Lechien JR, Maniaci A, Salzano G
… +6 more, Chiesa-Estomba CM, Mayo-Yanez M, Saibene A, Iannella G, Saussez S, Vaira LA
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Mar · PMID 41791931
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OBJECTIVES: To evaluate the patient perception and awareness of psychophysical olfactory testing (PT). METHODS: A survey was distributed to 119 consecutive patients consulting in the Dour Medical Center for olfactory dys...OBJECTIVES: To evaluate the patient perception and awareness of psychophysical olfactory testing (PT). METHODS: A survey was distributed to 119 consecutive patients consulting in the Dour Medical Center for olfactory dysfunction (OD) lasting for more than 6months. The survey assessed the patient opinion regarding the usefulness, advantages, and impact of PT on the olfactory check-up and follow-up. Smell sense was evaluated with threshold, discrimination and identification (TDI) test, and the Olfactory Disorder Questionnaire (ODQ). RESULTS: Survey was completed by 118 patients (99%). There were 72 females (61%). The mean age was 55.1±15.1years. There were 53 (45.0%) patients with complete smell loss, 43 (36.4%) with partial smell loss, and 22 (18.6%) with disturbed smell (parosmia). The mean TDI was 18.0±10.9. The mean ODQ was 35.8±13.9. PT are considered a supportive test for the evaluation of the OD by 66% of patients. The primary PT limitations were considered as the presence of uncommon (65.3%) or unknown odors (42.7%), and the lack of consistency with their OD (55.9%), which was associated with the wish to improve PT with daily life odors (64.4%; r=-0.386; P=0.001). In 53.4% of cases, patients realized that they were able to smell some odors thanks to PT. Patients with parosmia reported less positive opinion of PT compared to those with anosmia/hyposmia. CONCLUSION: Two thirds of patients with OD have good opinion of PT. Patients with anosmia or hyposmia reported better opinion than those with parosmia, strengthening the importance to consider specific PT dedicated to parosmia for this population. The inclusion of patients' daily life odors in PT is a potential point of improvement for future studies.
Mazet M, Enzler F, Strelnikov K
… +1 more, Vannson N
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 May · PMID 41741243
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PURPOSE: To facilitate the implementation of France's 2018 '100% santé' reform, requiring speech-in-noise (SPIN) audiometry for all ages, and building upon existing adult test reviews, this study surveyed pediatric tests...PURPOSE: To facilitate the implementation of France's 2018 '100% santé' reform, requiring speech-in-noise (SPIN) audiometry for all ages, and building upon existing adult test reviews, this study surveyed pediatric tests for potential French adaptation. METHOD: A systematic literature review of PubMed, Acoustical Society of America, and ScienceDirect databases used keywords related to speech, audiometry, children, and noise. Articles were screened, and data extracted via a reading grid, detailing test criteria: age, materials, conditions, SNR, administration, scoring, duration, translations, references, and evidence level. Tests were then scored for clinical use. RESULTS: From 4605 articles, 27 tests were identified, with 6 available in French for a pediatric population (FRA-SIMAT, VRB, DTT, HINT-C, SSI-ICM, and TMB). For screening, VRB, FRA-SIMAT, DTT, TMB and SSI-ICM offer accessible options for children aged five and above. For hearing aid applications, VRB and HINT-C were deemed most comprehensive. CONCLUSION: Developing French pediatric speech-in-noise audiometry standards, considering age-related effects, is crucial. Out of the 6 pediatric SPIN tests (available in French) found in this review, the DTT (headphones) is optimal for screening, and HINT-C (free field) for hearing aid use. In France, the VRB could be a promising solution for both screening and for auditory rehabilitation.
Thariat J, Dupin C, de Gabory L
… +1 more, REFCOR network
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Mar · PMID 41735111
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INTRODUCTION: The present REFCOR guidelines define indications for radiotherapy in sinonasal carcinoma and mucosal melanoma. METHODS: They result from multidisciplinary consensus based on a critical review of the literat...INTRODUCTION: The present REFCOR guidelines define indications for radiotherapy in sinonasal carcinoma and mucosal melanoma. METHODS: They result from multidisciplinary consensus based on a critical review of the literature, feedback from expert centers, and a structured process to harmonize clinical practice across France. RESULTS: Indications for radiotherapy are determined by tumor-specific characteristics and histoprognostic factors. In France, treatment decisions for these tumors are discussed in regional or national REFCOR expert panel multidisciplinary tumor boards. Radiotherapy is most often adjuvant, delivered at a short postsurgical interval, but can be exclusive for unresectable tumors or when surgery is contraindicated. It should be performed by experienced teams. The timing of postoperative treatment and the tumoral and nodal targets are tailored to histology and disease stage; their definition is based on a comprehensive and accurate characterization of surgical specimens, including multibloc resections obtained through open or endoscopic endonasal approaches. Given the anatomical proximity of the paranasal sinuses to highly radiosensitive structures (neurological, optic, otologic, and mucosal), technique and quality are critical for achieving tumor control while minimizing morbidity. Conformal techniques such as IMRT or VMAT represent the current gold standard. Proton therapy may be considered to improve sparing of organs at risk. CONCLUSION: The REFCOR guidelines establish a framework for indications for precision radiotherapy within a multidisciplinary patient-centered approach adapted to individual tumor characteristics. For each patient, recommendations are complemented by REFCOR multidisciplinary tumor board discussion in a personalized care pathway.
Asimakopoulos AD, Arquero Dominguez C, Avagnina A
… +1 more, Bouayed S
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 May · PMID 41723098
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INTRODUCTION: Hypopharyngeal perforation is a rare but potentially life-threatening complication that can follow cervical or aerodigestive procedures. Its deep anatomical location and often subtle symptoms make early rec...INTRODUCTION: Hypopharyngeal perforation is a rare but potentially life-threatening complication that can follow cervical or aerodigestive procedures. Its deep anatomical location and often subtle symptoms make early recognition difficult, increasing the risk of mediastinitis and sepsis. Massive hematemesis as the initial manifestation is exceptionally uncommon and diagnostically challenging. CASE SUMMARY: A 49-year-old man underwent elective C4-C5 anterior cervical discectomy for degenerative canal stenosis. Shortly after extubation, he developed massive hematemesis. Endoscopy revealed a perforation of the right pyriform sinus, with a Redon suction drain traversing the hypopharyngeal wall into the laryngeal lumen. Emergency direct pharyngolaryngoscopy was performed; the drain was carefully removed and the defect closed endoscopically with interrupted sutures reinforced by biological fibrin sealant. The postoperative course was uneventful, and at three-month follow-up the patient showed complete recovery without stenosis or fistula. DISCUSSION: This case describes an exceptionally rare iatrogenic hypopharyngeal perforation caused by a Redon suction drain after anterior cervical discectomy, presenting atypically with massive hematemesis. It highlights the diagnostic challenge and potentially dramatic presentation of hypopharyngeal perforation following anterior cervical spine surgery. The report underscores the importance of meticulous drain placement, intraoperative vigilance, and postoperative airway and swallowing surveillance in preventing aerodigestive complications after cervical or transoral procedures.
Hassan CH, Baglin AC, Baujat B
… +15 more, Coste-Martineau V, de Bonnecaze G, Digue L, Dupin C, Even C, Ferrand FR, Rumeau C, Michel J, Moya-Plana A, Radulesco T, Thariat J, Vergez S, Vérillaud B, Monnot C, de Gabory L
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Mar · PMID 41720745
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INTRODUCTION: The first guidelines of the French Expertise Network on Rare ENT Cancers (REFCOR) on the management of nasal cavity and sinus cancer date back to 2009. The objective of the present study was to update these...INTRODUCTION: The first guidelines of the French Expertise Network on Rare ENT Cancers (REFCOR) on the management of nasal cavity and sinus cancer date back to 2009. The objective of the present study was to update these guidelines using a search of the literature between 2009 and 2020. METHOD: The literature analysis was carried out using PRISMA criteria to enrich the previous literature review; 250 studies were selected out of 1696 analyzed. General considerations were formulated, common to all histologies and specific to each. The formalized expert consensus method was used to revise the old guidelines and propose new ones. RESULTS: The scientific analysis led to 87 recommendations: common to all sinonasal cancers (1 to 10), and for adenocarcinoma (11 to 28), adenoid cystic carcinoma (29 to 42), squamous cell carcinoma (43 to 53), mucosal melanoma (54 to 66), neuroblastoma (67 to 72) and undifferentiated carcinoma (73 to 87). According to first 10 guidelines, management of sinonasal cancer requires multidisciplinary teamwork, specifically trained teams and multidisciplinary tumor board meetings, and the emergence of new anatomopathological entities requires in-depth histological and immunophenotypic investigation. CONCLUSION: The present article provides a short version of the updated review validating the first 10 guidelines for diagnostic and therapeutic action on general themes common to all histologies.
Lépine C, Castain C, Baglin AC
… +1 more, Costes-Martineau V
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Mar · PMID 41702743
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The nasal cavities and sinuses are the site of many tumoral entities, which are increasingly well described, especially since the advent of molecular biology. The present systematic review collates the current state of k...The nasal cavities and sinuses are the site of many tumoral entities, which are increasingly well described, especially since the advent of molecular biology. The present systematic review collates the current state of knowledge on six new entities described in the 2017 and 2022 versions of the WHO classification of sinonasal tumors: DEK::AFF2 rearranged squamous cell carcinoma, HPV-associated multiphenotypic sinonasal carcinoma, NUT carcinoma, SMARCB1-deficient and SMARCA4-deficient carcinoma, biphenotypic sinonasal sarcoma, and adamantinoma-like Ewing sarcoma. A systematic literature search was performed on PubMed. The inclusion criteria focused on English-language articles precisely describing the histologic, immunohistochemical, molecular, clinical and prognostic characteristics of these entities. It is essential to be able to identify these entities, as they have distinct profiles in terms of progression and prognosis compared to other sinonasal tumors. The present study exhaustively describes their clinical and pathologic characteristics.
Chebib E, Orofino G, Couloigner V
… +1 more, Simon F
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Feb · PMID 41667366
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For pediatric myringoplasty, otoendoscopy is less invasive than traditional microscopic surgery, enabling a wide-angle view and precise identification of anatomic and pathological structures. It has significant advantage...For pediatric myringoplasty, otoendoscopy is less invasive than traditional microscopic surgery, enabling a wide-angle view and precise identification of anatomic and pathological structures. It has significant advantages, with high rates of tympanic closure, shorter operating time and simpler postoperative course. Bleeding, however, notably in children's narrow auditory canals, is a major problem, impairing visibility and complicating surgery. There are various techniques for dealing with it: cautious infiltration of the external auditory canal, and adrenaline-soaked cotton pledgets help reduce bleeding locally and absorb excess blood while keeping the tympanomeatal flap raised, increasing the workspace and protecting the flap against the instruments. Specific instruments such as suction elevators allow the surgeon to operate with a single hand while maintaining optimal visibility. Associated to controlled anesthesia with moderate hypotension and controlled hypocapnia, these techniques ensure effective management of bleeding, making the endoscopic approach more comfortable and reliable.
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Mar · PMID 41654414
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INTRODUCTION: Giant arachnoid granulation can induce lateral sinus stenosis with sigmoid sinus dehiscence, causing pulsatile tinnitus with pulsatile tympanic membrane without retrotympanic mass. CASE REPORT: A 78 year-ol...INTRODUCTION: Giant arachnoid granulation can induce lateral sinus stenosis with sigmoid sinus dehiscence, causing pulsatile tinnitus with pulsatile tympanic membrane without retrotympanic mass. CASE REPORT: A 78 year-old man presented unilateral left pulsatile tinnitus since 2009, with recent aggravation. Otoendoscopy showed a pulsatile tympanic membrane, in which movement was halted by jugular compression or Valsalva maneuver. CT angiography and MRI found large arachnoid granulation causing left lateral sinus stenosis and eroding the sigmoid sinus wall. Stenting resolved the tinnitus, while the eardrum remained pulsatile. DISCUSSION: Giant arachnoid granulation can induce lateral sinus stenosis and sigmoid sinus dehiscence, with turbulent venous flow and pulsatile tinnitus. The erosion can transmit cerebrospinal fluid pulsation to the sigmoid sinus and then to the tympanic membrane, where it is visible on otoscopy when the membrane is fragile.
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 May · PMID 41654413
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INTRODUCTION: Injection laryngoplasty with hyaluronic acid (HA) is currently the first-line treatment for glottic insufficiency, significantly improving vocal function. Some rare inflammatory laryngeal reactions have bee...INTRODUCTION: Injection laryngoplasty with hyaluronic acid (HA) is currently the first-line treatment for glottic insufficiency, significantly improving vocal function. Some rare inflammatory laryngeal reactions have been reported, managed conservatively by corticosteroids and antibiotics. CASE REPORT: An 83-year-old woman with longstanding dysphonia due to left laryngeal paralysis was treated by medialization with hyaluronic acid injection under local anesthesia. Postoperative course featured onset of dyspnea 42h after injection, with a large laryngeal edema, unimproved by conservative medical treatment. CT showed edematous infiltration of the left hemilarynx, greater than the injected volume. Given the lack of clinical improvement, emergency tracheotomy was performed. Progressive absorption of the edema allowed decannulation 3weeks later. DISCUSSION: We report a rare complication after medialization by HA injection: a severe inflammatory laryngeal reaction significantly impairing airway function and threatening vital prognosis. The case highlights the critical need for close monitoring after medialization and for appropriate management in case of dyspnea onset.
Saroul N, Petersen JE, Lambert C
… +7 more, Puechmaille M, Gilain L, Mom T, Dauvilliers Y, Fantini ML, Beudin P, Akkari M
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 May · PMID 41654409
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OBJECTIVES: Because access to sleep recordings is limited, there is a need for new reliable tools for pediatric obstructive sleep apnea-hypopnea syndrome (OSAHS) diagnosis. A score calculated from a 30 minutes-home sleep...OBJECTIVES: Because access to sleep recordings is limited, there is a need for new reliable tools for pediatric obstructive sleep apnea-hypopnea syndrome (OSAHS) diagnosis. A score calculated from a 30 minutes-home sleep video recording (VR) has already been proposed in 1996 with interesting results. The main objective of this pilot study was to assess the reliability of a similar score applied to reference PSG VR and calculated on two different time windows (30 and 10minutes). METHODS: A retrospective monocenter study was made on 16 children suspected of OSAHS, that underwent VR during overnight PSG. Video analysis was made during the second complete sleep cycle. A 30-minute risk score (RS30) and a 10-minute risk score (RS10) were established by analyzing seven parameters. The RS30 and RS10 were correlated with clinical examination data, a sleep questionnaire, the obstructive-apnea-hypopnea index (OAHI) and the oxygen desaturation index (ODI) from synchronized PSG results. RESULTS: There was a significant correlation between both the RS30 and RS10, the OAHI and ODI. A RS30 ≥6.09 was predictive of an OAHI ≥5 per hour with a sensitivity of 83% and a specificity of 90%. A RS10 ≥6.50 was predictive of an OAHI ≥5 per hour with a sensitivity of 67% and a specificity of 100%. CONCLUSION: A risk score based on PSG VR shows a good correlation with PSG results, confirming previous reports. Further work should focus on applying this risk score to home sleep VR for the diagnosis of pediatric OSAHS.