PMID 38297821 · Publisher ↗
Nulliparous (pregnant women who are giving birth for the first time) and multiparous (women who have multiple children) may have different concerns, which may be associated with risk of antenatal depression. This study a...
Nulliparous (pregnant women who are giving birth for the first time) and multiparous (women who have multiple children) may have different concerns, which may be associated with risk of antenatal depression. This study aims to examine the role of social support and stressful life events as risk factors for antenatal depression in nulliparous and multiparous women. The sample included 1,524 pregnant women recruited from an obstetrics setting at the end of the first trimester of pregnancy from two Spanish tertiary-care public hospitals. The sample completed the Patient Health Questionnaire (PHQ-9), and the "social support" and "stressful life events" subscales of the Postpartum Depression Predictor Inventory-Revised (PDPI-R). Nulliparous women reported a lower prevalence of depressive symptoms (15.6 percent) compared to multiparous mothers (20.1 percent). In both groups, marriage/partner problems (NP: β = 0.178, < .01 vs MP: β = 0.164, < .01) and a perceived lack of instrumental support from friends (NP: β = -0.154, < .01 vs MP: β = -0.154, < .01) were significant risk factors for antenatal depression. However, nulliparous women have more risk factors such as unemployment (β = 0.096, < .05), job change (β = 0.127, < .01), financial problems (β = 0.145, < .01) and lack of instrumental support from partner (β = -0187, < .01). For multiparous women, moving (β = 0.080, < .05) and lack of instrumental support from family (β = -0.151, < .01) were risk factors. These results suggest the critical need for screening and designing preventive interventions adapted and taking into consideration parity to provide more effective health care during pregnancy.
SOS reproductive healthcare: a call for action.
Carneiro MM
Women Health · 2024 Feb · PMID 38291884 · Publisher ↗
Abstract loading — click title to view on PubMed.
Factors associated with postpartum depression among high-risk women during the COVID-19 pandemic.
Farewell C, Tong S, Sehrt M … +2 more , Siegart J, Nicklas J
Women Health · 2024 Mar · PMID 38287691 · Publisher ↗
The purpose of this study was to investigate the impacts of the COVID-19 pandemic on multi-level factors associated with depression among a high-risk sample of postpartum women using longitudinal data collected at two ti...
The purpose of this study was to investigate the impacts of the COVID-19 pandemic on multi-level factors associated with depression among a high-risk sample of postpartum women using longitudinal data collected at two timepoints. High-risk postpartum participants in the United States were recruited to participate in a parent study focused on mitigating risk of cardiometabolic disease in postpartum women. Individuals completed a baseline survey which included the Edinburgh Postpartum Depression Scale (EPDS) at 6-weeks postpartum between 2017 through 2019. A modified survey with the inclusion of selected questions from the Coronavirus Health Impact Survey (CRISIS) questionnaire was administered again during the first 6-months of the COVID-19 pandemic and individuals who completed both the baseline assessment and the COVID-19 assessment were included for analyses ( = 46). Multivariate models were run to investigate the impacts of individual-, interpersonal-, and structural-level factors on change in EPDS scores across the postpartum period. Findings suggest that losing contact with social supports (β = 4.5, SE = 1.9, = .02) and individuals who reported a total household income of less than $75,000 (β = 3.4, SE = 1.7, = .05) were more likely to report significantly worsening postpartum depression scores compared to others. Recommendations to mitigate the stressors that have been amplified by the COVID-19 pandemic and resulting mental health disparities include screening all high-risk postpartum women for depression and anxiety during both postpartum and pediatric healthcare visits, providing informational flyers with tips related to healthy coping behaviors and free/affordable community resources, and linking individuals to peer-led support groups.
Exploring social connectedness, isolation, support, and recovery factors among women seeking substance use treatment.
Patton R, Chou J, Kestner T … +1 more , Feeney E
Women Health · 2024 Mar · PMID 38282278 · Publisher ↗
This cross-sectional study examined the relationship between social variables, recovery orientation, and recovery capital among a sample of = 30 women actively seeking substance use disorder treatment at a community-bas...
This cross-sectional study examined the relationship between social variables, recovery orientation, and recovery capital among a sample of = 30 women actively seeking substance use disorder treatment at a community-based facility in the Midwest United States. Results indicated a positive association between social connectedness, abstinence recovery orientation ( = .048) and social isolation ( = .010). Social isolation was positively associated with abstinence recovery orientation ( = .004) and negatively related to recovery capital ( = .003). Social support was positively correlated with positive expectancy ( = .030) and recovery capital ( = .033). Further, moderate/high alcohol use was related to lower normal living scores (t(28) = 3.10, = .004), lower recovery capital scores (t(28) = 4.15, < .000), and higher social isolation scores (t(28) = -2.53, = .017). Screening at moderate/high risk for cannabis use was related to lower normal living scores (t(28) = 3.01, = .005), and lower positive expectancy scores (t(28) = 3.03, = .005). Finally, screening for moderate/high risk for polysubstance use was related to lower normal living orientation (t(28) = 2.52, = .018) and recovery capital scores (t(28) = 2.79, = .009). Current findings may inform strategies for examining social connectedness and social isolation variables in future clinical practice, policy, and scholarship.
An exploratory study of mothers engaging in physical activity in rural communities.
Andreae SJ, Casey T, Lindberg A … +2 more , Doyle K, Pickett KA
Women Health · 2024 Mar · PMID 38273717 · Full text
Gender gaps in physical activity (PA) exist with women being less active than men. Multiple cultural and psychosocial factors influence women's ability to successfully negotiate barriers to PA and other health promoting...
Gender gaps in physical activity (PA) exist with women being less active than men. Multiple cultural and psychosocial factors influence women's ability to successfully negotiate barriers to PA and other health promoting behaviors. The goal of this exploratory descriptive study was to better understand the daily experiences of mothers in making health promoting decisions for themselves and their families. Semi-structured interviews ( = 17) were conducted with rural dwelling mothers who were the primary caregivers of children in the home. Participants were asked to share their experiences with PA and other health behaviors, focusing on their motivators, barriers, and facilitators. Interviews were audio-recorded, transcribed verbatim, and analyzed using thematic content analysis. Emerging themes focused on 1) feeling internal and external pressures to prioritize family's needs over one's health, 2) family exerting both positive and negative influences on health choices, and 3) living in a rural community often resulting in a lack of opportunities to engage in physical activity and feelings of being isolated from social networks. To close the gender gap in PA, interventions should support mothers in navigating their multiple roles and competing demands while engaging in health promoting behaviors such as physical activity.
Menstrual and psychosocial characteristics associated with high-risk of premenstrual dysphoric disorder among university students: a cross-sectional study.
Lee JJ, Wang T, Park J … +4 more , Lee B, Lee H, Li PWC, Choi EPH
Women Health · 2024 Feb · PMID 38267033 · Publisher ↗
Up to 92 percent of Chinese women of reproductive age have pre-menstrual syndrome (PMS). The severe form of PMS (i.e. pre-menstrual dysphoric disorder [PMDD]) negatively affects women's everyday functioning and reproduct...
Up to 92 percent of Chinese women of reproductive age have pre-menstrual syndrome (PMS). The severe form of PMS (i.e. pre-menstrual dysphoric disorder [PMDD]) negatively affects women's everyday functioning and reproductive health. This study examined the relationships between menstrual, psychosocial characteristics and the risk of PMDD among young Chinese women. A cross-sectional online survey was conducted among Chinese university students in Hong Kong. Logistic regression was used to compute adjusted odds ratio (aOR) for the association of high-risk PMDD with menstrual and psychosocial characteristics. A total of 541 Chinese university students were recruited. Approximately 53 percent of female students were at high risk of developing PMDD. The high-risk PMDD group was significantly associated with a heavy volume of menstrual flow (aOR = 2.17, 95 percent CI 1.06-4.45), irregular menstrual cycle (1.72, 1.17-2.52), high dysmenorrhea (2.80, 1.95-4.04) and older ages of menarche (0.67, 0.45-0.98) in the menstrual characteristics. In the psychosocial characteristics, high-risk PMDD was significantly associated with symptoms of anxiety (2.19, 1.48-3.32) and depression (2.22, 1.48-3.32), high loneliness (1.94, 1.34-2.79) and low resilience (2.21, 1.52-3.23) levels. Additionally, resilience had a potential moderating effect on the associations between the high risk of PMDD and anxiety, depression and loneliness. The development and delivery of interventions that can enhance resilience and manage psychological distress would be beneficial for young Chinese women's reproductive health.
Healthcare utilization before and during the COVID-19 pandemic among mothers and birthing parents with elevated levels of postpartum depression symptoms.
Luk V, Layton H, Savoy C … +2 more , Huh K, Van Lieshout RJ
Women Health · 2024 Feb · PMID 38258568 · Publisher ↗
Little is known about the healthcare utilization of mothers and birthing parents experiencing elevated levels of symptoms of postpartum depression (PPD), particularly during the COVID-19 pandemic. This study examined how...
Little is known about the healthcare utilization of mothers and birthing parents experiencing elevated levels of symptoms of postpartum depression (PPD), particularly during the COVID-19 pandemic. This study examined how healthcare utilization changed in these individuals during COVID-19. Individuals living in Ontario, Canada, with Edinburgh Postnatal Depression Scale Scores ≥ 10 were recruited into two separate randomized controlled trials of a 1-day intervention for PPD before (pre-COVID-19, = 441) and during the pandemic (COVID-19, = 287). Participants in both samples completed the same health resource use questionnaire, self-reporting the number of virtual and/or in-person visits to specific healthcare services over the three months preceding their treatment intervention. Use of medications, mental health care, primary care, hospital-based care, allied health care, and overall healthcare utilization were compared between the pre-COVID-19 and COVID-19 groups. While participants had higher levels of PPD symptoms during COVID-19, differences were not seen in the use of specific categories of care (e.g. mental health and primary care). However, before and after statistically adjusting for covariates, overall healthcare utilization decreased from an average of 9.5 visits prior to COVID-19 to 6.9 during COVID-19 ( < .001), a change that was at least partly contributed to by reductions in visits to allied health professionals (e.g. dentists and physiotherapists). Overall healthcare utilization decreased by 27 % in mothers and birthing parents seeking treatment for elevated levels of PPD symptoms during the COVID-19 pandemic in Ontario, Canada - despite higher levels of PPD symptoms - highlighting the need to support and address barriers to postpartum care.
Can't stop, won't stop - understanding anxiety's role in cyberchondria among pregnant women.
Šoštarić M, Jokić-Begić N, Vukušić Mijačika M
Women Health · 2024 Feb · PMID 38258443 · Publisher ↗
Online health research is common during pregnancy, especially if women are facing complications. Given the unpleasant emotions women experience after research, it is surprising that cyberchondria, excessive and repeated...
Online health research is common during pregnancy, especially if women are facing complications. Given the unpleasant emotions women experience after research, it is surprising that cyberchondria, excessive and repeated online health research caused by anxiety that intensifies such anxiety, has not been studied in pregnant women. Therefore, the aim of this study was to examine the predictors of cyberchondria among women with and without pregnancy complications, accounting for health anxiety (a worry regarding personal health) and pregnancy-specific anxiety (concerns related to pregnancy and childbirth). A total of 360 pregnant women completed a questionnaire consisted of Short Health Anxiety Inventory, Pregnancy Concerns Scale and Short Cyberchondria Scale. The results of one-way MANOVA showed that women who had medically complicated pregnancy had higher levels of health anxiety, pregnancy-specific anxiety and cyberchondria compared to those without complications. A hierarchical multiple regression analysis showed that health anxiety and pregnancy-specific anxiety were predictors of cyberchondria but had different roles depending on complications. Pregnancy-specific anxiety predicted cyberchondria in both groups above health anxiety. Health anxiety predicted cyberchondria only in women without complications. In conclusion, women with complications have a higher chance of experiencing cyberchondria. Pregnancy-specific and health anxiety are risk factors for cyberchondria in pregnant women.
Breastfeeding challenges and the impact of social support in Iranian Muslim mothers: A cross-sectional study.
Soltani S, Hosseinzadeh M, Mirghafourvand M … +2 more , Aghajari P, Burns E
Women Health · 2024 Feb · PMID 38258420 · Publisher ↗
Breast milk is the perfect food during infancy. Adequate support from family and health systems can be helpful to continue breastfeeding. This study aimed to determine the status of breastfeeding challenges and its relat...
Breast milk is the perfect food during infancy. Adequate support from family and health systems can be helpful to continue breastfeeding. This study aimed to determine the status of breastfeeding challenges and its relationship with social support and socio-demographic factors. In this correlational-descriptive study, 348 breastfeeding mothers were recruited using cluster random sampling from health care centers in Tabriz, Iran in 2022. Socio-demographic, breastfeeding challenges and social support questionnaires were used for data collection. Data were analyzed for descriptive and inferential statistics (Pearson correlation tests, independent t-test, one-way ANOVA and general linear model) using SPSS version 16. Difficulty in completing household tasks and breastfeeding at the same time (32.5 percent) was the most common challenge reported by mothers. There was an inverse and significant correlation between perceived social support and experiencing challenges ( = -0.199؛ = .001). Based on the adjusted general linear model, with increasing social support, the score of breastfeeding challenges decreased (B = -0.165; 95 percent CI: -0.07-0.25, < .001). Considering the relationship between perceived social support and the challenges experienced during breastfeeding, it can be concluded that adequate support from family along with training and guidance from health care providers can lead women to have better breastfeeding experiences and overcome breastfeeding problems.
Effect of physical activity on the relationship between adiposity and cardiac autonomic modulation in female breast cancer survivors: a longitudinal study.
Palma MR, Tebar WR, Beretta VS … +9 more , Vanderlei LCM, Fregonesi CEPT, Ribeiro FE, Caldeira DT, Ramos EMC, Cucato GG, Ferrari G, Ritti-Dias RM, Christofaro DGD
Women Health · 2024 Feb · PMID 38229419 · Publisher ↗
This longitudinal study aimed to analyze the influence of physical activity (PA) on the relationship between body adiposity and cardiac autonomic modulation (CAM) in women survivors of breast cancer. We collected body ad...
This longitudinal study aimed to analyze the influence of physical activity (PA) on the relationship between body adiposity and cardiac autonomic modulation (CAM) in women survivors of breast cancer. We collected body adiposity through electrical bioimpedance considering body fat percentage (BFP), CAM through heart rate variability (considering RMSSD, SDNN, PNN50, LF (m2), HF (m2), SD1 indexes and SD1/SD2 ratio) and PA through a questionnaire in 64 participants (58.0 ± 9.6 years), recruited through the local association of support for breast cancer and by direct indications from city mastologists. After insertion of PA into the multivariate statistical model, significant attenuation was observed in the relationship between body adiposity and CAM for the indices: SDNN (β = -0.94; 95 percent CI: -1.93; 0.04; = .060) and SD1/SD2 (β = -0.01;95 percent CI = -0.02; 0.001; = .065). In conclusion, it was observed that PA was able to mitigate the relationships between BFP and CAM (considering SDNN index and SD1/SD2 ratio) in breast cancer survivors.
Spousal support and dyadic adjustment in the early postpartum period.
Kılıç S, Can R, Yilmaz SD
Women Health · 2024 Feb · PMID 38221674 · Publisher ↗
In the study, we aimed to investigate the effects of perceived spousal support and dyadic adjustment on the psychological well-being of women in the early postpartum period. This descriptive and correlational study consi...
In the study, we aimed to investigate the effects of perceived spousal support and dyadic adjustment on the psychological well-being of women in the early postpartum period. This descriptive and correlational study consisted of 367 women giving birth in the postpartum department between 15th July and 31st October 2022. The data were collected using the Personal Information Form, the Perceived Spousal Support Among Women in Early Postpartum Period (PSSAWEPP), the Revised Dyadic Adjustment Scale (RDAS), and the Psychological Well-Being Scale (PWBS). The average scores of PSSAWEPP, RDAS, and PWBS in the mothers were found as 61.79 ± 7.73, 54.16 ± 6.28, and 45.87 ± 5.74, respectively. The elevated scores of perceived spousal support (β = 0.234, < .001) and dyadic adjustment (β = 0.270, < .001) of women led to a significant increase in the level of psychological well-being. In conclusion, the support received by women from spouses and dyadic adjustment affect the psychological well-being of women in the early postpartum period.
The effect of Pilates exercise during pregnancy on delivery outcomes: a systematic review and meta-analysis.
Baradwan S, Khadawardi K, Alayed NM … +5 more , Akkour KM, Mahmoud MS, Abdelhakim AM, Sunoqrot M, Abdel Hamid AS
Women Health · 2024 Feb · PMID 38221667 · Publisher ↗
A systematic review and meta-analysis were conducted to investigate the effectiveness of the Pilates exercise program during pregnancy on different delivery outcomes. Various databases were searched from inception until...
A systematic review and meta-analysis were conducted to investigate the effectiveness of the Pilates exercise program during pregnancy on different delivery outcomes. Various databases were searched from inception until November 2022. The included studies compared Pilates exercise to routine antenatal care in pregnant women. The primary outcomes assessed were vaginal and cesarean delivery rates, as well as labor duration. Secondary outcomes included episiotomy incidence, Apgar scores, and epidural analgesia. Seven studies met the inclusion criteria, involving a total of 1,003 patients. Results indicated a significant increase in the vaginal delivery rate among the Pilates exercise group compared to the control group ( < .001). Moreover, the Pilates exercise group exhibited significantly reduced rates of cesarean delivery and shorter labor duration. Pilates exercise was associated with a significant decline in the incidence of episiotomy and the number of women requiring epidural analgesia during delivery ( < .001 & = .008). In addition, Apgar scores at one and five minutes were significantly higher in the Pilates exercise group compared to the control group ( < .001). In conclusion, Pilates exercise during pregnancy has a positive effect on maternal outcomes and Apgar scores. However, more trials are needed to confirm these findings.
Women's health in 2024: change now for tomorrow will be too late.
Carneiro MM
Women Health · 2024 Jan · PMID 38154485 · Publisher ↗
Abstract loading — click title to view on PubMed.
Uterine leiomyomata claim rate estimates and demographic characteristics by county. Florida, 2010-2019.
Sherifi SK, Odahowski CL, López Castillo H
Women Health · 2024 Jan · PMID 38154484 · Publisher ↗
To describe the demographic characteristics and estimate the uterine leiomyomata claim rates (ULCRs) by women 18 years and older in Florida, we conducted a cross-sectional analysis of the 2010-2019 administrative claims...
To describe the demographic characteristics and estimate the uterine leiomyomata claim rates (ULCRs) by women 18 years and older in Florida, we conducted a cross-sectional analysis of the 2010-2019 administrative claims for uterine leiomyomata and associated study variables (age, race, ethnicity, county of residence, anatomic site, length of stay, and additional diagnoses). ULCR ratios were estimated by race and ethnicity, using ULCR for non-Hispanic White women as the reference group. We identified 232,475 claims, most of which were among non-Hispanic White women in their forties. The overall ULCR estimate [95 percent CI] was 284.8 [284.21, 285.39] per 100,000 women 18 years and older, with a small, nonsignificant trend to increase over time ( = .310; = .094). Black, Hispanic, and other women of color presented with higher ULCR ratios (4.84, 1.87, and 1.58, respectively). Urban counties had significantly higher ULCRs than suburban and rural counties. While non-Hispanic White women had the highest frequency of ULCRs, women of color-especially Black women-presented with significantly higher ULCR ratios. The epidemiologic profile of uterine leiomyomata in terms of age, race, ethnicity, and geographic location points to unmet healthcare needs among specific demographic and geographic groups of women in Florida.
Influence of postdiagnostic aspirin use on clinical outcomes of women with breast cancer: a meta-analysis.
Wu C, Hu M, Zhang S … +3 more , Zhang J, Shen L, Shen X
Women Health · 2024 Feb · PMID 38151762 · Publisher ↗
We examined the association between postdiagnostic aspirin use and recurrence and disease-specific mortality among women with breast cancer in a meta-analysis. The PubMed, Embase, and Web of Science databases were search...
We examined the association between postdiagnostic aspirin use and recurrence and disease-specific mortality among women with breast cancer in a meta-analysis. The PubMed, Embase, and Web of Science databases were searched to identify observational studies with longitudinal follow-ups according to the aim of the meta-analysis. Combining the results was achieved using a random-effects model that included inter-study heterogeneity. Fifteen cohort studies with 131,636 women with breast cancer were included. Based on a meta-analysis, women who took aspirin after being diagnosed with breast cancer had a lower risk of breast cancer recurrence (adjusted risk ratio [RR]: 0.77, 95 percent confidence interval [CI]: 0.63 to 0.95, = .02; I = 72 percent) and breast cancer specific mortality (adjusted RR: 0.73, 95 percent CI: 0.60 to 0.90, = .004; I = 80 percent) than those who did not use aspirin. The certainty of the evidence was rated using the Grading of Recommendations Assessment, Development, and Evaluations scoring system showed moderate certainty for both the outcomes because significant inconsistency was observed. In conclusion, aspirin use after diagnosis might be associated with reduced recurrence and disease-specific mortality in women with breast cancer.
Regulatory mechanism of GPER in the invasion and migration of ectopic endometrial stromal cells in endometriosis.
Shi H, Xu K, Huang M … +2 more , Mao M, Ou J
Women Health · 2024 Feb · PMID 38148599 · Publisher ↗
Endometriosis (EMS) is a chronic inflammatory disorder of high incidence that causes serious reproductive consequences. High estrogen production is a consistently observed endocrine feature of EMS. The present study aims...
Endometriosis (EMS) is a chronic inflammatory disorder of high incidence that causes serious reproductive consequences. High estrogen production is a consistently observed endocrine feature of EMS. The present study aims to probe the molecular mechanism of G protein-coupled estrogen receptor 1 (GPER) in the invasion and migration of ectopic endometrial stromal cells (Ect-ESCs) and provides a new rationale for EMS treatment. Eutopic and ectopic endometrial tissues were collected from 41 EMS patients, and primary ESCs were separated. GPER, miR-16-5p, and miR-103a-3p levels in cells and tissues were determined by qRT-PCR or Western blot assay. Cell viability, proliferation, invasion, and migration were evaluated by CCK-8, colony formation, and Transwell assays. The upstream miRNAs of GPER were predicted by databases, and dual-luciferase assay was performed to validate the binding of miR-16-5p and miR-103a-3p to GPER 3'UTR. GPER was highly expressed in EMS tissues and Ect-ESCs. Inhibition of GPER mitigated the proliferation, invasion, and migration of Ect-ESCs. GPER was regulated by miR-16-5p and miR-103a-3p. Overexpression of miR-16-5p and miR-103a-3p negatively regulated GPER expression and inhibited the invasion and migration of Ect-ESC. In conclusion, GPER promoted the invasion and migration of Ect-ESCs, which can be reversed by upstream miR-16-5p and miR-103a-3p.
Improving menstrual health knowledge among girls from Iran: the effectiveness of educational health belief model.
Yari A, Kabiri B, Afzali Harsini P … +1 more , Khani Jeihooni A
Women Health · 2024 Jan · PMID 38114075 · Publisher ↗
Menstrual health education is one of the important aspects of health education during adolescence in girls. The aim of this study was to evaluate the effectiveness of the Health Belief Model (HBM) on promoting Knowledge...
Menstrual health education is one of the important aspects of health education during adolescence in girls. The aim of this study was to evaluate the effectiveness of the Health Belief Model (HBM) on promoting Knowledge of menstrual health in female students of Fasa City, Fars Province, Iran. This quasi-experimental study was done on 200 high school girls (100 experimental and 100 control groups) who were selected using a random sampling method in Fasa City, Fars Province, Iran, in 2019-2020. The educational intervention for the experimental group consisted of 6 training sessions of 50-55 minutes through lectures, Q & A, group discussion, educational posters and pamphlets, videoclips, and PowerPoint. A scale of this study consisted of two parts; demographic information, and HBM constructs were used to determine the behaviors of menstrual health in two (before and 3 months after intervention) times. The mean age of students in the experimental and control groups was 13.40 ± 0.68 and 13.34 ± 0.72 years. The results showed that before the educational intervention, there was no significant difference between the experimental and control groups in terms of knowledge, perceived sensitivity, perceived severity, perceived benefits, perceived barriers, self-efficacy, cues to action and performance; however, three months after the intervention, the experimental group showed a significant increase in each of the mentioned variables except the perceived barriers. Based on the present study, education based on the health belief model structures is effective in improving Knowledge of menstrual health and this model can be used to prevent and reduce the symptoms of premenstrual syndrome.
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