Kudaeva IV, Masnavieva LB, D'yakovich OA
… +3 more, Beygel EA, Shayahmetov SF, Avramenko KA
Med Tr Prom Ekol
· 2017 · PMID 30351651
The article presents results of study concerning biochemical markers of endothelial dysfunction and structural changes in cardiovascular system of aluminium production workers with initial and advanced symptoms of occupa...The article presents results of study concerning biochemical markers of endothelial dysfunction and structural changes in cardiovascular system of aluminium production workers with initial and advanced symptoms of occupationally related bronchopulmonary diseases. Common pathogenetic traits of cardiovascular diseases with initial and advanced symptoms of occupationally related bronchopulmonary diseases are disordered regulation of vascular tone due to nitrogen and plasmin, atherosclerotic plaques formation and changed cardiomyocytes function. Individuals with initial symptoms of occupationally related bronchopulmonary diseases are characterized by increased cardiomyocytes apoptosis due to circulatory disorders. Mechanisms of cardiovascular diseases for advanced symptoms of occupationally related bronchopulmonary diseases are related to disordered regulation of cellular hemostasis by nitrogen oxide and plasmin, changed regulation via b-adrenoreceptors and altered cardiomyocytes metabolism.
Comparative evaluation covered work conditions in contemporary sulphate cellulose productions with various levels of mechanization and automation. Findings are that major work hazards for cellulose production workers are...Comparative evaluation covered work conditions in contemporary sulphate cellulose productions with various levels of mechanization and automation. Findings are that major work hazards for cellulose production workers are: polluted workplace air with chemical complex (methylsulphurous compounds, chlorine, chlorine dioxide, alkaline aerosol) in concentrations exceeding MAC, heating microclimate, noise. Levels of workplace air pollution with chemical hazards and transitory disablement morbidity parameters are considerably lower in highly automated production.
The article presents information on activities of International Committee on Occupational medicine - history of its foundation, development and formation, main scientific goals and studies.The article presents information on activities of International Committee on Occupational medicine - history of its foundation, development and formation, main scientific goals and studies.
In search of inflammatory molecular markers helpful in detection of increased risk and prognosis of severity of syntropic occupational bronchial asthma and metabolic syndrome, the authors conducted a study covering 140 e...In search of inflammatory molecular markers helpful in detection of increased risk and prognosis of severity of syntropic occupational bronchial asthma and metabolic syndrome, the authors conducted a study covering 140 examinees with confirmed occupational bronchial asthma. According to IDF criteria (2005), the patients were assigned into a group with combined occupational bronchial asthma and metabolic syndrome, and a group of occupational bronchial asthma without metabolic syndrome. All the examinees underwent studies of inflammation markers - biochemical (C-reactive protein, leptine) and molecular-genetic ( polymorphism of Gln223Arg gene of leptine receptor (LEPR), polymorphism of C174G gene of interleukin-6 (IL-6), polymorphism of G308A gene of (TNF-a) tumor necrosis factor alpha). Evidences are that the patients with combined bronchial asthma and metabolic syndrome demonstrate higher activity of inflammatory processes (higher level of C-reactive protein, leptine) - that manifests in clinically more severe course of bronchopulmonary disease. Moleculary-genetic markers revealed are associated with higher activity of inflammation and therefore with increased risk of occupational bronchial asthma associated with metabolic syndrome and diabetess mellitus 2 type (polymorphisms of LEPR gene, IL-6 gene).
The studies revealed that work of paramedical personnel can be assigned to 2 jeopardy class in chemical factor, noise, vibration, illumination, work hardiness; in unfavorable parameters of microclimate in summer period a...The studies revealed that work of paramedical personnel can be assigned to 2 jeopardy class in chemical factor, noise, vibration, illumination, work hardiness; in unfavorable parameters of microclimate in summer period and work intensity - to 3.1 class, in biologic factor - to 3.1-3.3 class. According to totality of factors, the work of paramedical personnel corresponds to 3.2-3.3 class of work conditions. Morbidity level of medical nurses is <<very low>> with minimal level of occupational risk. With that, more detailed analysis in 4 length of service groups revealed that in a group with over 15 years of service the morbidity level reaches high and extremely high (from 104.0 to 244.4 cases per 100 medical staffers). This evidence could be explained by exposure to occupational risk factors and worse health state with longer length of service and ageing.
Search in electronic resource ProQuest Dissertations and Theses (PQDT) found 12,813 dissertation works in hygiene, prepared in foreign universities in 1992-2015. Master's degree dissertations were 99.4%, doctor's degree...Search in electronic resource ProQuest Dissertations and Theses (PQDT) found 12,813 dissertation works in hygiene, prepared in foreign universities in 1992-2015. Master's degree dissertations were 99.4%, doctor's degree - 0.6%, published in English - 97.2%. In US universities were prepared 67.7% of the works, in Canada - 30.9%, in other countries - 1.4%. No Russian dissertations were found in PQDT. General hygiene topics were studied in 27.5% of the works, communal hygiene - in 5.3%, industrial hygiene and occupational diseases - in 7%, pediatric hygiene - in 20%, nutrition hygiene - in 17.8%, radiation hygiene - in 0.7%, rural hygiene - in 12.5%, hospital hygiene - in 8.3%, military hygiene - in 0.9%. Electronic resource PQDT opens wide possibilities for scientists - 89.9% dissertations in hygiene contained complete texts.
The article presents results of study concerning relationship of educational conditions and health state of high education students in 3 institutes of Voronezh city. Subjective self-assessment of health covered first 3 y...The article presents results of study concerning relationship of educational conditions and health state of high education students in 3 institutes of Voronezh city. Subjective self-assessment of health covered first 3 years students of Voronezh State Medical university (VSMU), Voronezh State university of engineering technologies (VSUET) and Voronezh State Construction university (VSCU). Health worsening was seen in 50,2% of VSMU students, in 28,7% of VSUET students and in 23,9% of VSCU examinees since beginning of the high education, and revealed breach of legislation concerning requirements of high education conditions are nearly identical.
Styopkin YI, Mekhant'ev II, Platunin AV
… +1 more, Kolnet IV
Med Tr Prom Ekol
· 2016 Sep · PMID 30351644
The article presents studies evaluating influence of chemical and noise exposure on public health in municipal district of Voronizh city, based on risk evaluation methodology. Comparative analysis covered levels of carci...The article presents studies evaluating influence of chemical and noise exposure on public health in municipal district of Voronizh city, based on risk evaluation methodology. Comparative analysis covered levels of carcinogenic, non-carcinogenic and normalized risks in monitoring control sites of the district. The studies revealed <<risky>> territories within the city, defined critical organs and systems under unfavorable influence by studied environmental factors.
Findings are that major occupational risk factors of morbidity among hothouse female workers are unfavorable microclimate parameters: in hothouses for vegetables growing - high air temperature, high relateive humidity hi...Findings are that major occupational risk factors of morbidity among hothouse female workers are unfavorable microclimate parameters: in hothouses for vegetables growing - high air temperature, high relateive humidity high air motion speed in summer; in hothouses for mushrooms growing - high humidity forced posture work. In occupational morbidity structure of hothouse female workers, the major place is occupied by acute respiratory viral infections, respiratory diseases (20.6%) and locomotory diseases (7.9%).
Mekhant'ev II, Styopkin YI, Platunin AV
… +2 more, Kameneva OV, Kamenev VI
Med Tr Prom Ekol
· 2016 Sep · PMID 30351642
Physiologic and hygienic evaluation covered work conditions on small business enterprises of retail and minor wholesale trade. Major unfavorable occupational factor for minor retail seller of foods is work process hardin...Physiologic and hygienic evaluation covered work conditions on small business enterprises of retail and minor wholesale trade. Major unfavorable occupational factor for minor retail seller of foods is work process hardiness (up to 85% of <<standing>>). This work affects the workers' state, with 100% reports of the health state changes by the end of the working day. Physiologic parameter <<work process hardiness>> in the trade workers generally was assigned to allowable (2 grade) criterion, but such parameters as work contents (work covers solving complicated problems), work in tight time conditions, responsibility and long working hours are assigned to first jeopardy degree (3.1). Minor retail trade enterprises appeared to have no work and rest schedule, that is an additional risk factor. Microclimate parameters inside the rooms are the same as outdoors, therefore necessity is to provide artificial sanitary technical systems of ventilation and heating in projects of minor retail trade networks.
Dulova NA, Batishcheva GA, Klepikov OV
… +1 more, Samodurova NY
Med Tr Prom Ekol
· 2016 Sep · PMID 30351641
Tests helped to evaluate psychoneurologic state in civil aviation pilots with various stages and grades of essential hypertension. Findings are that increase of essential hypertension intensity from borderline stage to 1...Tests helped to evaluate psychoneurologic state in civil aviation pilots with various stages and grades of essential hypertension. Findings are that increase of essential hypertension intensity from borderline stage to 1 stage 2 grade reliably influences psychoneurologic state of pilots. Worsening was seen for parameters of volitional attention and spatial representation (test <<Landolt rings>>), ability to operate spatiel representations (test <<Compasses>>), ability to extrapolate, rapid sensomotor reaction (test <<Labyrinth>>), accuracy of dynamic eye assessment and balance of main nervous processes in visual analyzer (test <<Reaction to moving object>>). Essential hypertension groups demonstrated dependence of the test results on age. Essential hypertension lowers parameters of the tests restults - that characterizes psychoneurologic state of pilots.
The study covered health state of medical personnel exposed to magnetic field in MRI-tomography offices. Findings are changes in functioning of cardiovascular and central nervous systems in a personnel group working with...The study covered health state of medical personnel exposed to magnetic field in MRI-tomography offices. Findings are changes in functioning of cardiovascular and central nervous systems in a personnel group working with tomographs, that prove tension of adaptation processes due to occupational factors.
Analysis of health state in connection with work conditions for workers of Voronezh tire plant was based on evaluation of occupational and general morbidity according to medical examination data, hygienic characteristics...Analysis of health state in connection with work conditions for workers of Voronezh tire plant was based on evaluation of occupational and general morbidity according to medical examination data, hygienic characteristics of occupational factors and working process. Findings are high level of general morbidity among the workers, related to combined influence of physical and chemical occupational hazards. First rank places are occupied by locomotory system diseases (32.3%) and cardiovascular diseases (29.3%). Recommendations cover decrease of unfavorable effects of occupational hazards, minimization of occupational risks, including further improvement of work conditions and implementation of laboratory biochemical methods diagnosing premorbid conditions.
Esaulenko IE, Petrova TN, Kolesnikova EN
… +1 more, Gubina OI
Med Tr Prom Ekol
· 2016 Sep · PMID 30351638
The article presents results of occupational morbidity analysis in a region, with assessment of trends, levels, dynamics and structure of morbidity, factor dependency of occupational diseases, identification of occupatio...The article presents results of occupational morbidity analysis in a region, with assessment of trends, levels, dynamics and structure of morbidity, factor dependency of occupational diseases, identification of occupational conditions of its occurrence. The information obtained helped to specify a system of occupational risk management, that increases efficiency in solving problems and better work safety in production.
The article covers historical materials about Russian scientists Vladimir Vladimirovitch Svyatlovsky, author of the first Russian manual on industrial medicine - <<Factory hygiene>>. Role of the scientist in national sci...The article covers historical materials about Russian scientists Vladimir Vladimirovitch Svyatlovsky, author of the first Russian manual on industrial medicine - <<Factory hygiene>>. Role of the scientist in national science development, his contribution into workers' health preservation, his works and lectures - these are topics also covered in the article.
The article presents results on experimental modelling an influence of silver nanoparticles incorporated into natural polymer arabinogalactane matrix on brain tissue of white outbred rats. The rats underwent parenteral i...The article presents results on experimental modelling an influence of silver nanoparticles incorporated into natural polymer arabinogalactane matrix on brain tissue of white outbred rats. The rats underwent parenteral injection of silver nanoparticles incorporated into polymer arabinogalactane matrix (dosage of 100 and 500 micrograms of silver per kg of the animal weight). The studies covered expression of 2 proteins participating in apoptosis process, in mitochondrial activation type - caspase-3 and protein bcl-2. During experiment, the groups examined demonstrated significant dose-dependent effect of bcl- 2 protein expression and increased number of caspase-3 expressed and non-expressed hyperchromic cells under exposure to argentumarabinogalactane - that indicates disorders of cellular structure and apoptosis development.
The article presents results of evaluating chronic intoxication risks, acute toxic effects risk, carcinogenic risk and risk of occupational diseases due to dust. Findings are that the highest risk levels for chronic into...The article presents results of evaluating chronic intoxication risks, acute toxic effects risk, carcinogenic risk and risk of occupational diseases due to dust. Findings are that the highest risk levels for chronic intoxication and carciongenic risk are seen in coal open cast miners. The most dangerous occupation is diesel locomotive operator. High risk of occupational disease due to dust is seen in electric steel-making, rail and structural steel production. The most dangerous occupations are electric furnace melters, melter assistants, crane operators, hot rolling operators, metal heaters. The authors revealed chemicall pollutants making maximal contribution into formation of health risk for workers.
Experimental studies covered risk of possible toxic influence by medications - derivatives of 1.4-benzodiazepine - in single and multiple intake by intragastric way, inhalation and skin application. The authors give reco...Experimental studies covered risk of possible toxic influence by medications - derivatives of 1.4-benzodiazepine - in single and multiple intake by intragastric way, inhalation and skin application. The authors give recommendations on hygienic regulation of 1.4-benzodiazepine derivatives - alprazolam, diazepam, mezapam and nozepam. The study results served as a base for specifying approximate safe level of exposure to alprazolam at level of 0.1 mg/m³, diazepam - 0.2 mg/m³, mezapam - 0.3 mg/m³ and nozepam at level of 1.0 mg/m³ in the air of workplace.
The authors analyzed changes of statistic, spectral and non-linear parameters of cardiac rhythm variability in response to active orthostasis test in young individuals engaged into manual work, and the results are compar...The authors analyzed changes of statistic, spectral and non-linear parameters of cardiac rhythm variability in response to active orthostasis test in young individuals engaged into manual work, and the results are compared with hemodynamic parameters. Evidence is that the patients with neurogenous fainting present sympathetic vasomotory regulation disorders even in young age; before clinical manifestation as orthostatic hypotension. In comparison with common tilt-test, spectral analysis of cardiac rhythm variability in active orthostatic test can be more useful to reveal early disorders of autonomous regulation.
Mining industry is characterized by hazardous work conditions that determine high risk of occupational morbidity. The article presents results of hygienic evaluation of work conditions and health risk for workers of Tash...Mining industry is characterized by hazardous work conditions that determine high risk of occupational morbidity. The article presents results of hygienic evaluation of work conditions and health risk for workers of Tashtagolsk mining enterprise in Kemerovo region, due to exposure to occupational hazards: noise, dust level, toxic chemicals. The authors present structure of occupational groups in mining industry, based on values of occupational factors, and taxonomic index characterizing overall risk level connected with occupational hazards.