Dubernard X, Ortega Solis J, Fraysse MJ
… +3 more, Tronche S, Darrouzet V, Mom T
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Jan · PMID 41478836
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INTRODUCTION: Menière's disease is a fluctuating pressure pathology featuring successive hydropic episodes of varying frequency and intensity. The accumulation of these episodes and of the certain treatments can induce v...INTRODUCTION: Menière's disease is a fluctuating pressure pathology featuring successive hydropic episodes of varying frequency and intensity. The accumulation of these episodes and of the certain treatments can induce vestibular deficit and episodes of chronic instability. Vestibular rehabilitation aims to limit everyday impact by developing compensation and adaptation. How and when should it be introduced? MATERIAL AND METHODS: A systematic review of the literature for the period 1963-2022 was conducted by an expert group comprising of ENT physicians and vestibular physiotherapists. For each reference, the level of evidence was recorded as 1, 2, 3, 4 or expert opinion. Recommendations were graded A, B or C according to the methodological quality of the underlying studies; when there was no evidence-based consensus, an "expert opinion" was formulated based on the group members' clinical practices. RESULTS: Eighteen articles were selected via 4 scientific search engines (PubMed, Google Scholar, PEDro, Science Direct) and 3 keywords "Rehabilitation", "Vestibular rehabilitation", and "Menière's disease". CONCLUSION: Vestibular rehabilitation is recommended in Menière's disease in case of uncompensated spontaneous progressive vestibular deficit or surgical or medical vestibular suppression (gentamicin injection). Rehabilitation should await a period of 3 months' stability, and be adapted to the individual complaint. It should be supervised by a rehabilitation professional: self-rehabilitation is not recommended.
Bocquillon T, Mosnier I, Marx M
… +5 more, Petit G, Truy E, Lina-Granade G, Reynard P, Hermann R
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 May · PMID 41419372
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INTRODUCTION: Cochlear implantation (CI) is an option for severe to profound hearing loss when hearing aids are ineffective. This study aimed to evaluate its relevance in individuals over 80 by assessing long-term CI use...INTRODUCTION: Cochlear implantation (CI) is an option for severe to profound hearing loss when hearing aids are ineffective. This study aimed to evaluate its relevance in individuals over 80 by assessing long-term CI use and audiological outcomes. METHODS: We conducted a retrospective, single-center study including 29 patients over 80years old who received their first CI between January 2012 and December 2021 with data recorded until December 2024. Annual rates of users and non-users, audiometric test results, and pre- and postoperative complications were recorded. RESULTS: The mean age at implantation was 82.8, and the mean duration of CI usage was 4.9years. The percentage of patients still using their implant was 100%, 93%, 83%%, 76% and 75% at 1, 2, 3, 4 and 5years respectively. This number dropped to 33% 8years after the surgery. The main reasons for discontinuation were loss of autonomy and lack of benefit. Audiometric results showed improvement in mean pure-tone audiometry thresholds and free-field speech audiometry. Minor complications occurred in 24% of cases, while severe complications occurred in 13%. CONCLUSION: CI is a viable option for patients over 80years old with severe to profound hearing loss. However, given the progressive decline of usage after implantation in this age group, a detailed cost-benefit analysis could provide valuable insight into its indication for this population.
Frija J, Béquignon E, Laccourreye L
… +3 more, Atallah I, Gagnadoux F, Tamisier R
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Jan · PMID 41419371
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OBJECTIVES: To update practices for setting up, follow-up and indications in hypoglossal nerve stimulation in France. METHODS: Analysis of Medline, Cochrane and Embase databases (1970-2024), with assessment of techniques...OBJECTIVES: To update practices for setting up, follow-up and indications in hypoglossal nerve stimulation in France. METHODS: Analysis of Medline, Cochrane and Embase databases (1970-2024), with assessment of techniques, follow-up modalities, results and side effects. Six physicians (3 ENT specialists, 3 pulmonologists, all involved in hypoglossal stimulation) took part in a work-group between January 2024 and January 2025. RESULTS: Only one implant, Inspire IV, is available in France, indicated for non-obese (BMI<32kg/m) patients with moderate-to-severe obstructive sleep apnea-hypopnea syndrome (OSAHS) (apnea/hypopnea index [AHI] 15-50/h), and failure of or contraindications for continuous positive airway pressure (CPAP) or mandibular advancement device (MAD). Prior drug-induced sleep endoscopy (DISE) is mandatory. Studies show a 68% decrease in AHI, 70% decrease in oxygen desaturation index (ODI) at 12months, and improvements in somnolence and quality of life, which seem stable at 36months. About 25% of patients experience side effects, which are mostly transient. Final set-up requires polysomnography; follow-up requires clinical examination and/or poly(somno)graphy. CONCLUSION: This new alternative treatment in France should be proposed for symptomatic patients with failure of CPAP or MAD, rigorously screened in multidisciplinary centers.
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 May · PMID 41387130
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OBJECTIVES: This study aimed to measure and compare nasal mucus cystatin SN levels in patients with controlled and uncontrolled chronic rhinosinusitis, and to evaluate its diagnostic performance in distinguishing between...OBJECTIVES: This study aimed to measure and compare nasal mucus cystatin SN levels in patients with controlled and uncontrolled chronic rhinosinusitis, and to evaluate its diagnostic performance in distinguishing between these disease states. MATERIAL AND METHODS: A total of 98 CRS patients were prospectively enrolled and evaluated for disease control based on the EPOS criteria. Specimens of nasal mucus and tissue from patients with CRS and 15 healthy controls undergoing surgery for the deviated septum were obtained to measure cystatin SN levels. Disease severity was evaluated using the 22-item Sinonasal Outcome Test (SNOT-22), Questionnaire of Olfactory Disorders Negative Statements (QOD-NS) score, Lund-Kennedy score, Lund-Mackay score, olfactory cleft endoscopy scale (OCES), and olfactory cleft computed tomography (CT) score. Multivariable logistic regression analysis was used to determine the risk factors associated with uncontrolled CRS. RESULTS: Among the patients with CRS, 42.86% were uncontrolled. Cystatin SN expression in the nasal epithelium was significantly increased among patients with uncontrolled CRS compared to those with controlled CRS and healthy controls (both P<0.001). Furthermore, the uncontrolled CRS exhibited significantly higher blood eosinophil counts (BEC) (P=0.001), SNOT-22 score (P=0.001), QOD-NS score (P=0.004), Lund-Mackay score (P=0.022), OCES (P=0.004), and olfactory cleft CT score (P=0.012) than controlled CRS. Additionally, mucus cystatin SN levels showed a positive correlation with BEC (R=0.126, P=0.012) in patients with CRS. Multivariable logistic regression analysis showed that nasal mucus cystatin SN was identified as an independent predictor of uncontrolled CRS (OR=1.011, P=0.028). Mucus cystatin SN levels with a cutoff point greater than 106.050pg/mL had a superior predictive value for uncontrolled CRS compared to BEC (area under the curve, 0.886 vs. 0.782, P<0.001). CONCLUSION: Mucus cystatin SN levels were highly associated with disease severity in patients with uncontrolled CRS.
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Mar · PMID 41365762
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INTRODUCTION: Sclerotherapy is one of the treatment modalities for macrocystic lymphatic malformations. Nerve complications related to the toxicity of the sclerosing agent have already been described. We report the first...INTRODUCTION: Sclerotherapy is one of the treatment modalities for macrocystic lymphatic malformations. Nerve complications related to the toxicity of the sclerosing agent have already been described. We report the first known case of bilateral hypoglossal nerve palsy following ethanol sclerotherapy. CASE SUMMARY: An 11-year-old boy underwent ethanol sclerotherapy for a monocystic lymphatic malformation of the floor of the mouth. He presented with bilateral paralysis of the XII cranial nerves postoperatively, which fortunately resolved within approximately 5 months. DISCUSSION: The potential side effects associated with the diffusion of the sclerosing agent must be anticipated even beyond the predictable anatomical limits. Paralysis related to local ethanol toxicity is reversible in most cases.
André M, Culié D, Malard O
… +6 more, Marhic A, Fabre C, Martin J, Babin E, Vergez S, Morinière S
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 May · PMID 41354573
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AIM: To determine factors affecting pain on a numeric rating scale (NRS) during office-based voice prothesis exchange. And, secondarily, to review voice prothesis replacement techniques in France. MATERIAL AND METHOD: A...AIM: To determine factors affecting pain on a numeric rating scale (NRS) during office-based voice prothesis exchange. And, secondarily, to review voice prothesis replacement techniques in France. MATERIAL AND METHOD: A multicenter prospective observational study was conducted by the Head and Neck Tumor Study Group (GETTEC) between November 2022 and November 2024. A survey questionnaire was filled out by the practitioner after informed consent was obtained from the patient. All laryngectomized patients presenting in consultation for voice prothesis exchange were included. Pain was assessed on a unidimensional 0-10 numeric rating scale. RESULTS: Three hundred and nine questionnaires were collected. Mean pain rating was 2±2.8. Three factors were associated with significantly lower pain intensity: procedure duration <5minutes (P<0.001), a single attempt (P<0.001), and the status of the practitioner performing the replacement (P=0.002); 2 factors were associated with suggestively lower pain intensity: male gender (P=0.030), and use of a capsule (P=0.011). Pain intensity was not significantly associated with local anesthesia (P=0.4) or the extraction technique (P=0.2). Sixty seven percent of replacements were in emergency contexts, particularly for intra-prosthetic leakage (68%). Local anesthesia was used in 87% of cases. Extraction was by pushing the implant into the esophagus in 52% of cases, and by pulling it out in 48%. Most replacements (75%) required only 1 attempt, and 77% required less than 5minutes (77%). Capsules were used in 23% of cases. CONCLUSION: We found a wide range of techniques for replacing a voice prothesis. The procedure is quick and relatively painless. For replacement that is as painless as possible, it is advisable for it to be carried out quickly, using a capsule.
Chun WB, Chernov ES, Chen K
… +5 more, Nguyen SA, Marrero-Gonzalez AR, Stevens MN, Drawdy AV, Kejner AE
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Jan · PMID 41353055
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Sex differences in cancer survival are well-established but understudied in oropharyngeal squamous cell carcinoma (OPSCC). We evaluated the impact of sex on OPSCC survival with emphasis on geographic variation. A systema...Sex differences in cancer survival are well-established but understudied in oropharyngeal squamous cell carcinoma (OPSCC). We evaluated the impact of sex on OPSCC survival with emphasis on geographic variation. A systematic review through June 2025 identified 84 studies (N=451,136) from the United States (n=47) and non-United States cohorts (n=37). Meta-analyses assessed hazard ratios, proportions, and means. Most patients were male (80.8%; mean age 59.9years). HPV-positive OPSCC was more prevalent in the US (73.8%) than non-US countries (44.0%, P<0.0001). US males had improved overall (HR=1.13 [1.07-1.19]) and cause-specific survival (HR=1.11 [1.01-1.21]) than females. Non-US females had better OS (HR=0.86 [0.77-0.95]) and CSS (HR=0.63 [0.43-0.92]) than males. No significant differences were observed in other survival measures. Sex appears to influence OPSCC survival, with differing trends between US and non-US populations. These geographic differences likely reflect differences in HPV status. Further research stratified by sex and HPV status is needed to clarify these relationships and guide tailored interventions.
Dauzier E, Lazard D, Sain Oulhen C
… +2 more, Genty E, Lecanu JB
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 May · PMID 41193299
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OBJECTIVES: To compare early results in isolated ossiculoplasty under potentialized local anesthesia and general anesthesia. MATERIAL AND METHOD: A single-center retrospective observational study included 123 consecutive...OBJECTIVES: To compare early results in isolated ossiculoplasty under potentialized local anesthesia and general anesthesia. MATERIAL AND METHOD: A single-center retrospective observational study included 123 consecutive patients treated by isolated ossiculoplasty between September 1, 2019 and March 1, 2021 in a French private hospital. The main aim was to compare the management pathway (operating room time, hospital stay, outpatient management rate, "by-pass" rate of direct return to the outpatient department without passing through the recovery room) according to potentialized local anesthesia versus general anesthesia. Secondary endpoints comprised audiometric results and post- and intraoperative complications (nausea and vomiting, pain, dizziness, crossover). The significance threshold was set at P<0.005. The STROBE guideline was followed. RESULTS: In total, 123 patients were included: 41 with local and 82 with general anesthesia. The two groups were comparable except for type of surgeon. The rate of outpatient treatment was significantly greater with local anesthesia (93% vs. 55%). Operating time and operating room, recovery room and outpatient room occupancy times were shorter with local anesthesia. Postoperative dizziness was significantly more frequent with general anesthesia. Audiometric results did not differ. CONCLUSION: Potentialized local anesthesia can improve organizational management and outpatient rates in ossicular surgery, without impairing the quality of results.
Cervini MM, Nguyen DH, Haroun F
… +2 more, Deneuve S, Mirghani H
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 May · PMID 41173770
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Postoperative monitoring of free flaps has traditionally been based on clinical assessment, interpretation of which may be subjective. The Cook-Swartz implantable Doppler probe enables continuous objective real-time moni...Postoperative monitoring of free flaps has traditionally been based on clinical assessment, interpretation of which may be subjective. The Cook-Swartz implantable Doppler probe enables continuous objective real-time monitoring of blood flow at microvascular anastomoses. We report our experience with a cohort of 181 consecutive patients operated on between 2019 and 2025. Arterial placement of the probe was preferred after an initial experience of venous monitoring, and provided a clear and easily interpretable signal. The device demonstrated excellent diagnostic accuracy, with a positive predictive value of 100% for the detection of vascular anomalies. However, early detection does not always guarantee flap salvage. Clinical examination remains indispensable, particularly for detecting venous thromboses that may be overlooked on arterial monitoring alone. The Cook-Swartz implantable Doppler system is a reliable easy-to-use adjunct to clinical monitoring of free flaps in head and neck reconstruction.
Chandrakumar C, Bétolaud FX, Noël-Petroff N
… +3 more, Deray T, Van Den Abbeele T, Bois E
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Mar · PMID 41130892
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The present cross-sectional study compared efficacy between two quality-of-life questionnaires for cochlear implanted children: CIQOL-10 Global and PEACH. Forty cochlear implanted children, aged 18 months to 15 years, we...The present cross-sectional study compared efficacy between two quality-of-life questionnaires for cochlear implanted children: CIQOL-10 Global and PEACH. Forty cochlear implanted children, aged 18 months to 15 years, were included over a 3-month period. Children not wearing the implant, from non-French-speaking families, with psychomotor retardation or neurologic deficit were excluded. Ease of filling out the questionnaires and their relevance were assessed on Visual Analog Scales. The aim was to select the questionnaire better adapted to an implanted pediatric population. PEACH scored significantly better than CIQOL for ease of use and relevance, particularly for under-6 year-olds. On average, 3 of the 10 CIQOL questions went unanswered for children aged≤6 years, versus just 1 out of 13 for PEACH. PEACH, being easier to answer and more relevant, particularly for younger children, can optimize follow-up of cochlear implanted children.
Toulemonde P, Lemesre PE, Bertholon P
… +2 more, Vincent C, Schmerber S
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Mar · PMID 41130890
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Benign paroxysmal positional vertigo is one of the commonest forms of vertigo. The lateral semicircular canal is involved in 5-30% of cases, although this is probably an underestimation. Diagnostic and therapeutic proced...Benign paroxysmal positional vertigo is one of the commonest forms of vertigo. The lateral semicircular canal is involved in 5-30% of cases, although this is probably an underestimation. Diagnostic and therapeutic procedures depend on otolithic debris location in the canal, and require a certain expertise. The difficulty in diagnosis lies in locating the debris and determining the affected side, which are prerequisites for effective therapeutic maneuvers. The present study describes the main diagnostic and therapeutic techniques for lateral semicircular canal lithiasis.
de Bressieux E, Rouillon I, Simon F
… +3 more, Parodi M, Bondi T, Loundon N
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Mar · PMID 41109787
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AIM: The ABR (auditory brainstem response) and ASSR (auditory steady-state response) electrophysiological tests are fundamental for accurate early diagnosis of hearing loss in young children, and are included in objectiv...AIM: The ABR (auditory brainstem response) and ASSR (auditory steady-state response) electrophysiological tests are fundamental for accurate early diagnosis of hearing loss in young children, and are included in objective hearing assessment, particularly in neonatal post-screening. The main aim of the present study was to compare hearing thresholds obtained by ASSR, ABR and behavioral audiometry at different frequencies. The secondary aims were to compare these in the severe to profound hearing loss group, and to determine the sensitivity and specificity of ASSR and ABR in the diagnosis of hearing loss in young children so as to improve diagnostic strategy. MATERIAL AND METHODS: A retrospective observational study was carried out between January 2017 and June 2020, following STROBE guidelines. Data from 112 children (218 ears) aged 2 months to 4 years tested by ASSR, ABR and behavioral audiometry were analyzed. RESULTS: Hearing thresholds were comparable between ABR and ASSR, including in the severe to profound deafness group. Sensitivity and specificity of ASSR were 0.922 and 0.892 respectively, and for ABR 0.907 and 0.730. CONCLUSION: In most cases, hearing thresholds were comparable between ASSR and ABR, and especially in the severe to profound deafness group. ASSRs are now part of the systematic diagnostic work-up, providing information complementary to ABR. The accuracy of the ASSR test has been improved by incorporating corrective factors from pediatric databases. Considering children's limited sleep time, the excellent correlation between ABR and ASSR at 2000-4000Hz suggests that assessment should begin with ABR and continue with ASSR at 1000 then 500Hz in order to broaden the frequency range studied. Diagnosis of moderate hearing loss remains a challenge, with high rates of improvement and loss to follow-up; incorporating bone-conduction ASSR or ABR could facilitate management by rapidly ruling out any additional conduction factor.
Carsuzaa F, Ayraud-Thevenot S, Dufour X
… +2 more, Guihenneuc J, Favier V
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Mar · PMID 41087248
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INTRODUCTION: Drug-induced sleep endoscopy (DISE) is widely used for assessment of obstructive sleep apnea, using either disposable or reusable fiberendoscopes. The present study compared the environmental, economic and...INTRODUCTION: Drug-induced sleep endoscopy (DISE) is widely used for assessment of obstructive sleep apnea, using either disposable or reusable fiberendoscopes. The present study compared the environmental, economic and social impact of DISE between disposable and reusable fiberendoscopy. METHODS: Ten DISE procedures were analyzed. The carbon footprint, expressed in kgCOeq, included patient and staff transport, operating room energy consumption, waste management, medical device production, delivery, and sterilization. Financial costs and healthcare professionals' perceptions were also evaluated via structured questionnaires. RESULTS: The baseline carbon footprint of a DISE procedure (excluding the endoscope) was 23.95kgCOeq. Using a disposable fiberendoscope increased the total footprint to 65.05kgCOeq, while a reusable endoscope resulted in an extra 14.18kgCOeq. Financially, a single procedure cost €206 with the disposable device versus €17.60 with the reusable one. Professionals associated reusable fiberendoscopes with better quality, ecological benefit and lower cost, but noted concerns about infection control and the complexity of sterilization. Disposable devices were preferred for their ease of use but criticized for their environmental and economic impact. CONCLUSION: Reusable fiberendoscopes offer clear environmental and economic advantages over disposable ones, without compromising clinical outcome. Promoting their use can help reduce the ecological footprint of healthcare systems while maintaining high-quality care.
Eur Ann Otorhinolaryngol Head Neck Dis
· 2026 Mar · PMID 41087247
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Post-COVID-19 olfactory dysfunction (PCOD) typically resolves within weeks to months; however, persistent cases exist in approximately 10% of patients beyond a year. This study investigated the role of olfactory cleft ad...Post-COVID-19 olfactory dysfunction (PCOD) typically resolves within weeks to months; however, persistent cases exist in approximately 10% of patients beyond a year. This study investigated the role of olfactory cleft adhesions in prolonged PCOD and evaluated surgical intervention as a treatment option. Four cases of PCOD unresponsive to medical therapy underwent endoscopic sinus surgery (ESS) to address bilateral olfactory cleft obstruction identified on computed tomography (CT) scan. Adhesions between the superior/middle turbinates and nasal septum were surgically divided, and silicone plates were inserted to prevent reattachment. All patients reported significant subjective improvements in olfaction within one week of silicone removal. Objective olfactory test scores continued to improve over subsequent months, and postoperative CT scan confirmed improved ventilation of the olfactory cleft. These findings suggest that adhesions formed during inflammatory healing contribute to conductive olfactory dysfunction in Long-COVID cases, distinct from sensorineural or central OD. Surgical intervention may be beneficial for carefully selected patients with PCOD persisting for at least one year, anosmia or severe olfactory loss confirmed by testing, and CT evidence of olfactory cleft obstruction. However, the risks such as mucosal damage and potential worsening or no improvement of OD should be discussed thoroughly. Individualized treatment strategies are recommended, and further studies are warranted to optimize management of persistent PCOD.