Complementary Therapies In Medicine[JOURNAL]
Sun
200 papers
The health effects of diaphragmatic breathing: A systematic review.
Kwon CY, Won J, Lee B
Complement Ther Med · 2026 Mar · PMID 41482169 · Publisher ↗
BACKGROUND: Diaphragmatic breathing (DB) is widely used clinically, but a comprehensive synthesis of randomized controlled trial (RCT) evidence on its health effects is lacking. This systematic review evaluated the healt...
BACKGROUND: Diaphragmatic breathing (DB) is widely used clinically, but a comprehensive synthesis of randomized controlled trial (RCT) evidence on its health effects is lacking. This systematic review evaluated the health effects of DB interventions in adults based on RCT evidence. METHODS: Six electronic databases were searched through January 2025 for RCTs comparing DB to control conditions in adults. Two reviewers independently selected studies, extracted data, and assessed risk of bias (Cochrane RoB 2). A narrative synthesis was performed due to substantial heterogeneity across studies. RESULTS: We included 48 RCTs. DB protocols were highly heterogeneous, with parameters varying widely in breathing frequency (2-10 breaths/min), session duration (3-45 min), and total duration (single session to 12 weeks). Methodological quality was a significant concern (only 2.12 % of outcomes low risk of bias). Consistent benefits were found for gastroesophageal reflux disease (GERD) (including reduced medication use), anxiety, post-COVID-19 syndrome, and gestational diabetes). In healthy adults, DB showed acute cardiovascular benefits. However, evidence was inconsistent for chronic obstructive pulmonary disease, and DB was less effective than standard care after cardiac surgery. Safety was underreported (18.75 % of studies), but no serious adverse events were noted. CONCLUSIONS: DB is a promising complementary therapy for specific conditions, including GERD, but the evidence base is constrained by methodologically weak and heterogeneous primary studies. Future research requires rigorous, standardized trial designs to establish its clinical value. Despite these limitations, DB is a low-cost, accessible, and apparently safe intervention for select conditions.
Beyond the 'Crack': Reframing thrust manipulation through neurophysiology, perception, and context.
Romero Rosado Á, Martínez Pozas O, Carnero SF … +3 more , Cuenca Zaldívar JN, Sánchez Romero EA, Sillevis R
Complement Ther Med · 2026 Mar · PMID 41461256 · Publisher ↗
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Recent trends and disparities in movement behaviors and internalizing symptoms among U.S. youth with chronic pain.
Le H, Zhang Z, Gao Y
Complement Ther Med · 2026 Mar · PMID 41443409 · Publisher ↗
BACKGROUND: Temporal dynamics and sociodemographic disparities (e.g., age, sex, ethnicity, and household income) in movement behaviors-such as adherence to physical activity (PA) and screen time (ST) guidelines-and inter...
BACKGROUND: Temporal dynamics and sociodemographic disparities (e.g., age, sex, ethnicity, and household income) in movement behaviors-such as adherence to physical activity (PA) and screen time (ST) guidelines-and internalized symptoms, including anxiety and depression, remain largely understudied. Therefore, we aimed to investigate recent trends and sociodemographic disparities in movement behaviors and internalizing problems among youth with chronic pain. METHODS: Cross-sectional analyses were conducted using data from the National Survey of Children's Health (NSCH) which includes U.S. youth aged 6-17 years with chronic pain. In this study, survey data covering the period between 2018 and 2022, was used to investigate temporal trends in movement behaviors and Internalizing symptoms, followed by sub-group analyses (i.e., age group, sex, ethnicity, household poverty level, and the education level of primary caregivers). RESULTS: Data from 11,362 participants with chronic pain (mean age = 11.55 years [SD, 3.41]; 4866 [41.86 %] boys) were analyzed. Regarding movement behaviors, mean ST duration increased from 2.8 h in 2018-2.9 h in 2022 (P for trend = 0.02). Meanwhile, the estimated prevalence of meeting PA guideline decreased from 18.3 % to 11.5 % (P for trend = 0.001). Regarding internalizing problems, significant increases were observed in the prevalence estimates of anxiety (27.8 % to 35.0 %, P for trend = 0.001) and depression (15.9 % to 21.6 %, P for trend = 0.004). Relative to their peers, both adolescent and girl participants exhibited a lower estimated prevalence of adherence to movement behaviors guidelines, as well as a higher prevalence of internalizing problems. By contrast, White participants reported higher estimated prevalence rates for both adherence to movement behaviors guidelines and internalizing problems. DISCUSSION: This study investigated temporal trends in movement behavior and internalized problems among youth with chronic pain in the United States and identified significant differences across age, sex, and ethnic subgroups. Findings underscore the importance of continuous monitoring of movement behavior and internalized problems and underscore the need for relevant stakeholders (e.g., policymakers) to account for the influence of sociodemographic factors when aiming to promote a healthy lifestyle in such a vulnerable population.
Comparative effects of static, classical, and sham dry needling on muscle properties and autonomic nervous system activity in cervical myofascial pain syndrome.
Olaniszyn G, Kużdżał A, Taradaj J … +1 more , Trybulski R
Complement Ther Med · 2026 Mar · PMID 41386496 · Publisher ↗
BACKGROUND: Dry needling is frequently used for managing myofascial pain, yet the influence of needle manipulation technique on physiological responses remains uncertain. OBJECTIVE: To compare the short-term effects of c...
BACKGROUND: Dry needling is frequently used for managing myofascial pain, yet the influence of needle manipulation technique on physiological responses remains uncertain. OBJECTIVE: To compare the short-term effects of classical dynamic (pistoning) dry needling (CDN), static dry needling (SDN), and sham needling (shamN) on mechanical and microcirculatory properties of the upper trapezius muscle. METHODS: In this randomized, single-blind, sham-controlled trial, 45 participants with upper-trapezius myofascial trigger points were allocated to CDN (n = 15), SDN (n = 15), or shamN (n = 15). CDN involved multiple fast in-out needle insertions to elicit local twitch responses, SDN consisted of a single needle insertion retained for 60 s without manipulation, and shamN simulated insertion without skin penetration. Outcomes included pressure pain threshold (PPT, N/m²), muscle stiffness (N/m), tone (Hz), elasticity (D), and perfusion (PU), recorded at baseline, immediately, 60 min, 24 h, and 7 days post-intervention. Data were analyzed with mixed (Group × Time) ANCOVA models using baseline as covariate. RESULTS: A significant main effect of time was observed for PPT (p = 0.039, η²ₚ = 0.071) and a significant Time × Group interaction for elasticity (p < 0.001, η²ₚ = 0.974) and perfusion (p < 0.001, η²ₚ = 0.483). Post hoc comparisons showed higher PPT and perfusion and lower stiffness and tone in CDN compared with SDN and shamN across most time points (p < 0.05). No significant differences were found between SDN and shamN. CONCLUSIONS: CDN induced greater short-term improvements in mechanical and perfusion outcomes of the upper trapezius than static or sham procedures, suggesting that needle manipulation intensity modulates physiological responses. Long-term studies are warranted to confirm sustained clinical relevance. TRIAL REGISTRATION: ISRCTN16484644.
Yoga-Nidra as a complementary therapy for reducing psychological distress and enhancing quality of life in cancer patients: A randomized controlled trial.
Baruah M, Poovamma CU, Narayanan P … +4 more , Harish P, Keshav R, Babu N, Pandey M
Complement Ther Med · 2026 Mar · PMID 41349728 · Publisher ↗
PURPOSE: Intensive cancer treatments, including surgery, chemotherapy, and radiation, are physically and emotionally taxing, often causing psychological distress and reduced quality of life. Complementary therapies are i...
PURPOSE: Intensive cancer treatments, including surgery, chemotherapy, and radiation, are physically and emotionally taxing, often causing psychological distress and reduced quality of life. Complementary therapies are increasingly explored to mitigate these effects. Yoga-Nidra, a non-invasive, low-cost, low-effort relaxation technique, may benefit patients with limited mobility during treatment. This study examines its impact on psychological distress and quality of life in cancer patients. METHODS: This randomized controlled trial included 40 cancer patients (ages 25-55) undergoing chemotherapy, radiation, hormone, or immunotherapy. After informed consent, participants were randomly assigned to the Yoga-Nidra (n = 20) or control group (n = 20). The intervention involved 25-minute sessions, twice daily, five days a week for one month. Psychological distress and quality of life, including functioning, symptoms, and global health were assessed pre- and post-intervention using the NCCN Distress Thermometer and EORTC QLQ-C30. RESULTS: Yoga-Nidra demonstrated significant improvements over the control group across multiple quality-of-life domains, including psychological distress (p = .001), global health (p = .010), emotional-functioning (p = .028), social-functioning (p < .001), and symptoms of fatigue (p = .003), pain (p = .002), dyspnea (p < .001), and diarrhea (p = .015). Post-hoc analyses confirmed greater benefits for distress (p = .005), emotional-functioning (p = .004), and dyspnea (p = .008). CONCLUSION: Yoga-Nidra reduces psychological distress and improves quality of life in cancer patients. As an accessible complementary therapy, it supports emotional well-being and symptom management during intensive treatments. Further research is needed to assess its effects on less responsive domains, related symptoms, long-term efficacy, and applicability across diverse patient populations.
The progress and application of hot spring hydrotherapy in medical fields: A narrative review.
Lv Y, Li D, Liu R … +1 more , He Y
Complement Ther Med · 2026 Mar · PMID 41319719 · Publisher ↗
Natural hot spring water has been known for its healing and wellness properties for thousands of years. Hot spring hydrotherapy a form of natural therapy, the medical effects of it mainly involves a comprehensive effect...
Natural hot spring water has been known for its healing and wellness properties for thousands of years. Hot spring hydrotherapy a form of natural therapy, the medical effects of it mainly involves a comprehensive effect of multiple aspects such as physics, chemistry, biology and psychology. This paper starts from the current stage of the application of hot spring hydrotherapy in the field of medicine, analyses the recent research on hot spring hydrotherapy in the medical field in order to form a comprehensive understanding of hot spring hydrotherapy. The recent literature and systematic reviews were surveyed and summarized, hot spring hydrotherapy is very effective in solving skin diseases, rheumatism, digestive system diseases, respiratory system diseases, nervous system diseases and cardiovascular diseases. In addition, the selection of hot spring and treatments should be considered for different conditions as hot spring hydrotherapy is not suitable for all diseases. Hot spring hydrotherapy can be considered a safe and generally well-accepted intervention in health care to alleviate symptoms and improve quality of life, and hopes that it can provide a certain reference basis for the research of the relevant content in the future.
Duration of music listening in music-induced analgesia: A pilot randomized controlled trial.
van der Valk Bouman ES, Becker AS, Smienk M … +5 more , Horstink MMB, de Vos CC, Jeekel H, De Zeeuw CI, Klimek M
Complement Ther Med · 2026 Mar · PMID 41314516 · Publisher ↗
BACKGROUND: Music is a non-pharmacological treatment that is effective for pain relief. However, the extent to which duration of listening to music influences music-induced analgesia (MIA) is unclear. METHODS: In this pi...
BACKGROUND: Music is a non-pharmacological treatment that is effective for pain relief. However, the extent to which duration of listening to music influences music-induced analgesia (MIA) is unclear. METHODS: In this pilot randomized controlled trial, healthy volunteers (n = 80) were subjected in a parallel design to music for 0, 1, 5 or 20 min. Pain was induced by increasing electric stimuli using the Biopac program Stimusol. MIA was assessed at baseline, at the end of the experimental period with music (intervention), and after a five-minute washout period without music. Data were analyzed using linear mixed models to account for measurement sequences. RESULTS: For the intervention measurement, pain endurance did not differ between groups. However, pain threshold was higher in the 20-minute group (β = 2.5, p < 0.001), but not in the 1-minute and 5-minute groups, compared to the control group. On average, perceived pain intensity and unpleasantness were somewhat lower in all music groups compared to the control group, but none of these differences were significantly different. Emotional valence was higher in the music groups compared to the control group, which was significant only for the 1-minute group (β = 0.6, p = 0.027). Albeit not consistently, heart rate variability indicated more sympathetic activity in all music groups. For the washout measurement, no clear trends were visible. CONCLUSION: Translating these findings to clinical care, it seems advisable for patients to listen to music for a sufficient amount of time (≥20 min) to achieve effective MIA. Further research is needed to validate these results and determine the optimal "dosage" for MIA.
Switching minds: A theoretical model of cognitive speed gaps, emotional reactivity, and behavioural self-regulation.
Tay A
Complement Ther Med · 2025 Dec · PMID 41284514 · Publisher ↗
OBJECTIVES: Although emotional dysregulation and behavioural impulsivity are common traits across clinical and non-clinical populations; current cognitive models frequently overlook the timing dynamics underlying such ph...
OBJECTIVES: Although emotional dysregulation and behavioural impulsivity are common traits across clinical and non-clinical populations; current cognitive models frequently overlook the timing dynamics underlying such phenomena. This paper introduces the Tay Reactive-Reflective Processing Model (T-RRPM) to address this gap. METHODS: T-RRPM is a theoretical framework based on the mind-body interaction. It is a novel mechanism of emotional regulation failure: a cognitive speed mismatch between the fast-reacting subconscious mind and the slower, deliberative conscious mind. The model conceptualises the subconscious as a developmentally younger, emotionally reactive system akin to a "5 -10 year-old child", and the conscious mind viewed as a rational Chief Executive Officer (CEO). When emotionally-salient stimuli are experienced, the subconscious responds rapidly with patterned emotional impulses, often before the conscious mind can reflect and intervene. RESULTS: This regulatory lag results in emotional flooding, impulsive behaviours, and internal conflict-even in individuals with insight or self-awareness. By foregrounding cognitive timing and subconscious age, T-RRPM contributes a mechanistic explanation of how emotional regulation often fails in real time. CONCLUSIONS: The model offers testable hypotheses and practical applications across the fields of psychotherapy, education, trauma recovery, and behavioural coaching. T-RRPM also supports the development of timing-based self-regulation strategies, reframing reactive behaviour not as moral failure but as a remediable misalignment between inner systems. This paper contributes a novel conceptual mechanism for emotional regulation failure based on cognitive latency. This theoretical model has broad relevance across psychotherapy, trauma-informed practice, behavioural coaching, and integrative health modalities.
Dance therapy in fibromyalgia: A narrative review.
Salazar CAS, Velasco SS
Complement Ther Med · 2026 Mar · PMID 41271180 · Publisher ↗
IMPORTANCE: Fibromyalgia (FM) is a significant public health issue, particularly prevalent among women aged 20-55, with prevalence rates ranging from 2 % to 8 %. It is characterized by widespread musculoskeletal pain and...
IMPORTANCE: Fibromyalgia (FM) is a significant public health issue, particularly prevalent among women aged 20-55, with prevalence rates ranging from 2 % to 8 %. It is characterized by widespread musculoskeletal pain and is associated with various comorbidities, making it a complex and costly condition to treat. Non-pharmacological interventions, such as dance therapy, emerge as promising alternatives to address both the physical symptoms and psychosocial aspects of FM. OBSERVATIONS: Literature review indicates that dance therapy offers multiple benefits, including improvements in mobility, quality of life, and emotional well-being for FM patients. This form of therapy has been shown to help reduce pain and enhance coping through self-expression and social connection. However, limitations in the research persist, such as a lack of standardization in intervention methods and a scarcity of studies evaluating the safety of these practices. CONCLUSIONS AND RELEVANCE: Dance-based interventions may represent an effective therapeutic tool for managing fibromyalgia, promoting both physical health and emotional well-being. As the evidence base grows, it is crucial to continue investigating different modalities of dance therapy to determine their specific benefits and standardize interventions. This could not only improve the quality of life for FM patients but also contribute to a more holistic and effective approach in treating this complex condition.
Bridging tradition and innovation: Acupuncture for depression through clinical efficacy and neurobiological insights.
Xu N, Xu S, Wang L
Complement Ther Med · 2026 Mar · PMID 41265714 · Publisher ↗
BACKGROUND: To elucidate the research progress on acupuncture therapy as a complementary and alternative medicine treatment for depression by reviewing existing literature. METHODS: We conducted a comprehensive search ac...
BACKGROUND: To elucidate the research progress on acupuncture therapy as a complementary and alternative medicine treatment for depression by reviewing existing literature. METHODS: We conducted a comprehensive search across PubMed, Embase, Web of Science, and China National Knowledge Infrastructure databases for relevant literature from inception to October 7, 2024. Additionally, we manually searched medical literature related to Chinese Medicine and acupuncture for pertinent theories and theoretical frameworks. RESULTS: Manual acupuncture (MA) and electroacupuncture (EA) are the most commonly studied forms of acupuncture, demonstrating efficacy in modulating depression both as standalone therapies and as adjunct therapies for antidepressants in the short to medium-term. Other modalities such as auricular acupuncture, laser acupuncture, and warm acupuncture have also shown benefits in managing depression. The therapeutic mechanisms of acupuncture are multifaceted, including modulation of neural networks, regulation of neurotransmitters, neurotrophic factors, and neuropeptides, inhibition of neuroinflammation and Hypothalamic-Pituitary-Adrenal (HPA) axis hyperactivity, restoration of neuroplasticity, modulation of specific gene expression, and regulation of intestinal flora. Recent studies emphasize the need for collaboration between acupuncture, engineering, and modern technology for the future development of acupuncture techniques. CONCLUSIONS: Acupuncture has shown efficacy in treating depression through multi-targeted modulation within the body. Moving forward, acupuncture is poised to enhance its practice by cooperating with engineering and digital technologies to offer patients more comprehensive and personalized treatment plans.
Comparative efficacy of different mind-body exercise modalities in low back pain: Systematic review and network meta‑analysis.
Tian Q, Li D, Xiong H … +3 more , Zhu T, Li X, Huang W
Complement Ther Med · 2026 Mar · PMID 41265713 · Publisher ↗
OBJECTIVE: To assess and compare the effectiveness of commonly used mind-body exercise modalities for the treatment of low back pain (LBP), and to provide evidence to inform clinical decision-making and policy developmen...
OBJECTIVE: To assess and compare the effectiveness of commonly used mind-body exercise modalities for the treatment of low back pain (LBP), and to provide evidence to inform clinical decision-making and policy development. DESIGN: Systematic review and network meta-analysis. LITERATURE SEARCHS: PubMed, Embase, Cochrane Library, and Web of Science were searched from inception to May 2025. STUDY SELECTION CRITERIA: Randomised controlled trials comparing mind-body exercise interventions with each other or with control groups in patients with clinically diagnosed low back pain. Studies involving postsurgical patients were excluded. DATA SYNTHESIS: Two reviewers independently screened studies, extracted data, and assessed the risk of bias using the Cochrane Risk of Bias 2 tool (RoB2). Certainty of evidence was rated using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) framework. A frequentist network meta-analysis was conducted using standardised mean differences (SMD) for pain outcomes. RESULTS: Thirty-two randomized controlled trials (RCTs) involving 2480 participants were included. Pilates was associated with the greatest reduction in pain compared with usual care (SMD -1.56; 95 % CI -2.10 to -1.02; moderate certainty evidence), followed by taiji and qigong. The pain reduction associated with Pilates exceeded the prespecified minimal clinically important difference. Yoga did not significantly differ from control in follow-up. Surface Under the Cumulative Ranking curve (SUCRA) supported the superiority of Pilates. CONCLUSIONS: Mind-body exercises-particularly Pilates-are effective non-pharmacological options for managing low back pain. Pilates may offer the most meaningful short-term pain relief. These findings support the integration of structured mind-body programmes into standard LBP care pathways and highlight the need for further direct comparisons between modalities.
Impact of a yoga intervention over 6, 12, and 24 months in sedentary climacteric women with metabolic syndrome.
Cota E Souza LA, Guerra-Sá R, Lima AA
Complement Ther Med · 2026 Mar · PMID 41260565 · Publisher ↗
Metabolic syndrome (MetS) and climacteric symptoms often coexist in middle-aged women, increasing cardiovascular risk and reducing quality of life. Yoga shows promise for improving both metabolic and psychological outcom...
Metabolic syndrome (MetS) and climacteric symptoms often coexist in middle-aged women, increasing cardiovascular risk and reducing quality of life. Yoga shows promise for improving both metabolic and psychological outcomes, but its long-term effects in this population remain understudied. Therefore, this study evaluated the effects of a structured Shivam Yoga training program over 6, 12, and 24 months on metabolic syndrome (MetS) and menopausal symptoms in climacteric women. A total of 102 women with MetS were assigned to a yoga intervention or control group, with assessments at baseline, 6, 12, and 24 months. Primary outcomes included climacteric symptoms, anthropometric data, and biochemical and clinical parameters. The Yoga group showed a significant reduction in MetS frequency at 6 months (-20.8 %; p = 0.028) and 24 months (-46.0 %; p = 0.007) compared to controls. Fasting glucose decreased significantly at all time points (up to -21.54 mg/dL; p = 0.001), and HDL cholesterol increased at 24 months (+20 mg/dL; p = 0.001). At 24 months, waist circumference, systolic blood pressure, and diastolic blood pressure also declined significantly. Climacteric symptoms improved consistently in the Yoga group, with lower Kupperman Index scores and reductions in nervousness at every follow-up (p < 0.05). Additional improvements included insomnia, depressive symptoms, and palpitations at 6 months, with sustained reductions in palpitations (-32.2 %; p = 0.043) and arthralgia/myalgia (-46.0 %; p = 0.007) at 24 months. These findings suggest that Shivam Yoga may offer sustained benefits for both metabolic health and menopausal symptom relief in women with MetS.
Effects of seated Baduanjin training modalities on body composition, muscle strength, and gait parameters in older adults: A cluster-randomised controlled trial.
Chen CF, Chiu SC, Chiang CK … +1 more , Lu YW
Complement Ther Med · 2025 Dec · PMID 41213338 · Publisher ↗
BACKGROUND AND OBJECTIVE: The relationship between seated exercise frequency and physiological changes in older adults has received insufficient research attention. We examined how Baduanjin session frequency, Baduanjin...
BACKGROUND AND OBJECTIVE: The relationship between seated exercise frequency and physiological changes in older adults has received insufficient research attention. We examined how Baduanjin session frequency, Baduanjin instructional format, and low-intensity resistance training affect the body composition, muscle strength, and gait parameters of older adults. METHODS: A prospective, cluster-randomised, controlled, two-arm trial was conducted at day care centres for older adults in Taiwan over 12 weeks between May and September 2024. The experimental group received a multicomponent seated Baduanjin intervention which included online and in-person sessions and additional resistance training, whereas the control group completed only the online Baduanjin sessions. Body composition was assessed using bioelectrical impedance analysis. Muscle strength of the upper and lower extremities was measured using handheld dynamometers. Gait parameters were evaluated using GaitUp wearable motion sensors. RESULTS: Linear mixed-effects analysis revealed significant between-group differences in grip strength, gait speed, cadence, and load ratio after 12 weeks (p < 0.05). The experimental group maintained their functional abilities, whereas the control group experienced marked declines. No significant changes were observed in skeletal muscle index, body fat percentage, or isometric knee extensor force over the intervention period. Additionally, the foot-flat ratio significantly decreased in the experimental group (p = 0.004) but increased in the control group (p = 0.011); the between-group difference was significant (B = 5.28, 95 % confidence interval [2.14, 8.41], p = 0.001). CONCLUSION: The multicomponent seated Baduanjin intervention was more effective than the once-weekly Baduanjin sessions in improving physical outcomes. Thus, Baduanjin is a safe, feasible, and beneficial. intervention for older adults. This study was registered on ClinicalTrials.gov (Registration No. NCT06550661) on 6 August 2024.
What are the effects of connective tissue massage vs. myofascial release on fibromyalgia pain? Systematic review with meta-analysis.
Ide FC, D'Oliveira A, Vieira EP … +3 more , Martins TB, Andrade A, do Nascimento IB
Complement Ther Med · 2026 Mar · PMID 41207644 · Publisher ↗
OBJECTIVE: to verify the impact of the use of connective tissue massage (CTM) technique versus myofascial release (MFR) performed manually by the therapist and foam roller self-myofascial release (FRSMR) performed by the...
OBJECTIVE: to verify the impact of the use of connective tissue massage (CTM) technique versus myofascial release (MFR) performed manually by the therapist and foam roller self-myofascial release (FRSMR) performed by the patient on fibromyalgia pain-related outcomes. METHOD: this is a systematic review and meta-analysis, performed in the PubMed, Web of Science, Scopus, SciELO, LILACS, and Embase databases. The PRISMA 2020 guidelines were followed, and the risk of bias was assessed using the National Institutes of Health tool, with agreement measured by Cohen's Kappa. RESULTS: 10 studies were included in the qualitative synthesis and meta-analysis. Dysfunctions of the muscle fascia contribute to the pathogenesis of fibromyalgia and can directly influence pain and central sensitization. In the meta-analysis, under the random-effects model, MFR significantly reduced pain (SMD = -1.16, p = 0.0003), whereas CTM did not reach significance (p = 0.29). By contrast, the fixed-effect model underestimated the results due to heterogeneity. CONCLUSION: MFR has is more effective prognosis in pain reduction compared to CTM. However, the efficacy of MFR depends on the demographic and adaptive factors of the individuals and, especially, on the methodological definition of the intensity and time for which the MFR technique should be applied. In populations of different age groups, FRSMR techniques are recommended to be adapted. The personalized and specific approach of MFR suggests that it could be a promising strategy in the management of fibromyalgia, with the possibility of more robust and sustainable outcomes.
Can transcutaneous electrical acupoint stimulation prevent postoperative nausea and vomiting?
Liu Y, Chen Z, Zhang Z … +5 more , Hu Q, Wang J, Cao R, Liu W, Wang L
Complement Ther Med · 2025 Dec · PMID 41197783 · Publisher ↗
Postoperative nausea and vomiting (PONV) is a common perioperative complication that can increase the incidence of complications such as aspiration, bleeding, incision dehiscence water-electrolyte disorders; prolong hosp...
Postoperative nausea and vomiting (PONV) is a common perioperative complication that can increase the incidence of complications such as aspiration, bleeding, incision dehiscence water-electrolyte disorders; prolong hospital stays; and increase medical costs. Transcutaneous electrical acupoint stimulation (TEAS) is important for preventing perioperative PONV, and TEAS may reduce the incidence of PONV by activating the brain-gut axis and regulating autonomic nerve function, anti-inflammatory activity and other mechanisms; however, it is necessary to further promote standardized clinical application through mechanistic research, parameter optimization and high-quality clinical research. This article discusses the risk factors for PONV, the possible mechanism of TEAS in the prevention of PONV and the clinical application of TEAS to provide some reference for the clinical application of TEAS in preventing PONV.
Effectiveness of aromatherapy on physiological and psychological symptoms during pregnancy: a systematic review and meta-analysis.
Mascarenhas VHA, Caroci-Becker A, Nick JM … +4 more , Sahin S, Drigo RTDC, Riesco ML, Lima MOP
Complement Ther Med · 2025 Dec · PMID 41192533 · Publisher ↗
AIM: To evaluate the effectiveness of aromatherapy in reducing physiological and psychological symptoms during pregnancy. METHODS: This review followed the JBI methodological guidelines for Systematic Reviews of Effectiv...
AIM: To evaluate the effectiveness of aromatherapy in reducing physiological and psychological symptoms during pregnancy. METHODS: This review followed the JBI methodological guidelines for Systematic Reviews of Effectiveness and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Guided by the PICO framework: population (P) comprised pregnant women; intervention (I) was aromatherapy; comparison (C) included conventional treatment, other complementary therapies, or placebo; outcomes (O) involved physiological and psychological symptoms. Experimental and quasi-experimental studies involving pregnant women who received aromatherapy to manage these symptoms were included. Nine databases were searched in January 2022 and August 2024, including Medline, CINAHL, SCOPUS, and Web of Science, yielding 1063 registers. RESULTS: Twenty-one studies were included (16 randomised controlled trials and five quasi-experimental), conducted in Iran, Indonesia, Japan, and Taiwan. Meta-analysis revealed that aromatherapy significantly reduced nausea and vomiting (standardised mean difference [SMD] = -0.92; 95 % confidence interval [CI]: -1.09, -0.74) and maternal anxiety (SMD = -0.67; 95 % CI: -0.95, -0.40). Improvements in sleep quality were also noted (mean difference = -1.55; 95 % CI: -2.09, -1.01). CONCLUSION: Aromatherapy appears to be an effective and safe option for alleviating certain gestational symptoms. Citrus essential oils such as peppermint, bitter orange, lemon, and mint have been shown to reduce nausea and vomiting. Citrus aurantium, Rosa damascene, mint, and orange blossom have demonstrated efficacy in reducing maternal anxiety. Citrus aurantium, orange blossom, and lavender may also improve sleep quality. However, further high-quality studies with larger sample sizes are warranted. REGISTRATION: This systematic review was registered in PROSPERO.
Complementary therapies for chronic knee pain: A placebo-controlled RCT of Reiki and mindfulness.
Hanley AW, Nakamura Y, Edwards RR … +7 more , Lingard A, Childs K, Faulkner J, Schnitt R, Vaca-St Claire S, Bridge E, Garland EL
Complement Ther Med · 2025 Dec · PMID 41183719 · Publisher ↗
CONTEXT: Knee osteoarthritis (KOA) is a prevalent chronic pain condition that significantly impairs quality of life and is often treated with interventions that carry risks or provide limited relief. Reiki, a non-invasiv...
CONTEXT: Knee osteoarthritis (KOA) is a prevalent chronic pain condition that significantly impairs quality of life and is often treated with interventions that carry risks or provide limited relief. Reiki, a non-invasive complementary therapy, has shown early promise for pain management but lacks rigorous evaluation among American adults with KOA. OBJECTIVES: This study evaluated the specific efficacy of Reiki and mindfulness for adults with chronic KOA pain compared to sham and waitlist control conditions. METHODS: In this placebo-controlled randomized trial, 164 adults with physician-confirmed KOA were assigned to one of four groups: Reiki, sham Reiki (i.e., Feiki), mindfulness meditation, or a waitlist control. Active treatments were delivered in four weekly 30-minute sessions. RESULTS: KOA symptom severity, assessed using the WOMAC at baseline, 1-month, and 2-month follow-ups, significantly improved in both the Reiki (p = .02) and mindfulness (p < .001) groups compared to waitlist controls. Mindfulness significantly outperformed Feiki (p = .004). Reiki demonstrated effects comparable to mindfulness (p = .22). Clinically meaningful reductions in symptoms (>30 %) were reported by 55 % of participants in the Reiki and mindfulness groups, compared to 20 % in the Feiki group and 13 % in the waitlist group. High retention (96 %) and successful blinding support the feasibility and internal validity of this approach. CONCLUSIONS: These findings indicate that both Reiki and mindfulness may offer effective, well-tolerated, and time-efficient alternatives for managing KOA-related pain, with meaningful symptom improvement after just two hours of intervention. Larger trials are warranted to confirm efficacy and explore long-term outcomes and underlying mechanisms.
Meta-analysis of yoga-based mind-body interventions in the management of inflammatory bowel disease.
Pan L, Chen X, Wu Y … +2 more , Zhou Z, Xu D
Complement Ther Med · 2025 Dec · PMID 41183718 · Publisher ↗
BACKGROUND: Inflammatory bowel disease (IBD) affects millions worldwide and imposes both physical and psychological burdens. While current treatments have limitations, yoga-based mind-body interventions (YMBIs) show prom...
BACKGROUND: Inflammatory bowel disease (IBD) affects millions worldwide and imposes both physical and psychological burdens. While current treatments have limitations, yoga-based mind-body interventions (YMBIs) show promise in improving symptoms and quality of life through physiological and stress-regulating pathways. OBJECTIVE: This Meta-analysis seeks to comprehensively and objectively assess the efficacy of yoga-based mind-body interventions on psychological, physical, and inflammatory outcomes in patients with IBD. METHODS: A comprehensive search was conducted in both international and Chinese databases including PubMed, EMBASE, Cochrane Library, Web of Science, Medline, China National Knowledge Infrastructure (CNKI), WanFang, and China Biomedical Literature Service System. Randomized controlled trials (RCTs) comparing YMBIs with standard care or placebo in IBD patients were pooled from inception to February 17, 2025. Data were analyzed using RevMan 5.4 and Stata 16.0, with standardized mean differences (SMDs) and 95 % confidence intervals (CIs) as effect measures. RESULTS: Seven RCTs comprising 502 participants were included. The meta-analysis revealed that YMBIs significantly reduced anxiety (SMD = -0.56, 95 % CI [-0.77 to -0.36], P < 0.0001), depression (SMD = -3.45, 95 % CI [-5.52 to -1.37], P < 0.0001), and perceived stress (SMD = -0.70, 95 % CI [-1.00 to -0.39], P < 0.0001), while improving quality of life (SMD = 0.47, 95 % CI [0.17-0.77], P = 0.002). Effects on sleep quality (SMD = -1.98, 95 % CI [-3.98-0.02], P = 0.05) and disease activity (SMD = -0.26, 95 % CI [-0.52-0.01], P = 0.05) were modest, with borderline statistical significance. CONCLUSION: YMBIs alleviates psychological distress and enhance well-being in IBD patients, though their impact on disease progression remains uncertain. However, their effects on sleep quality and disease activity require further validation through high-quality clinical studies. SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/PROSPERO/view/CRD420250653339.
Efficacy and safety of traditional Chinese exercises in cardiac rehabilitation of patients after percutaneous coronary intervention: A systematic review and meta-analysis.
Jiale W, Longcheng L, Haisheng Y … +5 more , Qiushuang Y, Xiaodi J, Anqi W, Ying Z, Lihong M
Complement Ther Med · 2025 Dec · PMID 41183717 · Publisher ↗
PURPOSE: Percutaneous coronary intervention (PCI) is one of the most important therapies in patients with coronary heart disease (CHD). However, there are still many problems, such as in-stent restenosis, recurrent angin...
PURPOSE: Percutaneous coronary intervention (PCI) is one of the most important therapies in patients with coronary heart disease (CHD). However, there are still many problems, such as in-stent restenosis, recurrent angina pectoris, postoperative anxiety and depression. Traditional Chinese exercise (TCE) therapies belong to the aerobic exercise of low and medium intensity which movements are soft and the combination of movement and static, which may have a certain efficacy on cardiac rehabilitation of patients after PCI. Therefore, this study systematically reviewed the reported clinical studies of TCE on cardiac rehabilitation in patients after PCI to explore its efficacy and safety. METHODS: We searched for RCTs on patients after PCI in 8 Chinese and English databases from their inception to Aug 2024. We included patients after PCI, with the intervention group receiving TCE (alone and/or combined with conventional treatment and/or exercise) and the control group receiving only conventional treatment and/or exercise. We screened the literatures and extracted the data. And we used the Cochrane "Risk of bias" tool and GRADE tool to assess the quality of studies and evidence. We used RevMan 5.4 to analyze the results. RESULTS: Fifty-three studies involving 4700 patients after PCI were included. TCE therapy includes Baduanjin, Tai Chi, Wuqinxi and Yi Jinjing. Conventional treatment(CT) included basic drugs, routine nursing, nutritional guidance and psychological intervention. Conventional exercise (CE) included walking, jogging or other aerobic exercise, resistance training, balance and flexibility training. Methodological quality was of high risk of bias in blinding of participants and personnel as well as unclear of bias in blinding of outcome assessment and allocation concealment. Grade evaluation results suggested low or very low quality of evidence. For the incidence of major adverse cardiovascular events rate, left ventricular ejection fraction, NT-ProBNP, six-minute walk distance, left ventricular end diastolic diameter, left ventricular end-systolic diameter, VO max, anaerobic threshold, metabolite equivalents, seattle angina questionnaire and short form 36 health survey questionnaire, treatment group is superior to control group (P＜0.05). For VO peak, there was no significant difference between the two groups (P＞0.05). CONCLUSIONS: The results of this study showed that TCE may have efficacy in reducing the incidence of MACE, improving the cardiac function, exercise endurance and quality of life of patients after PCI. And the efficacy of the TCE therapy combined with CT and/or CE may be better than that of the CT and/or CE and the safety may be better.
The effects of exercise interventions on sleep quality in patients with emotion-related insomnia (ERI)：A systematic review and network meta-analysis.
Ouyang B, Gao J, Zhou X … +2 more , Gao L, He H
Complement Ther Med · 2025 Dec · PMID 41177371 · Publisher ↗
UNLABELLED: This meta-analysis consequently endeavors to methodically evaluate the impact of exercise interventions on sleep quality measures in populations affected by ERI.The study intends to develop an evidence-based...
UNLABELLED: This meta-analysis consequently endeavors to methodically evaluate the impact of exercise interventions on sleep quality measures in populations affected by ERI.The study intends to develop an evidence-based prioritization framework for exercise types, offering support for the customization of exercise prescriptions in clinical practice. METHODS: This study was evaluated by literature search in five databases, and analyses were subsequently conducted using Review Manager 5.3 and STATA 18.0. Furthermore, a meta-regression analysis was employed to examine the potential moderating effects of exercise intervention characteristics. RESULTS: Pairwise meta-analysis demonstrated that exercise significantly improved subjective sleep quality [SMD = -0.83, (95 % CI = -1.17, -0.49),P < 0.001].Network meta-analysis revealed that several exercise types are potentially effective interventions for enhancing subjective sleep quality: aerobic exercise (AE) (SMD = -0.66, 95 % CI: -1.19, -0.14, p < 0.05), combined exercise (CE) (SMD = -1.17, 95 % CI: -2.07, -0.26, p < 0.05), and Body and mind exercise (BM) (SMD = -0.71, 95 % CI: -1.35, -0.07, p < 0.05). Among these, CE [SMD = -1.17, 95 % CI: -2.07, -0.26, p < 0.05; SUCRA = 77.9 %] was identified as the most likely modality for improving subjective sleep quality.Meta-regression analysis indicated that exercise cycles (β = -0.470, p < 0.05) and exercise frequency (β = -0.940, p < 0.05) may be significant moderators influencing the effect of exercise on sleep onset latency (SOL). CONCLUSION: Exercise was effective in improving subjective sleep quality.CE, AE, and BM may represent preferential modalities for enhancing subjective sleep quality, with CE potentially constituting the most effective intervention.exercise frequency and exercise cycles are identified as potential significant moderators influencing the improvement of SOL.
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