PURPOSE: s:Radical prostatectomy threatens masculine identity, worsening anxiety, depression, and quality of life. No validated Chinese tool exists. This study translates and culturally adapts the Masculinity in Chronic...PURPOSE: s:Radical prostatectomy threatens masculine identity, worsening anxiety, depression, and quality of life. No validated Chinese tool exists. This study translates and culturally adapts the Masculinity in Chronic Disease Scale and evaluates its psychometric properties in Chinese prostate cancer patients. METHODS: Following Brislin's translation model, the MCD-I was translated, back-translated, and culturally adapted to develop a Chinese version. A convenience sample of 372 prostate cancer patients was recruited from four hospitals in Henan Province between January 2024 and August 2025. Psychometric evaluation included internal consistency, test-retest reliability, exploratory factor analysis (EFA), and confirmatory factor analysis (CFA). RESULTS: The Chinese version of the MCD-I demonstrated strong internal consistency (Cronbach's α = 0.903). Subscale α coefficients were 0.894, 0.815, 0.844, 0.649, and 0.872. Test-retest reliability was high, with a significant intraclass correlation coefficient ICC = 0.956 (95% CI: 0.924-0.975). EFA extracted five factors, accounting for 75.10% of the variance. CFA confirmed acceptable model fit (RMSEA = 0.070, CMIN/DF = 1.915, CFI = 0.910, GFI = 0.861, IFI = 0.911). Spousal accompaniment, educational attainment, medical insurance type, perceived stress, self-esteem, and perceived social support were all significantly associated with masculinity (P < 0.001). CONCLUSION: The Chinese version of the MCD-I shows satisfactory reliability and validity, and represents a reliable tool for assessing masculinity. Identifying the factors influencing masculinity in patients after radical prostatectomy can provide a theoretical basis for developing gender-sensitive psychosocial services and programs for men with prostate cancer.
PURPOSE: To examine the co-occurrence of social isolation and loneliness among colorectal cancer patients with a permanent stoma and its associated factors based on the ICF framework. METHODS: A convenience sample of 469...PURPOSE: To examine the co-occurrence of social isolation and loneliness among colorectal cancer patients with a permanent stoma and its associated factors based on the ICF framework. METHODS: A convenience sample of 469 patients was recruited from three tertiary Grade A hospitals in Shandong Province between November 2023 and December 2024. Data were collected using questionnaires on demographics, social isolation, loneliness, social participation, stigma, motivation for social connectedness, and family functioning. Multinomial logistic regression was used to identify factors associated with the co-occurrence patterns of social isolation and loneliness. RESULTS: Social isolation and loneliness were reported by 59.2% and 47.8% of patients, respectively. Four co-occurrence patterns were identified: no social isolation and no loneliness (Class 1, 28.3%), social isolation but no loneliness (Class 2, 23.9%), no social isolation but loneliness (Class 3, 12.4%), and both social isolation and loneliness (Class 4, 35.4%). Higher social participation was associated with lower odds of belonging to all three vulnerable groups. Greater stigma increased the likelihood of belonging to the no social isolation but loneliness and coexistence groups. Higher motivation for social connection reduced the likelihood of belonging to the social isolation but no loneliness and coexistence groups. Better family functioning was associated with lower odds of belonging to the no social isolation but loneliness and coexistence groups. CONCLUSION: Coexisting social isolation and loneliness was the most common pattern. The findings suggest that future assessment and supportive care should consider the heterogeneity of social isolation-loneliness patterns, with attention to social participation, stigma, motivation for social connectedness, and family functioning.
PURPOSE: To (1) assess the adequacy of cancer-related pain management among hospitalized adult patients with cancer in Oman and (2) examine the association between pain-management adequacy and psychological distress. MET...PURPOSE: To (1) assess the adequacy of cancer-related pain management among hospitalized adult patients with cancer in Oman and (2) examine the association between pain-management adequacy and psychological distress. METHODS: A descriptive, correlational, cross-sectional design was used with a convenience sample of 202 in-patients with cancer recruited from two tertiary oncology centers in Oman between June and September 2024. Cancer-related pain management was evaluated using the Pain Management Index (PMI), which compares the potency of prescribed analgesics, based on the World Health Organization analgesic ladder, with patients' reported worst pain intensity. Pain intensity and interference were measured with the Brief Pain Inventory-Short Form, and anxiety and depression with the Hospital Anxiety and Depression Scale. Logistic regression was used to identify predictors of inadequate pain management (PMI <0). RESULTS: Pain, anxiety, and depression prevalences were high, and the mean PMI score suggested overall inadequate pain management. Pain most commonly interfered with sleep, normal work, and general activity. Longer time since diagnosis was associated with higher odds of adequate pain management, whereas greater interference in relations with other people was associated with lower odds. Adequacy of pain management showed a weak negative association with anxiety and no significant association with depression. CONCLUSIONS: Among hospitalized patients with cancer in Oman, cancer-related pain was highly prevalent and undertreated, in the context of psychological distress. Holistic, culturally sensitive interventions that optimize analgesic prescribing while concurrently addressing anxiety, depression, and social relationships are needed to improve pain control, quality of life, and overall well-being in this population.
PURPOSE: Psychosocial challenges of living with metastatic breast cancer are well documented for patients, but less is known about their impact on families. Understanding family perspectives and existing support interven...PURPOSE: Psychosocial challenges of living with metastatic breast cancer are well documented for patients, but less is known about their impact on families. Understanding family perspectives and existing support interventions is essential to strengthen care for families. This scoping review aimed to map psychosocial experiences of patients with metastatic breast cancer and their families and to identify existing family support interventions. METHOD: Following Joanna Briggs Institute guidance and PRISMA-ScR standards, a comprehensive search was conducted in MEDLINE, CINAHL, Embase, PsycINFO, and Scopus, supplemented by grey literature. The final search was performed in November 2025. Two reviewers independently screened titles/abstracts and full texts. Data were synthesised narratively using reflexive thematic analysis. RESULTS: A total of 56 studies were included. 46 studies described psychosocial experiences, highlighting substantial emotional, relational, and practical challenges affecting patients and families across the MBC trajectory. Four themes emerged: Managing psychosocial and emotional challenges; Navigating family relationships and communication; Adapting to role changes and practical burdens in the family; and Seeking support and coping with end-of-life challenges. Ten studies reported support interventions, which were few, heterogeneous, and mainly showed short-term or feasibility outcomes. No studies were identified that examined families' experiences of routine disease monitoring. CONCLUSIONS: Families experience complex and evolving psychosocial challenges, while existing family support interventions remain limited and do not reflect the changing needs of families. The absence of research on routine disease monitoring represents a critical gap. Future research should inform the development of flexible, family-oriented support interventions aligned with changing needs over time.
PURPOSE: Physical inactivity is prevalent among colorectal cancer (CRC) survivors and is associated with adverse health and rehabilitation outcomes. However, theory-driven interventions to promote physical activity (PA)...PURPOSE: Physical inactivity is prevalent among colorectal cancer (CRC) survivors and is associated with adverse health and rehabilitation outcomes. However, theory-driven interventions to promote physical activity (PA) in this population remain scarce. This study aimed to evaluate the feasibility and acceptability of a PA intervention program guided by the Capability-Opportunity-Motivation-Behavior (COM-B) model in CRC survivors, and to explore its preliminary effectiveness. METHODS: A single-arm pre-post pilot study was conducted with 28 CRC survivors at a tertiary hospital in Wuxi, China. A 12-week COM-B model-guided PA intervention was implemented between March and June 2025. Feasibility was assessed via recruitment and retention rates. Acceptability was evaluated using a mixed-methods approach combining self-report questionnaires with semi-structured interviews; qualitative data were analyzed through content analysis. Pre- and post-intervention outcome changes were examined using paired t-test or Wilcoxon signed-rank tests as appropriate, and Cohen's d was calculated to estimate preliminary effectiveness. RESULTS: Of 36 eligible CRC survivors approached, 28 completed the baseline assessment, and 23 completed the post-intervention assessment. Feasibility was supported by a recruitment rate of 77.8% and a retention rate of 82.1%. Both self-report questionnaires and semi-structured interviews indicated that participants' satisfaction levels exceeded the pre-defined acceptability threshold (scores >21), confirming program acceptability. The intervention demonstrated medium effects on PA levels and health-related outcomes (Cohen's d = 0.28-0.78), supporting its preliminary effectiveness. CONCLUSIONS: This 12-week COM-B model-guided PA intervention demonstrated feasibility, acceptability, and preliminary effectiveness among CRC survivors. A full-scale randomized controlled trial is warranted to further validate the program's long-term efficacy.
PURPOSE: To validate the efficacy of a previously developed couple-based group intervention in addressing social isolation (SI) among couples coping with colorectal cancer (CRC), building on prior feasibility evidence. M...PURPOSE: To validate the efficacy of a previously developed couple-based group intervention in addressing social isolation (SI) among couples coping with colorectal cancer (CRC), building on prior feasibility evidence. METHODS: A single-site randomized controlled trial was conducted at a tertiary hospital in Wuxi, China, and enrolled 170 CRC patient-spousal caregiver dyads. Dyads were randomized to the intervention group (N = 85, standard care plus 6-week couple-based group intervention: 1 in-person plus 5 online sessions) or control group (N = 85, standard care only). Data were collected at baseline and post-intervention, with SI as the primary outcome, and health status, dyadic coping, and social support as secondary outcomes. Multilevel modeling (MLM) was used for analysis. RESULTS: 145 dyads completed post-intervention assessment (retention rate: 85.3%). MLM showed significant medium effects for perceived SI (B = 2.32, Cohen's d = 0.55, 95% CI [0.37, 0.73], P < 0.001) and structural SI (B = -1.66, Cohen's d = 0.52, 95% CI [0.34, 0.70], P < 0.001). Significant Time×Group interactions were observed for physical (PCS: B = -4.35, Cohen's d = 0.41, 95% CI [0.23, 0.59], P < 0.001) and mental (MCS: B = -4.17, Cohen's d = 0.42, 95% CI [0.24, 0.60], P < 0.001) health (small-to-medium effects). Dyadic coping had a medium effect (B = -4.58, Cohen's d = 0.52, 95% CI [0.34, 0.70], P < 0.001), social support had a small significant effect (B = -1.38, Cohen's d = 0.28, 95% CI [0.09, 0.46], P = 0.003). A significant Time×Group×Role interaction was found for perceived SI (B = -1.24, Cohen's d = 0.21, 95% CI [0.02, 0.39], P = 0.027), with caregivers showing greater improvement. CONCLUSION: The intervention improved SI, health status, dyadic coping, and social support post-intervention. Long-term efficacy remains unknown; follow-up studies (3-6 months) are needed.
BACKGROUND: Advances in diagnostics and treatments have resulted in many individuals with metastatic breast cancer living longer with the disease. A cohort has thus emerged with unique, complex and largely unmet supporti...BACKGROUND: Advances in diagnostics and treatments have resulted in many individuals with metastatic breast cancer living longer with the disease. A cohort has thus emerged with unique, complex and largely unmet supportive care needs. We performed a qualitative study to explore the views of individuals living with advanced breast cancer and healthcare professionals regarding supportive care services in this cohort. METHODS: Focus group discussions were conducted with two groups; individuals living with metastatic breast cancer (n = 10) and healthcare professionals (n = 11). QUESTIONS ADDRESSED: (1) unmet needs, (2) models and supportive care services, (3) barriers and facilitators in service delivery, and (4) future service development. Interviews were recorded, transcribed, and analysed using an inductive thematic content analysis. RESULTS: Focus group discussions revealed considerable unmet supportive care needs, varying across the trajectory of the disease. Themes included unmet supportive care needs; lack of services; unmet needs of specific groups such as males and those in the LGBTQI + community; effective types of supportive care and solutions to address unmet needs. Emphasis was placed on the need for accessible and reliable metastatic breast cancer-specific information, directed towards helping individuals live well with the diagnosis. The need for multipronged and coordinated approaches to support individuals across acute, community and palliative care services was highlighted. A shared care and patient-led model of survivorship care was preferred. Dedicated support hubs were suggested as well as improved financial and family support services. CONCLUSION: Focus groups revealed the extent and diversity of the unmet needs of individuals living with metastatic breast cancer. Findings from this research can inform the development of comprehensive supportive care services in the future.
PURPOSE: To clarify the recovery process among patients with oesophageal cancer and the patterns of association between symptoms. METHODS: A total of 887 patients undergoing oesophagectomy were recruited from four tertia...PURPOSE: To clarify the recovery process among patients with oesophageal cancer and the patterns of association between symptoms. METHODS: A total of 887 patients undergoing oesophagectomy were recruited from four tertiary hospitals. Symptom burden was assessed on postoperative day 3, day 7, day 14, and at one month. Latent class growth modelling identified symptom-burden trajectories. Regularized cross-lagged panel networks examined lagged symptom-to-symptom predictive associations across adjacent recovery stages. RESULTS: Two trajectories were identified: a high-stable symptom burden trajectory (29.5%) and a low-decreasing trajectory (70.5%). Reduced social interaction showed the highest cross-lagged out-strength in the mean network (0.840) and the highest out-expected influence across all stages (0.503, 0.529, and 1.490). In the high-stable group, cross-lagged edges increased from 19 to 28 and 36, with reduced social interaction increasingly connected to subsequent physical symptoms in the later stage. In the low-decreasing group, cross-lagged edges were 24, 19, and 24, with early and middle associations mainly among psychological symptoms. CONCLUSION: Postoperative symptoms following oesophagectomy showed distinct trajectories, and stage-specific predictive patterns. These findings support trajectory-informed risk stratification and timing-specific symptom management after oesophagectomy.
PURPOSE: To develop and evaluate the effectiveness of an mHealth-based swallowing rehabilitation program, delivered via a WeChat mini-program, for improving swallowing function, quality of life, and dysphagia-related han...PURPOSE: To develop and evaluate the effectiveness of an mHealth-based swallowing rehabilitation program, delivered via a WeChat mini-program, for improving swallowing function, quality of life, and dysphagia-related handicap in patients following partial laryngectomy. METHODS: In this single-center randomized controlled trial, 70 post-partial laryngectomy patients were allocated to a 12-week digital intervention plus routine care or routine care alone. The program integrated early functional training, intermediate feeding training, and long-term health education, providing individualized plans and real-time feedback. The primary outcome was the MD Anderson Dysphagia Inventory (MDADI), assessed at baseline, 4 weeks, and 12 weeks. Secondary outcomes included the Swallowing Quality of Life Questionnaire (SWAL-QOL) and the Dysphagia Handicap Index (DHI). RESULTS: Sixty-five patients completed the trial (intervention: n = 33; control: n = 32). At 4 and 12 weeks, the intervention group exhibited significantly greater improvements in MDADI scores compared to controls, highlighting superior outcomes at 12 weeks (87.76 ± 3.81 vs. 69.53 ± 10.88, P < 0.001). Repeated-measures ANOVA demonstrated significant time, group, and time-by-group interaction effects for SWAL-QOL and DHI scores, heavily favoring the intervention (all P < 0.001). No adverse events were reported. Adherence was high (median active usage: 51.5 days), with 92.2% continuing usage beyond the formal intervention. CONCLUSIONS: This tailored digital intervention significantly enhanced postoperative swallowing function and quality of life while reducing dysphagia-related handicap. Supported by high adherence and safety, it offers a feasible and scalable model bridging clinical and home-based recovery.
PURPOSE: Numerous studies have found evidence of the link between physical exercise and improved well-being in breast cancer patients. However, there is little research on physical exercise in a group setting that examin...PURPOSE: Numerous studies have found evidence of the link between physical exercise and improved well-being in breast cancer patients. However, there is little research on physical exercise in a group setting that examines the (re)configuration of social identities and their relationship with well-being among these patients. The study aimed to analyze the configuration of cancer patient identity and the change in its salience when a new social identification as a member of a physical exercise group is incorporated in self-concept, and how this new identity could strengthen the perception of well-being. METHOD: In this qualitative study, eighty-five female breast cancer patients participated in eleven focus groups. The narratives were qualitatively analyzed and assessed using conventional qualitative content analysis and Graneheim and Lundman's approach; systematic coding was done with ATLAS.ti software. RESULTS: The analysis revealed three main themes: 1) negative social identity: "I'm a cancer patient", 2) new positive social identity: "I'm a member of a physical exercise group", and 3) group cohesion and well-being. CONCLUSIONS: This study evidenced the role of regular physical exercise implemented in group settings as a psychosocial intervention that provides an added value beyond preventing and managing the side effects of pharmacological treatments. By acting as a structured support system, the group environment enhances patients' well-being. Therefore, healthcare systems should offer accessible, supervised, and tailored group physical exercise alongside pharmacological treatments led by multidisciplinary teams, where oncology nursing plays a pivotal role in helping patients transition beyond the 'sick identity'.
PURPOSE: To explore the eating experiences of Norwegian survivors of head and neck cancer (HNC), with a particular focus on the social aspects of food and meals. METHODS: Twelve Norwegian HNC survivors, three to five yea...PURPOSE: To explore the eating experiences of Norwegian survivors of head and neck cancer (HNC), with a particular focus on the social aspects of food and meals. METHODS: Twelve Norwegian HNC survivors, three to five years post-cancer treatment, underwent individual semi-structured interviews. We analysed the data using thematic analysis. RESULTS: The HNC survivors faced long-term side effects like taste disturbances, dry mouth, chewing, and swallowing difficulties. This made eating a demanding task, focused more on dietary intake than enjoyment. To accommodate the eating difficulties, the HNC survivors adjusted their diets to soft, easy-to-swallow foods, and prepared the food so they could manage to eat it. Many avoided social discomfort by dining more with close family or friends, and less with others. They missed the joy of savouring food and meal-centred traditions, and experienced stress around eating, concerns about others' perceptions of their eating habits, and logistical challenges, particularly when traveling. CONCLUSIONS: Physical challenges following HNC treatment disrupted participants' eating habits, social interactions, and sense of identity, several years after treatment. Many experienced ongoing emotional strains and social isolation related to eating. These findings highlight the need for survivorship care that addresses not only physical and dietary needs but also the emotional and social dimensions of eating, with potential relevance for other groups facing chronic eating challenges.
PURPOSE: This study aims to identify commonly utilised self-managed non-pharmacological interventions for managing post-treatment ULD among breast cancer survivors, evaluate their effectiveness and safety, and identify t...PURPOSE: This study aims to identify commonly utilised self-managed non-pharmacological interventions for managing post-treatment ULD among breast cancer survivors, evaluate their effectiveness and safety, and identify the research gaps for future studies. METHODS: A systematic review was conducted, and eight English databases (PubMed, Cochrane Library, Embase, CINAHL, Web of Science, Scopus, PsycINFO, and ProQuest) were searched from their inception to 30 September 2025. Google and ResearchGate were also searched to identify any additional eligible studies. Narrative synthesis was used for data analysis. Risk of Bias version 2 was used to assess the quality of the included studies. RESULTS: 5972 studies were identified by initial research, and eight studies were finally included. Commonly utilised self-managed non-pharmacological interventions for managing post-treatment ULD among breast cancer survivors were exercise-based strategies. Three studies reported a statistically significant effect on improving post-treatment ULD, and five studies reported unexpected events during interventions. Regarding the methodological quality, five studies had some concerns, and three had a high risk of bias. CONCLUSIONS: Self-managed non-pharmacological interventions for post-treatment ULD in breast cancer survivors are predominantly exercise-based. However, evidence regarding their effectiveness and safety remains inconclusive due to the limited number, heterogeneity, and methodological limitations of existing studies. Notably, evidence on non-exercise self-managed approaches is lacking. IMPLICATIONS FOR CANCER SURVIVORS: Low-intensity, structured exercise programs incorporating upper limb stretching and movement-based exercises may represent a feasible self-managed option for improving upper limb function. REGISTRATION NUMBER: INPLASY2025110066 (https://doi.org/10.37766/inplasy2025.11.0066). REVIEW PROTOCOL REGISTRATION: INPLASY2025110066 (https://doi.org/10.37766/inplasy2025.11.0066).
PURPOSE: To explore the postoperative psychosocial adaptation challenges of young and middle-aged lung cancer survivors, with a focus on their lived experiences, perceptions, and underlying cultural influences, including...PURPOSE: To explore the postoperative psychosocial adaptation challenges of young and middle-aged lung cancer survivors, with a focus on their lived experiences, perceptions, and underlying cultural influences, including social roles, etiquette, and family expectations, to guide the development of more precise and culturally sensitive psychosocial support. METHODS: A qualitative descriptive design was conducted. A total of 21 young and middle-aged lung cancer survivors were purposively recruited and interviewed using a semi-structured guide. The data were organized by NVivo 11.0 and qualitatively analyzed using thematic analysis. RESULTS: We generated an overarching theme, "psychosocial adaptation challenges: striving for a new normal". Four themes were identified: (1) unbearable threat of death, including inability to endure death, and fear of cancer recurrence; (2) symptom distress, including clearly stated symptoms and subjectively ambiguous symptoms; (3) restrictions on daily life, including activity intolerance, imposed dietary restriction, withdrawal from social activities, and adjusted work engagement; and (4) being treated differently, including feeling isolated or discriminated against, a burden of goodwill, and longing for normal. CONCLUSION: Young and middle-aged survivors following lung cancer surgery experienced severe psychosocial adaptation challenges, including challenges specific to this life stage. This study emphasizes the need for postoperative care to attend to physical recovery, psychological adjustment, and social-role reconstruction among lung cancer survivors.
Oh J, Hu Q, Fei F
… +4 more, Zhang W, Miller AH, Xiao C, Lin Y
Eur J Oncol Nurs
· 2026 May · PMID 42217521
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Full text
PURPOSE: Depressive symptoms and perceived stress are common mental health challenges among head and neck cancer (HNC) patients undergoing intensity-modulated radiation therapy (IMRT). This study examined longitudinal ch...PURPOSE: Depressive symptoms and perceived stress are common mental health challenges among head and neck cancer (HNC) patients undergoing intensity-modulated radiation therapy (IMRT). This study examined longitudinal changes in these outcomes and identified associated risk factors. METHODS: A secondary analysis was conducted using data from a prospective longitudinal study of 197 patients, with four assessment points: pre-IMRT, end of IMRT, 6 months post-IMRT, and 1-year post-IMRT. Multivariable Generalized Estimating Equation (GEE) models were used to assess temporal changes and associated risk factors, adjusting for antidepressant use. RESULTS: Depressive symptoms significantly increased from pre-IMRT to end-IMRT (B = 4.62, 95% CI [3.72, 5.53]), followed by non-significant declines at 6 months and 1 year. Perceived stress showed a non-significant increase at end-IMRT but decreased significantly at 6 months (B = -2.44, 95% CI [-3.80, -1.09]) and 1 year (B = -3.26, 95% CI [-4.88, -1.64]). Higher depressive symptoms were associated with unmarried status (B = 2.27, 95% CI [0.93, 3.61]) and percutaneous endoscopic gastrostomy (PEG) tube use (B = 1.72, 95% CI [0.57, 2.87]). Higher perceived stress was associated with younger age (B = -0.10, 95% CI [-0.18, -0.02]), female sex (B = 3.02, 95% CI [1.25, 4.80]), unmarried status (B = 4.42, 95% CI [2.62, 6.22]), and PEG tube use (B = 2.58, 95% CI [0.97, 4.19]). CONCLUSIONS: Depressive symptoms and perceived stress worsened during IMRT, with partial recovery post-treatment. Patients who are unmarried, female, younger, or require PEG support are at elevated risk. These findings highlight the need for oncology nurses to implement routine psychosocial screening across the IMRT trajectory and targeted supportive interventions for vulnerable subgroups.
PURPOSE: Chronic Lymphocytic Leukaemia (CLL) is an incurable, slow-growing blood cancer requiring lifelong surveillance and episodic treatment. While clinical management is well characterised, the experiences of patients...PURPOSE: Chronic Lymphocytic Leukaemia (CLL) is an incurable, slow-growing blood cancer requiring lifelong surveillance and episodic treatment. While clinical management is well characterised, the experiences of patients, caregivers, and practitioners remain underexplored. This review aimed to integrate these perspectives. METHODS: A qualitative evidence synthesis was conducted following ENTREQ guidelines. Systematic searches of seven databases and grey literature identified qualitative studies reporting the experiences of patients with CLL, their informal caregivers, and healthcare professionals of managing CLL. Data were analysed using thematic synthesis. RESULTS: Twenty papers reporting on fourteen studies were included. Three overarching themes emerged. Making Sense of CLL over Time captured diagnosis shock, difficulty accepting an incurable chronic illness, challenges of active surveillance, evolving information needs, and practitioners' efforts to balance clarity and reassurance. Living under the Weight of Illness and Caregiving described persistent emotional strain, illness and treatment effects, social disruption, and isolation from the patient perspective. Caregivers experienced invisible burden while clinicians reported constraints in providing sustained psychosocial support. Resilience and Adaptation in Chronicity reflected coping strategies and support systems. Clinicians highlighted relational continuity and emotional support as central to sustaining resilience. CONCLUSION: Living with CLL is a dynamic process shaped by chronic uncertainty and ongoing adaptation. Patients and caregivers seek a variety of approaches and psychosocial support to manage CLL. Unmet needs in these areas highlight opportunities to strengthen CLL care by adopting chronic-care models that integrate psychosocial care and involve caregivers.
PURPOSE: Chemotherapy-induced peripheral neuropathy is a frequent side effect of taxane-based chemotherapy, impairing function and quality of life. Exercise is recommended, but comparative effects remain unclear. This st...PURPOSE: Chemotherapy-induced peripheral neuropathy is a frequent side effect of taxane-based chemotherapy, impairing function and quality of life. Exercise is recommended, but comparative effects remain unclear. This study compared whole-body vibration resistance training and conventional aerobic and resistance training in breast cancer survivors with persistent chemotherapy-induced peripheral neuropathy. METHODS: In this randomized trial, 44 breast cancer survivors with peripheral neuropathy were randomized to whole-body vibration resistance training or conventional aerobic and resistance training. Both groups completed 12-weeks supervised intervention with assessments at baseline, 3, and 6 months. The primary outcome was chemotherapy-induced peripheral neuropathy symptom burden assessed using the Chemotherapy-Induced Peripheral Neuropathy Assessment Tool. Secondary outcomes included neuropathy-related functional disability, pain, mobility, neurological function, muscle strength, body composition, and health-related quality of life. RESULTS: Both interventions were associated with improvements in chemotherapy-induced peripheral neuropathy symptom burden over time, with no significant between-group differences for the primary outcome. Secondary outcomes differed between interventions, with conventional training associated with greater improvements in neuropathy-related functional disability, muscle strength, and mobility, whereas whole-body vibration resistance training showed a short-term increase in lean mass. Health-related quality of life improved similarly in both groups, with greater improvements in insomnia in the conventional training group. CONCLUSION: Both interventions were feasible and associated with improved outcomes. Conventional aerobic and resistance training may provide broader functional benefits, while whole-body vibration resistance training may represent a time-efficient alternative. Findings should be interpreted cautiously given the absence of a non-exercise control group and require confirmation in larger studies.
PURPOSE: To systematically review and quantify the prevalence and incidence of delirium among patients with cancer across care settings. METHOD: This systematic review and meta-analysis was reported according to PRISMA g...PURPOSE: To systematically review and quantify the prevalence and incidence of delirium among patients with cancer across care settings. METHOD: This systematic review and meta-analysis was reported according to PRISMA guidelines. Five databases (PubMed, Embase, Scopus, CINAHL, and Web of Science) were searched for studies published between January 2021 and September 2025. Eligible studies were observational cohort or cross-sectional studies reporting delirium prevalence or incidence in patients with cancer, using validated assessment tools and providing sufficient data for calculation. Two reviewers independently screened studies, extracted data, and assessed methodological quality using Joanna Briggs Institute tools. Random-effects meta-analysis was performed, with subgroup analyses and meta-regression used to explore heterogeneity. RESULTS: From 1908 identified records, 43 studies involving 242,923 participants were included. The pooled prevalence of delirium was 27.1% (9 studies; 95% CI: 14.8%-44.3%; I = 99%). The pooled incidence was 14.4% (34 studies; 95% CI: 10.9%-18.7%; I = 99%). Cancer type and delirium assessment tool were significant moderators of incidence, with neurological cancers showing the highest rates. CONCLUSIONS: This review provides updated estimates of delirium prevalence and incidence among patients with cancer, highlighting a substantial clinical burden. Findings support routine use of validated screening tools, risk-stratified surveillance, and timely nursing-led management. Future research should improve methodological consistency to better inform delirium prevention strategies in oncology care.
PURPOSE: Cancer awareness and stigma are key barriers to early help-seeking in West Asia and North Africa (WANA), with direct implications for oncology nursing education and practice. We assessed public cancer awareness...PURPOSE: Cancer awareness and stigma are key barriers to early help-seeking in West Asia and North Africa (WANA), with direct implications for oncology nursing education and practice. We assessed public cancer awareness and cancer-related stigma and examined their relationship across eight WANA countries. METHODS: A comparative cross-sectional survey was conducted between mid-December 2024 and mid-March 2025 among Arabic-speaking adults (≥18 years) from Egypt, Iraq, Jordan, Libya, Qatar, Sudan, Syria, and Yemen, recruited via online and community-based convenience/snowball approaches. Participants completed the Cancer Awareness Measure (CAM) and Cancer Stigma Scale (CASS); internal consistency was acceptable (CAM α = 0.85; CASS α = 0.87, respectively). Missing data were handled using complete-case analysis. RESULTS: The study included 1,311 adults (58.0% women; 75.9% urban). Most had never undergone cancer screening (87.1%) and had never discussed screening with a physician (85.8%). Mean (±SD) scores were 95.45 ± 19.56 (CAM) and 66.07 ± 18.09 (CASS). Awareness indicators were inversely associated with stigma; the strongest association was between perceived cancer incidence and overall stigma (r = -0.399, p < 0.001). In linear regression, higher CAM was associated with lower stigma (B = -0.181; β = -0.196, p < 0.001). In multiple regression, warning-sign awareness (β = -0.235) and perceived incidence (β = -0.345) were the strongest independent correlates of lower stigma (both p < 0.001). CONCLUSIONS: Cancer awareness was inversely associated with stigma across WANA settings. Culturally tailored, nurse-led and multidisciplinary education should strengthen symptom recognition, screening communication, and population-level cancer literacy.