Zhonghua Er Bi Yan Hou Ke Za Zhi[JOURNAL]
Sun
200 papers
[Anteroposterior cricoid split interposition grafting for severe glottic and subglottic stenosis].
Chen WX, Ruan YY, Li GZ … +4 more , Cui PC, Sun YZ, Guo WH, Gao PF
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Apr · PMID 15283279
OBJECTIVE: To study the effect of anterior and posterior cricoid splitting interposition grafting for severe glottic and subglottic stenosis. METHODS: This is a retrospective study, from 1991 to 2001 years, 25 patients (...
OBJECTIVE: To study the effect of anterior and posterior cricoid splitting interposition grafting for severe glottic and subglottic stenosis. METHODS: This is a retrospective study, from 1991 to 2001 years, 25 patients (male 15, female 10, aged 9 to 46 years) with severe glottic and subglottic stenosis were operated with anterior and posterior cricoid splitting interposition grafting method at Tangdu Hospital. All of 25 patients were tracheostomy dependent before reconstruction. 19 patients had previously undergone 1 to 7 (average 2) surgical procedures. The surgical technique consisted of laryngotracheostomy, cricoid lamina midline vertical incision; rib cartilage graft (17 cases), muscular fasciae, perichondrium or split-thickness skin graft (15 cases), pedicle arytenoid cartilage graft (2 cases) and thyroid cartilage graft (1 case) interposition and silicon T-tube stenting for 3 to 6 months. RESULTS: Twenty-four patients (96%) were successfully decannulated and got an effective phonation. One patient failed decannulation. The follow-up period ranged from 1 to 10 years. All of the 24 patients had a stable airway and effective phonation. CONCLUSIONS: The anteroposterior cricoid split interposition graft technique was a safe and effective method for the treatment of severe glottic and subglottic stenosis. Careful split of the cricoid, avoiding injury of esophageal musculature, careful hemostasis, a tight suture graft and using stent were the keys of successful operation.
[Long-term follow-up of autogenous fat injection for unilateral vocal cord paralysis].
Wen W, Zhou SM, Yang XQ … +3 more , Shen XH, Sun GB, Gen LP
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Apr · PMID 15283278
OBJECTIVE: To study the long-term results of autogenous fat injection for unilateral vocal cord paralysis. METHODS: Twenty cases with unilateral vocal cord paralysis were treated by autogenous fat injection into the thyr...
OBJECTIVE: To study the long-term results of autogenous fat injection for unilateral vocal cord paralysis. METHODS: Twenty cases with unilateral vocal cord paralysis were treated by autogenous fat injection into the thyroarytenoid muscle to achieve medialization. The patients were divided into 3 groups by hoarse degree before operation, all of them were followed more than 12 months with serial video laryngoscope and voice evaluation. The ratio between paralyzed vocal cord upper surface and that of the normal vocal cord were adopted as the measurement for the vocal cord volume changes before and after operation. RESULTS: 1. The volume of paralyzed vocal cord was increased. The degree of hoarse and normalized noise energy (NNE) were evaluated by objective methods after operation. 2. The hoarse symptom was less severe after operation than that before operation. The cure cases 3 to 6 months and over 12 months after operation were nearly the same. 3. NNE of over 12 months and 3 to 6 months after operation were not significantly different, but the postoperative NNE were different with that before operation. CONCLUSIONS: Autologous fat injection was an effective method for treating unilateral vocal cord paralysis, and the long term effects were reliable.
[Surgery for velopharyngeal insufficiency: a review of 219 modified pharyngoplasties].
Wang GM, Yang YS, Chen Y … +3 more , Wu YL, Jiang LP, Liu Q
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Apr · PMID 15283277
OBJECTIVE: Two-hundreds and nineteen velopharyngeal insufficiency cases treated with a modified pharyngoplasty were retrospectively analyzed, the effectiveness of the surgery was studied. METHODS: Two-hundreds and ninete...
OBJECTIVE: Two-hundreds and nineteen velopharyngeal insufficiency cases treated with a modified pharyngoplasty were retrospectively analyzed, the effectiveness of the surgery was studied. METHODS: Two-hundreds and nineteen patients (111 males, 108 females, range from 4 to 33 years, mean age 14.2 years) with velopharyngeal insufficiency were studied. Among 219 patients, 44 with congenital velopharyngeal insufficiency, 21 with fistula after palatoplasty and 154 with velopharyngeal insufficiency after primary palatoplasty. All cases had special examination, Chinese speech intelligibility test and blowing test before and after modified pharyngoplasty. RESULTS: Hypernasality in all cases were reduced and blowing test increased with various degrees. The Chinese speech intelligibility rose from 41% to 63%. CONCLUSIONS: The modify pharyngoplasty is a safe and effective method for velopharyngeal insufficiency of patient.
[Oropharyngeal measure in patients with obstructive sleep apnea-hypopnea syndrome before and after uvulopalatopharyngoplasty].
Cai Q, Ye H, Zheng YQ … +4 more , Liu X, Su ZZ, Fu YG, Chen HH
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Apr · PMID 15283276
OBJECTIVE: To explore the relationship between the extent of enlarged oropharynx and efficiency through measuring the anterior-posterior and transverse diameter of oropharynx of patients with obstructive sleep apnea-hypo...
OBJECTIVE: To explore the relationship between the extent of enlarged oropharynx and efficiency through measuring the anterior-posterior and transverse diameter of oropharynx of patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) before and after uvulopalatopharyngoplasty (UPPP). METHODS: Thirty eight patients with OSAHS were studied. The following indexes were measured before and after UPPP: width of uvula base, length of uvula, distance between uvula and posterior pharyngeal wall (DBUP), distance between anterior pillar (DBPP), apnea-hypopnea index (AHI), body mass index (BMI) and SaO2. RESULTS: The preoperative DBAP and DBPP were significantly less than those of normal adults (P < 0.05). DBUP, length of uvula and width of uvula base has no significant difference between preoperative patients and normal adults (P > 0.05). There was no significance difference in DBAP. DBPP and DBUP between postoperative patients and normal adults (P > 0.05). The preoperative AHI, IBM, minimal SaO2, mean SaO2, DBUP, DBPP, DBAP, length of uvula and width of uvula base has no significant difference between good responders and nonresponders (P > 0.1). CONCLUSIONS: Transverse diameter of OSAHS patients is shorter than that of normal adults but anterior-posterior diameter of OSAHS patients has no difference compared with normal adults. Transverse diameter could be enlarged by UPPP. Not only anatomical abnormality but also other factors will contribute to the effect of UPPP.
[Diseases of the throat and phonosurgery].
Guo ZX, Wang RG, Yang WY
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Apr · PMID 15283275
Abstract loading — click title to view on PubMed.
[Guideline of Cochlear implantation and development of otology].
Yang WY
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Feb · PMID 15272507
Abstract loading — click title to view on PubMed.
[Gastroesophageal reflux and chronic pharyngitis].
Wang XW, Ni DF
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Jan · PMID 15237545
Abstract loading — click title to view on PubMed.
[Evaluation of the serum endothelin-1 level and sleep architecture change in patients with obstructive sleep apnea hypopnea syndrome accompanied hypertension].
Li YZ, Wang TC, Lu HX … +3 more , Wang X, Wang Y, Zhang BF
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Feb · PMID 15195597
OBJECTIVE: To explore the role of endothelin-1 (ET-1) in the pathogenesis of hypertension in obstructive sleep apnea hypopnea syndrome (OSAHS). METHODS: The levels of serum ET-1 in 30 OSAHS patients accompanied by hypert...
OBJECTIVE: To explore the role of endothelin-1 (ET-1) in the pathogenesis of hypertension in obstructive sleep apnea hypopnea syndrome (OSAHS). METHODS: The levels of serum ET-1 in 30 OSAHS patients accompanied by hypertension, 30 normotensive OSAHS patients and 30 healthy controls were measured by ET-1 enzyme immunoassay kit. Meanwhile the correlation about the concentration of ET-1 in OSAHS patients with the clinic, polysomnography (PSG) parameters was analyzed. RESULTS: OSAHS patients with or without hypertension compared with snoring group and normal people, the sleep structure was significantly disturbed. The time percentages of awake and stage I sleep were increased, while stage II sleep decreased significantly in OSAHS patients than those in snoring group (P < 0.01, respectively). There were no significantly difference about the sleep structure in the two OSAHS groups. The levels of serum ET-1 (mean +/- s) were significantly higher in OSAHS patients accompanied by hypertension and normotensive OSAHS patients(42.5 +/- 8.4) ng/L and (38.6 +/- 4.7) ng/L respectively than those in the healthy controls(33.1 +/- 5.4) ng/L (P < 0.01, respectively). In the two OSAHS groups, the levels of serum ET-1 were significantly higher in OSAHS patients accompanied by hypertension than those in the normotensive OSAHS patients (P < 0.05). There were positive correlations between the concentration of ET-1 and the apnea hypopnea index (AHI) in all the 60 OSAHS patients with and without hypertension (r = 0.334, P < 0.01). There were negative correlations between the concentration of ET-1 and the lowest oxygen desaturation in all the 60 OSAHS patients with and without hypertension (r = -0.230, P < 0.05). CONCLUSION: These results indicate that the sleep disordered breathing and hypoxia may contribute to the elevation of ET-1 in the OSAHS patients and OSAHS patients accompanied by hypertension. ET-1 may play an important role in the pathogenesis of OSAHS-induced hypertension.
[Effect of specific immunoglobulin Y in the treatment of acute and chronic pharyngitis].
Xie MQ, Meng YX, Li ZH … +5 more , Li YQ, Zhang KX, Zhao XM, Xiong GJ, Chen YM
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Feb · PMID 15195596
OBJECTIVE: To evaluate the effect and safety of the specific immunoglobulin Y (IgY) for treatment of acute and chronic pharyngitis. METHODS: Double-blind, randomized, placebo-controlled trial was conducted on 50 adults w...
OBJECTIVE: To evaluate the effect and safety of the specific immunoglobulin Y (IgY) for treatment of acute and chronic pharyngitis. METHODS: Double-blind, randomized, placebo-controlled trial was conducted on 50 adults with acute pharyngitis. Experimental group received a 6 times-daily total 30 doses of IgY stomat-spray which contained specific immunoglobulin Y (titer = 512) prepared from the egg yolk of hens immunized with a variety of bacteria. Another open label trial included 50 patients, whose ages ranged from 21-69 years, including 25 cases of acute pharyngitis and 25 cases of chronic pharyngitis were also treated using IgY stomat-spray. The therapeutic effect were objectively evaluated 7 days later by the decreased scores based on both the symptoms and physical signs. If the symptom did not improve or became severe three days later, these patients with acute pharyngitis was inefficiency and antibiotic medicine would be added to them. RESULTS: In Double-blind trial, 8 cases (32%) received IgY had apparent effect with the decreased scores 5 or more than 5, 13 cases (52%) had effective with the decreased scores 3-4, and other 4 cases (16%) had inefficacy with the decreased scores only 2 or no more than 2. While in placebo-controlled group, only 2 (8%) cases had apparent effect, 5 (20%) cases showed effective and 18 (72%) cases had non-effect. The difference between the two groups was significant (chi 2 = 16.06, P < 0.01). In open label trial, 19 cases (38%) showed apparent effect, in which 14 cases were acute pharygitis. 23 cases (46%) had effective, in which 10 cases were acute pharyngitis. The left 8 cases (16%) had ineffective, in which one case was acute pharyngitis. There was significantly difference (chi 2 = 8.90, P < 0.05) between acute pharyngitis and chronic pharyngitis. An average of three months followup showed that there were no side effect or toxic effect and no allergic reaction. CONCLUSION: The IgY stomat-spray is a safe and effective agent in treating acute and chronic pharyngitis, especially for acute pharyngitis.
[Transnasal endoscopic frontal surgery for chronic frontal sinusitis].
Shi JB, Xu G, Yang QT … +3 more , Wang T, Chen HX, Wen WP
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Feb · PMID 15195595
OBJECTIVE: The recurrence of chronic frontal sinusitis after endoscopic surgery is mainly due to the mismanagement of frontal recess and frontal sinus orifice. The aim of this study is to investigate the characteristics...
OBJECTIVE: The recurrence of chronic frontal sinusitis after endoscopic surgery is mainly due to the mismanagement of frontal recess and frontal sinus orifice. The aim of this study is to investigate the characteristics of chronic frontal sinusitis and to advance the clinical therapeutic efficacy. METHODS: Different methods were used to manage different local diseases in frontal sinus orifice or frontal recess in 58 cases (96 sides) with chronic frontal sinusitis by nasal endoscopic surgery. RESULTS: Different degree of middle meatal obstruction was seen in all cases at operation. The situation of frontal sinus ostium and frontal recess was as follows: 38 sides obstructed by swollen mucosa, polypoid mucosa or polyps, no cell obstruction at frontal sinus orifice; 34 cases constricted by over development of agger nasi cells, ethmoid bulla or terminal cell at frontal recess; 15 cases obstructed completely by over development cells at frontal recess; osteal stenosis at frontal sinus orifice in 9 cases. The situation in frontal sinus was as follows: pus accumulation in 18 sides, mucosal swollen in 21 sides, mucosal congestion in 49 sides, no obvious mucosal diseases in 8 cases. Follow-up for 6-20 months showed that 69 sides (71.9%) were cured, 17 sides (17.7%) better and 10 cases (10.4%) recurrent. CONCLUSION: Obstruction of osteomeatal complex and frontal recess is the main causes of chronic sinusitis. There are four pathologic states in obstruction of frontal recess and frontal ostium. Different operative methods should be taken according to different pathological changes. The operative effects is still needed to improve.
[Immunoblot and immunohistochemical analysis of CYP2A expression in human olfactory mucosa].
Liu YQ, Chen Y, Ren X … +1 more , Shi L
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Feb · PMID 15195594
OBJECTIVE: To investigate the nasal expression of CYP2A proteins in human. METHODS: Immunoblot analysis was used to detect fetal tissues at 96-185 days of gestational age and in surgical biopsy tissues from different reg...
OBJECTIVE: To investigate the nasal expression of CYP2A proteins in human. METHODS: Immunoblot analysis was used to detect fetal tissues at 96-185 days of gestational age and in surgical biopsy tissues from different regions of nasal cavity of 36 adult patients, and immunohistochemical methods were used to localize CYP2A proteins' cellular distribution. RESULTS: In adults, CYP2A protein was detected in olfactory microsomes from 8 of 10 individual, but not in the respiratory nasal microsomes from 37 individual. Quantitative immunoblot analysis confirmed that CYP2A proteins were selectively expressed in the olfactory region in both adult and fetal tissues. Interestingly, the levels of CYP2A proteins in nasal microsomes were generally higher in fetuses than in adults. The CYP2A protein content in olfactory microsomes ranged from 0.1 to 1.1 pmol/mg among adult nasal microsomes, while among five fetuses ranged from 0.8 to 5.3 pmol/mg microsomal protein, with a trend of developmental increase in expression level. Immunohistochemical studies confirmed that the CYP2A proteins were expressed in the supporting cells in the olfactory epithelium and in the Bowman's glands in the lamina propria. CONCLUSIONS: CYP2A proteins expression in human olfactory mucosa indicates that olfactory mucosa is metabolic target site of the xenobiotics. Also CYP2A has a relationship with olfaction. The prenatal expression of the CYP2A proteins in the OM suggests potential risks of developmental toxicity from maternally derived xenobiotics.
Investigation of postoperation complications of the congenital aural atresia.
Zheng YL, Guo JZ
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Feb · PMID 15195593
OBJECTIVE: To investigate the treatments and complications of the congenital aural atresia. METHODS: Form 1996 to 2002, 446 ears with congenital aural atresia underwent operations in the Otolaryngology Department of the...
OBJECTIVE: To investigate the treatments and complications of the congenital aural atresia. METHODS: Form 1996 to 2002, 446 ears with congenital aural atresia underwent operations in the Otolaryngology Department of the Tongren Hospital. During the follow up from 6 months to 5 years, 47 ears occurred postoperative complications, which can be divided into five groups: external acoustic pore stenosis, external auditory canal stenosis, hearing loss, facial nerve palsysis. The hearing results of these 43 ears showed 12 ears had a decrease of 10 dB, 19 ears of 20 dB, 12 ears of 30-40 dB. RESULTS: The causes of complications mainly were insufficient opening of bony external canal, secondary infection and lateral healing of the transplanted tympanic membrane, and the surgeon did not master the anatomic characters of the abnormal facial nerve. Forty-three ears received operation again, including 24 ears with external acoustic pore stenosis, 9 ears with external auditory canal stenosis, 8 ears with hearing loss and 1 ear with facial nerve palsysis. Hearing improvement was found in 43 ears (100%) in which 10 ears (23.3%) with improvement of 10-20 dB, 21 ears (48.8%) of 20-30 dB, 12 ears (27.9%) of 30-40 dB. The one ear with facial nerve palsysis recovered 2 months after operation. CONCLUSION: External auditory canal stenosis and lateral healing of the transplanted tympanic membrane are the primary causes of postoperative hearing loss. Do not injure the facial nerve for hearing improvement in cases of facial nerve abnormalities.
Experimental studies for botulinum toxin type A on allergic rhinitis in the rat.
Wen WD, Yuan F, Hou YP … +1 more , Song YF
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Feb · PMID 15195592
OBJECTIVE: To study the effect of botulinum toxin-A on inhibiting rhinorrhea, on expression of VIP at nasal mucosa, on morphometrical change with an immunohistochemical and histological methods in rats allergic rhinitis....
OBJECTIVE: To study the effect of botulinum toxin-A on inhibiting rhinorrhea, on expression of VIP at nasal mucosa, on morphometrical change with an immunohistochemical and histological methods in rats allergic rhinitis. METHODS: Ovalbumin sensitized the rat as animal model of allergic rhinitis. Animals were divided into control group (n = 8), allergic group (n = 12), allergic animal treated by BTX-A group (n = 6). VIP immunoreactivity at nasal mucosa in the rat allergic rhinitis was studied by immunohistochemical. The morphometrical changes at nasal mucosa were observed by histological staining methods. RESULTS: The results showed that the symptoms of allergic rhinitis, nasal rhinorrhea and sneezing, were remarkably relieved after ovalbumin application in the rat. The nasal rhinorrhea symptom diminished after BTX-A treated. The quantity of nasal secretion were significantly reduced(P < 0.05) in allergic one treated by BTX-A group as compared with allergic group. Hematoxylin and eosin staining demonstrated that no edema, small vessels were found in the nasal mucosa and after BTX-A treatment, but edema, vasodilational and inflammational cell infiltration were observed in the allergic group. Immunohistochemical study revealed that VIP immunoreactive fibers in the nasal mucosa showed a marked decrease after BTX-A application, but the density and a large number of VIP fibers were significantly found in the allergic group. CONCLUSION: The results suggested that local BTX-A treatment was a selective and non-traumatic method to reduce a long lasting desensitization of the nasal mucosa, to alleviate nasal congestion, rhinorrhea and sneezing, and to reduce the sensory neuron sensitivity of the mucosa.
[Expression of substance P receptor positive cells in the Corti's organ with acute middle ear infection in guinea pigs].
Qiu JH, Liu SL, Su Y … +1 more , Qiao L
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Feb · PMID 15195591
OBJECTIVE: To investigate the expression of substance P receptor(SPR), SPR positive cells in the Corti's organ with acute middle ear infection in guinea pigs using the polyclonal antibody of SPR. METHODS: Twelve healthy...
OBJECTIVE: To investigate the expression of substance P receptor(SPR), SPR positive cells in the Corti's organ with acute middle ear infection in guinea pigs using the polyclonal antibody of SPR. METHODS: Twelve healthy guinea pigs were employed in the experiment. After general anesthesia, by injecting 1 x 10(8)/L staphylococcosis aureus into the middle cavity of right ear with the left ear serving as control, the acute middle ear infection model was established. Then three days later, immunohistochemical staining of SPR was performed in the Cochlear base membrane preparation. RESULTS: Microscopic examination of whole cochlear preparation revealed a number of SPR positive cells expression in the cochlear base membrane, these labeled cells usually did not exist in normal cochlear tissue. Obvious difference in morphology and distribution could be identified with inner hair cells, outer hair cells vascular endothelial cell and spiral ganglion neurons. Labeled SP receptor positive cells were similar to "neurons", scattering distributed in the free margin of cochlear base membrane, with larger size and multiple projections which was 6-12 times than the erythrocyte. There were the vesicle and granular substances in the cytoplasm of the labeled cells. CONCLUSIONS: Acute middle ear infection could induce the expression of SP receptor positive nonspecific cells in the Corti's organ of guinea pigs. These cells did not exist in the normal base membrane and might participate in initiating or inducing the immune response of inner ear.
[Multi-channel cochlear implants in patients with Mondini malformation].
Li YX, Han DM, Zhao XT … +8 more , Chen XQ, Kong Y, Zheng J, Liu B, Liu S, Mo LY, Zhang H, Wang S
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Feb · PMID 15195590
OBJECTIVE: To describe clinical experiences with multi-channel cochlear implantation in patients with Mondini malformation. METHODS: Among 300 patients who received multi-channel cochlear implants from 1996 to 2002 in Be...
OBJECTIVE: To describe clinical experiences with multi-channel cochlear implantation in patients with Mondini malformation. METHODS: Among 300 patients who received multi-channel cochlear implants from 1996 to 2002 in Beijing Tongren Hospital, 15 patients were diagnosed with Mondini malformation. A retrospective analysis was performed dealing with the surgical techniques, mapping and rehabilitations characteristics after surgery. 15 patients with normal cochlear structure are consider as control group. RESULTS: Gusher is found more common than the normal cochlear implantation, most of them are serious. The electrodes are inserted in the "cochleostomy" in full length of 13 Patients, 2 pairs of electrodes remains outside of "cochleostomy" in 2 patients. No serious complications occurred after implantation. All patients have auditory sensations. The impedance of the electrodes, the T level, C level and the hearing threshold are similar with the normal cochlear implantation group. The results have no significant difference in compare with normal cochlear group(P > 0.05). CONCLUSION: Multi-channel cochlear implantation could be performed safely in patients with Mondini malformation. The primary outcome for patients with Mondini malformation are similar to those with normal cochlear structure following the multi-channel cochlear implantation.
[Cochlear implant in patients with congenital malformation of inner ear].
Han DY, Wu WM, Xi X … +2 more , Huang DL, Yang WY
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Feb · PMID 15195589
OBJECTIVE: To study surgical difficulty and key of the cochlear implant in patients with congenital malformation of inner ear. METHODS: The cochlear implantations were performed in our department from Jan. 2001 to Apr. 2...
OBJECTIVE: To study surgical difficulty and key of the cochlear implant in patients with congenital malformation of inner ear. METHODS: The cochlear implantations were performed in our department from Jan. 2001 to Apr. 2003 for 18 patients with the malformation of inner ear. RESULTS: In this series, there were 11 cases of large vestibular aqueduct syndrome (LVAS), 3 cases of Waardenberg syndrome, 3 cases of Mondini malformation, and 1 case of Usher syndrome. All 18 patients accepted the Nucleus 24-channel cochlear implantations, including Nucleus straight electrode in 13 cases but Contour implantation in 5 cases of LVAS. During operations, leakage of perilymph but not cerebrospinal fluid (CSF) from the open of scala tympani occurred in 11 cases of LVAS, however, the electrode was inserted successfully. The abnormalities of round window occurred in one of 3 cases of Waardenberg syndrome and 3 cases of Mondini malformation, respectively. CONCLUSION: The cochlear implant could be conducted successfully for the LVAS, and the postoperative effect was same as the ones for the deafness persons with normal development of inner ear. However, for the patients with Mondini syndrome and common cavity, it is important to accurately assess the extent of abnormalities in the inner ear and accompanied malformation before operation, and to evaluate the full extent of difficulties of the operation in order to minimize the risk of CSF leakage and meningitis.
[Image examination of postoperative evaluation for the cochlear implanted electrode].
Kong WJ, Ma H, Han P … +4 more , Yue JX, Xiong XG, Zhu LX, Dai CK
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Feb · PMID 15195588
OBJECTIVE: To evaluate the image feature of the X-ray plain film, the spiral computed tomography (CT) scans and three dimension reconstruction of inner ear with implanted electrode. METHODS: Eighteen patients of cochlear...
OBJECTIVE: To evaluate the image feature of the X-ray plain film, the spiral computed tomography (CT) scans and three dimension reconstruction of inner ear with implanted electrode. METHODS: Eighteen patients of cochlear implant (MEDEL Combi 40+) recipients were involved in this study. The implanted electrode of all patients were examined on the fifth to seventh postoperative day, by the use of X-ray plain film with either anteroposterior transorbital projection (nine cases) or lateral position with coronal 60 degrees away from the examine table (nine cases). Three of the cochlear implant recipients were examined by the way of spiral CT scans with axial 1 mm image slices. The data of the CT scans was transferred to workstation for three-dimensioned reconstruction (direct volume rendering) of the inner ear. RESULTS: The X-ray plain film from both of anteroposterior projection and lateral with coronal 60 degrees projection provide satisfactory image of implanted electrode including the shape and the position in the temporal bone. The insertion depth of the electrode can be evaluated indirectly. In contrast, the images from CT scans with 3D reconstruction of the inner ear demonstrate more accurately the shape, the position, and the insertion depth of the electrode. Moreover, each of the electrode pairs can be identified clearly. CONCLUSIONS: X-ray plain film can meet the routine needs of postoperative evaluation of the implanted electrode with several kinds of head position of projection. But CT scans with 3D reconstruction of inner ear provide more accurate image of the spacial relationship of the electrode in the cochlear canal with direct demonstration of electrode insertion depth in the cochlea.
[Refractory recovery function of electrical auditory on the survival auditory nerve in cochlear implant recipients].
Xi X, Ji F, Han DY … +3 more , Huang DL, Hong MD, Yang WY
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Feb · PMID 15195587
OBJECTIVE: To evaluate the cochlear implant recipient's electrical auditory temporal properties in order to estimate the maximum stimulating rate which can be reached when they adopted some speech coding strategies based...
OBJECTIVE: To evaluate the cochlear implant recipient's electrical auditory temporal properties in order to estimate the maximum stimulating rate which can be reached when they adopted some speech coding strategies based on time mechanism, such as continuous interleaved sampling (CIS). METHODS: Thirty-eight Nucleus CI24 cochlear implant recipients were divided into 4 groups by etiology and history. Their survival auditory nerve fibers' refractory recovery time function was measured via neural response telemetry (NRT). Electrical pulses with the amplitude of recipient's loudest acceptable presentation were stimulated in mono-polar mode, with the width of 25 microseconds and the frequency of 80 Hz. Least-squares regression procedures were used to fit individual recovery functions with the equation A = C + K e(-t/tau), in which tau is the time constant of recovery from refractory state. Statistic analysis showed the relationship between the time constants of individuals and etiology as well as electrode position in the cochlea. RESULTS: Congenital deaf patient's recovery time constants were shorter than that of postnatal deaf groups of ototoxicity (P = 0.0056) and large vestibular aqueduct syndrome (P = 0.0349). There was no significant difference between the recovery time constants of congenital deaf patients and those of group with long history of deafness. The ANOVA of the recovery time constants of 5th, 10th, 15th electrode showed no significant statistical difference (P > 0.05). CONCLUSION: The recovery time constants are related with etiology. In mono-polar mode, the time constants of congenital deafness or subjects with short duration of deafness are shorter than those of postnatal deafness or subjects with long duration of deafness. Time constants do not vary systematically with electrode location along the implanted array. The reciprocal of individual electrode seems to be used in determining the maximum of stimulating rate of CIS strategy and as criteria of choosing the usable channels from 22 electrode bands.
[Tone recognition and electrode discrimination in prelingually deafened cochlear-implant listeners].
Wei CG, Cao KL, Chen XW … +3 more , Jin X, Zheng ZY, Zeng FG
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2004 Feb · PMID 15195586
OBJECTIVE: To investigate tone recognition and electrode discrimination in prelingually deafened children with the Nucleus device, and to develop guidelines for customized mapping in the implant users. METHODS: Fourteen...
OBJECTIVE: To investigate tone recognition and electrode discrimination in prelingually deafened children with the Nucleus device, and to develop guidelines for customized mapping in the implant users. METHODS: Fourteen prelingually deafened children with cochlear implants participated in this study. Tone recognition was measured with a four-alternative, forced choice procedure from 25 consonant-vowel syllables, each of which had four tonal variations. Electrode discrimination was measured using a same-difference procedure on 7 pairs of electrodes covering the entire electrode array. RESULTS: Tone recognition ranged from 35% to 99% correct with a mean of 62.8% and standard deviation of 14.7% in these users. Electrode discrimination had the mean threshold of 3.4 +/- 0.9, with the best performance from the middle electrodes (E 14 and E 17) at 2.6 and the followed performance at the most apical electrode (E 20). CONCLUSION: The results showed significant individual differences from both tone recognition and electrode discrimination, but there is significant correlation between them.
[The basic clinical research of head-neck neoplasms].
Zhao QZ
Zhonghua Er Bi Yan Hou Ke Za Zhi · 2003 Dec · PMID 15129694
Abstract loading — click title to view on PubMed.
About
- Frequency
- Sun
- Papers found
- 200
- RSS feed
- Subscribe