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Nutr Health [JOURNAL]

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What do ready-to-eat meals sold in supermarkets offer? Nutritional content, cost, and beyond.

Guldemir O, Hizli-Guldemir H

Nutr Health · 2025 Nov · PMID 41218002 · Publisher ↗

BackgroundThere is a paucity of research on the characteristics of this ever-growing market in Türkiye, where consumer demand has been rapidly increasing. Also, the environmental impact of the packaging materials is anot... BackgroundThere is a paucity of research on the characteristics of this ever-growing market in Türkiye, where consumer demand has been rapidly increasing. Also, the environmental impact of the packaging materials is another current issue that needs to be focused on for these disposable products.AimThis study aims to analyze and reveal the nutritional contents, costs, and some other characteristics, such as allergenic contents and packaging materials, of the ready-to-eat meals (RTEs) sold in supermarkets in Türkiye.MethodsThe label information of 245 products was noted, and these products were categorized as main dishes, side dishes, and soups; subsequently, their 100 g and portion-based nutritional contents were compared with recommendations.SummaryMain dishes contain higher energy, fat, saturated fat, and proteins when compared to side dishes and soups (p < 0.001). In the side dishes, the amount of fat and protein increases directly with the price. The amount of energy, saturated fat, and protein decreases as the portion weight increases (p < 0.05). The amount of salt in the main and side dish categories is above the limits (+0.3 g and +0.14 g, respectively). Wheat-based gluten was the most common allergen and plastic was found the most commonly used packaging material. The energy contents of the RTEs were found within the recommendations. It is also noteworthy that these products contain higher amounts of salt, and they also contain at least one food allergen.

Effect of vitamin E supplementation on orthodontic tooth movement: A systematic review of studies in animal models.

Blaskovic SR, Rossouw PE, Javed F

Nutr Health · 2026 Mar · PMID 41212663 · Publisher ↗

There are no studies that have systematically reviewed the currently available evidence on the influence of vitamin E-supplementation on orthodontic tooth movement (OTM). The objective of this systematic review is to as... There are no studies that have systematically reviewed the currently available evidence on the influence of vitamin E-supplementation on orthodontic tooth movement (OTM). The objective of this systematic review is to assess the influence of vitamin E-supplementation on OTM. Indexed databases were searched without time and language restrictions up to and including October 2025. Original studies addressing the focused question "Does vitamin E-supplementation affect OTM?" were included. Different combinations (Boolean operators) of keywords were used, and independent reviewers screened the studies for eligibility. The Risk of bias (RoB) and quality of studies were assessed using the Systematic Review Centre for Laboratory Animal Experimentation tool and Grading of Recommendations, Assessment, Development, and Evaluation analysis, respectively. Disagreements were resolved via discussion. Four studies performed on animal models were included. The magnitude of the orthodontic forces administered ranged from 10 g to 50 g. The route and dosage of vitamin E-supplementation varied between studies. One study showed no influence of vitamin E-supplementation on OTM; and three reported that vitamin E-supplementation increases OTM. Three studies reported that vitamin E-supplementation increases osteoblast activity and one reported that vitamin E-supplementation increases osteoclastic activity. Prior sample-size-estimation was performed in none of the studies. All studies had an unclear RoB and a low overall certainty of evidence. Since a limited number of preclinical studies, characterized by a high RoB and a low certainty of evidence fulfilled the eligibility criteria, the influence of vitamin E-supplementation on OTM remains inconclusive. Further well-designed, blinded, and power-adjusted randomized controlled trials with standardized vitamin E-supplementation related parameters are needed.

Food insecurity experience of pregnant and lactating women from rural households in Tamil Nadu, India during COVID lockdown - Empirical evidence from household air pollution intervention network study.

Aravindalochanan V, Garg SS, Thangavel G … +15 more , Ramasamy R, Rajan OP, Natarajan PK, Gopalkrishna MS, Loganathan S, Sambandam S, Mukhopadhyay K, Sinharoy S, Ramakrishnan U, Balakrishnan K, Jabbarzadeh S, Waller L, Clasen TF, Peel J, Checkley W

Nutr Health · 2025 Nov · PMID 41197241 · Full text

BackgroundFood insecurity is a major public health concern in India because of the high prevalence of malnourishment. The COVID-19 pandemic-induced lockdowns caused widespread disruptions in food systems. However, limite... BackgroundFood insecurity is a major public health concern in India because of the high prevalence of malnourishment. The COVID-19 pandemic-induced lockdowns caused widespread disruptions in food systems. However, limited empirical evidence on food insecurity trends among vulnerable populations have been available.ObjectivesWe utilised longitudinal data collected from the Household Air Pollution Intervention Network (HAPIN) study in Tamil Nadu, India, between January to September 2020, in order understand the impact of the COVID pandemic on household food insecurity (HFI) in rural households.MethodsWe performed repeat (n = 4) administrations of the Food Insecurity Experience Scale tool developed by the Food and Agricultural Organisation among households with pregnant or lactating mothers, enrolled in the HAPIN study (n = 676) to include pre-COVID lockdown, during lockdown, immediately after lockdown and post-COVID lockdown periods.ResultsThe overall prevalence of HFI during the pre-COVID lockdown was 4% with a sharp fivefold increase during the lockdown period. The HFI decreased to 17% in the immediately after lockdown period and stabilised at around 7% in the post-COVID lockdown period.ConclusionsHigh levels of food insecurity (even if transient) that was observed during lockdown periods of the COVID 19 pandemic in rural Tamil Nadu indicate the potential for increased health risks for pregnant women and lactating mothers in low-income households.

Epidemiological trends and burden of nutritional deficiencies among infants in India: Evidences from the Global Burden of Disease study, 1990-2021.

Roy C, Kalbalia P

Nutr Health · 2025 Nov · PMID 41191036 · Publisher ↗

BackgroundNutritional deficiencies among infants continue to be a significant contributor to the disease burden in India.AimTherefore, this study analyses the annual trends and overall burden of nutritional deficiencies... BackgroundNutritional deficiencies among infants continue to be a significant contributor to the disease burden in India.AimTherefore, this study analyses the annual trends and overall burden of nutritional deficiencies among infants and forecasts the prevalence in India.MethodsData were extracted from the Global Burden of Disease (GBD) 2021 study to analyse temporal trends in nutritional deficiencies among infants in India from 1990 to 2021. Joinpoint regression analysis was employed to assess changes over time, while the ARIMA model was used for forecasting. Subnational-level Sustainable Development Goals (SDGS) performance data were retrieved from the National Institute for Transforming India (NITI) Aayog dashboard to understand the association between nutritional deficiencies and SDGs, presented through a heat map created using MS Excel.SummaryBetween 1990 and 2021, the prevalence of nutritional deficiencies among infants in India declined from 798.69 (95% UI: 765.85 to 830.22) to 683.54 (95% UI: 664.02 to 702.93) per 1000 live births, with an annual percentage change of -14.42. Despite this overall improvement, substantial interstate disparities persist. In 2021, Bihar [763.04 (95% UI: 723.24 to 799.46)], Jharkhand [756.8 (95% UI: 729.3 to 787.24)], and Uttar Pradesh [726.57 (95% UI: 697.24 to 758.62)] recorded the highest prevalence, while Mizoram [408.87 (95% UI: 367.44 to 455.12)] reported the lowest. Despite a measurable decline in the prevalence of nutritional deficiencies among infants in India from 1990 to 2021, the condition remains a major public health concern. The persistence of significant regional disparities, particularly in states such as Bihar, Jharkhand, and Uttar Pradesh, reflects underlying systemic inequities in healthcare access and nutrition delivery. The observed association between subnational SDGs performance and nutritional outcomes underlines the need to enhance primary healthcare services and strengthen nutritional support systems, especially in lagging regions.

Opportunity cost of tobacco consumption on household nutrition in India: A state-level analysis.

Khatoon S, Bhattacharya P, Mukherjee N … +2 more , Yadav A, Lal P

Nutr Health · 2026 May · PMID 41182974 · Publisher ↗

The consumption of tobacco in low-income countries is linked to poverty and malnutrition, particularly in India, where 14% of the population suffers from undernourishment. This study aims to assess the opportunity costs... The consumption of tobacco in low-income countries is linked to poverty and malnutrition, particularly in India, where 14% of the population suffers from undernourishment. This study aims to assess the opportunity costs of tobacco expenditure by quantifying nutritional losses and potential enhancements in household-level food energy status if funds allocated for tobacco were redirected towards food consumption in all Indian states. This study is based on secondary data obtained from NSSO 68th Round, 2011-12. The analysis involves the calculation of the costs of tobacco products along with essential cereals and proteins in order to assess the nutritional deficiencies experienced by households in different states. The National Institute of Nutrition's recommended "My Plate" per day food requirements in 2020, and calorie requirements for males and females as recommended by Recommended Dietary Allowance (RDA), 2020 were considered to calculate the opportunity cost of tobacco expenses. Tobacco accounts for 3.6% of food expenditure in rural India and 2.9% in Urban India. Highest tobacco expenditure as proportion of food expenditure in rural India was found in Rajasthan (7.5%), Maharashtra (5.4%), North-eastern states (4.9%) and Haryana (4.8%) while Madhya Pradesh (3.5%), Maharashtra (3.4%), Rajasthan and North-east (3.3%) have the highest proportion in urban India. The findings suggest that reduction of tobacco expenses and proper re-allocation of resources will facilitate improvement and optimization of tobacco prevention and control strategies.

Eating patterns and dyslipidemia in adolescents from a capital in northeastern Brazil: A causal inference analysis.

Pires BRF, Ribeiro CC, França AKTDC … +4 more , Rodrigues ESM, Alves JDA, Bogea EG, Thomaz EBAF

Nutr Health · 2026 Mar · PMID 41182906 · Publisher ↗

To analyze the association between dietary patterns and dyslipidemia in adolescents. This is a cross-sectional study conducted with 363 adolescents of both genders, aged 17-18 years, from public schools in Sao Luis, in... To analyze the association between dietary patterns and dyslipidemia in adolescents. This is a cross-sectional study conducted with 363 adolescents of both genders, aged 17-18 years, from public schools in Sao Luis, in the state of Maranhão, Brazil. Adolescents with alteration in at least one of the following conditions were considered to have dyslipidemia: total cholesterol (TC), low-density lipoprotein (LDL-c), high-density lipoprotein (HDL-c), triglycerides (TG), Castelli I and II Indices, and non-HDL-c. Food consumption was assessed through the food frequency questionnaire, and dietary patterns were identified using the principal component analysis. The directed acyclic graph was elaborated to select the variables that were controlled in the analysis of the effect of dietary patterns on dyslipidemias, and the final sample of the study was weighted by the inverse probability of selection for these variables, using a doubly robust method. Adolescents were 17.3 ± 0.5 years, mostly women (55.6%), brown (66.6%), with one to three minimum wages (38.3%), and maternal education from 8 to 12 years (46.4%). Three dietary patterns were identified: Western, Healthy, and Traditional. Most adolescents had dyslipidemia, and inadequate HDL-c levels were the main dyslipidemia found (44.9%). There was no significant difference in the occurrence of dyslipidemia among the three dietary patterns identified (healthy: -0.015; CI: -0.11; 0.08;  = 0.773; traditional: 0.04; CI: -0.06; 0.13;  = 0.542; Western: -0.064, CI: -0.16; 0.03;  = 0.201). The prevalence of dyslipidemia is high among adolescents from one city in a poor Brazilian region, but it was not explained by the dietary patterns identified in this study.

Precision nutrition: Paving the path from potential to practice through systems science and ethical translation.

Fayyaz K, Khalid N

Nutr Health · 2025 Dec · PMID 41172053 · Publisher ↗

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Glycemic index determination of Cacao fruit pulp - an edible by-product in cocoa bean production.

Jenkins AL, Au-Yeung R, Campbell J … +5 more , Unlu E, Bussy U, Canene Adams K, Mogollón Jijón MA, Soundara Manickam S

Nutr Health · 2026 Mar · PMID 41172034 · Publisher ↗

BackgroundCacao fruit pulp is a sweet and fruity carbohydrate-rich edible mucilage from the cacao fruit that is often discarded during cocoa bean production. While there is interest in re-purposing the pulp for human con... BackgroundCacao fruit pulp is a sweet and fruity carbohydrate-rich edible mucilage from the cacao fruit that is often discarded during cocoa bean production. While there is interest in re-purposing the pulp for human consumption, no study to date has assessed the glycemic response. to determine the glycemic index (GI) of cocoa pulp using the ISO method.MethodsIn an acute, open-labelled, randomized design, 10 individuals without diabetes (age: 42.0 ± 17.0 years, BMI: 28.0 ± 4.3 kg/m) were studied over 120 min after consuming 25 g available carbohydrate portions of cacao pulp or dextrose on separate occasions.SummaryThe GI of cacao pulp was 51 ± 4 and incremental area under the curve for cacao pulp was 50% lower than dextrose (83.5 ± 14.3 vs. 166.1 ± 30.6 mmol × min/L, p = 0.001). Postprandial glucose levels were also significantly lower for cacao pulp at 15, 30 and 45 min (p < 0.02). This study demonstrated that cacao pulp is a low GI food and may have uses in attenuating postprandial glucose.

Nutrition and integrated healthcare knowledge, attitudes, and prospective practices among healthcare students: A theoretical model survey analysis.

Dyett P, Legall G, Foster-Nicholas LA … +5 more , Mitchell C, Adams-Robinson A, Jones-Oyefeso V, Valley-Thom P, Sealey-Tobias V

Nutr Health · 2025 Oct · PMID 41166165 · Publisher ↗

BackgroundThe understanding, appreciation, and application of integrated healthcare by health professional students can shape future health promotion and intervention strategies. This involves blending nutrition, lifesty... BackgroundThe understanding, appreciation, and application of integrated healthcare by health professional students can shape future health promotion and intervention strategies. This involves blending nutrition, lifestyle, and conventional medical approaches from educational curricula to the professional practice arena.AimsTo assess targeted healthcare students from three institutions for associations between demographics and survey parameters of knowledge, attitudes, and practices regarding nutrition and integrated healthcare approaches, and to evaluate students' prospects for integrating lifestyle-based and conventional healthcare approaches, within the context of the Knowledge-Attitude-Practice (KAP) model.MethodsSurvey questions and responses based on a previously validated electronic questionnaire were used to evaluate university-level healthcare students enrolled in the nutrition (n = 92) and nursing (n = 195) disciplines. Demographic data were analyzed alongside scored items assessing knowledge, attitudes, and practices. Descriptive statistics, chi-square tests, Kruskal-Wallis tests, Dunn-Bonferroni tests, Spearman's rho, and partial correlations were conducted.ResultsMost students demonstrated high overall knowledge (74%), attitude (93%), and practice (84%) scores. However, significant differences (p < 0.05) in the knowledge scores were observed across institutions, academic levels, and disciplines. Although relatively weak, knowledge had a significant and positive relationship with attitude (rho = 0.263, < 0.001), but not with practice. The strength of relationships was moderated by controlling for socio-demographic factors such as specific degree/discipline, institutional and environmental context, race, religion, and age.ConclusionThe findings of this study highlight the benefits of using KAP-based learning outcomes for healthcare training programs and demonstrate its relevance in informing tailored educational strategies and clinical interventions and policy initiatives that support integrated healthcare approaches.

Food supplements - the labelling challenges.

Campos MJ, Pena A

Nutr Health · 2026 May · PMID 41148283 · Full text

Food supplements (FSs) labelling presents challenges for the food and pharmaceutical industries as well as regulatory authorities. Effective standardisation, improvement, and interpretation of FS labelling are essential... Food supplements (FSs) labelling presents challenges for the food and pharmaceutical industries as well as regulatory authorities. Effective standardisation, improvement, and interpretation of FS labelling are essential for healthcare professionals (HPs) to provide accurate advice on these products. This article aims to address the regulatory and labelling complexities of these special foods, highlighting the need for more complete harmonisation all over the world and, at least, on the European Union (EU) market. To help improve HP's knowledge concerning FS labelling, a critical analysis of relevant Global and European legislation and publications concerning FS labelling was conducted. It was found that FS labelling legislation is comprehensive. However, areas such as health claims and permitted dosages (illustrated by the case of biotin) require in-depth knowledge to develop guidelines to support HP interventions. The lack of harmonisation in EU regulation, for example, is a challenge that makes it difficult for HP to interpret information. The introduction of databases, such as the one developed by the Office of Dietary Supplements in the USA, which includes images of label quantities, serves as a model for providing transparent information. An HP with a better understanding of FS labelling is essential to provide accurate patient guidance and ensure the safety of FS consumption. The creation of resources and training programs to empower HPs is crucial to ensure quality advice and safe product use.

Low-carbohydrate and high-protein diet may impair working memory via downregulation of hypothalamic T1R3 in mice.

Shima T

Nutr Health · 2026 Mar · PMID 41124336 · Publisher ↗

BackgroundLow-carbohydrate, high-protein (LC-HP) diet declines working memory function in wild-type mice. Since the glucose sensor T1R3 is critical for cognitive function, it was unknown whether the LC-HP diet-induced me... BackgroundLow-carbohydrate, high-protein (LC-HP) diet declines working memory function in wild-type mice. Since the glucose sensor T1R3 is critical for cognitive function, it was unknown whether the LC-HP diet-induced memory declines involve altered brain T1R3 levels.AimTo examine the involvement of central T1R3 in LC-HP diet-induced memory declines.MethodsNine-week-old male C57BL/6J mice were assigned to either an LC-HP diet (25.1% carbohydrate, 57.2% protein, 17.7% fat) or a control diet (58.9% carbohydrate, 24.0% protein, 17.1% fat). Another set of standard-diet-fed mice received either hypothalamic small interfering RNA (siRNA) or a negative control delivered via the osmotic pump. After four weeks, all mice underwent a Y-maze test, and messenger RNA (mRNA) expression analysis in the hippocampus and hypothalamus.ResultsThe LC-HP diet declined working memory and hypothalamic mRNA levels by about 27% ( < 0.01 and  < 0.05, respectively). Furthermore, hypothalamic -siRNA administration led to working memory deficits ( < 0.05).ConclusionHypothalamic T1R3 might be involved in LC-HP diet-induced working memory decline.

The influence of intermittent fasting on body metrics, lipid profile, and physical performance in young and middle-aged men.

Gasmi M, Hawani A, Ben Chikha A … +4 more , Eken Ö, Marsigliante S, Muscella A, Khalifa R

Nutr Health · 2025 Oct · PMID 41092045 · Publisher ↗

Intermittent fasting (IF) is increasingly adopted for weight and metabolic health management, yet its impact on lipid profile and physical performance in young and middle-aged men remains unclear. The present study exam... Intermittent fasting (IF) is increasingly adopted for weight and metabolic health management, yet its impact on lipid profile and physical performance in young and middle-aged men remains unclear. The present study examined the effect of a five-month (IF) on body composition, lipid profile, and physical performance. A randomized controlled trial was conducted to evaluate the impact of this eating pattern. Forty active male participants were divided into two age groups (a young group from 23 to 28 years and a middle-aged group from 46 to 59 years) and then randomly assigned to experimental (young experimental group (YE), middle-aged experimental group (ME)) or control groups (young control group, middle-aged control group). Before and after the five-month (IF) intervention (4 days per week), all participants performed the Running-based Anaerobic Sprint and the Test Blood for the determination of lipids profile. Both young (YE) and middle-aged (ME) experimental groups showed significant reductions in weight ( = 0.012 for YE and  = 0.011 for ME), body mass index (BMI) ( = 0.011 for YE and  = 0.012 for ME) and fat-free mass ( = 0.004 for YE and  = 0.043 for ME) compared to control groups. Analysis of variance (ANOVA) revealed significant main effects of time and group for weight ( < 0.001;  = 0.012), BMI ( = 0.012;  = 0.038), and fat-free mass ( = 0.023;  = 0.037), with significant time × group interaction for weight ( = 0.017) and trends for BMI ( = 0.048) and fat-free mass ( = 0.07); no significant effects were observed for body fat percentage ( > 0.05). In addition, our results showed that (IF) was associated with significant decrease in total cholesterol ( = 0.004 for YE and  = 0.0024 for ME) and high-density lipoprotein (HDL) levels ( = 0.004 for YE and  = 0.009 for ME) in both experimental groups. Low-density lipoprotein decreased significantly only in the young IF group ( = 0.041). However, IF did not affect triglyceride levels or physical performance. ANOVA revealed a significant interaction between time and group for HDL ( < 0.001), with greater reductions in middle-aged participants, and a significant group effect for triglycerides ( < 0.001), which were higher in middle-aged groups at both time points. These results suggest that while IF can positively influence body composition and is associated with selective changes in lipid profiles, its effects on triglycerides and physical performance may be limited. These findings underscore the need for further research to explore the long-term metabolic implications of IF, as well as potential age-related differences in response to fasting regimens.

A cross-sectional analysis of baseline diet quality among participants enrolled in delicious eating for life in the southern homes weight loss randomized trial.

Saraiya VM, Fung TT, Pitts SBJ … +9 more , Wu Q, Berkowitz SA, Skinner HG, Thaxton CK, Alick CL, Sotres-Alvarez D, Evenson KR, Samuel-Hodge CD, Keyserling TC

Nutr Health · 2025 Oct · PMID 41092043 · Publisher ↗

A healthful dietary pattern, which typically includes regular and generous consumption of healthful fats and carbohydrates, reduces the risk for obesity-related morbidity and mortality. To assess the potential for improv... A healthful dietary pattern, which typically includes regular and generous consumption of healthful fats and carbohydrates, reduces the risk for obesity-related morbidity and mortality. To assess the potential for improving diet quality in the context of a weight loss intervention, it is important to assess baseline measures of diet quality. To describe the baseline diet quality among participants in a behavioral weight-loss clinical trial. Participants were referred to this study by primary care clinicians. The Harvard Food Frequency Questionnaire was used to assess dietary intake, and items from this instrument were used to calculate the Alternative Health Eating Index (AHEI)-2010, Dietary Approaches to Stop Hypertension (DASH), and Alternate Mediterranean Diet index scores. Reflection spectroscopy was used to objectively assess skin carotenoids. Among 360 participants, the mean age was 54.7 (SD 12.0) years, 44.1% were male, 36.7% self-identified as Black, 32.5% had type 2 diabetes mellitus, and the median body mass index was 35.1 kg/m (Q1-Q3 32.4-40.2). Median energy intake from fat was 37.2%, including 12.1% from saturated fat, while total carbohydrate intake was 44.8% with total fiber intake 17.0 g/day (Q1-Q3 12.3-23.4). In multivariable models, younger age and Black race were significantly associated with lower AHEI-2010 and DASH scores, representing lower diet quality. Study participants' dietary intakes were high in saturated fat and low in dietary fiber, underscoring the need for weight loss interventions to focus on diet quality as well as energy restriction.

The impact of maternal ketonuria with pregnancy outcome and optimal carbohydrate intake in pregnant women.

Sakane N, Suganuma A, Domichi M … +1 more , Hayashi I

Nutr Health · 2025 Oct · PMID 41092035 · Publisher ↗

BackgroundKetonuria during pregnancy, potentially arising from inadequate carbohydrate intake or elevated energy demands, has an uncertain association with adverse outcomes, particularly preterm birth.AimsThis study aime... BackgroundKetonuria during pregnancy, potentially arising from inadequate carbohydrate intake or elevated energy demands, has an uncertain association with adverse outcomes, particularly preterm birth.AimsThis study aimed to examine the relationship between maternal ketonuria and pregnancy outcomes, and to identify the carbohydrate intake level that may help prevent ketonuria in pregnant women.MethodsIn this prospective study, 349 pregnant women were assessed for ketonuria using the nitroprusside method, categorized into mild, moderate, and severe. Dietary carbohydrate intake was measured via a food frequency questionnaire. Receiver operating characteristic analysis identified trimester-specific carbohydrate thresholds for moderate/severe ketonuria. Logistic regression evaluated associations between ketonuria and preterm birth, adjusting for confounders including prepregnancy body mass index (BMI), smoking, blood pressure, hemoglobin, and glucose levels.ResultsKetonuria prevalence was 12.6% (mild), 1.7% (moderate), and 2.3% (severe). Ketonuria was associated with higher prepregnancy BMI, smoking history, and increased preterm birth. First-trimester ketonuria significantly increased preterm birth risk (adjusted OR 5.76; 95% CI [1.73-19.1];  = .004). Carbohydrate intake thresholds predicting moderate/severe ketonuria were 187 g (first trimester), 170 g (second), and 143 g (third).ConclusionsEarly pregnancy ketonuria is independently associated with preterm birth. Adequate trimester-specific carbohydrate intake may help prevent ketonuria, highlighting its importance in prenatal care.

Understanding hypoglycemia: Validation of the hypoglycemic attitudes and behavior scale in Turkish type 2 diabetes patients.

Uzlu G, Pulat Demir H

Nutr Health · 2025 Oct · PMID 41092023 · Publisher ↗

BackgroundThe Hypoglycemic Attitudes and Behavior Scale (HABS) is designed to assess key aspects of hypoglycemia-related experiences.AimThis study aimed to evaluate the validity and reliability of the Turkish version of... BackgroundThe Hypoglycemic Attitudes and Behavior Scale (HABS) is designed to assess key aspects of hypoglycemia-related experiences.AimThis study aimed to evaluate the validity and reliability of the Turkish version of HABS in patients with type 2 diabetes mellitus (T2DM), including both insulin users and nonusers.MethodsA total of 181 patients with T2DM (mean age 58.76 ± 10.17 years), including both insulin users and non-users, participated in this study. Exploratory factor analysis (EFA) was performed to determine the factor structure, while confirmatory factor analysis (CFA) was conducted to assess the model fit. Internal consistency reliability was evaluated via Cronbach's alpha (α) coefficient and the test-retest method. Convergent validity was examined by analyzing the correlation between the HABS and the Hypoglycemia Fear Scale (HFS).ResultsCronbach's α coefficient values for the anxiety, avoidance, and confidence sub-dimensions were 0.68, 0.75, and 0.82, respectively. Test-retest correlations for the subdimensions were positive, moderate to high, and statistically significant ( < 0.001). EFA revealed a three-factor structure, similar to the original HABS, with three items removed. CFA confirmed that the modified model had a good fit. A significant positive correlation was found between HABS and HFS subdimensions ( < 0.001), supporting convergent validity.ConclusionsThe Turkish version of HABS demonstrates strong psychometric properties, making it a valuable tool for assessing hypoglycemia-related attitudes and behaviors in Turkish T2DM patients and informing clinical practice.

The effects of 8-week creatine supplementation with and without ubiquinol on sperm quality biomarkers in normospermic and oligospermic men: A randomized controlled pilot trial.

Nedeljkovic D, Todorovic N, Javorac D … +11 more , Baltic S, Vranes M, Panic J, Kladar N, Ratgeber L, Betlehem J, Acs P, Stea TH, Engeset D, Stajer V, Ostojic SM

Nutr Health · 2025 Oct · PMID 41052075 · Publisher ↗

BackgroundNo studies have investigated whether dietary creatine, administered alone or in the combination with other nutrients, can induce changes in the physical-chemical and microscopic characteristics of human semen.O... BackgroundNo studies have investigated whether dietary creatine, administered alone or in the combination with other nutrients, can induce changes in the physical-chemical and microscopic characteristics of human semen.ObjectivesThe primary objective of this randomized placebo-controlled exploratory pilot trial was to assess the effects of an 8-week supplementation regimen consisting of creatine, both with and without ubiquinol, on sperm quality in men classified as normospermic and oligospermic.MethodsA total of 15 volunteers (mean age 25.0 ± 6.1 years, body mass index 25.1 ± 2.0 kg/m²; including five oligospermic individuals) were randomly assigned, received the intended treatment, and were evaluated for spermiogram parameters, sperm biochemical markers, the World Health Organization (WHO-5) well-being index questionnaire, and the prevalence and severity of side effects.ResultsThere was a non-significant trend towards an increase in sperm concentration among participants receiving creatine-plus-ubiquinol, with an average rise of 7.4 million per milliliter ( = 0.22). Six out of ten participants receiving creatine (60%), both with and without ubiquinol, showed an improvement in sperm concentration at the 8-week follow-up, compared to only 20% of participants in the control group ( ≤ 0.05). In addition, all oligospermic men who received creatine and creatine-plus-ubiquinol demonstrated an improvement in sperm concentration at follow-up, whereas sperm concentration remained unchanged or further decreased among oligospermic men in the control group ( ≤ 0.05). Furthermore, there was a significant increase in sperm creatine concentration in the creatine-plus-ubiquinol group ( = 0.03), demonstrating an average rise of 125.4 µmol/L (35.8%) at the 8-week follow-up.ConclusionThese preliminary findings are of considerable interest for male fertility health; however, they require validation through well-designed longitudinal trials with larger sample sizes. The study is registered at ClinicalTrials.gov (NCT06202469).

A systematic review of the effectiveness of the health belief model-based nutrition education for dietary behavior change and chronic disease risk reduction.

Siyou SF

Nutr Health · 2026 Mar · PMID 41052053 · Publisher ↗

The health belief model (HBM) provides a theoretical framework to understand and predict health-related behaviors. Numerous studies have shown that HBM-based nutrition education programs are effective in inducing the ado... The health belief model (HBM) provides a theoretical framework to understand and predict health-related behaviors. Numerous studies have shown that HBM-based nutrition education programs are effective in inducing the adoption of healthy dietary behaviors, which is an effective way to prevent diet-related chronic diseases. However, little is known about reviews of existing findings pertaining to the HBM and nutrition education, aiming to highlight the need for a validated HBM-based practical tool that can be adapted and used by program managers or related specialists when developing, implementing, and evaluating nutrition education programs. This study aims to review the application of the HBM in nutrition education and highlight the need for an HBM-based practical tool that can be consistently used in nutrition education programs. We searched articles published between 2014 and 2025, which were related to the HBM and nutrition education, using Google Scholar, PubMed, EBSCO, and Taylor & Francis databases. Twelve articles were selected for this review after applying the inclusion and exclusion criteria. Across all the studies reviewed, HBM constructs were consistently shown to be significant predictors of positive dietary behavior changes ( < 0.05). All the articles reviewed indicated that the use of the HBM-based approach is an effective way to improve the effectiveness of nutrition education programs. The HBM can be used to assess and identify the HBM behavioral gaps of individuals, groups, or communities at the beginning of nutrition education programs, which can be subsequently addressed to induce the adoption of healthy dietary behaviors.

Cross-cultural comparison of factors influencing sustainable dietary behaviors among Japanese and German adults.

Kawasaki Y, Yoshii E, Fujisaki K … +5 more , Shimpo M, Nagao-Sato S, Boehnke J, Akamatsu R, Warschburger P

Nutr Health · 2025 Oct · PMID 41042985 · Publisher ↗

BackgroundThe concept of integrated sustainable dietary behaviors (SDBs) focuses on a series of dietary behaviors from food choice, storage and preservation, preparation (cooking), consumption, and disposal, as well as d... BackgroundThe concept of integrated sustainable dietary behaviors (SDBs) focuses on a series of dietary behaviors from food choice, storage and preservation, preparation (cooking), consumption, and disposal, as well as dietary patterns.ObjectivesThis study qualitatively describes the factors influencing the implementation of SDBs in Japanese and German adults and quantitatively compares the factors between the two cultures.MethodsThe online survey targeted 700 Japanese and 235 German adults, while the oral interview focused on 16 Japanese participants, recruited by a web-research company in 2021. Manifest content analysis, alongside chi-square and Fisher's exact tests, was used.ResultsThe participants' mean (SD) ages were 40.5 (10.9; Japanese; questionnaire), 26.2 (8.1; German; Questionnaire), and 38.1 (12.6; Japanese; interview), respectively. The 2515 codes (Japanese: 930; German: 1585) that emerged from the content analysis were divided into five main categories: (1) intrapersonal, (2) interpersonal, (3) food environment, (4) government, local governments, and research institutions, and (5) other. Compared to the Germans, the Japanese participants had a higher percentage of references to the intrapersonal" and government, local government, and research institution" categories. Japanese participants were more likely to cite psychological factors, portion size, and other factors, whereas German participants frequently referenced biology, skills of SDB, local access to sustainable food, and neighborhood characteristics.ConclusionCultural differences were found in the perceived factors for implementing SDBs. This study provides insight into the factors in implementing SDBs and can assist the development of promotion strategies that consider the cultural backgrounds of target populations.

Assessment of ultra-processed food consumption and pro-inflammatory dietary load in adults diagnosed with fibromyalgia syndrome: A case-control study.

Martín Pérez IM, Martín Pérez SE

Nutr Health · 2025 Sep · PMID 41021618 · Publisher ↗

Fibromyalgia syndrome (FMS) is a chronic condition marked by widespread musculoskeletal pain, persistent fatigue, and cognitive impairment. Its pathophysiology involves central sensitization, neuroinflammation, oxidative... Fibromyalgia syndrome (FMS) is a chronic condition marked by widespread musculoskeletal pain, persistent fatigue, and cognitive impairment. Its pathophysiology involves central sensitization, neuroinflammation, oxidative stress, and gut microbiota dysbiosis. Emerging evidence suggests that dietary factors-particularly the consumption of ultra-processed foods (UPFs)-may exacerbate these mechanisms and contribute to increased symptom burden. This study aimed to examine the dietary patterns, inflammatory potential of the diet, and body composition profiles in adults diagnosed with FMS compared to healthy controls. A case-control study was conducted with 89 adults (45 with FMS and 44 healthy controls). Dietary intake was assessed using a validated semi-quantitative Food Frequency Questionnaire. Food items were classified using the NOVA system, and the Dietary Inflammatory Index (DII) was calculated. Anthropometric data, body composition, and clinical variables-including pain intensity (Visual Analog Scale, VAS), fatigue (Fatigue Severity Scale, FSS), and Fibromyalgia Impact Questionnaire (FIQ)-were recorded. Statistical analyses included t-tests and Mann-Whitney U tests (significance set at  < 0.05). Patients with FMS consumed significantly more UPFs (34.5 ± 8.9% vs. 26.7 ± 7.1% of total energy intake;  < 0.001) and had higher DII scores (45.3 ± 8.7 vs. 35.1 ± 9.2;  < 0.001). The FMS group exhibited higher body mass index (27.5 ± 4.2 vs. 24.9 ± 3.8 kg/m²;  = 0.014), increased fat mass (34.5 ± 5.3% vs. 28.1 ± 4.7%;  = 0.011), and lower muscle mass (47.5 ± 4.8% vs. 49.3 ± 4.2%;  = 0.019). Clinically, they reported greater pain (VAS: 6.8 ± 1.9 vs. 1.2 ± 0.5;  < 0.001) and fatigue (FSS: 5.1 ± 1.1 vs. 2.4 ± 0.7;  < 0.001), with significant impairments in FIQ scores. Nutritional analysis showed lower intakes of magnesium, vitamin C, and polyphenols, and higher consumption of saturated fats and refined carbohydrates. Adults with FMS display a pro-inflammatory dietary profile characterized by high UPF consumption and reduced intake of protective nutrients. These patterns are associated with worsened symptomatology and adverse body composition, underscoring the potential role of anti-inflammatory dietary strategies in multidisciplinary FMS management.

The effect of nutrition education on premenstrual syndrome: Randomized controlled study.

Mataracı-Değirmenci D, Erbil N

Nutr Health · 2025 Sep · PMID 41004653 · Publisher ↗

BackgroundPremenstrual syndrome (PMS) is a prevalent condition that impairs quality of life and daily functioning in young women, particularly university students.ObjectivesThis study aimed to evaluate the effect of targ... BackgroundPremenstrual syndrome (PMS) is a prevalent condition that impairs quality of life and daily functioning in young women, particularly university students.ObjectivesThis study aimed to evaluate the effect of targeted nutrition education on PMS severity, nutrient intake, and anthropometric measures.MethodsEighty-three nursing students diagnosed with PMS (PMSS ≥111) were randomized into intervention ( = 43) and control ( = 40) groups. The intervention group received a 1-h nutrition education session, supported by follow-up emails at 30 and 60 days. PMS severity, dietary intake, and anthropometric data were collected at baseline and 4 months post-intervention.ResultsNutrition education led to significant improvements in the intervention group. PMSS total scores decreased by 27.5 points ( < 0.05), with notable reductions across subscales such as depressive feelings, anxiety, irritability, depressive thoughts, appetite changes, and sleep disturbances. Concurrently, body weight (-1.2 kg;  < 0.05), BMI (-0.5 kg/m;  < 0.05), waist circumference (-2.1 cm;  < 0.05), and hip circumference (-1.5 cm;  < 0.05) significantly declined. Nutrient intake improved significantly, with increases in protein (+11.4 g/day), vitamin B2 (+0.3 mg/day), calcium (+184.3 mg/day), iron (+1.1 mg/day), and zinc (+0.6 mg/day) ( < 0.05). No significant changes were observed in the control group.ConclusionsEven a short-duration nutrition education intervention can substantially reduce PMS severity, improve dietary habits, and promote healthier body composition. These findings support incorporating nutrition counseling into PMS management as an effective, low-cost, non-pharmacological intervention.
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