Shanghai Kou Qiang Yi Xue = Shanghai Journal Of Stomatology[JOURNAL]
Sun
200 papers
[The impact of oral occlusal exercises on occlusal performance of oral cancer patients following segmental mandibulectomy without simultaneous reconstruction].
Yang L, Zhou T, Zhao N … +4 more , Qu X, Chen W, Zhao Y, Hou L
Shanghai Kou Qiang Yi Xue · 2025 Apr · PMID 40550772
PURPOSE: To investigate the effects of oral occlusion exercises on occlusal performance of oral cancer patients who underwent segmental mandibular resection without simultaneous reconstruction. METHODS: From October 2022...
PURPOSE: To investigate the effects of oral occlusion exercises on occlusal performance of oral cancer patients who underwent segmental mandibular resection without simultaneous reconstruction. METHODS: From October 2022 to May 2023, a total of 63 oral cancer patients who underwent segmental mandibular resection without reconstruction at the Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine were selected. They were randomly divided into control group (30 patients) and experimental group (33 patients). The control group received conventional care, while the experimental group underwent oral occlusion exercises except conventional care. After three months, the maximum total occlusal force(TOF), asymmetry index of occlusal force(AOF), center of occlusal force(COF), and mastication efficiency of both groups were compared. Statistical analysis was conducted using SPSS 26.0 software package. RESULTS: Compared with the control group, TOF in the experimental group was increased, AOF and COF were decreased, and the differences were statistically significant(P＜0.01). The masticatory efficiency of the experimental group was significantly better than that of the control group(P＜0.01). CONCLUSIONS: Oral occlusal exercises can improve occlusal performance in patients with mandibular resection without reconstruction, but larger sample size and rigorous design are needed to further verify its clinical effect and mechanism.
[Measurement of deciduous canine and construction of standardized virtual crown based on ray projection].
Sang X, Ding Z, Yan F … +5 more , Yao N, Kong J, Zhai L, Mei Y, Ji D
Shanghai Kou Qiang Yi Xue · 2025 Apr · PMID 40550771
PURPOSE: To explore the construction process of a standard virtual crown for deciduous canine teeth, provide a foundation for the establishment of a standard crown model for deciduous canine teeth, and reference and basi...
PURPOSE: To explore the construction process of a standard virtual crown for deciduous canine teeth, provide a foundation for the establishment of a standard crown model for deciduous canine teeth, and reference and basis for the application of CAM/CAM technology in pediatric dentistry. METHODS: A total of 65 children aged 4-5 years old with caries free deciduous canine were selected from the Imaging Department of Nantong Stomatological Hospital, including 34 boys and 31 girls. The obtained DICOM format data was imported into 3DSlicer 5.0.3 software for ray projection rendering and reconstruction. Using the ruler tool in the software, crown data of deciduous teeth were extracted, crown width, thickness and length were measured, and the data were divided into male and female, upper and lower deciduous teeth for Student's t test. The reconstructed model was modified according to the test results, and the mean and median models of crown width, thickness and length of male/female upper/lower deciduous teeth were established. A vernier caliper was used to measure the isolated milk fangs. The results of virtual measurement and specimen measurement were compared by Student's t test. MATLAB R 2016a software was used for statistical analysis. RESULTS: There were significant differences in the three radial directions between males and females; There was a statistical difference in crown width and thickness between the upper and lower deciduous canines, but there was no significant difference in crown length. The average values of crown width, crown thickness, and crown length of girls' maxillary deciduous canines were 6.20, 3.97, and 5.61 mm, respectively, with a median of 6.15, 3.82 and 5.53 mm. The average values of crown width, crown thickness, and crown length of girls' mandibular deciduous canines were 5.47, 4.25 and 5.66 mm, respectively, with median values of 5.45, 4.22 and 5.68 mm, respectively. The average values of crown width, crown thickness, and crown length of male primary teeth were 6.40, 4.14 and 5.87 mm, respectively, with median values of 6.40, 4.04 and 6.05 mm. The average values of crown width, crown thickness, and crown length of male mandibular deciduous canines were 5.69, 4.53 and 6.00 mm, respectively, with median values of 5.64, 4.65 and 6.06 mm. Based on the above values, virtual crown mean and median models were established for male/female maxillary and mandibular deciduous canines. CONCLUSIONS: The diameter values obtained by ray projection and measurement in 3DSlicer have higher reliability compared to specimen measurements. The measurement results can be used to establish a virtual model of the male/female upper and lower primary canine standard crown, providing a reference for the establishment of the primary canine standard crown model.
[The study on the effects of different shapes of nasopalatine canals on tooth movement and implantation during orthodontic and implant treatment with CBCT].
Zhu W, Shi X, Yang J … +1 more , Nie J
Shanghai Kou Qiang Yi Xue · 2025 Apr · PMID 40550770
PURPOSE: The aim of this study was to evaluate the impact of the nasopalatine canal(NPC) shape and its morphometric characteristics on expected teeth movement by assessing the distance to maxillary central incisors (MCIs...
PURPOSE: The aim of this study was to evaluate the impact of the nasopalatine canal(NPC) shape and its morphometric characteristics on expected teeth movement by assessing the distance to maxillary central incisors (MCIs) according to NPC type. METHODS: A total of 200 patients with CBCT imaging data meeting the inclusion criteria were selected. The nasopharyngeal canal in the sagittal plane was classified. The following parameters were obtained: incisor foramen diameter, nasopalatine canal length, anterio-posterior diameter of incisor foramen (A-P IF), anterio-posterior diameter of Stenson foramen (A-P NF), nasopalatine tube 1/2 length diameter(M-L IF), and the distance between NPC and MCIs. The data were analyzed with SPSS 26.0 software package. RESULTS: Diameter of incisor hole（P=0.045）, A-P IF（P=0.001）, M-L IF（P＜0.001）, A-P NF（P＜0.001） had significant difference. In cylindrical-shaped NPC, a significant correlation was observed for NPC length, while in funnel-shaped NPC, a significant correlation was observed for A-P IF and NPC length. In hourglass-shaped NPC, a significant correlation was observed for A-P IF, A-P NF, and NPC length. CONCLUSIONS: Each NPC shape showed specific impacts on the relationship between NPC diameters at different sections and distances to MCIs.
[Comparison of the effect of glass fiber and cobalt alloy post-core all-ceramic crowns on the restoration of anterior teeth].
Dong K, Lyu S, Zhang M
Shanghai Kou Qiang Yi Xue · 2025 Apr · PMID 40550769
PURPOSE: To compare the effect of glass fiber post core porcelain crown and cobalt alloy post core porcelain crown in repairing residual root and crown of the anterior teeth. METHODS: The data of 121 patients with residu...
PURPOSE: To compare the effect of glass fiber post core porcelain crown and cobalt alloy post core porcelain crown in repairing residual root and crown of the anterior teeth. METHODS: The data of 121 patients with residual root and crown of anterior teeth admitted to the hospital from January 2020 to December 2023 were reviewed, of which 61 patients were treated with glass fiber post-core porcelain crown restoration (experimental group) and 60 patients with cogger alloy post core all porcelain crown repair (control group). The repair outcomes of the two groups were recorded after 12 months of follow-up. The final results, aesthetic effect, periodontal health index, gingival crevicular fluid inflammatory factors and complications were compared between the two groups. SPSS 18.0 software package was used for statistical analysis of the data. RESULTS: The success rate of the experimental group was significantly higher than that of the control group (P＜0.05). There was no significant difference in pink esthetic scores (PES) and white aesthetic scores (WES) between the two groups before and after treatment (P＜0.05). The sulcus bleeding index (SBI), gingival index (GI) and plaque index (PLI) after treatment were significantly lower in both groups than before treatment (P＜0.05), and the experimental group after treatment was more lower(P＜0.05). TNF-α, IL-6 and IL-8 levels after treatment were significantly lower in both groups than before treatment (P＜0.05), and TNF-α and IL-6 levels in the experimental group after treatment were more lower (P＜0.05). There was no significant difference in the total complication rate between the two groups (P＞0.05). CONCLUSIONS: Compared to cobalt alloy post-core all-porcelain crown, glass fiber post-core all-porcelain crown can enhance the repair effect, improve periodontal health, inhibit the damage of gingival crevicular fluid inflammation.
[Evaluation of the efficacy of iRoot BP Plus combined with Nd:YAG laser in the treatment of cariogenic pulp exposure].
Zhou Y, Zhang X, Yuan J
Shanghai Kou Qiang Yi Xue · 2025 Apr · PMID 40550768
PURPOSE: To evaluate the pulp capping effect of iRoot BP Plus combined with Nd: YAG laser irradiation in the treatment of caries induced exposed pulp and its impact on pulp vitality and occlusal function recovery. METHOD...
PURPOSE: To evaluate the pulp capping effect of iRoot BP Plus combined with Nd: YAG laser irradiation in the treatment of caries induced exposed pulp and its impact on pulp vitality and occlusal function recovery. METHODS: From January 2022 to January 2023, a total of 196 patients with dental caries and exposed pulp, including 268 permanent teeth, were selected and randomly divided into the experimental group of 98 patients (136 teeth) and control group of 98 patients (132 teeth) using computer randomization. Both groups were treated with Nd:YAG laser after cleaning the caries. The experimental group was filled with iRoot BP Plus and the control group was filled with mineral trioxide polymer (MTA). The treatment efficacy, pulp vitality and occlusal function were compared between the two groups. SPSS 24.0 software package was used for statistical analysis of the data. RESULTS: There was no significant difference in the success rate of treatment between the two groups at 3, 6 and 12 months after surgery(P＞0.05). At 12 months after treatment, the bite force and chewing efficiency of the experimental group were significantly higher than those of the control group(P＜0.05). At 3, 6 and 12 months after treatment, the pulp vitality and pulp blood flow in both groups significantly decreased compared to preoperative levels (P＜0.05); the pulp vitality and pulp blood flow of the experimental group were significantly higher than those of the control group(P＜0.05). CONCLUSIONS: iRoot BP Plus combined with Nd: YAG laser in the treatment of cariogenic exposed pulp is helpful to preserve pulp vitality and improve occlusal function.
[Application of sliding vermilion flap in angulus oris defect after buccal mucosa cancer ablation].
Wu K, Wu H
Shanghai Kou Qiang Yi Xue · 2025 Apr · PMID 40550767
PURPOSE: To evaluate the effect of sliding vermilion flap in angulus oris defect after buccal mucosal cancer ablation. METHODS: A total of 33 patients with buccal mucosal cancer who underwent buccal mucosal cancer radica...
PURPOSE: To evaluate the effect of sliding vermilion flap in angulus oris defect after buccal mucosal cancer ablation. METHODS: A total of 33 patients with buccal mucosal cancer who underwent buccal mucosal cancer radical surgery and resection of angulus oris, and reconstructed with free anterolateral thigh flap transfer and sliding vermilion flap were collected from January 2015 to April 2021 in Department of Oral and Maxillofacial Surgery at Second Xiangya Hospital. Thirty-three patients with buccal mucosal cancer admitted to Department of Oral and Maxillofacial Surgery, Second Xiangya Hospital of Central South University from January 2015 to April 2021 were selected. All patients underwent combined buccal-mandibulectomy and neck radical operation and resection of oral angle, and underwent anterolateral femoral free flap and lip red elastic flap reconstruction. The angulus oris outcome, aesthetics outcome, masticatory efficacy, swallowing and speech function were assessed by FACT-HN (The Functional Assessment of Cancer Therapy-Head and Neck). The mouth opening was measured and recorded. SPSS 19.0 software package was used for statistical analysis of the data. RESULTS: The success rate of free flap transplantation was 100% in 33 patients. Although the aesthetics outcome was decreased at postoperative 1 year compared with that of preoperative duration (P＜0.001), there was no significant difference of angulus oris outcome at postoperative 1 year compared with that of preoperative duration (P＞0.05). Moreover, the masticatory function was significantly improved at postoperative 1 year compared with that of preoperative duration(P=0.004). However, there was no significant difference of speech and swallowing function at postoperative 1 year compared with that of preoperative duration (P＞0.05). The mouth opening was significantly improved at postoperative 1 year compared with that of preoperative duration(P＜0.05), and the satisfaction of mouth opening in these patients was 75.7%. CONCLUSIONS: The use of sliding vermilion flap can ideally repair the angulus oris, and offer a novel method to reconstruct defect of angulus oris.
[Evaluation of the efficacy of modified Twin-block appliance combined with micro-implant anchorage in the treatment of Angle Class Ⅱ division 1 malocclusion].
Lu C, Cui X, Cao P
Shanghai Kou Qiang Yi Xue · 2025 Apr · PMID 40550766
PURPOSE: To explore the effectiveness of improved Twin block appliances combined with micro-implant anchorage in correction of Class Ⅱ division 1 malocclusion. METHODS: A retrospective analysis of medical records of 96 p...
PURPOSE: To explore the effectiveness of improved Twin block appliances combined with micro-implant anchorage in correction of Class Ⅱ division 1 malocclusion. METHODS: A retrospective analysis of medical records of 96 patients with Class Ⅱ division 1 malocclusion treated at Rugao Hospital of Traditional Chinese Medicine from January 2018 to January 2022 was conducted. The patients were divided into experimental group (n=52) and control group (n=44) based on the treatment methods. The control group was treated with modified Twin-block appliance, while the experimental group was treated with modified Twin-block appliance combined with micro-implant anchorage. Comparison was made between the two groups regarding treatment duration, time to achieve bite opening, alignment time, ANB angle, SNB angle, SNA angle, U1-NA angle, U1-NB angle, U1-SN angle, L1-MP angle, upper lip protrusion(ULP), lower lip protrusion (LLP), Z angle, plaque index (PLI), gingival index (GI) and sulcus bleeding index (SBI). Complications and patient satisfaction were recorded. SPSS 24.0 software package was used for statistical analysis of the data. RESULTS: The treatment duration, time to achieve bite opening and alignment time in the experimental group were significantly shorter than those in the control group (P＜0.05). After treatment, ANB, U1-NA and U1-SN of the two groups were lower than before treatment, and the experimental group was significantly lower than the control group (P＜0.05). U1-NB and L1-MP were higher than those before treatment, and the experimental group was significantly higher than the control group (P＜0.05). There was no significant difference between SNB and SNA (P＞0.05). After treatment, ULP and LLP of the two groups were lower than before treatment, and the experimental group was significantly lower than the control group(P＜0.05). Z-angle of the experimental group was significantly higher than that of the control group(P＜0.05). PLI in the experimental group was significantly lower than that in the control group (P＜0.05). There was no significant difference between GI and SBI (P＞0.05), and there was no significant difference in satisfaction between the two groups(P＞0.05). CONCLUSIONS: The modified Twin-block appliance combined with micro-implant anchorage can help to shorten the treatment time, improve the jaw and facial soft tissue contour, and promote the recovery of dental aesthetics.
[A clinical control study of bleeding tendency and risk factors in patients with oral antithrombotic drugs after dental extractions].
Luo Q, Zhu Z, Shi H … +2 more , Zhou Q, Yu C
Shanghai Kou Qiang Yi Xue · 2025 Apr · PMID 40550765
PURPOSE: To explore the bleeding tendency and related risk factors of patients with or without oral antithrombotic drugs after tooth extraction, in order to provide theoretical reference for perioperative management of t...
PURPOSE: To explore the bleeding tendency and related risk factors of patients with or without oral antithrombotic drugs after tooth extraction, in order to provide theoretical reference for perioperative management of tooth extraction. METHODS: A cohort study was conducted among patients who attended the Cardiovascular Tooth Extraction Specialist Clinic of Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine from March 2023 to June 2023. The patients were divided into experimental group (medication group) and control group (no medication group) according to whether they took antithrombotic drugs for a long time. Teeth extraction was performed under ECG monitoring and postoperative bleeding was followed up to analyze the incidence of bleeding and related risk factors. SPSS 22.0 software package was used for data analysis. RESULTS: A total of 645 patients were included, including 305 patients in the medication group and 340 patients in the non-medication group. Bleeding events occurred in 17 cases (5.6%, 17/305) in the medication group and 1 (0.3%, 1/340) in the non-medication group, with significant difference between the two groups (P＜0.01). Binary logistic regression analysis showed that old age (OR: 4.089, 95%CI: 1.351-12.374, P=0.013) had a significant positive effect on postoperative bleeding. CONCLUSIONS: Oral antithrombotic drugs and advanced age are the risk factors for postoperative bleeding in patients with cardiovascular diseases undergoing tooth extractions.
[A study on the relationship between etiology and influencing factors of burning mouth syndrome].
Zhou H, Lin X
Shanghai Kou Qiang Yi Xue · 2025 Apr · PMID 40550764
PURPOSE: To analyze the etiology and related influencing factors of burning mouth syndrome (BMS). METHODS: A total of 109 patients with BMS who visited the Department of Stomatology of Shengjing Hospital of China Medical...
PURPOSE: To analyze the etiology and related influencing factors of burning mouth syndrome (BMS). METHODS: A total of 109 patients with BMS who visited the Department of Stomatology of Shengjing Hospital of China Medical University from November 2022 to October 2023 were selected, and 84 healthy volunteers who participated in the survey during the same period were selected as the control group. The basic information of the research subjects was recorded, and oral health status, periodontal health status and psychological status of the research subjects were evaluated. Student's t test, Chi-square test and binary logistic regression analysis were used to analyze the factors affecting the incidence of BMS with SPSS 27.0 software package. RESULTS: Mono-factor analysis showed that residual crown, residual root, periodontitis, anxiety status, depressive status, sleep disorders, menopause, diabetes, digestive system diseases and lacunar infarction were related to the incidence of BMS (P＜0.05). The variables with P＜0.1 in mono-factor analysis were selected for multivariate logistic regression analysis. The results showed that periodontitis, COVID-19, anxiety status, depressive status, sleep disorders, lacunar infarction, and digestive system diseases were factors affecting the incidence of BMS (P＜0.05 and OR＞1). CONCLUSIONS: The diagnosis and treatment of BMS require multidisciplinary cooperation of specialists such as psychiatry, neurology and gastroenterology, and active treatment of systemic or related diseases. In addition to strengthening oral hygiene and periodontal health management for patients, clinical practitioners should also pay attention to the aggravation of BMS patients' pain intensity, sleep quality and anxiety caused by COVID-19 pandemic, and provide timely psychological counseling to better control the development of BMS.
[Study on the correlation between the expression of Porphyromonas gingivalis, tumor-associated macrophages and the clinical prognosis of oral squamous cell carcinoma].
Li M, Li C, Wei W … +5 more , Chen C, Wang B, Gong Z, Guo W, Ren G
Shanghai Kou Qiang Yi Xue · 2025 Apr · PMID 40550763
PURPOSE: To explore the immunoexpression and clinical significance regarding Porphyromonas gingivalis (P.gingivalis) and tumor-associated macrophage (TAM) in the tumor microenvironment of oral squamous cell carcinoma (OS...
PURPOSE: To explore the immunoexpression and clinical significance regarding Porphyromonas gingivalis (P.gingivalis) and tumor-associated macrophage (TAM) in the tumor microenvironment of oral squamous cell carcinoma (OSCC). METHODS: A total of 200 OSCC patients admitted to the First Affiliated Hospital of Xinjiang Medical University between June 2008 and June 2020 were divided into P.gingivalis-strong-expression group(n=139) and P. gingivalis-weak-expression group (n=61), based on the immunohistochemical(IHC) staining. The detection of DOK3 and TAM was performed to quantify their expression level in two groups, respectively. The associations between the three mentioned biomarkers and clinicopathologic indicators were compared between the two groups, and the impact on patients' prognosis was also analyzed. R 4.2.2 software was used for data analysis. RESULTS: Death, late-stage cancer, T3-T4 and N(+) stage, large size (≥3 cm), moderate and poor differentiation, and recurrence exhibited significant associations with strong immunoexpression of P. gingivalis(P＜0.05). Several variables of OSCC patients with strong immunoexpression of P. gingivalis including age, survival status, T and N stage, recurrence exhibited significant associations with strong immunoexpression of DOK3 (P＜0.05); whereas T stage, clinical stage and tumor differentiation exhibited significant associations with strong immunoexpression of TAM (P＜0.05). Additionally, the immunoexpression of P. gingivalis was positively associated with the immunoexpression of DOK3 and TAM(P＜0.01). The prognosis of OSCC patients with strong positive expression of P. gingivalis, DOK3 and TAM was worse than that of patients with weak immunoexpression, respectively(P＜0.05). CONCLUSIONS: P. gingivalis is positively correlated with DOK3 and TAM. In addition, the strong immunoexpression levels of P. gingivalis, DOK3 and tumor-associated macrophage are associated with poor prognosis in patients with OSCC. Collectively, the mentioned three biomarkers can be considered as important indicators for evaluating clinical prognosis.
[Expression of LINC 00478 in oral squamous cell carcinoma and its effect on proliferation, migration and invasion].
Zhao Q, Han L, Zhao L … +3 more , Wang L, Zhuang L, Yuan R
Shanghai Kou Qiang Yi Xue · 2025 Apr · PMID 40550762
PUEPOSE: To examine the expression difference of LINC 00478 in oral squamous cell carcinoma (OSCC) and analyze its relationship with the prognosis of OSCC patients. To investigate the effects of LINC 00478 on proliferati...
PUEPOSE: To examine the expression difference of LINC 00478 in oral squamous cell carcinoma (OSCC) and analyze its relationship with the prognosis of OSCC patients. To investigate the effects of LINC 00478 on proliferation, migration, and invasion of OSCC cells, with the goal of offering a new potential approach for molecular detection and clinical diagnosis of OSCC. METHODS: Transcriptome data samples from OSCC were obtained from TCGA, and R software was utilized to assess the expression variance of LINC 00478 in OSCC tumor and normal tissues. Tissue samples from 26 OSCC patients, including cancer and adjacent tissues, were collected for RT-PCR analysis to determine the differential expression of LINC 00478 in OSCC tissues. In vitro experiments were conducted to explore the impact of LINC 00478 on proliferation, invasion, and migration of CAL27 cells. CCK-8 assay was used to observe the proliferation capability of LINC 00478 in CAL27 cells, while Transwell experiment was employed to assess its effects on cell migration and invasion. GraphPad Prism 8.0.2 software was used for statistical analysis of the data. RESULTS: Analysis of the TCGA database revealed that LINC 00478 was weakly expressed in OSCC tissues compared to adjacent normal tissues (P＜0.001), with high-expression LINC 00478 correlating with improved patient prognosis(P＜0.05). Furthermore, LINC 00478 was significantly under-expressed in 26 OSCC tissues (P＜0.001). Experimental data from CCK-8 assays indicated that upregulation of LINC 00478 suppressed CAL27 proliferation (P＜0.05). Additionally, Transwell experiments demonstrated that high-expression LINC 00478 significantly inhibited CAL27 migration and invasion (P＜0.05). CONCLUSIONS: LINC 00478 is significantly under-expressed in OSCC, and its high expression is positively correlated with a better prognosis. Over-expression of the LINC 00478 gene has been shown to inhibit the proliferation, migration, and invasion of CAL27 cells, suggesting a potential role in inhibiting cancer progression in OSCC.
[Segmentation and validation of mandibular canal and its bifurcation on cone beam CT based on deep learning].
Ye Y, Fang S, Lu H … +2 more , Liu M, Wu X
Shanghai Kou Qiang Yi Xue · 2025 Apr · PMID 40550761
PURPOSE: To train the U-net of convolutional neural network to establish a method for detecting and segmenting the mandibular canal and its bifurcation, and validate its accuracy based on the ground truth labeled by expe...
PURPOSE: To train the U-net of convolutional neural network to establish a method for detecting and segmenting the mandibular canal and its bifurcation, and validate its accuracy based on the ground truth labeled by experts. METHODS: A total of 290 CBCT scans were collected from Shanghai Stomatological Hospital from Jan. 2022 to Dec. 2022, which were divided into training set of 200 scans and test set of 90 scans. Model training included two steps. In the first step, bilateral mandibular canals and its bifurcation of 50 CBCT scans were labeled in 3D Slicer image computing platform by investigators. Three dimensional U-net segmentation model were trained initially with data enhancement. A morphological post-processing method was applied to the predicted results. In the second step, pseudo label method was employed to help annotating the mandibular canal and corresponding bifurcations on remaining 150 CBCTs, which would be included in training set after revision. Three dimensional U-net model was trained based on these 200 data. During test phase, totally 90 scans were labeled by two doctors and U-net model respectively. Consistency check was conducted to evaluate the labels between two doctors. Dice similarity coefficient and Hausdorff distance were calculated to evaluate the labels between doctors and the model. The detection rate of bifurcation was calculated. SPSS 20.0 software package was used for data analysis. RESULTS: In 90 CBCT test set, the Kappa value between two dentists' annotations was 0.667. The average Dice and Hausdorff distance between predictions and labels of doctors were (0.739±0.068) and (0.988±1.14) mm. In bifurcation detection, the detection rate was 91.30% on scans with clear bifurcations. CONCLSIONS: The dentification and segmentation U-net model of mandibular canal on dental CBCT can be reliable and practical for its high segmentation precision and predicting speed.
[A study on the effectiveness of different types of decalcifying solutions in the preparation of combined oral and maxillofacial tooth-mandibular-periodontal tissues].
Gu T, Wang M, Wang Y … +2 more , Li J, Zhang C
Shanghai Kou Qiang Yi Xue · 2025 Apr · PMID 40550760
PURPOSE: Comparative analysis of MORSE, formic acid and Plank-Rychlo decalcification solution for the treatment of combined tooth-mandibular-periodontal tissues to explore their application value. METHODS: Specimens incl...
PURPOSE: Comparative analysis of MORSE, formic acid and Plank-Rychlo decalcification solution for the treatment of combined tooth-mandibular-periodontal tissues to explore their application value. METHODS: Specimens including normal teeth, jaws and periodontal tissues discarded from Department of Oral Pathology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine were collected and randomly divided into 3 groups to analyse the differences in decalcification time, staining effect and nucleic acid integrity of 3 different decalcification solutions. SPSS 23.0 software package was used for statistical analysis. RESULTS: The mean decalcification time was 4.5, 3.5 and 3.6 days in the MORSE, formic acid and Plank-Rychlo group, respectively. H-E staining scores were in descending order in the MORSE, formic acid and Plank-Rychlo group. Immunohistochemical staining showed that AE1/AE3, p63 and Ki67 scores in MORSE group were better than those in the formic acid group and the Plank-Rychlo group, and Vimentin staining indices showed no significant difference between the 3 groups. In the fluorescence in situ hybridisation results, normal fluorescence signals were detected in 15 cases in MORSE group, 1 case in formic acid group and 4 cases in Plank-Rychlo group. The mean DNA concentration was 1.987, 1.963 and 1.115 ng/μL in MORSE, formic acid and Plank-Rychlo group, respectively; and the mean RNA concentration was 13.03, 11.08 and 1.66 ng/μL, respectively. There was no significant difference in DNA concentration and RNA concentration between MORSE and formic acid group(P＞0.05), and both DNA and RNA concentrations were higher in the 2 groups than those in Plank-Rychlo group(P＜0.001). CONCLUSIONS: MORSE decalcification solution has comprehensive advantages in the treatment of combined tooth-mandibular-periodontal tissues and is of value in the clinical, teaching and research aspects of pathology.
[Research progress and current situation of oral surgery robots based on published papers and patents analysis].
Zhang ZF, Shu ZQ, Xu F … +1 more , Shen HQ
Shanghai Kou Qiang Yi Xue · 2025 Feb · PMID 40275670
PURPOSE: To analyze the research progress and technological development of oral surgery robots, reveal the future development trend of oral surgery robots and put forward policy suggestions. METHODS: Focusing on the topi...
PURPOSE: To analyze the research progress and technological development of oral surgery robots, reveal the future development trend of oral surgery robots and put forward policy suggestions. METHODS: Focusing on the topic of oral surgery robots, literature review and patent data retrieval methods were used to analyze data from 2011 to 2023 from the perspectives of quantity, source, and technical field. RESULTS: The number of academic papers and patent applications in the field of oral surgery robots had explosive growth since 2015. The literature mainly focused on topics such as oral implantation and digitalization, with Chinese scholars publishing the most papers. The patents focused on tools such as models and instruments dedicated to oral surgery, as well as technical fields such as implant visual navigation and positioning systems. CONCLUSIONS: Oral surgery robots should be developed towards miniaturization and specialization in the future, and domestic breakthroughs in core technologies such as special instruments need to be accelerated.
[CBCT study on the measurement of occlusal plane and molars in adolescent patients with Class Ⅱ subdivision malocclusion].
Ding YF, Sun YY, Guo SY … +2 more , Li QQ, Song LJ
Shanghai Kou Qiang Yi Xue · 2025 Feb · PMID 40275669
PURPOSE: To study the CBCT imaging features of occlusal plane inclination, molar inclination, and molar height in adolescent patients with Class Ⅱ subdivision malocclusion, in order to provide reference for clinical diag...
PURPOSE: To study the CBCT imaging features of occlusal plane inclination, molar inclination, and molar height in adolescent patients with Class Ⅱ subdivision malocclusion, in order to provide reference for clinical diagnosis and treatment. METHODS: A total of 80 adolescent patients with malocclusion admitted to Suzhou Stomatological Hospital from January 2019 to December 2022 were selected, including 40 cases of Class Ⅱ subdivision malocclusion as the experimental group and 40 cases of Class Ⅰ malocclusion as the control group. The angles of the anterior, posterior and maxillary occlusal planes, as well as the inclination of the upper and lower molars in the mesial and distal direction, the inclination of the buccal and lingual direction, and the height of the molars were analyzed based on CBCT data. SPSS 23.0 software package was used for data analysis. RESULTS: There were significant differences in the angles of the neutral and distal anterior, posterior and maxillary occlusal planes, as well as the height of the upper and lower molars between the experimental group of patients with Class Ⅱ subdivision malocclusion(P＜0.05); There was no significant difference in the inclination of the upper and lower molars in the mesial and distal direction, as well as in the inclination of the buccal and lingual directions(P＞0.05). There was no significant difference in the comparison of left and right measurements in the control group(P＞0.05). The angles of the anterior, posterior and maxillary occlusal planes in the experimental group were significantly negatively correlated with the inclination of the maxillary molars in the mesiodistal and buccal lingual direction(P＜0.01), and negatively correlated with the height of the molars(P＜0.05). CONCLUSIONS: Patients with Class Ⅱ subdivision malocclusion may have differences in the angles of the posterior, anterior, and maxillary occlusal planes, as well as the height of the upper and lower molars, compared to Class Ⅰ malocclusion patients. In clinical orthodontic treatment, it is necessary to be vigilant for such patients, trying to choose appropriate treatment opportunities, and reasonable treatment plans to prevent malocclusion from developing towards a more severe direction.
[Comparison of the effect of A-PRF and CGF on the recovery of mandibular impacted third molar after extraction and on alveolar ridge of the adjacent second molar].
Pu LL, Chen CH, Tong X
Shanghai Kou Qiang Yi Xue · 2025 Feb · PMID 40275668
PURPOSE: To compare the recovery effect of advanced platelet-rich fibrin (A-PRF) and concentrated growth factor (CGF) in the treatment of mandibular impacted third molar(M3) extraction, and the effect on alveolar ridge o...
PURPOSE: To compare the recovery effect of advanced platelet-rich fibrin (A-PRF) and concentrated growth factor (CGF) in the treatment of mandibular impacted third molar(M3) extraction, and the effect on alveolar ridge of the adjacent second molar(M2). METHODS: A total of 150 patients who received mandibular impacted M3 extraction in Jinhua Central Hospital from September 2020 to August 2021 were included. Among them, group A (n=49) received conventional suture, group B (n=51)received conventional suture +A-PRF filling, and group C(n=50) received conventional suture +CGF filling. Postoperative clinical indexes, soft tissue healing, alveolar bone density changes and M2 alveolar ridge height changes were compared among the three groups. Meanwhile, complications and adverse reactions were recorded and compared among the three groups. SPSS 20.0 software package was used for data analysis. RESULTS: One week after surgery, the pain degree and swelling degree of the three groups were lower than before treatment(P＜0.05), and group B ＜ group C ＜ group A(P＜0.05). Mouth opening degree was higher than before treatment(P＜0.05), group B ＞ group C ＞ group A (P＜0.05), and the soft tissue healing condition of group B was better than that of group C, and than that of group A(P＜0.05). At 6 weeks and 12 weeks after surgery, the alveolar bone mineral density of the three groups was higher than that immediately after surgery(P＜0.05), and group B ＞ group C ＞ group A(P＜0.05). There were significant differences between group B and C at 6 weeks and 12 weeks after surgery (P＜0.05). The M2 alveolar ridge height (ΔH) 12 days after surgery was lower than that immediately after surgery(P＜0.05), and group B and C was lower than that of group A (P＜0.05). The incidence of complications such as bleeding, infection, dry socket, nerve injury and periodontal pus discharge in group B ＜ group C ＜ group A, and the incidence of complications was statistically significant(P＜0.05). CONCLUSIONS: The effects of A-PRF and CGF on M2 alveolar ridge and postoperative adverse reactions are similar, but A-PRF is better than CGF in improving clinical symptoms and promoting postoperative recovery in maxillary impacted M3 patients, with fewer complications, and is worthy of clinical promotion.
[Efficacy of total crown and porcelain inlay restoration and its effect on masticatory ability and gingival condition].
Wang M, Hou Y, Tian FF … +2 more , Meng DJ, Han S
Shanghai Kou Qiang Yi Xue · 2025 Feb · PMID 40275667
PURPOSE: To investigate the clinical efficacy of full crown and porcelain inlay in the treatment of cracked teeth after root canal treatment and repair and its effect on chewing ability and gingival status. METHODS: A pr...
PURPOSE: To investigate the clinical efficacy of full crown and porcelain inlay in the treatment of cracked teeth after root canal treatment and repair and its effect on chewing ability and gingival status. METHODS: A prospective study was conducted to select 106 patients with cracked teeth who underwent root canal treatment from December 2020 to December 2023, divided into experimental group and control group according to the random number table method, with 53 cases in each group. The clinical effects and adverse reactions of the two groups were counted and compared. The pain levels [visual analogue scale (VAS)] of the two groups before treatment,1 st, 3 rd and 7 th day after treatment were compared. The gingival conditions [plaque index (PLI), gingival index (GI), gingival bleeding index (BI) and periodontal pocket depth (PD)] were compared between the two groups before treatment and after 6 months of follow-up. The chewing ability (bite force, chewing efficiency) of the two groups before treatment, 1 month, 3 months and 6 months of follow-up were compared.Statistical analysis was performed with SPSS 25.0 software package. RESULTS: The good rate of the experimental group was higher than that of the control group, and the total incidence of adverse reactions was lower than that of the control group(P＜0.05). At the 1st, 3rd and 7th day after treatment, VAS scores of the two groups were significantly lower than those before treatment. The experimental group[(4.43±0.68), (3.15±0.63) and (2.04±0.51) points] were significantly lower than the control group[(4.86±0.57), (3.81±0.67) and (2.86±0.52) points], all showed a downward trend (P＜0.05). At 6 months of follow-up, BI and PD in the two groups were higher than those before treatment, GI and PLI were lower than those before treatment. GI, PLI, BI and PD in the experimental group were significantly lower than those in the control group(P＜0.05). After 1, 3 and 6 months of follow up, the masticatory efficiency and bite force of the two groups were higher than those before treatment. The masticatory efficiency of the experimental group was (70.25±5.57)%, (85.36±6.74)% and (92.57±6.35)%, which was significantly higher than that of the control group[(62.35±5.44)%, (73.57±6.32)% and (84.26±6.22)%]. The bite force in the experimental group[(112.52±9.67), (130.52±11.58) and (143.54±13.40) Ibs] were significantly higher than those in the control group[(98.53±9.47) , (113.25±10.54) and (125.36±12.46) Ibs], all of which showed an upward trend (P＜0.05). CONCLUSIONS: The clinical efficacy of porcelain inlays for cracked teeth after root canal treatment and repair is better than that of full crown repair, which can effectively improve the chewing ability and the gingival condition, the incidence of adverse reactions is low.
[Evaluation of the effect of chair side CAD/CAM all ceramic crowns for restoration of posterior tooth defects].
Zuo Y, Xu XB, Liu L … +1 more , Wang YT
Shanghai Kou Qiang Yi Xue · 2025 Feb · PMID 40275666
PURPOSE: To investigate the effect of chair side computer aided design/computer aided manufacturing (CAD/CAM) crown restoration technique in the treatment of posterior tooth defects and its influence on chewing ability....
PURPOSE: To investigate the effect of chair side computer aided design/computer aided manufacturing (CAD/CAM) crown restoration technique in the treatment of posterior tooth defects and its influence on chewing ability. METHODS: A total of 98 patients with posterior dental defects treated from June 2023 to May 2024 were selected and divided into control group (traditional silicone rubber impression crown repair) and experimental group (chair side CAD/CAM crown repair) according to different treatment methods. The repair effect, masticatory efficiency and bite force before and after treatment, periodontal index, complication rate and patient satisfaction were compared between the two groups. SPSS 22.0 software package was used for statistical analysis of the data. RESULTS: One month after treatment, there was no significant difference in comfort, edge fit, color matching and surface texture between the experimental group and the control group(P＞0.05). The experimental group was significantly better than the control group in adjacency contact, secondary caries prevention and gingival status (P＜0.05). After treatment,gingival index and plaque buildup, gingival sulcus bleeding index, the degree of gum health improvement of loose tooth in the experimental group were significantly better than in the control group(P＜0.05). There was no significant difference in the incidence of complications between the two groups after treatment(P＞0.05). Repair satisfaction of the experimental group was 96.15%, which was significantly higher than 86.96% of the control group(P＜0.05). CONCLUSIONS: Chair side CAD/CAM crown restoration technology has good application value in the treatment of patients with posterior dental defects, which can significantly improve the repair effect, improve chewing ability, effectively inhibit gingival inflammation and dental plaque generation, reduce the risk of gingival bleeding and tooth loosening, and significantly improve patients' satisfaction.
[Clinical application of prosthetic wall made by orthodontic band in vital pulp therapy of young permanent teeth].
Guo YT, Li H, Wu HB … +4 more , Teng Q, Liu YY, Wang S, Cai CY
Shanghai Kou Qiang Yi Xue · 2025 Feb · PMID 40275665
UNLABELLED: PURPOSE： To investigate the clinical application value of making false wall with orthodontic band when a large area of tissue defects of young permanent teeth is subgingival level and vital pulp therapy is r...
UNLABELLED: PURPOSE： To investigate the clinical application value of making false wall with orthodontic band when a large area of tissue defects of young permanent teeth is subgingival level and vital pulp therapy is required. METHODS: A total of 60 cases of young permanent molars with large tissue defects to subgingival level and requiring vital pulp therapy were selected and randomly divided into experimental group and control group, with 30 cases in each group. Orthodontic band was made in the experimental group, while traditional composite resin was used in the control group, rubber barrier was placed after the fabrication of the false wall. The clinical fabrication time, stability of the false wall after the use of rubber barrier and periodontal health conditions(SBI, GI, SPD) of the affected tooth before and after operation were compared between the two groups.Graph Pad Prism 5.0 software package was used for statistical analysis. RESULTS: The fabrication time of the experimental group was (6.01±0.34) min, which was shorter than that of the control group (12.02±0.53) min, and the difference was statistically significant(P＜0.05). But the stability of the false wall and the influence on the periodontal health of the affected teeth were not significantly different between the two groups(P＞0.05). CONCLUSIONS: For the cases of young permanent teeth with large area defects to subgingival and requiring vital pulp therapy, orthodontic band can shorten the fabrication time of false wall, provide relatively stable retention, with no significant effect on the periodontal status of the affected teeth in a short time. It can provide a new idea for the fabrication of false wall in pediatric dental clinical work.
[Abnormal characteristics of tongue consonants and their correlation with articulatory movement parameters in patients with tongue cancer after surgery].
Yuan F, Lu-Lu L, Liang YY … +5 more , Cao MM, Xu ZH, Qian CR, Wang D, Zhang K
Shanghai Kou Qiang Yi Xue · 2025 Feb · PMID 40275664
PURPOSE: To study the abnormal characteristics of tongue consonants and their correlation with articulatory movement parameters in patients with tongue cancer after operation. METHODS: A total of 119 patients with tongue...
PURPOSE: To study the abnormal characteristics of tongue consonants and their correlation with articulatory movement parameters in patients with tongue cancer after operation. METHODS: A total of 119 patients with tongue cancer who received surgical treatment at First Affiliated Hospital of Bengbu Medical University from March 2019 to May 2023 were selected. The patients were divided into tongue margin group(n=38), tongue body group (n=40) and tongue base group(n=41). Twenty-five monosyllabic words in Huang Zhaoming-Han Zhijuan Vocabulary List for evaluating tongue consonants were used as speech assessment tools to evaluate the errors of each tongue consonant. The articulation speech measurement and training instrument were used to extract the second formants (F2) of the /i/ and /u/ vowels of the patients by linear predictive spectrum, and the articulation movement parameters such as tongue distance and F2i/F2u were calculated according to the formula. SPSS 26.0 software package was used for data analysis. RESULTS: The rate of tongue consonant error in each group was as follows: in tongue margin group, preapical sound (49.5%)＞ apical middle sound (27.8%)＞ apical postapical sound (17.5%)＞lingual facial sound (9.4%)＞ lingual base sound (6.1%). In tongue body group, preapical sound (55.0%)＞ apical middle sound (47.1%) ＞ apical postapical sound (25.4%)＞lingual facial sound (12.1%)＞lingual base sound (3.3%). In tongue base group, preapical sound (60.0%)＞postapical sound (52.0%) ＞apical medium sound (51.9%)＞lingual base sound (44.3%)＞lingual facial sound (34.8%). The error frequency of tongue apex medium sound in tongue body group and tongue base group was significantly higher than that in tongue margin group, and the error frequency of tongue apex posterior sound, tongue surface sound and tongue base sound in tongue base group was significantly higher than that in tongue body group and tongue margin group(P＜0.05). Tongue distance and F2i/F2u in tongue base group were significantly lower than those in tongue margin group and tongue body group, and tongue distance and F2i/F2u in tongue body group were significantly lower than those in tongue margin group(P＜0.05). Tongue distance, F2i/F2u were significantly negatively correlated with the error frequency of apical midpoint, apical postpoint and base sound in all groups(r＜0, P＜0.05). CONCLUSIONS: Most patients with tongue cancer after operation have abnormal tongue tip, and the most serious problem is the pretip. In clinical practice, objective parameters such as tongue distance and F2i/F2u can be used to quantitatively and indirectly evaluate the articulation status and dynamic rehabilitation effect of tongue cancer patients after surgery.
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