ARYA Atherosclerosis[JOURNAL]
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200 papers
Prevalence of traditional atherosclerotic risk factors in newly diagnosed colorectal and breast cancer patients.
Rayati M, Mohammadifard N, Vafaei Z … +14 more , Shekarchizadeh M, Mostafavi S, Zavar R, Darakhshandeh A, Sharifi M, Ashrafi F, Khosravifarsani M, Akhavan A, Mokarian F, Najafizadeh N, Sadeghi A, Mirpourian M, Najafian J, Sarrafzadegan N
ARYA Atheroscler · 2024 · PMID 39717426 · Full text
Due to the shared risk factors between cardiovascular disease (CVD) and certain cancers such as breast cancer (BC) and colorectal cancer (CRC), our study aimed to assess the CVD risk factors among newly diagnosed patient...
Due to the shared risk factors between cardiovascular disease (CVD) and certain cancers such as breast cancer (BC) and colorectal cancer (CRC), our study aimed to assess the CVD risk factors among newly diagnosed patients with BC and CRC. The study utilized baseline data from the ongoing Cardiovascular Events in Breast and Colorectal Cancers (CIBC) cohort study conducted in Isfahan since 2019. Only patients who had recently been diagnosed with BC or CRC and had not undergone any treatment were included in the study. Trained interviewers administered questionnaires to collect information on the demographic, socioeconomic, and smoking status of the participants. Additionally, metabolic and physical factors were measured following established guidelines. A total of 542 patients were included in the study, with 394 (72.7%) diagnosed with BC, 147 (27.1%) with CRC, and one patient having both conditions. The average age of BC patients was 49.46±11.15 years, which was younger compared to CRC patients. The majority of patients (90.8%) were nonsmokers, and a significant proportion (91.2%) did not engage in sufficient physical activity. Less than half of the patients exhibited hypertension, while the prevalence of diabetes was comparatively lower. Obesity, particularly abdominal obesity, was more common among BC patients compared to CRC patients. In our population, we observed that patients with CRC had a higher mean age compared to those with BC, and they exhibited a higher prevalence of common metabolic risk factors. On the other hand, obesity was more prevalent among BC patients. In terms of the shared risk factors between CVD and BC, our population experienced menarche within the expected timeframe, and the mean age of menopause was also within the normal range.
Evaluation of short-term consequences of atrial septal defect closure in adults referred to Shahid Chamran heart center in Isfahan.
Ebrahimifar P, Dehghan H, Khosravi Farsani A
ARYA Atheroscler · 2024 · PMID 39717425 · Full text
BACKGROUND: Secundum Atrial Septal Defects (ASDs) are the most common type of atrial septal defects. Today, using different types of occluders, transcatheter closure is widely used to treat ASD and has replaced the surgi...
BACKGROUND: Secundum Atrial Septal Defects (ASDs) are the most common type of atrial septal defects. Today, using different types of occluders, transcatheter closure is widely used to treat ASD and has replaced the surgical procedure in anatomically suitable patients. This study was performed to evaluate the short-term clinical outcomes of treatment of adult patients requiring an ASD device closure referred to Shahid Chamran Cardiovascular Center in Isfahan, Iran. METHODS: All patients who underwent ASD treatment using transcatheter closure at Shahid Chamran Cardiovascular Center in 2020 and 2021 were recruited in this retrospective descriptive study. The characteristics of the treated lesion and the cardiovascular complications during treatment were recorded immediately and one month after treatment. RESULTS: A total of 70 patients (47 females and 23 males) with a mean age of 39.81±12.56 years were investigated in this study. The number of difficult anomalies was 46 (65.7%), and the most common type was the deficient aortic rim. In terms of the incidence of vascular complications, hematoma, bleeding, and pseudoaneurysm were observed in 8 patients. The most common cardiac complication was atrial fibrillation, which occurred in 12 patients. No cardiovascular complications were observed during the one-month follow-up. CONCLUSION: The results of this single-institute study showed that ASD treatment by the transcatheter procedure using an ASO device at Shahid Chamran Cardiovascular Center was performed safely and successfully with very few complications. The short-term analysis of the outcomes indicated no major complications, deaths, or device malposition.
Platelet-enriched microRNAs as novel biomarkers in atherosclerotic and cardiovascular disease patients.
Masoudikabir P, Shirazy M, Taghizadeh FS … +2 more , Gheydari ME, Hamidpour M
ARYA Atheroscler · 2024 · PMID 39717424 · Full text
BACKGROUND: Cardiovascular disease (CVD) is a global health challenge. Various studies have shown that genetic and environmental factors play roles in the development and progression of CVD. Small non-coding RNAs, namely...
BACKGROUND: Cardiovascular disease (CVD) is a global health challenge. Various studies have shown that genetic and environmental factors play roles in the development and progression of CVD. Small non-coding RNAs, namely microRNAs (miRs), regulate gene expression and have key roles in essential cellular processes such as apoptosis, cell cycle, differentiation, and proliferation. Currently, clinical studies highlight the critical role of platelets and miRs in coronary thrombosis, atherosclerosis, and CVD. METHODS: Using search engines such as PubMed and Scopus, articles studying platelet miRs and their effects on atherosclerosis and cardiovascular disease were reviewed. RESULTS: This article presents a comprehensive analysis of the association of platelet-related miRs as prognostic, diagnostic, and therapeutic biomarkers with the pathogenesis of atherosclerosis and cardiovascular disease. CONCLUSION: Taken together, data show that platelet-related miRs not only play important roles in the initial development of atherosclerosis and cardiovascular disease (CVD), but they are also considered prognostic and diagnostic biomarkers in CVD.
Correlation between transforming growth factor-β1 (TGF- β1) with premature atherosclerosis in type 1 diabetes.
Tjahjono HA, Barlianto W, Handayani D … +1 more , Kalim H
ARYA Atheroscler · 2024 · PMID 39717423 · Full text
BACKGROUND: Type 1 diabetes (T1D) carries a significant risk of atherosclerosis as the main driver for cardiovascular events. Atherosclerosis is initiated by the activation of the endothelium by various risk factors thro...
BACKGROUND: Type 1 diabetes (T1D) carries a significant risk of atherosclerosis as the main driver for cardiovascular events. Atherosclerosis is initiated by the activation of the endothelium by various risk factors through the inflammation process. The anti-inflammatory cytokine TGF-β1 may inhibit the development of atherosclerosis. METHODS: In a cross-sectional study, a total of 40 patients aged 14.5±3.16 years old with T1D and 40 healthy controls aged 14.7±0.99 years old were involved. Common carotid artery IMT (cIMT) was measured by real-time M-echocardiography mode (Affinity 50G Philips) and Flow Mediated Dilatation (FMD), using high-resolution ultrasonography and Doppler flow characteristics. The TGF-β1 level was measured by indirect ELISA at Saiful Anwar Hospital Laboratory. RESULTS: There were no differences in age, gender, Body Mass Index (BMI), duration of diabetes, renal function, or nutritional status between the T1D and healthy groups (p>0.05). A significant difference in cIMT was observed between the T1D group and the healthy group (0.567 ± 0.87 mm vs. 0.387 ± 0.57 mm, p = 0.000), FMD (7.17 ± 3.98 mm vs. 11.22 ± 5.48 mm, p = 0.000), and the level of TGF-β1 cytokine (39.83±13.51 vs. 73.67±15.34 pg/ml, p = 0.000). A significantly negative correlation between TGF-β1 and cIMT (p = 0.000; r = -0.685) and a significantly positive correlation between TGF-β1 and FMD (p = 0.000; r = +0.55) were found. CONCLUSION: Atherosclerosis is an inflammatory disease accelerated by diabetes. The inflammation process is more prominent in T1D patients. T1D patients show a decreased level of TGF-β1, increased measurement of cIMT (>0.5 mm), and a decreased measurement of FMD.
Investigation of adherence to DASH diet components and reduction of heart failure risk in adults: A case-control study.
Abbasi A, Shafie D, Heidari Moghaddam R … +2 more , Sadeghi M, Safavi SM
ARYA Atheroscler · 2024 · PMID 39717422 · Full text
BACKGROUND: Heart failure (HF), or congestive Heart failure (CHF), is a heart disorder with a number of symptoms caused by the heart's inability to pump blood. Our aim in conducting this study is to investigate the adher...
BACKGROUND: Heart failure (HF), or congestive Heart failure (CHF), is a heart disorder with a number of symptoms caused by the heart's inability to pump blood. Our aim in conducting this study is to investigate the adherence to dietary approaches to stop hypertension (DASH) diet components and the risk of HF in Iranian adult women and men. METHODS: In this hospital-based, case-control study, we included 340 participants (194 men and 146 women) aged 30-70 years who were recently (less than 6 months) diagnosed with HF. In this study, there were 169 participants in the control group and 171 participants in the case group. A semi-quantitative food frequency questionnaire (FFQ) with 148 items was used to assess food intake. Multiple logistic regression statistical tests were used to evaluate the relationship between DASH score and HF. RESULTS: After adjusting for confounding variables, the data showed that adherence to the DASH diet was associated with a reduced risk of HF. Our data show that a significant relationship was found between the consumption of fruits (OR: 0.62; 95% CI: 0.53-0.68), vegetables (OR: 0.53; 95% CI: 0.28-0.81), legumes and nuts (OR: 0.75; 95% CI: 0.65-0.68), and heart failure, but no significant relationship was found with the other components of the DASH diet and heart failure. CONCLUSION: Findings suggest that there is an inverse relationship between adherence to the DASH-style diet and the likelihood of HF, and adherence to some components of the DASH diet was also effective in reducing the risk of HF. To obtain more complete results, it is necessary to conduct cohort studies and randomized clinical trials.
Evaluating the impact of bioenergy economy-based health improvement (BEHI) as a mind-body intervention on laboratory, clinical and psychological factors in post-MI patients: A randomized controlled trial.
Farzanegan M, Hashemi Jazi MS, Derakhshan Jan A … +2 more , Sadeghi M, Roohafza H
ARYA Atheroscler · 2024 · PMID 39717421 · Full text
BACKGROUND: Patients with ischemic heart disease often exhibit various psychological factors that increase the risk of future cardiovascular events. Therefore, in addition to rehabilitation programs, there is a need for...
BACKGROUND: Patients with ischemic heart disease often exhibit various psychological factors that increase the risk of future cardiovascular events. Therefore, in addition to rehabilitation programs, there is a need for more interventional psychotherapy. Bioenergy Economy-based Health Improvement (BEHI) is a mind-body intervention that may address these issues. This study aimed to evaluate the effectiveness of the BEHI program on laboratory, clinical, and psychological factors in post-myocardial infarction (MI) patients. METHODS: In this study, 52 post-MI patients were randomly divided into two groups. One group received cardiac rehabilitation combined with the BEHI program, while the other group received only cardiac rehabilitation. Laboratory data, clinical characteristics, and psychological variables were evaluated at baseline, immediately after the intervention, and four months post-intervention (follow-up). RESULTS: Among the participants, the mean age was 59.97 ± 6.32 years, and 98.07% were male. The results showed a significant improvement in the mean scores of metabolic equivalents (METs), depression, and anxiety in participants who received the BEHI program and the rehabilitation program (p values: 0.006, 0.038, and 0.028, respectively). CONCLUSION: These findings suggest that incorporating mind-body interventions like the BEHI program into cardiac rehabilitation can enhance physical and psychological outcomes for patients recovering from MI.
Post-procedural necrotizing fasciitis following femoral coronary angiography in patient with chronic endocarditis: A case report.
Masoumi H, Shirvani E, Sattar F
ARYA Atheroscler · 2024 · PMID 39717167 · Full text
BACKGROUND: Necrotizing fasciitis is a life-threatening soft tissue infection characterized by rapid tissue necrosis, often leading to sepsis and multisystem organ failure. Necrotizing fasciitis can rarely occur as a pos...
BACKGROUND: Necrotizing fasciitis is a life-threatening soft tissue infection characterized by rapid tissue necrosis, often leading to sepsis and multisystem organ failure. Necrotizing fasciitis can rarely occur as a post-procedural complication, particularly following cardiac catheterization or angiography. This case report presents the clinical presentation and management of a 64-year-old female with a history of chronic endocarditis and valvular involvement who developed necrotizing fasciitis after femoral coronary angiography. CASE PRESENTATION: A 64-year-old female with a history of chronic endocarditis and valvular involvement underwent femoral coronary angiography as part of her cardiac evaluation. On the first postoperative day, the patient developed worsening pain, swelling, and redness in her right lower extremity, which worsened despite antibiotic therapy and pain management. The patient was diagnosed with necrotizing fasciitis. An emergent right lower extremity fasciotomy was performed to debride the necrotic tissue and release the tension caused by acute compartment syndrome. CONCLUSION: This case underscores the importance of maintaining a high index of suspicion for NF in patients with persistent soft tissue infection symptoms post-procedure. Early recognition, prompt diagnosis, and aggressive surgical intervention are crucial for the successful management of post-procedural NF following femoral coronary angiography. This report emphasizes the need for a multidisciplinary approach and vigilance in caring for patients to ensure optimal outcomes in such rare but severe complications.
Relationship between simple electrocardiographic parameter and paroxysmal atrial fibrillation.
Assadian Rad M, Shadrou H, Kazemalilou S … +2 more , Eslami Kenarsari H, Gholipour M
ARYA Atheroscler · 2024 · PMID 39717166 · Full text
BACKGROUND: Atrial fibrillation (AF) is a prevalent arrhythmia, and predicting its occurrence plays a crucial role in reducing its complications. This study aimed to investigate the relation between simple P wave paramet...
BACKGROUND: Atrial fibrillation (AF) is a prevalent arrhythmia, and predicting its occurrence plays a crucial role in reducing its complications. This study aimed to investigate the relation between simple P wave parameters and paroxysmal AF (pAF). METHODS: In this case-control study, demographic and laboratory data were gathered by a checklist. P wave parameters were measured in electrocardiography (ECG). The relationship between these parameters and AF in groups was analyzed. RESULTS: Eighty individuals were included (40 patients with pAF (57.5% female, mean age = 64.9 ± 2.04) and 40 individuals without AF (57.5% female, mean age = 60.3 ± 2.01)). The P wave peak time (PWPT) in leads D2 (p = 0.003) and V1 (p = 0.001) were longer in the case group. In addition, the prolongation of the PR interval (PR) in lead D2, P wave duration (PWD) in lead D2, and P terminal force (PTF) in V1 were associated with an increase in the occurrence of pAF. Adjusted regression analysis showed that two variables, PWPT in V1 (OR, 95% CI: 1.04 (1.01-1.07), p = 0.005) and PWD in D2 (OR, 95% CI: 1.03 (1.00-1.05), p = 0.018), were predictors for AF. CONCLUSION: Our results underscore the potential utility of simple ECG parameters, especially PWD in lead D2 and PWPT in V1, in predicting and assessing the risk of pAF. These findings provide valuable insights for clinical practice and risk stratification in patients without structural cardiac disease. Additionally, these findings may potentially contribute to the prevention of complications and injuries associated with pAF.
Predictive power of glycated hemoglobin in detecting severity of coronary artery disease in non-diabetic patients: A cross-sectional study in southern Iran.
Abbaszadeh S, Rafati S, Mamikhani D … +2 more , Emami M, Shahabi N
ARYA Atheroscler · 2024 · PMID 39717165 · Full text
BACKGROUND: The relationship between hemoglobin A1c (HbA1c) levels and coronary artery disease (CAD) severity is still a matter of debate in non-diabetic patients. This study aimed to determine the association between Hb...
BACKGROUND: The relationship between hemoglobin A1c (HbA1c) levels and coronary artery disease (CAD) severity is still a matter of debate in non-diabetic patients. This study aimed to determine the association between HbA1c and the severity of CAD in non-diabetic patients. METHODS: The present cross-sectional study was conducted in 2018-2019 on 133 non-diabetic patients with stable angina, unstable angina, or myocardial infarction (MI). They were selected through systematic random sampling. The data were collected by taking a complete medical history, calculating the SYNTAX score, and measuring HbA1c. RESULTS: A SYNTAX score of >22 was significantly correlated with age, left ventricular ejection fraction, HbA1c, and total cholesterol. The mean SYNTAX score was higher in male patients, those with HbA1c >5.6, and patients with a primary clinical presentation of MI. The association between the SYNTAX score and HbA1c was found to be statistically significant (r = 0.659; P < .001). The odds of having a SYNTAX score of >22 for those with HbA1c >5.6 was 5.48 times higher than for those with HbA1c ≤ 5.6 (odds ratio [OR], 5.48; .001). The odds of three-vessel disease in individuals with an HbA1c level greater than 5.6 were found to be 4.80 times higher than in those with HbA1c levels at or below 5.6 (OR, 4.80; 0.002). CONCLUSION: The present findings showed that HbA1c has the potential to predict the severity of CAD in non-diabetic individuals. HbA1c, even at levels within the normal range, was significantly correlated with SYNTAX scores.
Evaluation of the early effect of elective percutaneous coronary intervention on left ventricular diastolic and systolic function.
Tabatabaei SAT, Sadeghian H, Negin Taji R … +2 more , Abbasi A, Mostafavi A
ARYA Atheroscler · 2024 · PMID 39717164 · Full text
BACKGROUND: Percutaneous coronary intervention (PCI) is an effective treatment for coronary artery disease. Previous studies have demonstrated the delayed effects of PCI on left ventricular diastolic and systolic functio...
BACKGROUND: Percutaneous coronary intervention (PCI) is an effective treatment for coronary artery disease. Previous studies have demonstrated the delayed effects of PCI on left ventricular diastolic and systolic function. However, the early impact on these parameters has not been systematically examined. Moreover, no study has compared the impact of revascularization on the global longitudinal (GLS) and circumferential (GCS) strains of the left ventricle. Using echocardiographic parameters, the present study aimed to investigate the reversibility of diastolic and systolic abnormalities in patients with significant coronary artery stenosis within 1 to 2 days after PCI. Additionally, this study will compare the effects on both global and longitudinal strains. METHODS: This study included 80 consecutive patients admitted to the angiography department for elective PCI with normal left ventricular function. Echocardiography was performed before PCI and 1 to 2 days post-procedure to assess left ventricular diastolic and systolic function indices in these patients. RESULTS: The mean age of the patients was 58.0±11.9 years, with a predominantly male cohort (65%). All the patients exhibited normal left ventricular systolic function and various degrees of diastolic dysfunction. One to 2 days after revascularization, significant improvements were observed in all diastolic function indices and GLS. However, no significant improvement was found in GCS. CONCLUSION: Revascularization of a significantly stenotic coronary artery can enhance diastolic function and systolic longitudinal strain of the left ventricular myocardium as early as 1 to 2 days, with no significant impact on GCS.
A cross-sectional analysis on hypertension: Exploring the impact of lifestyle modifications and antihypertensive drug adherence in Sudan.
Ahmed A, Rikabi HA, Soomro S … +3 more , Em AE, Estabrag SH, Elham A A
ARYA Atheroscler · 2024 · PMID 39717163 · Full text
BACKGROUND: Sudan has a high prevalence of hypertension or high blood pressure, a key risk factor for cardiovascular illnesses. Therefore, this study aimed to investigate the socio-demographic characteristics, antihypert...
BACKGROUND: Sudan has a high prevalence of hypertension or high blood pressure, a key risk factor for cardiovascular illnesses. Therefore, this study aimed to investigate the socio-demographic characteristics, antihypertensive medication adherence, lifestyle changes, and the relationships between these factors and blood pressure control. METHODS: A cross-sectional study was conducted from March to August 2023 in tertiary care hospitals in Sudan. A structured questionnaire was used to gather information from 385 hypertensive individuals who participated in the study. RESULTS: The results estimated a positive correlation between the independent variables measuring medication adherence. Diet, stress management, and exercise also moderately correlated with each other and the independent variables. Systolic and diastolic blood pressure levels had a high correlation at 0.93, and most variables correlated moderately with the dependent variable of blood pressure control. The regression model (R = 0.698) using the dependent variable (blood pressure control) as the outcome strongly correlated with the independent variables, explaining almost 49% of the variance in hypertension control. It was observed that blood pressure control was significantly predicted by adherence to antihypertensive medication, proper diet, exercise, and stress reduction among the participants. CONCLUSION: The study emphasizes the significance of lifestyle changes for effective hypertension control, specifically adherence to antihypertensive medication, diet, exercise, and stress management. Hypertensive patients in Sudan experienced much better blood pressure control and a decreased risk of cardiovascular problems after changing their lifestyle.
Association between ST-segment changes in lead aVR and angiographic findings, syntax score, short-term and intermediate outcomes in patients with acute coronary syndrome: A pilot study.
Amirpour A, Masoumi H, Sadeghi M … +4 more , Zavar R, Darouei B, Mirbod SM, Amani-Beni R
ARYA Atheroscler · 2024 · PMID 39717162 · Full text
BACKGROUND: In this study, we aimed to investigate the prognostic implications of lead aVR ST-segment elevation in an initial electrocardiogram (ECG) in patients diagnosed with acute coronary syndrome (ACS). Furthermore,...
BACKGROUND: In this study, we aimed to investigate the prognostic implications of lead aVR ST-segment elevation in an initial electrocardiogram (ECG) in patients diagnosed with acute coronary syndrome (ACS). Furthermore, we evaluated the association between electrocardiographic changes in lead aVR and objective measures such as angiographic findings and Syntax score. METHODS: This retrospective cohort study, conducted as a pilot study, encompassing both a retrospective cross-sectional analysis and a longitudinal follow-up, took place at Chamran Hospital from November 2017 to October 2019. A 6-month follow-up was conducted via phone interviews to assess patient outcomes. RESULTS: During the study period, there were 76 admissions with the final diagnosis of acute coronary syndrome and lead aVR ST-segment elevation on ECG. ARB intake and the severity of right coronary artery stenosis were significantly higher in patients with STE-aVR ≥1.5 mm. The clinical pathway analysis and 6-month follow-up outcomes concerning ST-segment changes in lead aVR did not reveal statistically significant differences in the distribution of various intervention strategies and clinical events. The overall ST-change was a significant risk factor for 6-month follow-up angiography (OR: 1.10; 95% CI: 1.002 to 1.213) and was also significantly associated with any stenosis in the RCA territory (OR: 1.10; 95% CI: 1.004 to 1.21). There was no significant association between ST-change and other follow-up hospital and angiography outcomes. CONCLUSION: The findings suggest that medication history, particularly with angiotensin receptor blockers, may shape the observed ST-segment changes in lead aVR. However, further investigation is needed to better understand the clinical implications of these trends.
Unravelling the role of carotid atherosclerosis in predicting cardiovascular disease risk: A review.
Laksono S, Kusharsamita H
ARYA Atheroscler · 2024 · PMID 39717161 · Full text
Carotid atherosclerosis disease assessment can predict the patient's risk of cardiovascular disease (CVD). The purpose of this review is to provide a comprehensive review of carotid atherosclerosis disease's pathophysiol...
Carotid atherosclerosis disease assessment can predict the patient's risk of cardiovascular disease (CVD). The purpose of this review is to provide a comprehensive review of carotid atherosclerosis disease's pathophysiology, diagnostic evaluation, imaging applications, and treatment strategies. Carotid atherosclerosis is diagnosed using a variety of techniques, including transcranial Doppler imaging (TCD), computed tomography angiography (CTA), magnetic resonance angiography (MRA), and cerebral digital subtraction angiography (DSA), with duplex ultrasound (DUS) as the primary screening. Measurements of carotid intima-media thickness (CIMT) have drawn attention recently as a marker of early-stage carotid atherosclerosis or CVD risk prediction. The classification of cardiovascular risk may be enhanced by the expanding fields of stress testing and carotid plaque screening.
Development and efficacy of mobile application to improve medication adherence for persons with cardiac disease.
Ghafouri R, Karbaschi R, Mashhadi Hosein A … +1 more , Sharifian S
ARYA Atheroscler · 2024 · PMID 39697854 · Full text
BACKGROUND: Patients with cardiovascular disease need to adhere to their treatment and care recommendations to prevent the progression of their condition and improve their quality of life. In this regard, this study was...
BACKGROUND: Patients with cardiovascular disease need to adhere to their treatment and care recommendations to prevent the progression of their condition and improve their quality of life. In this regard, this study was conducted to develop a mobile application and test its effectiveness in improving medication adherence among persons with cardiac disease. METHODS: The study was conducted in two stages. The first stage involved the preparation of the "Mobile Application for Persons with Cardiac Disease" using the cascade model. In the second stage, 121 patients who were hospitalized in the cardiac intensive care unit of Ayatollah Taleghani Medical Education Center of Tehran from March to August 2023 were enrolled. The participants were randomly assigned to either the control group (63 people) or the intervention group (58 people). The study collected data using a medication adherence questionnaire on the 7th, 14th, and 21st day after discharge and compared the results with the control group. The data were analyzed using SPSS 20. RESULTS: The average age of the control group was 56.75 ± 11.38 years, and the average age of the intervention group was 57.03 ± 11.55 years. The comparison of the average medication adherence with independent t-tests showed a significant difference between the intervention and control groups on the 7th, 14th, and 21st day after discharge (P<0.01). The results of the repeated measures test in each group also showed that the difference between the groups increased over time (P<0.001). CONCLUSION: The results of the study showed that the mobile application is effective in improving medication adherence among heart patients.
The impact of home care on individuals with chronic heart failure: A comprehensive review.
Kalhor F, Shahzeydi A, Taghadosi M
ARYA Atheroscler · 2024 · PMID 39697853 · Full text
BACKGROUND: Heart failure is a widespread condition linked to elevated mortality rates, readmission incidents, and healthcare expenditures. Home care has emerged as a promising strategy for managing patients with heart f...
BACKGROUND: Heart failure is a widespread condition linked to elevated mortality rates, readmission incidents, and healthcare expenditures. Home care has emerged as a promising strategy for managing patients with heart failure. This study seeks to comprehensively review the impact of home care on individuals diagnosed with heart failure. METHODS: A comprehensive review was conducted by searching for relevant articles in Persian and English using keywords such as 'Nursing,' 'Home care,' 'Home care services,' Health Care Costs,' 'Heart diseases,' and 'Heart failure' across various databases including SID, Magiran, Ovid, Scopus, Web of Science, CINAHL, ProQuest, Embase and Medline. The search was limited to articles published between 2000 and 2023, focusing on those suitable for the study's purpose. RESULTS: A total of 1,260 articles were initially identified. After eliminating duplicate and irrelevant articles, evaluating the availability of full texts, and applying entry and exit criteria, as well as utilizing the CONSORT, STROBE checklist, and JBI Checklist for qualitative assessment of the studies, a total of 13 English articles were deemed suitable for inclusion in the final review. These studies utilized various study designs to investigate the effects of home care on patients with heart failure. CONCLUSION: The findings of this study suggest that home care has a positive impact on the quality of life, knowledge, and self-care of patients with heart failure. Additionally, it has been shown to reduce healthcare costs, readmission rates, and mortality. Therefore, it is recommended to prioritize home care for patients with chronic heart failure following discharge.
Evaluation of the prevalence and predictors of right ventricular diastolic dysfunction in patients undergoing coronary artery bypass surgery.
Abedi J, Ghafari ME, Kheirkhah J … +2 more , Moladoust H, Aghajankhah MR
ARYA Atheroscler · 2024 · PMID 39697852 · Full text
BACKGROUND: With the increase in the number of coronary artery bypass grafting (CABG) surgeries, the concern about complications after it has also increased. RV diastolic dysfunction (RVDD) is one of the post-CABG compli...
BACKGROUND: With the increase in the number of coronary artery bypass grafting (CABG) surgeries, the concern about complications after it has also increased. RV diastolic dysfunction (RVDD) is one of the post-CABG complications, and in this study, we intend to investigate its frequency and predictors. METHODS: In this cross-sectional study, eighty CABG candidate adult patients were included. A history of previous heart surgery or arrhythmia were the main exclusion criteria. After recording demographic and clinical information, echocardiography of the right ventricle (RV) was performed the day before the surgery and seven days later. The functional parameters were obtained according to the Guidelines for the Echocardiographic Assessment of the Right Heart in Adults. RESULTS: Eighty patients with an average age of 60.25 ± 8.93 years participated in the study. Most patients were male (72.5%). Thirteen patients had RVDD before CABG (30.8% grade I and 69.2% grade II). All these 13 patients had RVDD grade II after surgery (P=0.046). Among 67 patients with normal RV function before CABG, RV function was normal in only 20 patients (29.9%) after CABG. The incidence of grade I and grade II post-CABG RVDD (post-coronary artery bypass grafting right ventricle diastolic dysfunction) was 11.9% and 58.2%, respectively (P<0.001). Univariate logistic regression analysis showed that there was no association between pre-CABG variables, neither demographic nor echocardiographic, and the occurrence of RVDD after CABG. CONCLUSION: CABG surgery is associated with a high incidence of RVDD, which cannot be predicted before surgery. The short-term and long-term consequences of this complication are still unknown.
Short-term and long-term clinical outcomes of percutaneous coronary intervention on saphenous vein grafts.
Nikfarjam S, Salari A, Mirbolouk F … +6 more , Pourrajabi A, Ghasemi M, Ghadiri Asli SA, Masoum Zadeh Kiaee SB, Fakhr-Mousavi SA, Ghafari ME
ARYA Atheroscler · 2024 · PMID 39697851 · Full text
BACKGROUND: Ischemic heart disease (IHD) is the leading cause of 16% of deaths globally. Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are the main treatment options. Saphenous vein...
BACKGROUND: Ischemic heart disease (IHD) is the leading cause of 16% of deaths globally. Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are the main treatment options. Saphenous vein grafts (SVGs) remain the most frequently used conduits for CABG. In addition, PCI in cases previously undergoing CABG is related to worse long-term outcomes. This study aimed to evaluate PCI's short-term and long-term clinical outcomes on SVGs. METHODS: Sixty-three patients who underwent PCI on SVGs from 2017 to 2019 were enrolled. Short-term and long-term cardiac outcomes of patients in the 6-month follow-up, including major adverse cardiac events (MACE) and all causes of death, were collected. The collected data were also analyzed through statistical methods. RESULTS: The mean age of the subjects was 63.26 ± 8.74 years. Out of 63 patients, five patients (7.94%) died. Two of them died because of cardiac death a day after PCI, and three other cases passed away during the 6 months after angioplasty. Four and three cases had non-fatal myocardial infarction and stroke 6 months after PCI, respectively. CONCLUSION: In conclusion, in patients with coronary artery disease, PCI and CABG are complementary therapies. Revascularization on saphenous vein grafts seems to be a safe and practical technique in patients.
Delayed coronary air embolism post re-do mitral valve replacement: A case report.
Nezafati P, Yadav S
ARYA Atheroscler · 2024 · PMID 39697850 · Full text
BACKGROUND: Coronary air embolism (CAE) is a complication that can lead to catastrophic outcomes, including myocardial infarction, stroke, and death. It is reported to occur during cardiac catheterization, within a few h...
BACKGROUND: Coronary air embolism (CAE) is a complication that can lead to catastrophic outcomes, including myocardial infarction, stroke, and death. It is reported to occur during cardiac catheterization, within a few hours after cardiac surgery, or as a result of chest trauma. This is a case report of delayed coronary air embolism following cardiac surgery. CASE PRESENTATION: A 58-year-old female presented with New York Heart Association (NYHA) Class II symptoms resulting from severe, highly eccentric anterior mitral regurgitation from a bio-prosthetic valve. She had preserved ejection function and a total calcium score of zero. This patient underwent a re-do mechanical mitral valve replacement. Two days post-surgery, she was brought to the catheterization laboratory with signs and symptoms suggestive of an inferior myocardial infarction (MI) and complete heart block (CHB). Her symptoms and ST changes resolved immediately after the introduction of angiographic contrast. Angiography revealed no occlusion in the right coronary artery (RCA).
Temporal trend of short-term mortality in acute myocardial between 2000-2017: A multi-centric Iranian registry.
Paknahad MH, Teimouri-Jervekani Z, Roohafza H … +5 more , Sarrafzadegan N, Nouri F, Nasirian S, Baharlouei Yancheshmeh F, Sadeghi M
ARYA Atheroscler · 2024 · PMID 39697849 · Full text
BACKGROUND: The study explores the enduring challenges of cardiovascular disease mortality, emphasizing myocardial infarction rates as a proxy for cardiovascular disease in Iran. It analyzes the 28-day mortality trends a...
BACKGROUND: The study explores the enduring challenges of cardiovascular disease mortality, emphasizing myocardial infarction rates as a proxy for cardiovascular disease in Iran. It analyzes the 28-day mortality trends after Acute Myocardial Infarction (AMI) from 2000 to 2017. METHODS: This retrospective cohort study is based on data from a multi-centric hospital-based registry in Isfahan. Univariate and multivariate frailty Cox regression analyses were performed to identify Hazard Ratios (HRs) for the 28-day mortality rate of AMI based on age, gender, and living region. RESULTS: The study enrolled 121,284 patients with an average age of 62.00±12.82 years. Older age than 65 years was found to be associated with an increased risk of AMI (HR: 3.2, 95% CI: 2.7-3.8 from 2000 to 2002 and HR: 4.6, 95% CI: 3.7-5.7 for 2015-2017). There was also an association between living in the urban region and a decreased risk of AMI from 2000 to 2005 (HR: 0.64, 95% CI: 0.46-0.90), from 2000 to 2002 (HR: 0.55, 95% CI: 0.43-0.71 for 2003-2005). Results showed that the trend of change in 28-day mortality declined more significantly from 2006 to 2017 compared to 2000-2002. Younger age (61.76±12.69 vs 71.12±11.73), female gender (HR:0.77, 95%CI: 0.67,0.89), and living in urban regions (HR: 0.69, 95%CI: (0.52,0.94) were the protective factors for the 28-days mortality rate of AMI. CONCLUSION: It can be concluded that 28-day mortality had a descending trend from 2006 to 2017. Older age, male gender, and living in a rural region were the risk factors that affected the 28-day mortality rate of AMI.
Coronary artery calcification score as the determinant of coronary artery disease in chronic kidney disease patients: A preliminary study.
Moradi M, Talebi A, Shavakhi S … +2 more , Tarrahi MJ, Meraji Far F
ARYA Atheroscler · 2024 · PMID 39697848 · Full text
BACKGROUND: Coronary computed tomography angiography (CCTA) is a noninvasive cardiovascular imaging procedure that visualizes coronary artery calcifications (CAC), a marker of subclinical atherosclerosis. Due to differen...
BACKGROUND: Coronary computed tomography angiography (CCTA) is a noninvasive cardiovascular imaging procedure that visualizes coronary artery calcifications (CAC), a marker of subclinical atherosclerosis. Due to different calcification patterns in patients with chronic kidney disease (CKD) compared to the general population, this study aims to present diagnostic cut-off values for CAC to detect early coronary artery disease (CAD) in CKD patients. METHODS: This cross-sectional study included 807 patients: 407 with CKD and 400 controls with normal kidney function who underwent CCTA during 2019-2021. CAC score measurements were performed for all left main coronary arteries to investigate CAD. The Coronary Artery Disease Reporting and Data System (CAD-RADS) was used as the gold standard to determine the value of CAC, and diagnostic values were measured. RESULTS: The number of female patients was 443 (54.9%), and 364 (45.1%) were male. The mean age in the case group was 63.95 ± 10.26 years, and in the control group, it was 53.80 ± 11.84 years. At the cut-off point of 85, the CAC score had a sensitivity and specificity of 84.7% and 83%, respectively, among patients with CKD to detect CAD (Area Under the Curve (AUC): 0.919, 95% CI: 0.89-0.94; P-value < 0.001). Considering a cut-point of 85 for CAC, the frequency of healthy subjects with CAD-RADS less than two was significantly higher than the cases (P-value = 0.012), while the two groups were similar regarding CAD-RADS 3-5 (P-value = 0.83). CONCLUSION: According to this study, the CAC score is a valuable means to detect CAD among CKD subjects. There is no significant difference in CAC between patients with substantial CAD-RADS in CKD and non-CKD patients. The cut-point of 85 for the CAC score was found valuable to diagnose CAD with over 80% sensitivity and specificity.
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