Journal Of The American Academy Of Dermatology[JOURNAL]

Sun 200 papers

Comparison of Natural Language Processing versus International Classification of Diseases Coding for Skin Cancer Subtype Identification from Pathology Reports.

Chavooshi M, Garcia N, Apicella M … +8 more , Nyamongo N, Jain A, Seelig C, Perez-Stable C, Razjouyan J, Helmer DA, Hastings KT, Varra V

J Am Acad Dermatol · 2026 Jun · PMID 42323018 · Publisher ↗

Abstract loading — click title to view on PubMed.

Get PDF PubMed ↗

Re: "The effect of isotretinoin treatment for acne vulgaris on height in adolescents: A retrospective cohort study using the Rochester Epidemiology Project.".

Mao G, Lan H

J Am Acad Dermatol · 2026 Jun · PMID 42323017 · Publisher ↗

Abstract loading — click title to view on PubMed.

Get PDF PubMed ↗

Granuloma Annulare: An Updated Review of Epidemiology, Molecular Pathogenesis, and Management.

Foroohar T, Berk-Krauss J, Caplan AS … +9 more , Leung TH, Barbieri JS, Wanat KA, Nelson C, Mangold AR, English JC, Rosenbach M, Shields BE, Damsky W

J Am Acad Dermatol · 2026 Jun · PMID 42320859 · Publisher ↗

Granuloma annulare (GA) is an inflammatory skin disease typically characterized by an erythematous eruption consisting of papules and annular plaques. GA can have a severe impact on quality of life, especially when wides... Granuloma annulare (GA) is an inflammatory skin disease typically characterized by an erythematous eruption consisting of papules and annular plaques. GA can have a severe impact on quality of life, especially when widespread. GA can be difficult to treat and often recurs after treatment is stopped; there remain no FDA-approved therapies. In recent years, there has been significant progress in understanding the epidemiology, disease associations, and molecular pathogenesis of GA. Patients with GA are more likely to have hyperlipidemia, diabetes mellitus, and autoimmune diseases including thyroiditis, rheumatoid arthritis, and systemic lupus erythematosus. These associations further underscore the importance of recognizing GA and evaluating for comorbid disease. Accurate diagnosis of GA requires distinguishing it from its clinical and histologic mimics, some of which share annular morphology or granulomatous inflammation. Molecular work has suggested a T-cell mediated pathogenesis and identified key cytokines and other signals that drive macrophage accumulation and activation in tissue. Emerging therapies that block these cytokine signals are showing promise in the clinic. In this article, we provide an updated overview of the epidemiology, disease associations, clinical and histopathologic characteristics, molecular pathogenesis, and treatment of GA.

Get PDF PubMed ↗

Cutaneous Vasculopathy in Autoimmune Connective Tissue Diseases - Need for a Standardized Evaluation tool.

Subhadarshani S, Bishnoi A, Conticini E … +4 more , Elman S, Aggarwal R, Shaw K, Khanna U

J Am Acad Dermatol · 2026 Jun · PMID 42320858 · Publisher ↗

Abstract loading — click title to view on PubMed.

Get PDF PubMed ↗

Free Sunscreen Dispensers in Colorado State Parks: Insights from Park Ranger Management.

Hanigan M, Abdulkader F, Case N … +2 more , Walker B, Newman S

J Am Acad Dermatol · 2026 Jun · PMID 42320857 · Publisher ↗

Abstract loading — click title to view on PubMed.

Get PDF PubMed ↗

Outcomes of dermatologist-performed skin cancer screening in an academic setting: a retrospective cohort study.

Burke OM, Hartoya M, Barbato K … +5 more , Sherfield J, Huang J, Abdshah A, Hu S, Maderal A

J Am Acad Dermatol · 2026 Jun · PMID 42320856 · Publisher ↗

BACKGROUND: Early detection of skin cancer improves outcomes, but the utility of dermatologist-performed total body skin examinations(TBSEs) in unselected populations remains uncertain. OBJECTIVE: To evaluate the diagnos... BACKGROUND: Early detection of skin cancer improves outcomes, but the utility of dermatologist-performed total body skin examinations(TBSEs) in unselected populations remains uncertain. OBJECTIVE: To evaluate the diagnostic yield, biopsy burden, and temporal trends of dermatologist-led TBSEs in an academic screening program. METHODS: This retrospective cohort included 3,127 encounters from 1,572 University of Miami employees and spouses who underwent annual TBSEs between January 2019-June 2024. Primary outcomes were detection of premalignant(actinic keratoses) and malignant lesions (basal cell carcinoma[BCC], squamous cell carcinoma[SCC], melanoma). Secondary outcomes included number needed to biopsy(NNB), predictive value of patient-reported lesions, and changes across screening rounds. RESULTS: Across TBSEs, premalignant, in-situ, and malignant lesions were detected in 11.0%, 0.22%, and 2.6% of exams. Of the screenings with malignant findings, 69 found BCC while 12 found SCC. Detection was highest among older adults and those with prior nonmelanoma skin cancer. Patient-reported "spots of concern" had low predictive value (PPV 2.7% for premalignant, 0.5% for in-situ, 1.2% for malignant). Overall NNB was 4.83, improving from 6.10 to 2.79 across rounds. LIMITATIONS: Participation was voluntary, introducing selection bias; biopsy practices varied, and external procedures may have been missed. CONCLUSIONS: Dermatologist-performed TBSEs identified early-stage skin cancers, with higher yield in higher-risk groups.

Get PDF PubMed ↗

Cobratide injection vs Pregabalin for Moderate-to-Severe Acute Herpes Zoster Neuralgia: A Randomized, Double-Blind, Double-Dummy, Active-Controlled, Multicenter Exploratory Trial.

Xu X, Han X, Li X … +9 more , Chen L, Li C, Ma L, Ji M, Zhang Y, Chen H, Wang X, Wang Q, Gao X

J Am Acad Dermatol · 2026 Jun · PMID 42320855 · Publisher ↗

BACKGROUND: Acute herpes zoster (HZ) neuralgia impairs quality of life and may progress to postherpetic neuralgia (PHN). Existing analgesics are often limited by adverse effects in older adults. OBJECTIVE: To evaluate Co... BACKGROUND: Acute herpes zoster (HZ) neuralgia impairs quality of life and may progress to postherpetic neuralgia (PHN). Existing analgesics are often limited by adverse effects in older adults. OBJECTIVE: To evaluate Cobratide injection for moderate-to-severe acute HZ neuralgia and explore its potential effect on PHN incidence. METHODS: In this multicenter, randomized, double-blind, double-dummy, active-controlled exploratory trial, 80 patients aged 50 to 70 years were assigned 1:1 to intramuscular Cobratide injection or oral Pregabalin for 28 days. The primary endpoint was change in average Numeric Rating Scale (NRS) pain score from baseline to day 28. No formal power calculation was performed. RESULTS: At day 28, least-squares mean NRS reductions were 6.00 with Cobratide injection and 5.63 with Pregabalin (between-group difference, 0.37; P=.186). At week 12, PHN occurred in 0/27 and 3/27 evaluable patients, respectively (P=.236). Treatment-emergent adverse events occurred in 35.9% and 51.2% of patients, respectively. LIMITATIONS: Exploratory design, small sample size, and lack of systematic collection of zoster vaccination history and rash-onset timing limited inference. CONCLUSIONS: Cobratide injection showed a similar magnitude of pain reduction to Pregabalin, with a favorable tolerability signal. Larger adequately powered trials are needed.

Get PDF PubMed ↗