Braz Oral Res [JOURNAL]
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200 papers
Association between depression, anxiety, and stress and oral health-related quality of life in adolescents.
Borstmann EDS, Brondani B, Knorst JK … +5 more , Siqueira BDP, Lima LS, Ramadan YH, Emmanuelli B, Ardenghi TM
Braz Oral Res · 2025 · PMID 41092149 · Full text
This cross-sectional study aimed to evaluate the association between the degree of depression, anxiety, and stress and oral health-related quality of life (OHRQoL) of adolescents aged 11 to 19 years from Santa Maria, Bra...
This cross-sectional study aimed to evaluate the association between the degree of depression, anxiety, and stress and oral health-related quality of life (OHRQoL) of adolescents aged 11 to 19 years from Santa Maria, Brazil. The Child Perception Questionnaire (CPQ 11-14) was used to evaluate OHRQoL. The degree of anxiety, depression, and stress was assessed using the Depression, Anxiety and Stress Scale - Short Form (DASS-21). Additionally, sociodemographic, clinical, and psychosocial variables were considered. Adjusted Poisson regression models were applied to examine the associations between predictive variables and overall CPQ11-14 scores. Results are reported as rate ratio (RR) and 95% confidence intervals (95% CI). A total of 164 adolescents were evaluated. The mean DASS-21 scores for depression, anxiety, and stress were 6.9 (standard deviation [SD] 9.0), 8.7 (SD 8.9), and 11.9 (SD 9.7), respectively. The mean CPQ 11-14 score was 12.2 (SD 10.3). Adolescents with high levels of depression (RR = 1.03; 95%CI: 1.02-1.05) and stress (RR = 1.02; 95%CI: 1.01-1.04) presented higher CPQ 11-14 scores, indicating a significant impact of those symptoms on OHRQoL. In conclusion, adolescents with high depression and stress scores experienced poorer OHRQoL, highlighting the need for integrated mental health and oral health interventions to improve their overall well-being.
Additional root canal enlargement increases immediate postoperative pain: a randomized controlled trial.
Harter AL, Gomes FA, Xavier SR … +3 more , Malhão EC, Souza EM, Pappen FG
Braz Oral Res · 2025 · PMID 41092148 · Full text
This prospective, double-blind, randomized clinical trial aimed to evaluate the effect of an additional instrument following the single-file instrumentation approach on postoperative pain. Fifty-six mandibular molars wit...
This prospective, double-blind, randomized clinical trial aimed to evaluate the effect of an additional instrument following the single-file instrumentation approach on postoperative pain. Fifty-six mandibular molars with asymptomatic apical periodontitis were randomly assigned to two groups: G1 - instrumentation using a single reciprocating file; G2 - additional enlargement. The frequency and intensity of postoperative pain were assessed at 24 h, 48 h, and 7 days after endodontic treatment using the numerical pain assessment scale (NPAS) (Mann-Whitney U test). Analgesic intake was also recorded and analyzed using chi-square or Fisher's exact tests. The incidence of root canal filling extrusion was also evaluated (chi-square). Statistical significance was set at p < 0.05. At 24 h, the incidence of postoperative pain was higher when additional enlargement was performed (p = 0.019). The incidence of pain was similar between groups after 48 h (p = 0.121) and 7 days (p = 1.000). The intensity of pain was also higher at 24 h in Group 2 (p = 0.019), while it was similar between groups after 48 h (p = 0.177) and 7 days (p = 1.000). The frequency of analgesic intake was higher in Group 2 after 24 h (p = 0.019). The incidence of root canal filling material extrusion was similar in both groups (p = 0.181). In conclusion, additional enlargement following single-file root canal preparation resulted in a higher incidence and intensity of postoperative pain immediately after treatment (24 h), with no significant impact at 48 h and 7 days.
Factors associated with adherence to post-exposure prophylaxis among dental professionals in Brazil.
Silva GCBD, Viani ACMM, Marinho AMCL … +2 more , Pordeus IA, Abreu MHNG
Braz Oral Res · 2025 · PMID 41092147 · Full text
This study analyzed the influence of sociodemographic, occupational, and accident-related factors on adherence to post-exposure prophylaxis (PEP) among dental professionals. A cross-sectional study was conducted using se...
This study analyzed the influence of sociodemographic, occupational, and accident-related factors on adherence to post-exposure prophylaxis (PEP) among dental professionals. A cross-sectional study was conducted using secondary data from the Brazilian Notifiable Diseases Information System, covering incidents of biological material exposure from 2018 to 2023 across all federal units. PEP adherence was the outcome analyzed, and related factors included sociodemographic, occupational, and accident characteristics. Descriptive, bivariate, and multivariate logistic regression analyses were performed (α = 5%). A total of 15,650 notifications involving dental professionals were analyzed, representing 3.91% of all cases of occupational exposure, with a PEP adherence rate of 91.0%. The exposed professionals had a mean age of 32.5 years (SD = 10.4), were predominantly women (76.6%), of White race/ethnicity (65.4%), and had higher education (79.7%). The mean work experience was 3.6 years (SD = 6.8). In the adjusted model, adherence was associated with lower educational attainment (OR = 0.71; 95%CI: 0.58-0.88), younger age (OR = 0.99; 95%CI: 0.98-0.99), and longer work experience (OR = 1.02; 95%CI: 1.01-1.03). Percutaneous exposure (OR = 1.39; 95%CI: 1.16-1.67), contact with blood (OR = 1.47; 95%CI: 1.18-1.82), and dental procedure-related accidents (OR = 1.35; 95%CI: 1.07-1.70) increased the likelihood of adherence. Hepatitis B vaccination (OR = 1.96; 95%CI: 1.62-2.36) was associated with increased adherence to PEP. Adherence to PEP was influenced by multiple factors, highlighting the need for effective strategies to improve adherence and occupational safety among these professionals.
Prediction of marginal adaptation failure in restorations of non-carious cervical lesions, based on machine learning.
Bronholo TPM, Freitas PFJ, Ferraz AX … +6 more , Cruz KRD, Favoreto MW, Baratto-Filho F, Reis A, Loguercio AD, Araujo CM
Braz Oral Res · 2025 · PMID 41092146 · Full text
Marginal adaptation failure in noncarious cervical restorations (NCCRS) significantly compromises restoration longevity and adversely impacts patient outcomes. early identification of high-risk restorations is therefore...
Marginal adaptation failure in noncarious cervical restorations (NCCRS) significantly compromises restoration longevity and adversely impacts patient outcomes. early identification of high-risk restorations is therefore of clinical importance. This study aimed to develop and evaluate a supervised machine learning (ML) model capable of predicting the risk of marginal adaptation failure in NCCRS within 18 months following treatment. A total of 262 restorations were analyzed, incorporating multiple clinical variables, including adhesive system used, cavity geometry, degree of dentin sclerosis, incisogingival height, tooth characteristics, and patient age. Seven supervised ml algorithms were trained and assessed: decision tree, support vector machine (SVM), gradient boosting, k-nearest neighbors (KNN), logistic regression, multilayer perceptron, and random forest. model performance was evaluated using fivefold cross-validation and standard metrics, including the area under the receiver operating characteristic curve (AUC), accuracy, recall, precision, and F1 score. Key predictive features identified were incisogingival height, patient age, and type of adhesive system. the auc values ranged from 0.72 (95% confidence interval [95%CI]: 0.57-0.88) to 0.52 (95%CI: 0.51-0.83), and recall values ranged from 0.77 (95%CI: 0.66-0.89) to 0.53 (95%CI: 0.40-0.66). Among the tested algorithms, SVM, gradient boosting, and KNN demonstrated superior predictive performance. these findings suggest that ml models can serve as effective tools for predicting restoration failure and may assist clinicians in optimizing post-treatment monitoring and follow-up strategies for patients with NCCRS.
Exposure of the Brazilian population to risk factors for oral cancer.
Morais HGF, Costa LMD, Ribeiro RR … +4 more , Galvão MHR, Roncalli AG, Miguel MCDC, Freitas RA
Braz Oral Res · 2025 · PMID 41092145 · Full text
The aim of this study was to investigate the profile of the Brazilian population exposed to risk factors for oral cancer, as well as the profile of patients in the high-risk group for this disease in Brazil. This study r...
The aim of this study was to investigate the profile of the Brazilian population exposed to risk factors for oral cancer, as well as the profile of patients in the high-risk group for this disease in Brazil. This study relied on a cross-sectional design, utilizing secondary data from the 2020 National Health Survey (PNS). The database used contained information on 90,846 individuals aged 18 and older. The dependent variable was "High-risk group for oral cancer development" and the independent variables were grouped into biological characteristics, educational level, access to health services, and self-care practices. In the multivariate analysis, odds ratios of outcomes were assessed using a logistic regression model. Individuals of white ethnicity, with low levels of education, residing in rural areas, not registered in the Family Health Strategy program, who have rarely or never seen a dentist, self-assessing their general health as poor, and lacking regular physical exercise were more likely to be in the high-risk group for the development of oral cancer. The data from the 2020 National Health Survey (PNS) demonstrate that a large portion of the Brazilian population is exposed to risk factors for oral cancer. This highlights the disparities in access to medical and dental health services, as well as in the educational and preventive interventions by healthcare professionals regarding risk factors for oral cancer.
Modified Child Dental Anxiety Scale-Faces (MCDASf): validity and reliability of the Brazilian version.
Goettems ML, Almeida FV, Demarco GT … +3 more , Azevedo MS, Costa VPPD, Barbosa TS
Braz Oral Res · 2025 · PMID 41092144 · Full text
Specific measures for assessing dental anxiety and fear are crucial in pediatric dentistry for their management. This cross-sectional study aimed to test the validity and reliability of the Brazilian Portuguese version o...
Specific measures for assessing dental anxiety and fear are crucial in pediatric dentistry for their management. This cross-sectional study aimed to test the validity and reliability of the Brazilian Portuguese version of the Modified Child Dental Anxiety Scale - Faces (MCDASf). A total of 189 children enrolled in public schools in Pelotas, Southern Brazil, and their parents were included. The children completed an interview that included the MCDASf, Children's Fear Survey Schedule-Dental Subscale (CFSS-DS), Dental Anxiety Question (DAQ), and self-reported oral health-related outcomes. The parents provided sociodemographic data and information on dental visits and pain. Descriptive statistics, comparison and correlation tests, and psychometric analyses were conducted. The MCDASf scores were positively correlated with the CFSS-DS scores (rho = 0.60; p < 0.001). Children reporting dental anxiety (DAQ) had higher MCDASf scores. Exploratory factor analysis (EFA) was conducted on MCDASf items. The factor model was supported by Bartlett's test of sphericity (p < 0.001) and the Kaiser-Meyer-Olkin (KMO) measure (0.782). The loadings indicated that the two factors explained 18.9% and 13.9% of the variance. Factor 1 included items 1-3, 5, 7, and 8, whereas Factor 2 included items 4 and 6. The MCDASf showed satisfactory internal consistency: Cronbach's α = 0.73 and McDonald's ω = 0.82 for the total scale, with α and ω > 0.66 for both factors. Coefficients ≥ 0.70 are considered acceptable. This study provided psychometric evidence supporting the Brazilian MCDASf (B-MCDASf) as a reliable self-report tool for assessing dental anxiety in children in both clinical and research settings.
Comparison of oral conditions between the Macuxi and Yanomami indigenous ethnicities.
Roman-Torres CVG, Boaventura RM, Kussaba ST … +3 more , Cruz DSD, Sendyk WR, Pallos D
Braz Oral Res · 2025 · PMID 41092143 · Full text
In the state of Roraima, Brazil, indigenous populations have distinct cultural habits and ethnic characteristics compared to those of the nonindigenous population. Changes in the oral health of indigenous people are crit...
In the state of Roraima, Brazil, indigenous populations have distinct cultural habits and ethnic characteristics compared to those of the nonindigenous population. Changes in the oral health of indigenous people are critical areas of investigation for generating oral health indicators, which significantly influence the overall health of this population, given their fundamental role in the development of public health policies. Our objective was to compare the oral conditions of indigenous people of the Yanomamis (YANs) and Macuxis (MACs) ethnicities in the state of Roraima. A total of 148 indigenous people were evaluated: 83 (53.50%) YANs and 65 (46.50%) MACs. All indigenous participants were assessed at the Indigenous Health House (CASAI), in the municipality of Boa Vista/RR, and data regarding oral condition, DMFT index, periodontal indices, basic erosive wear examination (BEWE) index, and eating habits were obtained. Significant differences were found in the DMFT index, which was higher for MAC individuals than for YAN individuals (P<0.05). Periodontal evaluation revealed a significantly larger probing depth in YAN individuals aged over 35 years. Plaque index was higher for YAN individuals, with a significant difference noted in all compared groups. As for the BEWE index, no statistically significant difference was observed between YAN and MAC individuals. With respect to eating habits, YAN individuals consumed significantly more native foods, whereas MAC individuals consumed predominantly processed foods. Periodontal indices are affected by poor oral hygiene, and oral hygiene instruction and guidance are necessary and could help reduce the incidence of dental caries and periodontal disease.
After all, what is the proper use of Kappa statistics in oral health surveys? What don't manuals tell us?
Assaf AV, Silva RPD, Mialhe FL … +1 more , Pereira AC
Braz Oral Res · 2025 · PMID 41092142 · Full text
The aim of this study was to elucidate, unclear points of the "Oral Health Survey: basic methods", of the World Health Organization (WHO), relative to reproducibility (encompassed reliability and agreement) issues during...
The aim of this study was to elucidate, unclear points of the "Oral Health Survey: basic methods", of the World Health Organization (WHO), relative to reproducibility (encompassed reliability and agreement) issues during examiners' calibration. Thus, Kappa statistics and percent agreement were calculated for a sample of 10 12-year-old schoolchildren examined by 1 gold standard examiner and 5 dentists from Nova Friburgo, RJ, Brazil, in 2018, under the WHO and SB Brasil 2010 Project settings. Weighted Kappa was used to measure reliability between 2 examiners, and Fleiss' Kappa for 5 examiners. Tooth-to-tooth reliability was also assessed. The results showed that, although the choice of different settings invariably produced different reliability and agreement values, this approach was feasible, coherent and even desirable depending on the purpose of an epidemiological survey conducted. Kappa values were slightly lower in the SB Brasil 2010 Project setting. The results for tooth-to-tooth reliability, in turn, allowed identification of teeth (in this sample, teeth 17, 23, 27, 34, 37, 44, 45, and 47) for which additional examiner calibrations would be necessary. It is concluded that providing additional information for inclusion in the WHO manual, such as the possibility of varying the setting, adopting the tooth-by-tooth unit, and selecting the correct type of Kappa statistic depending on the number of examiners, within a multilevel calibration proposal, may result in more reliable results during the calibration stage.
Referrals for frenotomy/frenectomy between 2017-2022 to public dental services in Ribeirão Preto, Brazil.
Vilela LD, Lima RB, Oliveira AA … +5 more , Miranda Filho AEF, Mestriner SF, Silva LAB, Vanderlei KMHO, Silva RABD
Braz Oral Res · 2025 · PMID 41092141 · Full text
In this study, referrals for lingual frenotomy/frenectomy (F/F) were evaluated in children younger than 7 years the public dental services of Ribeirão Preto, São Paulo, Brazil, from 2017 to 2022. In this longitudinal obs...
In this study, referrals for lingual frenotomy/frenectomy (F/F) were evaluated in children younger than 7 years the public dental services of Ribeirão Preto, São Paulo, Brazil, from 2017 to 2022. In this longitudinal observational retrospective study, the Hygiaweb System (Power BI) platform to access electronic medical records, and the following variables were collected: incidence of F/F, reports of symptoms associated with ankyloglossia, duration of exclusive breastfeeding (EBF), professional categories requesting the referral, and multiprofessional evaluation. Descriptive analyses, associations between variables, comparisons between groups and incidence ratios were performed. The significance level was set at 5%. During the study period, 242 procedures were performed, the majority of them in children younger than 1 year, with an increasing trend towards F/F (p = 0.028, S = 11). The estimated incidence was 40.6 F/F per 10,000 inhabitants. Among all children who underwent F/F, the majority were breastfed for up to 1 month (101, 41.7%), followed by 4 to 5 months (56, 23.1%). There was no significant association between exclusive breastfeeding for 6 months and lingual frenectomy before 6 months of age (p = 0.444). Confirmation of the need for lingual frenectomy was associated with multidisciplinary assessment at referral (p < 0.001; Cramér's V = 0.268). It can be concluded that organization of the care process and the breastfeeding support movement may have had a positive influence on the management of cases and the upward trend towards F/F procedures. Multiprofessional assessment seemed to have an impact on the accuracy of referrals for cases requiring surgical intervention.
Predictive models of weakness among older adults: the contribution of oral health indicators.
Mello ALSF, Pereira MC, Figueiredo DR … +3 more , D'Orsi E, Peres MA, Peres KG
Braz Oral Res · 2025 · PMID 41036888 · Full text
Poor oral health can negatively impact overall health and quality of life. Understanding how oral health predicts weakness in older adults is critical, since weakness increases the risk of health outcomes. However, the p...
Poor oral health can negatively impact overall health and quality of life. Understanding how oral health predicts weakness in older adults is critical, since weakness increases the risk of health outcomes. However, the predictive role of oral health indicators in weakness among older adults remains unclear. This study assessed the ability of oral health indicators to predict weakness using data from Brazil's EpiFloripa Aging cohort study. Predictive validity was evaluated in a sample of older adults participating in the cohort's second (n = 440) and third (n = 347) waves. Self-reported sociodemographic, general health, and oral health variables were analyzed, with weakness diagnosed using cut-off points for handgrip strength. Predictive models incorporating sociodemographic, general health, and oral health variables were tested. Receiver operating characteristic curves, sensitivity and specificity, and positive and negative predictive values were calculated. Approximately 45.9% of the participants had two to three compromised oral health indicators during the second wave, and the five-year incidence of weakness was 31.9%. Oral health indicators and the oral frailty score did not enhance the prediction of weakness compared to models based solely on demographic, socioeconomic, and general health variables. However, models including oral health indicators demonstrated predictive accuracy comparable to those with demographic, socioeconomic, and general health variables. Sensitivity values were low (3.70-6.48%), while specificity values were high (>99%), with accuracy ranging from 0.64 to 0.71. These findings suggest that oral health indicators offer comparable predictive validity for weakness as sociodemographic and general health models, potentially serving as useful tools for health teams in screening older adults for weakness.
Factors associated with the effectiveness of oral health promotion in the Family Health Strategy.
Paredes SO, Forte FDS, Lucena EHG … +2 more , Massoni ACLT, Galvão MHR
Braz Oral Res · 2025 · PMID 40960757 · Full text
This study investigated associations between sociodemographic and professional profiles, work-related factors, and the effectiveness of oral health promotion strategies implemented by dentists in the Family Health Strate...
This study investigated associations between sociodemographic and professional profiles, work-related factors, and the effectiveness of oral health promotion strategies implemented by dentists in the Family Health Strategy. A cross-sectional study was conducted with 211 dentists working in Oral Health Teams within the Family Health Strategy in the state of Paraíba, Brazil. Data were collected online using a validated instrument. A matrix encompassing the core values and pillars of health promotion was employed to evaluate the effectiveness of oral health promotion strategies. Data were analyzed using Poisson regression (p < 0.05), and all analyses were performed in Stata, version 14. Greater effectiveness of oral health promotion strategies was associated with mixed Oral Health Teams (urban and rural coverage) (PR = 1.54; 95%CI: 1.154-2.076; p = 0.003) and with dentists under temporary contracts (PR = 1.67; 95%CI: 1.240-2.250; p = 0.001). The effectiveness of oral health promotion strategies was associated with work-related factors. Evaluations of oral health promotion practices are essential to support improvements in oral health management. The findings highlight the need to strengthen these practices through professionals who, in addition to having a defined employment relationship and a structured work process, value oral health promotion as a key component of care.
Oral mucosal findings in ambulatory patients with inflammatory bowel disease.
Esquivel-Pedraza L, Fernández-Cuevas L, Delgado-Martínez I … +9 more , Cicero-Casarrubias A, Milke-García MDP, Chang-Bool EM, Barragán-Heredia LM, Maldonado-Molina J, Rivera-Flores RL, Yamamoto-Furusho JK, Domínguez-Cherit J, Méndez-Flores S
Braz Oral Res · 2025 · PMID 40960756 · Full text
A cross-sectional study was carried out among patients with ulcerative colitis (UC) and Crohn's disease (CD) in order to determine the frequency of oral mucosal lesions or conditions (OL), as well as to analyze its relat...
A cross-sectional study was carried out among patients with ulcerative colitis (UC) and Crohn's disease (CD) in order to determine the frequency of oral mucosal lesions or conditions (OL), as well as to analyze its relationship with some clinical and laboratory parameters. Epidemiologic, clinical, and laboratory data were considered. Statistics included univariate and multivariate analyses. Ninety patients [46 (51.1%) males] were included [median age: 43 years (range 18-79 years)]. UC was diagnosed in 65 (72.2%) patients; CD in 25 (27.8%) patients; and inactive CD was detected in 78 (86.6%) patients. All patients (100%) had OL; fissured tongue was the most frequent finding [68 (75.6%)]. Furred tongue was more common in UC than in CD patients [45 (69.2%) vs. 11(44.0%); p = 0.03]; lower levels of hemoglobin were more often detected in mucosal pallor [(median (Md) =12.1 vs. 14.4g/dL); p = 0.02] than in other OLs. Higher frequency of melanosis was observed when oral rinses were used [37 (71.2%) vs. 15 (28.8%)]; p = 0.03], compared to those who did not use them. A higher risk of varix [OR: = 37.6 (95%CI: 4.7-298.9), p < 0.001], leukoedema [OR: 5.8 (95%CI: 1.4-24.2); p = 0.004], candidosis [OR: 3.9 (95%CI: 1.4-10.6); p = 0.05], fissured tongue [OR: 3.8 (95%CI: 1.2-11.5); p = 0.01], and all infectious processes analyzed collectively [OR: 3.6 (95%CI: 1.3-9.8); p = 0.03], was found in patients older than 45 years than in younger ones. Also, patients with fissured tongue presented a higher risk of having candidosis than those without this condition [OR: 6.1 (95%CI: 2.1-17.5); p = 0.007]. OLs were highly frequently observed in UC and CD patients. Age (> 45 years), low levels of hemoglobin, use of mouthwashes, among other variables, were predictive factors of OL in these patients; thus, their assessment and detection in inflammatory bowel disease should be emphasized.
Polymorphisms and environmental factors associated with orofacial clefts as potential markers for oral cancer risk.
Silva AMD, Falcão MML, Freitas VS … +1 more , Vieira AR
Braz Oral Res · 2025 · PMID 40960755 · Full text
The etiological intersection between orofacial clefts and oral cancer may involve environmental factors modulating gene expression in shared biological pathways. This study aimed to investigate the association between or...
The etiological intersection between orofacial clefts and oral cancer may involve environmental factors modulating gene expression in shared biological pathways. This study aimed to investigate the association between orofacial clefts and oral potentially malignant disorders or oral squamous cell carcinoma, focusing on genetic variants and environmental risk factors. A case-control design was employed, comprising 48 histologically confirmed cases of oral potentially malignant disorders or oral squamous cell carcinoma and 96 age- and sex-matched controls. Information on family history of orofacial cleft, and biological and environmental risk factors, was collected through interviews. Genomic DNA was extracted from saliva samples and genotyped for rs1533767 (WNT11), rs9879992 (GSK3B), and rs3923087 and rs11867417 (AXIN2). Unadjusted and adjusted odds ratios (OR) for the associations between family history of orofacial cleft and oral potentially malignant disorders/oral cancer, and between environmental risk factors and oral potentially malignant disorders/oral cancer were calculated using STATA software. Genotype and allele frequency comparisons between groups were conducted using PLINK Software. Statistical significance was defined as p<0.05 and 95% confidence interval (95%CI). No statistically significant association was found between family history and orofacial clefts (p = 0.52). However, place of residence (adjusted OR:5.46, p < 0.001, 95%CI: 3.76-63.543), and three genetic variants-rs1533767 (OR: 1.94, p = 0.042, 95%CI: 1.018-3.694), rs3923087 (OR: 0.58, p = 0.038, 95%CI: 0.344-0.974), rs11867417 (OR: 0.51, p = 0.010, 95%CI: 0.304-0.857)-were associated with oral potentially malignant disorders and oral squamous cell carcinoma. These findings suggest that specific environmental risk factors and genetic variants may be associated with increased susceptibility to oral potentially malignant disorders and oral cancer.
Determinants of tooth loss among adolescents (15-19 years) from Minas Gerais, Brazil: a multilevel analysis.
Motta TPD, Knorst JK, Silveira ACVD … +4 more , Pinto RDS, Mota DGD, Abreu MHNG, Vargas-Ferreira F
Braz Oral Res · 2025 · PMID 40929412 · Full text
In this cross-sectional study, carried out in 2012, we assessed factors associated with tooth loss among adolescents from Minas Gerais, Brazil, utilizing data from a secondary database. Individual and local-level variabl...
In this cross-sectional study, carried out in 2012, we assessed factors associated with tooth loss among adolescents from Minas Gerais, Brazil, utilizing data from a secondary database. Individual and local-level variables were selected to represent health determinants. Individual covariates included sex, age, skin color, maternal education, household income, use of dental services, and self-perceived need for dental care. The contextual variables included illiteracy, unemployment, income, primary health care coverage, dental specialty centers, and oral health team coverage. Multilevel logistic regression models were used to examine the relationship between contextual and individual variables and the outcome (STATA version 16.0) - odds ratio (OR) and 95% confidence interval (CI). The prevalence of tooth loss was 12.4%. Female individuals were 40% more likely to experience the outcome (OR: 1.40; 95%CI: 1.01-1.98). Increased age was associated with greater tooth loss (OR: 1.16; 95%CI: 1.03-1.31). Low maternal education (OR: 1.72; 95%CI: 1.13-2.61), low household income (OR: 1.71; 95% CI 1.09-2.67), and self-perceived dental needs (OR: 2.94; 95% CI 1.97-4.39) were also associated with the outcome. Regular dental visits reduced the likelihood of tooth loss by 38% (OR: 0.62; 95 CI 0.44-0.87). Larger tooth loss was observed in municipalities with higher illiteracy rates (OR: 1.04; 95%CI: 1.01-1.08). Municipalities with larger dental specialty centers were associated with the outcome (OR: 0.58; 95%CI: 0.37-0.92). Contextual and individual factors influenced tooth loss in adolescents from Minas Gerais, Brazil, but socioeconomic status was the main determinant.
Frequency of recurrent injuries in the deciduous dentition and associated factors.
Oliveira NTJ, Santos-Silva P, Fernandes IB … +4 more , Assunção CM, Ferreira FM, Zarzar PM, Vieira-Andrade RG
Braz Oral Res · 2025 · PMID 40929411 · Full text
Understanding recurrent injuries in the deciduous dentition and possible associated factors could help in the control and prevention of such episodes in children. The aim of the present study was to investigate the frequ...
Understanding recurrent injuries in the deciduous dentition and possible associated factors could help in the control and prevention of such episodes in children. The aim of the present study was to investigate the frequency of recurrent injuries in the deciduous dentition and associated factors. A retrospective cross-sectional study was conducted involving 517 children aged between six months and six years treated at the Clinic for Traumatic Dental Injuries in the Deciduous Dentition of the School of Dentistry of the Universidade Federal de Minas Gerais. Data were collected from dental records with information on sociodemographic and clinical characteristics. Data analysis involved descriptive statistics, chi-square test, and bivariate and multivariate Poisson regression analyses (p < 0.05; 95%CI). The prevalence of recurrent tooth injuries in the deciduous dentition was 17.2% (n = 89). Children aged between four and six years (PR = 1.917; 95%CI: 1.055-3.484; p = 0.033), those with inadequate lip protection (PR = 1.790; 95%CI: 1.085-2.953; p = 0.023), those with uncomplicated crown and crown-root fractures (PR = 1.856; 95%CI: 1.224-2.816; p = 0.004), and those with complicated crown and crown-root fractures (PR = 1.818; 95%CI: 1.021-3.239; p = 0.042) had a greater frequency of repeated tooth injuries compared to children without these characteristics. In the present study, older age, inadequate lip coverage, and the occurrence of complicated and uncomplicated crown and crown-root fractures were associated with repeated injuries in the deciduous teeth.
Prevalence of temporomandibular disorders and associated factors: a population-based study in southern Brazil.
Silveira AM, Cericato GO, Meusel LDZV … +3 more , Girotto LPDS, Bacchi A, Silva-Sousa YTC
Braz Oral Res · 2025 · PMID 40929410 · Full text
The aim of this study was to assess the prevalence of temporomandibular disorder (TMD) and associated factors in an adult population in southern Brazil. The population-based sample (n = 4.65) included participants from P...
The aim of this study was to assess the prevalence of temporomandibular disorder (TMD) and associated factors in an adult population in southern Brazil. The population-based sample (n = 4.65) included participants from Passo Fundo, a town in southern Brazil. The Fonseca Anamnestic Index was used to establish the prevalence of TMD. Sociodemographic and pathophysiologic factors and those that could cause tissue injury (trauma) were investigated. Data were analyzed using the chi-square or Fisher's exact test and Poisson regression model (p < 0.05; 95%CI). The prevalence of TMD was 13.4%, and the most prevalent symptoms were pain in the neck and/or shoulders (30.1%), headache (26.0%), and presence of popping or clicking sounds (17.0%). None of the sociodemographic factors (sex, age, marital status, occupation, and education) were associated with the prevalence of TMD (p > 0.05). Among pathophysiologic factors, those associated with the prevalence of TMD were insomnia (PR: 1.83; 95%CI: 1.07-3.12), osteoporosis (PR: 2.50; 95%CI: 1.22-5.12), rheumatoid arthritis (PR: 1.99; 95%CI: 1.07-3.68), and xerostomia (PR: 1.36; 95%CI: 1.07-1.73). The factors that could cause tissue trauma/injury associated with TMD were sleep bruxism (PR: 2.16; 95%CI: 1.01-4.62), awake bruxism (PR: 2.44; 95%CI: 1.16-5.11), tongue pressure against the teeth (PR: 4.11; 95%CI: 1.95-8.65), and neck support of objects during work (PR: 2.94; 95%CI: 0.88-9.73). The prevalence of TMD was 13.44%, and it was associated with pathophysiologic factors and those that cause tissue trauma/injury, but not with sociodemographic factors.
Surface properties of direct restorations and adjacent dental tissues after saliva exposure.
Kunz PVM, Veiga RD, Camargo V … +3 more , Kaizer MDR, Correr GM, Gonzaga CC
Braz Oral Res · 2025 · PMID 40929409 · Full text
This study assessed the effect of saliva exposure on roughness (Ra) and Vickers hardness (VHN) of two direct restorative materials, enamel, and dentin adjacent to the restorations. Enamel and dentin cavities in molars (n...
This study assessed the effect of saliva exposure on roughness (Ra) and Vickers hardness (VHN) of two direct restorative materials, enamel, and dentin adjacent to the restorations. Enamel and dentin cavities in molars (n = 10) were restored with a) bulk-fill resin composite (Tetric N-Flow Bulk Fill, BF) with the application of a universal adhesive (Tetric N-Bond Universal) and b) alkasite restorative material (Cention N, CN) with and without the application of a universal adhesive. After 24 h (baseline), surface roughness and hardness of the restorative material and dental tissues were assessed at 100 μm from the tooth/restoration interface. The specimens were subjected to degradation in whole saliva for 7 days (combined with the application of 20% sucrose 10x/day). Ra and VHN were then reassessed. The data were analyzed by ANOVA and Tukey's test (α = 5%). BF exhibited a significantly lower Ra than CN. Ra increased significantly after degradation in saliva when compared to baseline values. Enamel hardness was higher for BF restorations. No differences in enamel hardness were observed for alkasite restorations with and without adhesive application. For dentin hardness, significantly lower values were found in alkasite restorations with previous application of an adhesive system. It can be concluded that BF had a smoother surface than CN before and after degradation. Immersion in saliva reduced the hardness of both restorative materials, enamel, and dentin adjacent to the restoration.
Follow-up of a 10-year period (2010-2020) of Down syndrome in Brazil.
Miranda RM, Paula JLS, Santos TRD … +2 more , Pinto RDS, Macari S
Braz Oral Res · 2025 · PMID 40929408 · Full text
This study aimed to determine the prevalence and provide an overview of Down syndrome and child- and mother-associated factors in Brazil from 2010 to 2020. This was a cross-sectional study including epidemiological chara...
This study aimed to determine the prevalence and provide an overview of Down syndrome and child- and mother-associated factors in Brazil from 2010 to 2020. This was a cross-sectional study including epidemiological characteristics related to live births of individuals with and without Down syndrome using the Brazilian government website. The average prevalence of Down syndrome in Brazil was approximately 30.4 children per 100,000 live births during the 10-year period, corresponding to 1 case in every 3,289.47 newborns. The occurrence of Down syndrome was increased in White children, preterm births, and low birth weight infants compared to the no-Down syndrome group; however, it was decreased in males. The prevalence of Down syndrome was low among mothers without a spouse, insufficient prenatal care, and vaginal delivery. Conversely, the prevalence was high among mothers aged 35 years and older and mothers considered White. There was no evidence of a time correlation in the prevalence among the regions of Brazil during this 10-year period. It is imperative to strengthen national monitoring of the prevalence of children with Down syndrome and provide better support to mothers and public services for this group.
Effects of cone-beam computed tomography with different FOV parameters on simulated internal root resorption volume.
Bağci N, Büyüksungur A, Kurt MH
Braz Oral Res · 2025 · PMID 40929407 · Full text
The aim of this in-vitro study was to verify which field of view (FOV) in cone-beam computed tomography (CBCT) yields greater accuracy in the detection of internal root resorption (IRR) volume, in comparison to the gold...
The aim of this in-vitro study was to verify which field of view (FOV) in cone-beam computed tomography (CBCT) yields greater accuracy in the detection of internal root resorption (IRR) volume, in comparison to the gold standard of micro-computed tomography (micro-CT) and to a physical method. Twenty-five extractedsingle-rooted teeth were scanned by CBCT with two different FOV parameters (6x6-FOV and 10x10-FOV) and via micro-CT. The volume of dental hard tissue was measured on these images. A simulated IRR was produced by a demineralization protocol. After the simulated IRR, the volumes of the dental hard tissue and the simulated IRR were measured with the same scanning parameters. In addition, the volume of the simulated IRR was measured via a physical method. The simulated IRR volumes obtained by CBCT, micro-CT, and the physical method were statistically compared using one-way ANOVA. Before the simulated IRR, the mean volume of dental hard tissue obtained by 6x6-FOV, 10x10-FOV, and micro-CT were 266.64 ± 11.56, 284.78 ± 14.99, and 233.07 ± 19.91, respectively. The simulated IRR mean volumes obtained by 6x6-FOV, 10x10-FOV, micro-CT, and the physical method were 19.35 ± 5.92, 17.43 ± 5.20, 23.85 ± 6.63, and 13.51 ± 3.11, respectively. The mean volume of the simulated IRR obtained by micro-CT was similar to that of the 6x6-FOV and was significantly different from that of the 10x10-FOV and physical method. The mean volume value of simulated IRR obtained by the physical method was significantly different from those of the micro-CT and 6x6-FOV groups. In conclusion, the 6x6-FOV was better than the 10x10-FOV for the detection of IRR volume by CBCT under clinical conditions.
Effects triggered by tumor necrosis factor-α in immortalized murine dental pulp and pre-osteoblastic cells.
Lamarque GCC, Leme RD, Almeida Junior LA … +5 more , Lucisano MP, Bombonato-Prado KF, Segato RAB, George A, Paula-Silva FWG
Braz Oral Res · 2025 · PMID 40929406 · Full text
Tumor necrosis factor-alpha (TNF-α) is a cytokine involved in the immune-inflammatory response. It can induce an odontoblastic phenotype and enhance biomineralization in dental pulp mesenchymal stem cells but does not ha...
Tumor necrosis factor-alpha (TNF-α) is a cytokine involved in the immune-inflammatory response. It can induce an odontoblastic phenotype and enhance biomineralization in dental pulp mesenchymal stem cells but does not have the same effect on osteoblasts. The reasons for this differential response, despite the shared lineage of these cell types, are not yet clear. This study examined the effects of TNF-α on immortalized mouse dental pulp stem cells (OD-21) and pre-osteoblastic cells (MC3T3-E1). Cells were treated with recombinant TNF-α at concentrations of 1, 10, and 100 ng/mL. Cell viability, proliferation, and migration were assessed using the MTT, CyQUANT, and wound healing assays, respectively. Gene expression was assessed via real-time RT-PCR, and biomineralization was evaluated using alizarin red staining. Statistical analysis was conducted using one-way ANOVA followed by Tukey's post-hoc test (α = 0.05). TNF-α did not affect cell viability at any concentration (p > 0.05). Proliferation and migration increased after 12 h, with near-complete wound closure by 24 h. TNF-α promoted proliferation and migration in both cell types. OD-21 cells exhibited high levels of Tnfr1 and Runx2 expression and showed biomineralization. In contrast, MC3T3-E1 cells showed high Tnfr2 levels, suppressed Runx2, and inhibited biomineralization. These results highlight how TNF-α influences different cell types from the same lineage in distinct ways.
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