J Obstet Gynaecol India
· 2026 Apr · PMID 42145931
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BACKGROUND: To determine the relation between acute phase reactant like CRP inthe first trimester as a screening test for gestational diabetes mellitus. METHODS: A prospective observational study was conducted between De...BACKGROUND: To determine the relation between acute phase reactant like CRP inthe first trimester as a screening test for gestational diabetes mellitus. METHODS: A prospective observational study was conducted between December 2020 to August 2022, which included healthy pregnant women who visited Lady Goschen hospital and Kasturba Medical college Attavar, Mangalore for their antenatal. Check-ups and counselling After obtaining informed consent, a detailed history and a physical examination was done to rule out all possible causes of the elevated CRP levels levels were measured by HS ELISA,and they were screened for gestational diabetes mellitus at 24-28 weeks. Association was tested between CRP positive patients and patients diagnosed with Gestational Diabetes Mellitus. RESULTS: Out of 196 patients included in the study,55(27.3%) patients were diagnosed with GDM.Out of 55 patients,14 was found to be CRP positive. value was. Found to be 0.000 which was statistically significant. CONCLUSION: In this study association was found between inflammation in first trimester which was detected by rise in the CRP and subsequent risk of development of GDM. It could be a useful test for prediction of GDM. Specificity was found to be higher but sensitivity was found to be low, hence it may not be an ideal screening test.
J Obstet Gynaecol India
· 2026 Apr · PMID 42145930
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INTRODUCTION: Embryo transfer is the most crucial and final step in IVF cycle, accounting for about 30% failures in case of improper technique. Therefore, a new concept of evaluating uterine receptivity by M. Applebaum w...INTRODUCTION: Embryo transfer is the most crucial and final step in IVF cycle, accounting for about 30% failures in case of improper technique. Therefore, a new concept of evaluating uterine receptivity by M. Applebaum was developed that has shown promising results to predict IVF outcome. AIM AND OBJECTIVES: To evaluate uterine receptivity by using Applebaum scoring system and correlate the parameters with pregnancy outcomes among infertile patients undergoing embryo transfer in a tertiary care hospital in North India. MATERIAL AND METHODS: This was a prospective interventional study, conducted in Department of Obstetrics and Gynecology at SRMSIMS, Bareilly on 60 patients who presented with infertility during the period from July 2023 to September 2023. To assess uterine receptivity, ultrasonographic and Doppler parameters were analyzed and scored as per parameters of Applebaum uterine scoring system and serum beta-human chorionic gonadotropin was performed 14 days after ET to confirm the pregnancy. OBSERVATIONS: The mean age and BMI among the females who conceived was 34.78 ± 6.28 years and 23.7 ± 2.17 kg/m2respectively, majority of whom had marriage duration of 4-6 years. Pulsatility Index, myometrial contraction, and total Applebaum uterine score parameters were significantly (p 0.05) higher among patients with pregnancy than without pregnancy. CONCLUSION: The endometrial receptivity is predeterminant in predicting the pregnancy outcome. Uterine scoring system will help to perform embryo transfers in only favourable uterine environment.
Bandlish S, Mehra R, Goel P
… +2 more, Kaur J, Gupta S
J Obstet Gynaecol India
· 2026 Apr · PMID 42145929
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BACKGROUND: Preeclampsia is a multifactorial disorder of hypertension in pregnancy which contributes majorly to maternal and perinatal morbidity and mortality. PLGF (placental growth factor) and sFlt-1(soluble fms-like t...BACKGROUND: Preeclampsia is a multifactorial disorder of hypertension in pregnancy which contributes majorly to maternal and perinatal morbidity and mortality. PLGF (placental growth factor) and sFlt-1(soluble fms-like tyrosine kinase) are measurable biomolecules which can be used as biomarkers. This study estimated the levels of PLGF and sFlt-1 in patients of preeclampsiaeclampsia syndrome and correlated them with disease severity and prognosis. METHODS: A longitudinal observational study was conducted enrolling 125 women with preeclampsiaeclampsia syndrome and levels of PLGF, sFlt-1 and their ratio were correlated with disease severity and prognosis. RESULTS: The levels of serum biomarkers in the patients of preeclampsia were compared with patients of preeclampsia with severe features and eclampsia and no significant correlation was found. The patients with preeclampsia had a median value of sFlt-1 and ratio sFlt-1/PLGF as 24.50 ng/ml, and 13.50, respectively, whereas patients in the severe group had a median value of sFlt-1 as 28.00 ng/ml and ratio sFlt-1/PLGF as 14.00, respectively ( values 0.340 and 0.815, respectively). Patients with preeclampsia had PLGF in range of 938-13,317 pg/ml versus 1192.50-2708.75 pg/ml in those with severe disease ( value 0.610). CONCLUSION: Although serum sFlt-1 was higher, serum PLGF was lower and the ratio of sFlt-1/PLGF was higher in patients with severe preeclampsia in comparison with non-severe cases, the difference was not statistically significant.
J Obstet Gynaecol India
· 2026 Apr · PMID 42145928
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BACKGROUND: Periodontal disease is a highly prevalent inflammatory condition that tends to worsen during pregnancy due to hormonal, vascular, and immune changes. Emerging data suggests that poor maternal periodontal heal...BACKGROUND: Periodontal disease is a highly prevalent inflammatory condition that tends to worsen during pregnancy due to hormonal, vascular, and immune changes. Emerging data suggests that poor maternal periodontal health may influence pregnancy outcomes, yet it often remains overlooked and uncared in routine antenatal care. OBJECTIVES: This review was written to summarize the global and Indian burden of periodontal disease in pregnancy, explain its biological mechanisms, and evaluate its association with adverse perinatal outcomes, along with available preventive and treatment strategies. METHODS: A targeted search of PubMed, Google Scholar, and Embase (2015 onwards) was conducted. Of 206 articles screened, 44 met eligibility criteria and were included. Studies describing epidemiology, pathophysiology, diagnostic features, maternal-foetal effects, and treatment outcomes were reviewed. Select earlier studies were added for diagnostic and therapeutic clarity. RESULTS: Globally, pregnancy-related gingivitis affects majority of women, with periodontitis prevalence varying widely across regions, including India. Periodontal inflammation may elevate systemic cytokines and bacterial endotoxins, contributing to preeclampsia, gestational diabetes, preterm birth, low birth weight, and foetal growth restriction. Non-surgical periodontal therapy in the second trimester is safe and may modestly reduce preterm birth and low birth weight, though findings vary across studies. CONCLUSION: Maternal periodontal disease is a modifiable risk factor with important implications for pregnancy outcomes. Integrating oral health screening, counselling, and timely periodontal care into antenatal services could support healthier maternal and neonatal outcomes. Further well-designed trials are needed to define the magnitude of benefit from treatment.
Ozdemir CY, Cicekli N, Coşkun H
… +4 more, Dur R, Demir I, Sezer NÇ, Arioz DT
J Obstet Gynaecol India
· 2026 Apr · PMID 42145926
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AIM: We aimed to compare overall survival (OS) and progression-free survival (PFS) between patients treated with laparoscopy and laparotomy for endometrioid endometrial cancer (EEC) with cervical involvement. METHODS: A...AIM: We aimed to compare overall survival (OS) and progression-free survival (PFS) between patients treated with laparoscopy and laparotomy for endometrioid endometrial cancer (EEC) with cervical involvement. METHODS: A total of 41 patients with EEC with cervical involvement were included in the study. The exclusion criteria were non-endometriod type endometrial cancer in the postoperative pathology report results, synchronous tumor or stage I endometrial cancer. Additionally, stage III and stage IV patients without cervical involvement were excluded. Participants were categorized into two groups, namely group 1 (21 patients who underwent laparotomy) and group 2 (20 patients who underwent laparoscopic surgery). RESULTS: 5-year OS of EEC with cervical involvement was 61%, 52.4% in group 1 and 70% in group 2 ( = 0.417). Recurrence was detected in 7 patients. 5-year PFS of EEC with cervical involvement was 82.9%, 85.7% in group 1 and 80% in group 2 ( = 0.704). No significant difference was detected in terms of recurrence between the two groups ( = 0.840). CONCLUSION: EEC represents the most common endometrial cancer subgroup and has a favorable prognosis. In this study, although our patient number was small, we compared laparoscopy and laparotomy in the treatment of EEC with cervical involvement and no statistical difference was found.
Desai GS, Kukral P, Panchal V
… +1 more, Deshmukh S
J Obstet Gynaecol India
· 2026 Apr · PMID 42145925
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BACKGROUND: Large uteri with multiple fibroids or adenomyosis present significant challenges for minimally invasive surgery due to increased vascularity, distorted pelvic anatomy, and limited working space. While robotic...BACKGROUND: Large uteri with multiple fibroids or adenomyosis present significant challenges for minimally invasive surgery due to increased vascularity, distorted pelvic anatomy, and limited working space. While robotic platforms enhance precision through improved dexterity and vision, most surgeons still rely on an additional assistant port for suction, traction, and suture introduction. Reduced-port robotic hysterectomy aims to minimise abdominal incisions without compromising safety. Evidence for assistant-port-free approaches in complex pathology remains scarce. AIMS: To describe the feasibility, safety, and technical nuances of a three-port, assistant-port-free robotic total hysterectomy with bilateral salpingo-oophorectomy for a large adenomyotic uterus with multiple fibroids using the da Vinci Xi robotic surgical system. MATERIALS AND METHODS: A 58-year-old woman presented with post-menopausal bleeding and imaging revealing diffuse adenomyosis with multiple large fibroids. A three-port robotic approach was performed without an accessory port. A V-type uterine manipulator was used. Key operative strategies included precise port spacing, early bilateral devascularisation, retrograde dissection of obscured vascular pedicles, and colpotomy-based suture introduction for vault closure. Outcomes assessed included operative time, blood loss, complications, and recovery. CONCLUSION: Assistant-port-free three-port robotic hysterectomy is feasible and safe for large benign uteri in experienced hands. Strategic port positioning, effective uterine manipulation, meticulous vascular control, and innovative colpotomy-assisted vault suturing enable elimination of the assistant port without compromising operative efficiency or safety. This technique may reduce abdominal morbidity and resource utilisation while preserving the ergonomic and precision advantages of robotic surgery. Further studies with larger cohorts are warranted to validate reproducibility and long-term outcomes.
J Obstet Gynaecol India
· 2026 Apr · PMID 42145924
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A 60-year-old obese woman presented with severe vaginal pain and a large mass. Manual extraction revealed a copper IUD embedded in a 40 g calculus. This rare case highlights the importance of regular gynecologic care for...A 60-year-old obese woman presented with severe vaginal pain and a large mass. Manual extraction revealed a copper IUD embedded in a 40 g calculus. This rare case highlights the importance of regular gynecologic care for all women, prompt IUD removal, and proper management to prevent complications.
J Obstet Gynaecol India
· 2026 Apr · PMID 42145923
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BACKGROUND: Gynaecological robotic surgery is one of the latest transformations in minimally invasive operative techniques. Gynaecological surgeons treat several conditions that affect a woman's reproductive organs using...BACKGROUND: Gynaecological robotic surgery is one of the latest transformations in minimally invasive operative techniques. Gynaecological surgeons treat several conditions that affect a woman's reproductive organs using miniature instruments guided through a robotic system. Currently, benign gynaecological surgeries do not have many remarkable advantages over conventional laparoscopic surgeries. EndoWrist manoeuvres of robotic instruments resemble the open surgical technique, which allows better and precise suturing than conventional laparoscopy in procedures like myomectomy and sacrocolpopexies. Our study showcases our adaptation to the newest innovation and its outcome. METHODOLOGY: Our prospective study includes 30 benign gynaecological cases operated by single surgeon in Da Vinci Xi system from June 2023 to July 2024. This included 28 hysterectomies and 2 myomectomies. Baseline demographic data, docking time, console time, blood loss, post-operative pain and dosage of analgesia taken, post-op ambulation, length of hospital stay, and post-op complications have been assessed. RESULTS: The BMI of 30-34.9 kg/m contributed to 24%, and 35-39.9 kg/m contributed to 21%. Docking time reduced from around 45 ± 15 min to 15 ± 5 min. An average console time was 132 min, which stepped down from 216 min. The average blood loss in 50% of them is 50-100 ml. A 95% of patients were discharged between 3 and 5 days. Post-operatively, 35% had mild pain and 50% moderate pain, assessed by the VAS scale. CONCLUSION: A minimally invasive technique with outcomes similar to laparoscopy but with an EndoWrist movement aiding to a less steeper learning curve to the surgeons and patient friendly outcomes which enhance with expertise.
Golshahi F, Sahebdel B, Saedi N
… +2 more, Moradi Z, Parsaei M
J Obstet Gynaecol India
· 2026 Apr · PMID 42145922
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Parvovirus B19 infection during pregnancy can result in vertical transmission in 17-33% of cases, potentially leading to severe complications such as fetal anemia or hydrops fetalis. Although intrauterine transfusion can...Parvovirus B19 infection during pregnancy can result in vertical transmission in 17-33% of cases, potentially leading to severe complications such as fetal anemia or hydrops fetalis. Although intrauterine transfusion can improve survival in severe cases, delayed diagnosis often results in fetal loss. Due to nonspecific symptoms, missed diagnoses are likely underreported. This editorial strongly advocates for a broader assessment of all mothers presenting with flu-like symptoms, recent exposure to infected individuals, or suspicious ultrasound findings to facilitate earlier detection. Proactive maternal screening is crucial to improving outcomes and reducing fetal mortality associated with parvovirus B19 infection.
Agrawal S, Gupta V, Sharma A
… +3 more, Choudhary A, Thakur B, Thakker M
J Obstet Gynaecol India
· 2026 Apr · PMID 42145921
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BACKGROUND: Placenta accreta spectrum (PAS) is a major cause of pregnancy-related mortality and morbidity in developed countries. To diagnose placenta accreta, high diagnostic consideration and good radiological examinat...BACKGROUND: Placenta accreta spectrum (PAS) is a major cause of pregnancy-related mortality and morbidity in developed countries. To diagnose placenta accreta, high diagnostic consideration and good radiological examination is crucial. Intraoperative finding and histopathological examination confirm the diagnosis made clinically. So we have conducted the present study aiming to do correlation of clinical and radiological findings and histological examination of peripartum hysterectomy specimen of PAS patients. METHODOLOGY: It is ambispective observational study, done at our institute from January 2021 to December 2024, after ethical clearance. All patients of suspected PAS who were managed surgically with hysterectomy are included. Data collected and correlated with clinical and radiological and histopathological reports. RESULTS: Data were collected and analysed for 43 women. All 43 women have h/o scarred uterus with placenta previa, intraoperatively positive finding was found in more than 80% of women (large vessels at lower segment-86%, bulge at lower segment-72%, bladder invasion-12%, broad ligament invasion-5%). Ultrasonography (USG) diagnosed or suspected PAS in 79%, in 21% women, PAS was ruled out by USG (false negative). Magnetic resonance imaging (MRI) report was s/o PAS in 100% women (True Positive). All 43 women were diagnosed with adhered placenta histopathologically, in 34 women Placenta accreta (79%), 5 Placenta increta (12%), and 4 women Placenta percreta (9%) was detected. CONCLUSION: Any pregnant women with history of scarred uterus or previous caesarean section (LSCS) and placenta previa should be evaluated for PAS by USG and MRI and should be managed in tertiary centre. Also the degree of invasion can vary and may be missed in imaging. So intraoperative finding and histopathological examination are critical for final diagnosis.
Manivel R, Vickram AS, Sharma N
… +1 more, Sivanantham S
J Obstet Gynaecol India
· 2026 Apr · PMID 42145920
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BACKGROUND: Male infertility, often worsened by oxidative stress, remains a challenging issue that significantly impacts sperm quality. OBJECTIVES: Reactive oxygen species (ROS) are key contributors to sperm DNA damage,...BACKGROUND: Male infertility, often worsened by oxidative stress, remains a challenging issue that significantly impacts sperm quality. OBJECTIVES: Reactive oxygen species (ROS) are key contributors to sperm DNA damage, reduced motility, and abnormal morphology. In response to these challenges, advanced sperm processing techniques like density gradient centrifugation and magnetic-activated sperm cell sorting have been developed to optimize sperm selection and reduce ROS levels. CONCLUSION: This commentary examines recent research on these techniques and their impact on sperm quality, highlighting their potential in the treatment of male infertility.
Das P, Kahlon N, Sharma P
… +3 more, Pandey AK, Das A, Deepak KK
J Obstet Gynaecol India
· 2026 Feb · PMID 41970449
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INTRODUCTION: Preeclampsia (PE) is a hypertensive disorder of pregnancy associated with endothelial dysfunction and neurological complications such as posterior reversible encephalopathy syndrome (PRES). Conventional lab...INTRODUCTION: Preeclampsia (PE) is a hypertensive disorder of pregnancy associated with endothelial dysfunction and neurological complications such as posterior reversible encephalopathy syndrome (PRES). Conventional laboratory tests do not adequately capture cerebral involvement. Transcranial Doppler (TCD) offers a non-invasive method to assess cerebral hemodynamics. This study aimed to characterize cerebral flow dynamics in Indian women with PE. METHODS: A cross-sectional observational study was conducted including 44 pregnant women (25 with PE, 19 normotensives). PE was diagnosed using ISSHP criteria. TCD insonation of middle, anterior, and posterior cerebral arteries was performed with a 2 MHz probe via transtemporal windows. Parameters measured were peak systolic velocity (PSV), end-diastolic velocity (EDV), cerebral perfusion pressure (CPP), and resistance-area product (RAP). Data were analyzed using SPSS v20.0 with Student's t-test and Kruskal-Wallis tests. RESULTS: PE participants demonstrated significantly higher systolic, diastolic, and mean arterial pressures (p 0.001). TCD revealed increased PSV in bilateral MCA, reduced EDV, and elevated CPP across MCA, ACA, and PCA compared to controls. RAP was markedly raised in the PCA, suggesting impaired autoregulation and posterior circulation vulnerability to hyperperfusion. DISCUSSION: The study revealed significantly elevated peak systolic velocities (PSV), raised cerebral perfusion pressures (CPP) in the middle and posterior cerebral arteries (MCA and PCA) of preeclamptics, with concurrent reductions in end-diastolic velocity (EDV). Resistance Area Product (RAP) was increased in the PCA, suggesting impaired autoregulation and increased susceptibility to hyperperfusionrelated injury. These hemodynamic disturbances, particularly in the posterior circulation, may serve as early indicators of PRES risk. TCD provides a feasible bedside tool for antenatal neurovascular risk stratification. Larger, multicenter studies are warranted to establish predictive thresholds for clinical use.
J Obstet Gynaecol India
· 2026 Feb · PMID 41970448
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Minimal access surgery (MAS) represents the third major revolution in surgical practice after anaesthesia and antisepsis. Despite its widespread adoption, structured training in MAS has lagged behind, often leaving postg...Minimal access surgery (MAS) represents the third major revolution in surgical practice after anaesthesia and antisepsis. Despite its widespread adoption, structured training in MAS has lagged behind, often leaving postgraduate curriculum incomplete. This manuscript explores the evolution of MAS training, highlighting the unique challenges of eye-hand coordination, depth perception, and reliance on camera system. Various training modalities including endotrainers, animal and cadaveric models, simulators, observer ships, and credentialing programmes are critically examined. The emergence of robotic surgery introduces new skill sets and assessment tools, necessitating comprehensive curriculum that integrate simulation, team coordination, and structured certification. Future horizons point towards affordable robotic systems, virtual reality, and AI-powered feedback, making training more realistic and accessible. A structured, credentialed approach remains essential to ensure safe surgical practice and optimal patient outcome.
Mehrotra L, Sodha KB, Firdos H
… +1 more, Mehrotra M
J Obstet Gynaecol India
· 2026 Feb · PMID 41970446
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BACKGROUND: Robotic assisted surgery has attained widespread acceptance in the past two decades as the robotic platform provides 3D vision, tremor filtration and increased dexterity with upto 7 degrees of freedom. This o...BACKGROUND: Robotic assisted surgery has attained widespread acceptance in the past two decades as the robotic platform provides 3D vision, tremor filtration and increased dexterity with upto 7 degrees of freedom. This original article is dedicated to providing an impartial assessment of robotic technology, elucidating our insights gained from 72 gynaecological surgeries conducted with a novel modular robotic system in a tertiary care hospital. METHODS: A meticulous examination of 72 robotic benign gynaecological surgeries was undertaken, wherein average operative time, estimated blood loss, postoperative hospital stay, intraoperative and postoperative complications, and conversion rates were subjected to retrospective scrutiny. RESULTS: A wide spectrum of benign gynecological pathologies could be dealt with using the robotic platform with acceptable operative time, blood loss and post operative complications. The average operative time for our first 25 cases was compared with the subsequent 47 cases, this difference was not found to be statistically significant ( value = 0.28) suggesting that there does not appear to be a significant learning curve for a trained laparoscopic gynecologist in transitioning to robotic gynecological surgeries. CONCLUSIONS: Robotic benign gynecological surgery is feasible and safe. The novel modular robotic platform gives the advantages of an open surgeon's console, enhanced degrees of freedom of movement of instruments and stability. Robotic benign gynecological surgery appears to offer reasonable post operative recovery with acceptable intra and post operative complication profile.
J Obstet Gynaecol India
· 2026 Feb · PMID 41970445
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Innovations in the health care system are drivers to carry it forward. With Artificial Intelligence, personalized medicine, digital health and remote monitoring, it is advancing at faster pace. Advances are the way forwa...Innovations in the health care system are drivers to carry it forward. With Artificial Intelligence, personalized medicine, digital health and remote monitoring, it is advancing at faster pace. Advances are the way forward, reshaping the module of practitioners and patients. Landscape of Obstetrics & Gynaecology has transformed from pelvic examinations, paper charts, USG machines in clinic to digital tools that can increase patient care, improve diagnostic accuracy and streamline clinical workflow. Modern technologies complement traditional clinical skill while addressing women's health issues. The present-day clinician will be able to integrate technology with clinical touch in the best interest of the patient. Clinicians can take a lead in innovations rather than just being care givers. Research environment, dedicated funds, platform to showcase new ideas can go long way for health care advances.
Bhatia K, Mehrotra S, Solanki V
… +4 more, Parihar A, Agrawal M, Jaiswar SP, Khanna V
J Obstet Gynaecol India
· 2026 Feb · PMID 41970443
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PURPOSE: Purpose of study-Pre-eclampsia is a leading cause of maternal mortality, with 12% of deaths being attributed to this condition and its complications.The neurological sequelae of pre-eclampsia are related to cere...PURPOSE: Purpose of study-Pre-eclampsia is a leading cause of maternal mortality, with 12% of deaths being attributed to this condition and its complications.The neurological sequelae of pre-eclampsia are related to cerebrovascular endothelial dysfunction. Ocular circulation reflects the status of cerebral circulation as the ophthalmic artery has embryological, anatomic and functional similarities to CNS arteriolar vessels. OBJECTIVE: To evaluate the changes in ophthalmic artery Doppler parameter, Peak ratio in women with pre-eclampsia as compared to normotensive women and to examine its association with pregnancy outcome in pre eclamptic women. METHODS: This was a prospective cohort study conducted at a tertiary care center, over a period of one year involving preeclamptic and normotensive women. Opthalmic artery Doppler was performed in all recruited women. All pre-eclamptic women were followed till discharge for maternal and fetal outcomes. RESULT: 222 women were recruited out of which 111 were pre eclamptic and 111 were normotensive. Peak ratio cut off was calculated as 0.85 by plotting a receiver operator curve. 88.1% of pre eclamptic women with higher peak ratio i.e. > 0.85 had adverse maternal outcomes whereas 51.9% pre-eclamptic women with peak ratio < 0.815 had adverse outcomes. CONCLUSION: Ophthalmic artery Doppler could serve as a cost effective, non invasive readily applicable and reproducible marker to predict adverse maternal outcome in pre eclamptic women,thus identifying risk for neurological complications in pre eclamptic women, thereby allowing for appropriate targeted therapy.
Chugh M, Goel B, Sehgal A
… +3 more, Dubey S, Handa U, Walia D
J Obstet Gynaecol India
· 2026 Feb · PMID 41970442
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BACKGROUND: Cervical cancer remains a leading cause of mortality for women in low-income countries. Therefore, there is an urgent need for a point-of-care cervical cancer screening test for community-based settings that...BACKGROUND: Cervical cancer remains a leading cause of mortality for women in low-income countries. Therefore, there is an urgent need for a point-of-care cervical cancer screening test for community-based settings that can be used for triaging and managing women with preinvasive and early invasive lesions of cervix. METHOD: A cross-sectional study was conducted to evaluate the diagnostic accuracy of an indigenous artificial intelligence (AI)-enabled trans-vaginal colposcopic device called Smart Scope®. Parallel screening with cervical cytology and assessment of magnified digital images was done by a trained observer to minimize false negatives. Cervical biopsy was taken for any abnormality identified on any of the three tests. Histopathology report of the biopsy was taken as the reference standard. RESULT: A total of 268 women were recruited for the study. Cervical evaluation with the Smart Scope® identified 17.5% ( = 47) cervices with pre-cancerous/cancerous lesions, 19.4% ( = 52) with high-risk lesions, 14.2% ( = 38) with inflammatory/benign lesions and 48.9% ( = 131) cervices as normal. Taking cervical biopsy as the reference standard, sensitivity, specificity, PPV and NPV were 68.4%, 65.5%, 13.1%, and 96.4% respectively. In comparison, the sensitivity, specificity, PPV and NPV of cervical cytology were 43.8%, 93.3%, 46.7%, and 92.5% respectively, while that of assessment of magnified digital images by trained observer was 89.5%, 49.1%, 22.4%, and 96.6% respectively. CONCLUSION: Smart Scope®-based evaluation in conjunction with the assessment of magnified digital images by a trained observer can be an effective tool for cervical cancer screening. Further improvement of AI-based diagnosis can make it an effective tool for community-based screening.