Shanghai Kou Qiang Yi Xue = Shanghai Journal Of Stomatology[JOURNAL]
Sun
200 papers
[Respiratory sleep monitoring and sleep quality questionnaire survey of Class Ⅱ malocclusion adolescents before and after functional orthodontic treatment].
Xia WQ, Gao MQ, Gu XY … +1 more , Chen N
Shanghai Kou Qiang Yi Xue · 2024 Dec · PMID 40007296
PURPOSE: To compare the changes of sleep-breathing parameters and sleep quality before and after treatment of Class Ⅱ malocclusion in adolescents. METHODS: Forty-eight adolescent patients were selected for functional ort...
PURPOSE: To compare the changes of sleep-breathing parameters and sleep quality before and after treatment of Class Ⅱ malocclusion in adolescents. METHODS: Forty-eight adolescent patients were selected for functional orthodontic treatment. Portable sleep breathing monitor and Pittsburgh sleep quality index(PSQI) were used before treatment, 1 month and 10 months after treatment, in order to compare the results of apnea and hypopnea index(AHI), obstructive apnea index(OAI), central apnea index(CAI), number of hypoventilation (HI), oxygen reduction index (ODI), minimum oxygen index(LSpO) and sleep quality index. SPSS 16.0 software package was used for data analysis. RESULTS: After 1 month of functional appliance use, AHI, HI and ODI were significantly decreased than those before treatment, while LSpO was significantly increased (P＜0.01), but there was no significant difference in OAI and CAI (P＞0.05). AHI, OAI, CAI, HI, ODI and LSpO 10 months after treatment were significantly different from those before and 1 month after treatment(P＜0.01). The sleep duration, quality, efficiency, and sleep disturbance and daytime dysfunction were not different from one month than before treatment (P＞0.05), and related sleep quality scores were different from ten months after treatment compared with pre-treatment and one month after treatment(P＜0.01). AHI, OAI, HI, ODI and LSpO were positively correlated with sleep quality in patients(P＜0.01). CONCLUSIONS: Functional treatment of Class Ⅱ adolescents can improve sleep breathing situation and sleep quality of patients.
[Analysis of the diagnostic value of X-ray and CBCT 3D reconstruction in adolescent orthodontic patients with impacted teeth].
Gao LC, Ma YP, Gao LQ … +3 more , Liu DH, Wang C, Jia H
Shanghai Kou Qiang Yi Xue · 2024 Dec · PMID 40007295
PURPOSE: To evaluate the value of X-ray and cone-beam CT(CBCT) three-dimensional reconstruction in the diagnosis of impacted teeth in adolescent orthodontic patients. METHODS: From May 2021 to May 2024, totally 86 adoles...
PURPOSE: To evaluate the value of X-ray and cone-beam CT(CBCT) three-dimensional reconstruction in the diagnosis of impacted teeth in adolescent orthodontic patients. METHODS: From May 2021 to May 2024, totally 86 adolescent orthodontic patients with 126 impacted teeth admitted to the Second Hospital of Baoding City were selected for X-ray examination and CBCT 3D reconstruction. The diagnostic efficiency and accuracy of the two methods were evaluated by comparing their ability to reveal the location and adjacent anatomical structures of the impacted teeth. SPSS 26.0 software package was used for statistical analysis of the data. RESULTS: Among the 126 impacted teeth, totally 40 cases (52 teeth) were in the maxillary anterior tooth region, 8 in the maxillary posterior region (12 teeth), 12 with maxillary supernumerary teeth (20 teeth), 14 in the mandibular anterior region (22 teeth), 8 in the mandibular posterior region (14 teeth), and 4 with mandibular supernumerary teeth (6 teeth). The results of CBCT 3D reconstruction were close to operation findings. CBCT 3D reconstruction was superior to X-ray films in most indexes, especially in sensitivity and positive predictive value, showing higher diagnostic efficiency. CONCLUSIONS: CBCT three-dimensional reconstruction provides high diagnostic value in the diagnosis of impacted teeth in adolescent orthodontic patients, especially in accurately assessing the position of impacted teeth.
[Application of 3D printed double positioning guide in aesthetic restoration of anterior teeth].
Ren LJ, Liu JY, Li ZH … +3 more , Fang JY, Cui L, Wang ZH
Shanghai Kou Qiang Yi Xue · 2024 Dec · PMID 40007294
PURPOSE: To evaluate the clinical effect of 3D printing double positioning crown extension guide combined with 3D printing temporary crown in red aesthetic restoration of anterior teeth. METHODS: Twenty patients (70 teet...
PURPOSE: To evaluate the clinical effect of 3D printing double positioning crown extension guide combined with 3D printing temporary crown in red aesthetic restoration of anterior teeth. METHODS: Twenty patients (70 teeth in total) who needed aesthetic restoration were randomly divided into 3D printing group (9 cases, 36 teeth) and traditional restoration group (11 cases, 34 teeth). The 3D printing team performed digital design, 3D printing double positioning crown lengthening guide to help crown lengthening operation, and 3D printed temporary crown was used after operation. The traditional group underwent diagnostic wax design, traditional film compression to make crown extension guide, 3D printed temporary crown after crown extension, and scored at 1 month, 3 months and 6 months after wearing the temporary crown. The clinical effect was evaluated from papilla index score(PIS), pink esthetic score(PES), white esthetic score(WES) and patient satisfaction. SPSS 28.0 software package was used for statistical analysis of the data. RESULTS: The PIS score of the 3D printing group at 6 months was significantly better than that of the traditional restoration group(P＜0.05). The PES scores of 3D printing group at 1, 3 and 6 months were significantly higher than those of traditional restoration group(P＜0.05). WES scores at 1 month and 6 months in the 3D printing group were significantly higher than those in the traditional restoration group(P＜0.05). The overall satisfaction score of patients in the 3D printing group was higher than that in the traditional restoration group. CONCLUSIONS: The application of digital design, 3D printing double positioning crown extension guide and temporary crown to guide aesthetic crown lengthening and restoration of anterior teeth can improve the effect of aesthetic restoration and make patients have better aesthetic restoration experience.
[Comparison of adverse oral behaviors between patients with anterior disc displacement without reduction and healthy individuals].
Jiang X, Yang Y, Fang ZY … +3 more , Jin L, Xu LL, Yao Y
Shanghai Kou Qiang Yi Xue · 2024 Dec · PMID 40007293
PURPOSE: To explore the differences in adverse oral behavior between patients with anterior disc displacement without reduction(ADDWoR) and healthy individuals without temporomandibular disorders(TMD). METHODS: From Janu...
PURPOSE: To explore the differences in adverse oral behavior between patients with anterior disc displacement without reduction(ADDWoR) and healthy individuals without temporomandibular disorders(TMD). METHODS: From January to October 2023, a total of 170 patients with clinically confirmed ADDWoR were recruited from the Department of Rehabilitation Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, and 165 healthy subjects were recruited as controls during the same period. All subjects completed baseline data survey and Oral Behavior Checklist(OBC). The scores of each item and the total score of OBC were compared between the two groups. Logistic regression was used to analyze the relationship between oral behavior and ADDWoR. SPSS 23.0 software package was used for data analysis. RESULTS: The oral behavior scores of 16 items, sleeping oral behavior scores, waking oral behavior scores, and total OBC scores of the ADDWoR group were significantly higher than those of the healthy group(P＜0.05). Logistics regression analysis showed that the three behaviors of chin compression during sleep, teeth clenching and chin leaning forward or to one side when awake were risk factors for ADDWoR(P＜0.05). CONCLUSIONS: Compared with non-TMD healthy individuals, ADDWoR patients have a higher frequency of multiple adverse oral behaviors, among which, the occurrence of 3 behaviors (compression of the chin during sleep, gnashing of the teeth and leaning of the chin forward or to one side when awake) can increase the risk of ADDWoR.
[Effects of vestibular shield appliances on lip morphological changes in mouth breathing patients].
Ding QF, Nie P, You QL … +1 more , Xia YH
Shanghai Kou Qiang Yi Xue · 2024 Dec · PMID 40007292
PURPOSE: To evaluate the soft tissue position changes in the lower 1/3 of face after application of the vestibular shield for correction of mouth dyspnea. METHODS: A total of 32 pediatric patients wearing vestibular shie...
PURPOSE: To evaluate the soft tissue position changes in the lower 1/3 of face after application of the vestibular shield for correction of mouth dyspnea. METHODS: A total of 32 pediatric patients wearing vestibular shield appliances for mouth breathing correction were reviewed, and the changes of upper and lower lip positions as well as chin position before and after appliance treatment were compared and analysed. GraphPad Prism 6.0 software package was used for data analysis. RESULTS: The values of lateral protrusion N'-Sn-Pog' (facial convexity), nasolabial angle (Cm-Sn-Ls) lower lip protrusion (LL-EP) and upper lip prominence (UL-EP) were significantly reduced, of which UL-EP changes were the most obviously changed parameter. In addition, the chin morphology associated parameters Si-LiPg' and Sn-Gn'-C were significantly improved after treatment as well. No significant differences were observed within gender. CONCLUSIONS: Vestibular shield treatment for patients with mouth breathing can effectively improve the lip morphology.
[Clinical study of cervical lymph node metastasis in oral tongue squamous carcinoma by a machine learning model based on contrast-enhanced CT radiomics].
Sun HX, Zhu QH, Li HQ … +2 more , Wang CX, Ye JH
Shanghai Kou Qiang Yi Xue · 2024 Dec · PMID 40007291
PURPOSE: To investigate the value of machine learning model based on enhanced CT imaging features and clinical parameters in predicting cervical lymph node metastasis in patients with tongue squamous cell carcinoma (TSCC...
PURPOSE: To investigate the value of machine learning model based on enhanced CT imaging features and clinical parameters in predicting cervical lymph node metastasis in patients with tongue squamous cell carcinoma (TSCC). METHODS: A total of 75 patients with TSCC who were treated in the Affiliated Stomatology Hospital of Nanjing Medical University from January 2015 to July 2022 were collected. All patients had complete clinical data, enhanced CT image data and postoperative cervical lymph node pathological examination results. All cases were randomly assigned to the training group (n=60) and the validation group (n=15) in a ratio of 8∶2. A total of 1 833 radiomics features were extracted from the venous phase image data of enhanced CT. Correlation coefficient selection and LASSO method were used for feature selection and dimensionality reduction to select the optimal combination of radiomics features. Multiple machine learning algorithm models(LR, KNN, Random Forest, Extra Trees, XGBoost and LightGBM) were used to predict cervical lymph node metastasis on the selected radiomics and clinical features. The performance of the model was evaluated by receiver operating characteristic(ROC) curve and decision curve analysis(DCA). SPSS 21.0 software package was used for data analysis. RESULTS: After screening and dimensionality reduction, totally 14 optimal feature combinations were obtained, and a variety of prediction models were established based on them. Among them, the KNN model showed a more balanced fitting effect in the training group and the test group, with AUC values of 0.869 and 0.861, respectively. To further improve the efficiency of the model, we integrated imaging features with patient clinical features, and the AUC value of this comprehensive model was increased to 0.893 and 0.880 in the training group and the test group, respectively. The DCA decision curve showed that compared with the simple radiomic model, the image-clinical model with the integration of clinical features showed a higher predictive effect and clinical application value. CONCLUSIONS: The prediction model based on enhanced CT image omics features combined with clinical parameters can effectively estimate cervical lymph node metastasis in patients with TSCC. This approach facilitates risk stratification of patients with TSCC and optimizes clinical decisions to improve treatment strategies and patient outcomes.
[Screening of characteristic genes of salivary gland adenoid cystic carcinoma based on weighted co-expression network and machine learning].
Bu WC, Chen SX, Jiang YH … +4 more , Cao MG, Wu XR, Guan YQ, Xie SY
Shanghai Kou Qiang Yi Xue · 2024 Dec · PMID 40007290
PURPOSE: To identify potential biomarkers of salivary gland adenoid cystic carcinoma to further understand the potential pathogenesis of adenoid cystic carcinoma. METHODS: Two microarray datasets (GSE59701, GSE88804) wer...
PURPOSE: To identify potential biomarkers of salivary gland adenoid cystic carcinoma to further understand the potential pathogenesis of adenoid cystic carcinoma. METHODS: Two microarray datasets (GSE59701, GSE88804) were downloaded from NCBI GEO database. LIMMA software package was used to screen SACC differentially expressed genes. WGCNAs were used to find the important module genes that were most associated with SACC. Two machine learning methods(LASSO and SVM-RFE) were used to identify Hub genes. Subsequently, ROC curve used to predict SACC was developed to determine the diagnostic effect. R4.2.1 software was used for statistical analysis. RESULTS: Three hub genes(GABBR1, EN1 and LINC01296) were identified, and a ROC curve with high predictive performance (AUC, 1.000-1.000) was established. CONCLUSIONS: Three hub genes(GABBR1, EN1 and LINC01296) were obtained by WGCNA, LASSO, SVM-RFE as potential biomarkers of SACC, and the findings of this study provide a foothold for future research on potential key genes of SACC, and a target basis for the early diagnosis and treatment of SACC.
[The influence of different preset drill radius and tooth position on the compensation gap of zirconium dioxide restoration].
Guo YL, Peng JY, Qian DD … +2 more , Mei ZY, Meng XF
Shanghai Kou Qiang Yi Xue · 2024 Dec · PMID 40007289
PURPOSE: To explore the influence of different preset drill radius on the drill compensation space of zirconia dioxide restoration and the characteristics of tooth position and anatomical parts of the drill compensation...
PURPOSE: To explore the influence of different preset drill radius on the drill compensation space of zirconia dioxide restoration and the characteristics of tooth position and anatomical parts of the drill compensation space. METHODS: The digital design data of 12 cases of incisor, premolar and molar were randomly selected, and the radius of the needle was preset to 0.3, 0.4, 0.5 and 0.6 mm. Software analysis was performed to obtain four evaluation index values for each group of drill compensation gaps ,including compensation area, the proportion of the drillcompensation area to the preparation area, compensation volume and the maximum value of the compensation. The compensation frequency of the occlusal/incisal edge, axial surface and edge area of 0.5 mm preset radius group were recorded. Data were analyzed by two-way ANOVA and Chi-square test using SPSS 22.0 software package. RESULTS: The preset drill radius and tooth position significantly affect the values of the four evaluation indicators(P＜0.05) of the drill compensation space, among which the four evaluation index values were significantly reduced by the preset radius of the drill (P＜0.05). The probability that the maximum drill compensation thickness value of incisor and molar teeth in the 0.5 mm group and all types of teeth in the 0.6 mm group exceeded 300 μm existed, the frequency of 20 μm gap compensation in the incisor/occlusal edge area, the axial surface area, and the edge area of the preparation decreased in turn(P＜0.05). CONCLUSIONS: The preset radius of 0.3-0.4 mm can obtain a reasonable drill compensation gap on the tissue surface of the prosthesis. The occlusal/incisor area of the preparation needs to be carefully prepared to reduce the frequency of gap compensation.
[Analysis of hub genes, pathways and immune checkpoints of CD8+ T cells in metastatic lymph nodes of head and neck squamous cell carcinoma in C3H/He mice].
Zhou D, Han NN, Li HS … +2 more , Yan M, Ruan M
Shanghai Kou Qiang Yi Xue · 2024 Dec · PMID 40007288
PURPOSE: To explore the expression of hub genes, pathways and inhibitory immune checkpoints of CD8+ T cells in metastatic lymph nodes of head and neck squamous cell carcinoma(HNSCC) in C3H/He mice. METHODS: A popliteal l...
PURPOSE: To explore the expression of hub genes, pathways and inhibitory immune checkpoints of CD8+ T cells in metastatic lymph nodes of head and neck squamous cell carcinoma(HNSCC) in C3H/He mice. METHODS: A popliteal lymph node metastasis model of immunocompetent C3H/He mice was constructed with SCC-7 cell line of HNSCC, and the lymph node metastasis status was determined by immunofluorescence. CD8+ T cells in normal and metastatic lymph nodes were sorted by flow cytometry, and transcriptome sequencing analysis was performed to screen out differentially expressed genes. GO functional enrichment analysis and KEGG pathway enrichment analysis were performed sequentially. Flow cytometry and multiplex immunohistochemical were used to detect the expression of four immune checkpoints of CD8+ T cells in metastatic lymph nodes of tumor-bearing mice. SPSS 26.0 software package was used for statistical analysis. RESULTS: After 4 weeks of foot pad injection of SCC-7 cells, C3H/He mice displayed obvious metastasis in popliteal drainage lymph node. A total of 912 differentially expressed genes were screened out by transcriptome sequencing analysis of CD8+ T cells in normal and metastatic lymph nodes, including three inhibitory immune checkpoint-related genes which were upregulated(Pdcd1, Lag3 and Tigit). Eight tumor-related signaling pathways were screened out by KEGG network analysis, including Toll-like receptor signaling pathway, NF Kappa-B signaling pathway, TNF signaling pathway, MAPK signaling pathway, IL-17 signaling pathway, NOD-like receptor signaling pathway, PD-L1 and PD-1 immune checkpoint pathway in tumors and p53 signaling pathway. Flow cytometry showed high expression level of PD-1 and TIM-3 in CD8+ T cells in mouse metastatic lymph nodes. It was further confirmed by multiplex immunohistochemical that PD-1 was highly expressed in CD8+ T cells in metastatic lymph nodes of patients with HNSCC. CONCLUSIONS: Tumor-related signaling pathway of CD8+ T cells in mouse metastatic lymph nodes is significantly activated. The PD-1 expression level of CD8+ T in metastatic lymph nodes of mice and patients with HNSCC is markedly increased. Immunotherapy targeting CD8+ T cells may become a new strategy for the prevention and cure for lymph node metastasis of HNSCC.
[An in-vitro study to remove dental resin adhesive with ultrafast laser].
Yang XY, Zeng L, Ye SJ … +3 more , Zheng L, Gong Y, Wei B
Shanghai Kou Qiang Yi Xue · 2024 Dec · PMID 40007287
PURPOSE: To investigate the effect and safety of removing dental resin adhesive with ultrafast laser. METHODS: Resin adhesive layers were prepared on the surface of extracted teeth and processed with ultrafast laser scan...
PURPOSE: To investigate the effect and safety of removing dental resin adhesive with ultrafast laser. METHODS: Resin adhesive layers were prepared on the surface of extracted teeth and processed with ultrafast laser scanning. Morphology was observed under optical microscope and scanning electron microscope. Component change was tested with Raman Spectrometer and dental tissue damage was observed through sample sections. RESULTS: After laser processing, resin adhesive showed significant change in colour and volume expansion along with laser parameters. Dislodgement happened without any external force. Carbonization was presented in Raman spectroscopy result. No obvious damage was observed in enamel underneath. CONCLUSIONS: Ultrafast laser can be used to remove dental resin adhesives on the enamel.
[Molecular mechanisms of let-7c targeting IGF2BP2 to regulate the proliferation of human dental pulp stem cells].
Wang YS, Sun MX, Yang YC … +4 more , Heng X, Zhang YX, Yang JG, Liu Y
Shanghai Kou Qiang Yi Xue · 2024 Dec · PMID 40007286
PURPOSE: To investigate the effect and mechanism of let-7c overexpression on the proliferation of human dental pulp stem cells (hDPSCs). METHODS: hDPSCs were isolated and cultured. After transfected with let-7c mimics an...
PURPOSE: To investigate the effect and mechanism of let-7c overexpression on the proliferation of human dental pulp stem cells (hDPSCs). METHODS: hDPSCs were isolated and cultured. After transfected with let-7c mimics and inhibitors, transfection efficiency was detected by qRT-PCR, and cell proliferation was detected by cell counting kit-8 (CCK-8). Flow cytometry was applied to determine the cell cycle. The mechanism of let-7c inhibiting cell proliferation was analyzed by Western blot. A cell model targeting insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2) was constructed by transient transfection of small interfering RNA(siRNA) and analyzed by bioinformatics and dual luciferase reporter. Bioinformatics analysis and dual luciferase reporter gene assay were performed to investigate whether let-7c directly targeted IGF2BP2. The data were statistically analyzed using SPSS 17.0 software package. RESULTS: Overexpression of let-7c inhibited cell proliferation. Let-7c blocked cell proliferation by regulating the S and G2/M cycles, and directly bound to a group of messenger RNA (mRNA) sequences related to cell cycle regulation, IGF2BP2, and targeting and inhibiting IGF2BP2 expression, with a negative correlation between the two expression levels. CONCLUSIONS: let-7c inhibites the proliferation of hDPSCs by targeting and inhibiting IGF2BP2 expression.
[Differential miRNA profiling and target gene analysis of marrow mesenchymal stem cells in postmenopausal osteoporotic mouse mandibles].
Yang SS, Zhang W, Hu XH … +1 more , Yang XH
Shanghai Kou Qiang Yi Xue · 2024 Dec · PMID 40007285
PURPOSE: To explore the differential miRNA expression profiles and predicted target genes of mandibular bone marrow mesenchymal stem cells (MBMSCs) in a postmenopausal osteoporosis (POP) mouse model using bioinformatics...
PURPOSE: To explore the differential miRNA expression profiles and predicted target genes of mandibular bone marrow mesenchymal stem cells (MBMSCs) in a postmenopausal osteoporosis (POP) mouse model using bioinformatics methods, providing new targets for diagnosis, treatment, and prevention of POP. METHODS: POP mouse model was established by performing ovariectomy surgery, and MBMSCs were obtained using whole bone marrow adherent culture method. Microarray sequencing was performed to detect the miRNA expression profile of MBMSCs. Subsequently, miRNA identification and prediction analysis were conducted, along with the prediction of target genes. Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses, and protein-protein interaction (PPI) network analysis were performed on the predicted target genes. Key hub genes were identified using algorithms such as Degree, Betweenness, and Closeness. The data were analyzed by GraphPad Prism 8.0 and R language. RESULTS: A total of 84 differentially expressed miRNAs were obtained using a threshold of P＜0.05, with 33 upregulated and 51 downregulated miRNAs. GO and KEGG enrichment analyses of the 84 differentially expressed miRNAs revealed their involvement in various biological processes and pathways. Among them, 130 target gene mRNAs were enriched in the "regulation of stem cell pluripotency" signaling pathway. PPI network analysis and hub gene selection were performed for the 130 predicted target gene mRNAs, resulting in the identification of 7 reliable hub genes: Ctnnβ1, Hras, Kras, Akt1, Mapk3, Smad3, and Smad2. Among these hub genes, Ctnnβ1, Akt1, Mapk3, Smad3, and Smad2 were found to be significantly associated with POP. CONCLUSIONS: The differentially expressed miRNAs identified in MBMSCs of POP mice may serve as potential biomarkers and play important roles in the pathogenesis of POP. This study provides new research direction and theoretical basis for the diagnosis and treatment of POP.
[Evaluation of the preclinical teaching effects of digital virtual simulation system in veneer tooth preparation].
Qian YM, Zhang XY, Zhang H … +4 more , Ye RR, Zhou LY, Qi SC, Wang Y
Shanghai Kou Qiang Yi Xue · 2024 Oct · PMID 39719852
PURPOSE: To evaluate the preclinical teaching effects of digital virtual simulation system applied in window-type veneer tooth preparation of undergraduate dental students. METHODS: In the early clinical exposure of five...
PURPOSE: To evaluate the preclinical teaching effects of digital virtual simulation system applied in window-type veneer tooth preparation of undergraduate dental students. METHODS: In the early clinical exposure of five-year undergraduate students from School of Stomatology, Fudan University, Simodont virtual simulation system and conventional phantom-simulator system were alternatively used in the preclinical teaching of veneer tooth preparation. First, after theoretical training and tests of veneer tooth preparation, twenty-three students were randomly divided into two groups. Students in group of virtual simulation priority were trained using Simodont virtual simulation system, while those in group of phantom priority were trained using traditional phantom head to complete the window-type veneer tooth preparation within the specified time, followed by theoretical test again for all students. Then, the two groups of students exchanged training systems and completed the window-type veneer tooth preparation and assessment in the same time. All students were asked to fill up a teaching questionnaire for the evaluation of two training methods. The data were collected and analyzed using SPSS 21.0 software package. RESULTS: The scores of veneer preparations in labial surface cutting volume, labial surface form, cervical margin design, proximal margin design using traditional phantom head training system were significantly higher than those using Simodont virtual simulation system(P＜0.05). Statistical results showed that the scores of labial surface cutting volume of phantom priority group were significantly higher than those of virtual simulation priority group(P＜0.05), while the scores of incisal length of virtual simulation priority group were significantly higher than those of phantom priority group(P＜0.05). The results of the questionnaire showed that the majority of students believed that the traditional phantom head was more helpful than Simodont virtual simulation in identification of labial surface cutting volume, margin form, depth of indicator groove, cutting force, while Simodont virtual simulation was superior to traditional phantom head in safety and future development tendency. CONCLUSIONS: It is necessary to give full consideration of the advantages and limitations of digital virtual simulation system and design reasonable teaching plans. Combined application of digital virtual simulation system and traditional phantom head should be used to improve the preclinical teaching effects of veneer tooth preparation skills for undergraduate dental students.
[Application of mind mapping-assisted flipped classroom in clinical endodontics teaching].
Sun RN, Li XY, Fu YJ … +3 more , Jiang ZH, Zhang XH, Zhang Q
Shanghai Kou Qiang Yi Xue · 2024 Oct · PMID 39719851
PURPOSE: To explore the application effect of mind mapping-assisted flipped classroom in clinical endodontics teaching. METHODS: A total of 41 fifth-year undergraduates majoring in stomatology from School of Stomatology,...
PURPOSE: To explore the application effect of mind mapping-assisted flipped classroom in clinical endodontics teaching. METHODS: A total of 41 fifth-year undergraduates majoring in stomatology from School of Stomatology, Tongji University, finishing their clinical internship at Departments of Endodontics from October 2023 to March 2024, were randomly divided into control group (traditional teaching group, n=21) and experimental group (flipped classroom teaching group, n=20). Theoretical assessments were conducted on the day of entering the department and at the end of eight weeks in the department. Mini-CEX assessments were conducted in the third week and at the end of the eighth week (including indicators such as medical interviews, clinical examinations, humanistic care, clinical judgment, health education, clinical operations, and overall clinical capabilities). The scores of these two assessment indicators were used to evaluate the mastery extent of basic knowledge and clinical abilities of the two groups of students, and teaching satisfaction questionnaire survey was conducted. SPSS 22.0 software package was used for data analysis. RESULTS: In terms of theoretical assessment results, there was no significant difference between the two groups in the average scores of the first assessment. The average scores of both groups were better than those of the first assessment, and the average scores of the experimental group were significantly higher than those of the control group. In terms of mini-CEX assessment results, at the first assessment, the experimental group was better than the control group in two dimensions of clinical examination and clinical judgment, but there was no significant difference between the two groups in the other five dimensions. In the second assessment, the results of the two groups in 7 dimensions were higher than those of the first assessment, and the scores of the experimental group in 5 dimensions of medical interview, clinical examination, clinical judgment, clinical operation and overall clinical ability were significantly higher than those of the control group. CONCLUSIONS: Mind mapping-assisted flipped classroom teaching can significantly improve the subjective initiative of undergraduate students during clinical internships, enhancing their mastery extent of theoretical knowledge and overall clinical capabilities, and significantly improve the teaching effect.
[Analysis of the effect and influencing factors of glass fiber post and zirconia all ceramic crown in repairing tooth defects].
Lei YL, Jiang YP, Fang SR
Shanghai Kou Qiang Yi Xue · 2024 Oct · PMID 39719850
PURPOSE: To analyze the repair effect of glass fiber post combined with zirconia all ceramic crown in tooth defects and explore the relevant factors affecting the therapeutic effect. METHODS: A total of 100 patients(142...
PURPOSE: To analyze the repair effect of glass fiber post combined with zirconia all ceramic crown in tooth defects and explore the relevant factors affecting the therapeutic effect. METHODS: A total of 100 patients(142 teeth) with dental defects admitted to Shandong Provincial Chronic Disease Hospital from January 2018 to January 2021 were selected as the study subjects. They were divided into an experimental group (glass fiber post combined with zirconia all ceramic crown restoration) with 70 patients(98 teeth) and the control group (metal post combined with zirconium dioxide all ceramic crown) with 30 patients (44 teeth). Clinical follow-up was conducted 6 months after surgery to compare the differences in dental restoration effectiveness, gingival bleeding index (BI), plaque index (PLI), and probing depth (PD) between the two groups of patients. According to the 6-month postoperative repair effect of the experimental group, patients were divided into two groups: poor repair group and good repair group. Single factor and multi-factor analysis was used to analyze the factors affecting the repair effect of glass fiber post combined with zirconia all ceramic crown. Statistical analysis was performed with SPSS 22.0 software package. RESULTS: Six months after surgery, the proportion of grade A, grade B and grade C in the experimental group was 76.5%, 20.4% and 3.1%, respectively, while the control group was 50.0%, 40.0%, and 10.0%. The dental restoration effect in the experimental group was significantly better than that in the control group (P=0.008). Before surgery, there was no significant difference in BI, PLI and PD between the two groups of patients (P＞0.05). Six months after treatment, the BI, PLI and PD in the experimental group were significantly lower than those in the control group(P＜0.05). Compared with the group with good repair, the group with poor repair had a higher proportion of smoking and stepped broken end morphology (P＜0.05). Using smoking (yes=1, no=0) and broken end shape (step shape=1, blade shape=0) as independent variables, and efficacy (poor repair group=1, good repair group=0) as dependent variables, logistic regression analysis showed the factors that smoking and broken end shape affected the treatment efficacy(P＜0.05). CONCLUSIONS: Compared with metal post zirconium dioxide all ceramic crown restoration, glass fiber post combined with zirconium dioxide all ceramic crown restoration is more effective, but its restoration effect is affected by smoking and the shape of the broken end. Clinical intervention measures should be taken to improve the restoration effect.
[Correlation between inflammatory factors in gingival crevicular fluid and implant stability after oral implant restoration].
Qin K, Liu WJ, Li MQ … +1 more , Wang JL
Shanghai Kou Qiang Yi Xue · 2024 Oct · PMID 39719849
PURPOSE: To study the correlation between the levels of inflammatory factors in gingival crevicular fluid and implant stability and prognosis after oral implant restoration. METHODS: A total of 78 patients who underwent...
PURPOSE: To study the correlation between the levels of inflammatory factors in gingival crevicular fluid and implant stability and prognosis after oral implant restoration. METHODS: A total of 78 patients who underwent oral implant restoration surgery from August 2022 to August 2023 were selected as the experimental group. According to the results of X-ray examination 1 month after implantation, the patients were divided into poor prognosis subgroup(n=33) and good prognosis subgroup(n=45), another 60 healthy subjects who underwent physical examination during the same period were selected as the control group. The gingival crevicular fluid of all research subjects was collected, and chemiluminescent immunoassay was used to determine high-sensitivity C-reactive protein (hsCRP), and enzyme-linked immunosorbent assay was used to determine amyloid A(SAA) and procalcitonin (PCT), implant stability quotient(ISQ) was recorded after surgery. Pearson's correlation analysis was used to evaluate the correlation between inflammatory factors in gingival crevicular fluid and ISQ, and multifactor logistic regression analysis was used to analyze the relationship between inflammatory factors in gingival crevicular fluid and implant prognosis. Statistical analysis was performed with SPSS 22.0 software package. RESULTS: The levels of hsCRP, SAA and PCT in the gingival crevicular fluid of the experimental group were significantly higher than the control group(P＜0.05), the levels of hsCRP, SAA and PCT in the gingival crevicular fluid of the poor prognosis subgroup were significantly higher than the good prognosis subgroup (P＜0.05). The initial and second-stage ISQ values of the patients in the experimental group were (74.08±6.12) and (76.78±5.11) respectively. Pearson's correlation analysis results showed that the gingival crevicular fluid hsCRP, SAA and PCT were significantly negatively correlated with initial and second-stage ISQ(P＜0.05); multi-factor logistic regression analysis results showed that hsCRP, SAA and PCT in gingival crevicular fluid were important factors affecting the prognosis of patients with dental implants(P＜0.05). CONCLUSIONS: The levels of hsCRP, SAA and PCT in the gingival crevicular fluid after oral implant restoration are significantly increased, which are related to the stability and prognosis of the implant.
[Effects of personalized oral stents in intensity-modulated radiation therapy treatment].
Ye HF, Wang PL, Meng JQ … +1 more , Sun FF
Shanghai Kou Qiang Yi Xue · 2024 Oct · PMID 39719848
PURPOSE: To explore the effects of personalized oral stents in intensity-modulated radiation therapy (IMRT) treatment. METHODS: Totally 108 patients with nasopharyngeal carcinoma treated with IMRT at Nanjing Gaochun Peop...
PURPOSE: To explore the effects of personalized oral stents in intensity-modulated radiation therapy (IMRT) treatment. METHODS: Totally 108 patients with nasopharyngeal carcinoma treated with IMRT at Nanjing Gaochun People's Hospital from January 2021 to December 2023 were selected. Using a random number table method, the patients were divided into experimental group (n=54) using personalized oral stents and control group (n=54) using simple mouthpieces. The dosimetry of clinical target volumes (CTV), normal oral tissues, conformity index (CI), homogeneity index (HI), pain level evaluated by visual analogue scale(VAS ), grades of oral mucositis, xerostomia scores, taste scores, oral health impact profile (OHIP) scores and incidence of complications(dental caries, xerostomia, taste disorders, oral candidiasis, osteomyelitis of the jaw) were compared between the two groups. SPSS 23.0 software package was used for statistical analysis. RESULTS: There was no significant difference between the two groups in average received dose and CI, HI values on CTV and the tongue(P＞0.05); however, the experimental group showed a lower average received dose on the mandible, mandibular teeth, and bilateral parotid glands compared to the control group(P＜0.05). After treatment, the experimental group had significantly lower scores in VAS, grades of oral mucositis, xerostomia evaluation, OHIP and frequency of complications (P＜0.05). The taste scores in the experimental group were significantly higher than that in the control group (P＜0.05). CONCLUSIONS: Personalized oral stents significantly reduce the radiation dose to oral sites in IMRT treatment, decrease pain and other oral complications, and improve patients' quality of life.
[Analysis of root development of maxillary inverted impacted central incisor before and after orthodontic traction by CBCT].
Yan CJ, Zhang W, Chen ZF … +1 more , Wu JH
Shanghai Kou Qiang Yi Xue · 2024 Oct · PMID 39719847
PURPOSE: To investigate the changes of root development before and after orthodontic traction of maxillary inverted impacted central incisors using CBCT and Mimics software. METHODS: Ten patients, who had a maxillary inv...
PURPOSE: To investigate the changes of root development before and after orthodontic traction of maxillary inverted impacted central incisors using CBCT and Mimics software. METHODS: Ten patients, who had a maxillary inverted impacted central incisor, were treated using a modified movable retractor combined with surgical eruption. Cone-beam computed tomography(CBCT) was taken before and after treatment. Mimics 21.0 software was used to reconstruct the impacted central incisors (the impacted teeth group) and the contralateral namesake teeth (the contralateral group) before and after treatment, and the tooth volume and surface area were calculated by the software. SPSS 26.0 software package was used for paired t test, to evaluate the root development before and after treatment. RESULTS: All 10 patients were successfully treated,and the mean duration was (16.10±4.46) months. After treatment, the volume and surface area of teeth in the impacted teeth group were significantly increased compared with those before treatment(P＜0.01). The volume and surface area of the teeth before and after traction were significantly lower than those of the contralateral group(P＜0.01). However, during the treatment, there were no significant differences in the increase of tooth volume and surface area between the two groups(P＞0.05). CONCLUSIONS: Modified movable retractor combined with surgical eruption can promote root development of maxillary inverted impacted tooth, which is a safe and reliable treatment method.
[Application of periodontal microsurgery in periodontal accelerated osteogenic orthodontics].
Zhang JY, Liu N, Li JY … +1 more , Chen Y
Shanghai Kou Qiang Yi Xue · 2024 Oct · PMID 39719846
PURPOSE: To investigate the application value of periodontal microsurgery in accelerated osteogenic orthodontics (PAOO). METHODS: A total of 100 patients with the need of PAOO surgery before orthodontic treatment due to...
PURPOSE: To investigate the application value of periodontal microsurgery in accelerated osteogenic orthodontics (PAOO). METHODS: A total of 100 patients with the need of PAOO surgery before orthodontic treatment due to the lack of alveolar bone in the mandibular anterior area were selected and randomly divided into microsurgery group and control group with 50 cases in each group. Preoperative CBCT was used to measure the thickness and height of the alveolar bone as well as the gingival thickness. The gingival recession height was measured using periodontal probe. The pain level of the patients was evaluated immediately, 3, 7 and 14 days after surgery while the wound healing was recorded 14 days after surgery. The aforementioned indexes were recorded again 6 months after surgery. GraphPad Prism 5.0 software package was used for data analysis. RESULTS: The pain level of the microsurgery group were significantly lower than those of the control group at different time points after surgery. All the patients in the microsurgery group achieved healing by first intention 14 days after surgery. In addition, 6 months after surgery, the increase in alveolar bone thickness and the improvement of gingival recession in the microsurgery group were significantly better than those in the control group, thus achieving higher patient satisfaction. CONCLUSIONS: Periodontal microsurgery can facilitate the improvement of the surgical effect of PAOO, which has a promising value in the clinical application.
[Safety of closed traction appliance in the treatment of impacted anterior teeth and its effect on pulp blood flow and masticatory function].
Zhu Q, Zhao W, Wu HY
Shanghai Kou Qiang Yi Xue · 2024 Oct · PMID 39719845
PURPOSE: To analyze the safety of closed traction appliance in the treatment of impacted anterior teeth and its effect on pulp blood flow and masticatory function. METHODS: A total of 80 patients with impacted anterior t...
PURPOSE: To analyze the safety of closed traction appliance in the treatment of impacted anterior teeth and its effect on pulp blood flow and masticatory function. METHODS: A total of 80 patients with impacted anterior teeth who received treatment from January 2017 to December 2022 were selected, and randomly divided into experimental group and control group with 40 cases in each group. The two groups of patients were treated with occlusion adjustment and orthodontic traction. Closed traction was used in the experimental group, while open traction was used in the control group. The clinical efficacy, treatment duration, chewing ability, root length, periroot bone density, dental aesthetic score, pulp blood flow at different time points and the occurrence of adverse events were compared between the two groups. Statistical analysis was performed with SPSS 22.0 software package. RESULTS: The total effective rate was 95.00% in the experimental group and 90.00% in the control group, with no significant difference(P＞0.05). There was significant difference in traction eruption time and orthodontic time between the two groups(P＜0.05). There were significant differences in masticatory efficiency, bite force and masticatory pain score between the two groups before and after treatment(P＜0.05). There was no significant difference in root length and periroot bone density between the two groups before and after treatment(P＞0.05). There was no significant difference in white aesthetic score between the two groups before and after treatment(P＞ 0.05), but there was significant difference in red aesthetic score between the two groups before and after treatment(P＜0.05). There was no significant difference in pulp blood flow between the two groups at each time point(P＞0.05). At T1, the pulp blood flow reached its peak higher than T0; at T2, it rapidly decreased below T1 but higher than T0; at T3, it gradually decreased below T1 and T2 but higher than T0(P＜0.05). The incidence of adverse events in the experimental group was 10.00% compared with 27.50% in the control group, and the difference was statistically significant(P＜0.05). CONCLUSIONS: Both closed traction and open traction correction can effectively treat the impacted anterior teeth, and the two methods have no significant effects on root length, surrounding bone density and pulp blood flow. Although the treatment time of closed traction is slightly longer, it is more beneficial to improve patients' masticatory ability, and has high aesthetics and safety, which is worthy of clinical promotion.
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